An inducible autocrine cascade regulates rat hepatocyte... : Hepatology (original) (raw)

Liver Biology/Pathobiology

An inducible autocrine cascade regulates rat hepatocyte proliferation and apoptosis responses to tumor necrosis factor‐α†‡

Cosgrove, Benjamin D.1,3,4; Cheng, Connie5; Pritchard, Justin R.2,3; Stolz, Donna B.6; Lauffenburger, Douglas A.1,2,3,4; Griffith, Linda G.*,1,4,§

1 Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA

2 Department of Biology, Massachusetts Institute of Technology, Cambridge, MA

3 Department of Cell Decision Processes Center, Massachusetts Institute of Technology, Cambridge, MA

4 Department of Biotechnology Process Engineering Center, Massachusetts Institute of Technology, Cambridge, MA

5 School of Engineering and Applied Sciences, Harvard University, Cambridge, MA

6 Departments of Cell Biology and Physiology, University of Pittsburgh, Pittsburgh, PA

Dept. of Biological Engineering, M.I.T., Room 16‐429, 77 Massachusetts Avenue, Cambridge, MA 02139===

Received October 19, 2007

Accepted March 11, 2008