Biosynthesis (original) (raw)
Overview
Editors:
- Finian J. Leeper
- Department of Chemistry, University of Cambridge, Cambridge, Great Britain
- John C. Vederas
- Department of Chemistry, University of Alberta, Edmonton, Canada
This series presents critical reviews of the present position and future trends in modern chemical research
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About this book
This book is the second of two volumes that deal with discovery of chemical pathways of biosynthesis of natural products (secondary metabolites). The first volume covered the use of isotopes in biosynthetic research and the formation of enzyme cofactors and reduced polyketides. This second volume describes biosynthesis of aromatic (unreduced) polyketides, enzymes responsible for cyclization of terpenoids (isoprenoids), and biochemical generation of selected classes of alkaloids (prenylated tryptophan, tropane, pyrrolizidine). Knowledge of the pathways and the techniques to elucidate them opens the door to combinatorial biosynthesis as well as to the production of targeted pharmaceutical agents utilizing a combination of chemistry, molecular biology and protein biochemistry.
Keywords
Table of contents (5 chapters)
Editors and Affiliations
Department of Chemistry, University of Cambridge, Cambridge, Great Britain
Finian J. Leeper
Department of Chemistry, University of Alberta, Edmonton, Canada
John C. Vederas
Bibliographic Information
- Book Title: Biosynthesis
- Book Subtitle: Aromatic Polyketides, Isoprenoids, Alkaloids
- Editors: Finian J. Leeper, John C. Vederas
- Series Title: Topics in Current Chemistry
- DOI: https://doi.org/10.1007/3-540-48146-X
- Publisher: Springer Berlin, Heidelberg
- eBook Packages: Springer Book Archive
- Copyright Information: Springer-Verlag Berlin Heidelberg 2000
- Hardcover ISBN: 978-3-540-66573-1Published: 27 March 2000
- Softcover ISBN: 978-3-642-08583-3Published: 06 December 2010
- eBook ISBN: 978-3-540-48146-1Published: 01 July 2003
- Series ISSN: 0340-1022
- Series E-ISSN: 1436-5049
- Edition Number: 1
- Number of Pages: X, 247
- Topics: Biochemical Engineering, Organic Chemistry, Biochemistry, general