Not interferon, but interleukin‐6 controls early gene... : Hepatology (original) (raw)

Viral Hepatitis

Not interferon, but interleukin‐6 controls early gene expression in hepatitis B virus infection†‡

Hösel, Marianna1,2; Quasdorff, Maria3,4; Wiegmann, Katja4; Webb, Dennis1,4; Zedler, Uta1,4; Broxtermann, Mathias5; Tedjokusumo, Raindy5; Esser, Knud1,5; Arzberger, Silke5; Kirschning, Carsten J.6; Langenkamp, Anja1,4; Falk, Christine7; Büning, Hildegard1,2; Rose‐John, Stefan8; Protzer, Ulrike*,4,5,§

1Center for Molecular Medicine Cologne (ZMMK), University Hospital Cologne, Köln, Germany

2Department of Internal Medicine I, University Hospital Cologne, Köln, Germany

3Department of Gastroenterology and Hepatology, University Hospital Cologne, Köln, Germany

4Institute for Medical Microbiology, Immunology and Hygiene, University Hospital Cologne, Köln, Germany

5Institute of Virology, Technische Universität München/Helmholtz Zentrum München, München, Germany

6Institute of Medical Microbiology, Immunology and Hygiene, Technische Universität München, München, Germany

7Immunomonitoring Unit, National Center for Tumor Diseases (NCT) / German Cancer Research Center (DKFZ) / Institute of Immunology, University Hospital Heidelberg, Heidelberg, Germany

8Department of Biochemistry, Christian‐Albrechts‐Universität zu Kiel, Medical Faculty, Kiel, Germany

Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Trogerstr. 30, D‐81675 München, Germany===

Received April 02, 2009

Accepted August 03, 2009