- Paget S: The distribution of secondary growths in cancer of the breast. Lancet 1: 571–573, 1889.
Google Scholar
- Ewing J: A treatise on tumors, 3rd edn. W.B. Saunders, Philadelphia, 1928.
Google Scholar
- Sugarbaker EV: Patterns of metastasis in human malignancies. In: Marchalonis JJ, Hanna MG, Fidler IJ (eds) Cancer biology reviews, Vol 2. Marcel Dekker, New York, 1980.
Google Scholar
- Lindberg R: Distribution of cervical lymph node metastases from squamous cell carcinoma of the upper respiratory and digestive tracts. Cancer 29: 1446–1449, 1972.
Google Scholar
- Weiss L, Haydock K, Pickren JW, Lane WW: Organ vascularity and metastatic frequency. Am J Pathol 101: 101–114, 1980.
Google Scholar
- Fidler IJ, Gersten DM, Hart IR: The biology of cancer invasion and metastasis. Adv Cancer Res 28: 149–250, 1978.
Google Scholar
- Fidler IJ: General considerations for studies of experimental cancer metastasis. In: Busch H (ed) Methods in cancer research, Vol XV. Academic Press, New York, 1978.
Google Scholar
- Wexler H: Accurate identification of experimental pulmonary metastases. J Natl Cancer Inst 36: 641–645, 1966.
Google Scholar
- Fidler IJ: Selection of successive tumour lines for metastasis. Nature (New Biol) 242: 148–149, 1973.
Google Scholar
- Becker FF: Patterns of spontaneous metastasis of transplantable hepatocellular carcinomas. Cancer Res 38: 163–167, 1978.
Google Scholar
- Van de Velde CJH, Van Putten LM, Zwaveling A: A new metastasizing mammary carcinoma model in mice: Model characteristics and applications. Eur J Cancer 13: 555–565, 1977.
Google Scholar
- Cloudman AM: Organophilic tendencies of two transplantable tumors of the mouse. Cancer Res 7: 585–591, 1947.
Google Scholar
- Pilgrim HI: The kinetics of the organ-specific metastasis of a transplantable reticuloendothelial tumor. Cancer Res 29: 1200–1205, 1969.
Google Scholar
- Parks RC: Organ-specific metastasis of a transplantable reticulum cell sarcoma. J Natl Cancer Inst 52: 971–973, 1974.
Google Scholar
- Greene HSN, Harvey EK: Relationship between the dissemination of tumor cells and the distribution of metastases. Cancer Res 24: 799–811, 1964.
Google Scholar
- Kerbel RS: Implications of immunological heterogeneity of tumours. Nature 280: 358–360, 1979.
Google Scholar
- Hart IR, Fidler IJ: The implications of tumor heterogeneity for studies on the biology and therapy of cancer metastasis. Biochim Biophys Acta 651: 37–50, 1981.
Google Scholar
- Fidler IJ, Kripke ML: Metastasis results from preexisting variant cells within a malignant tumor. Science 197: 893–895, 1977.
Google Scholar
- Kripke ML, Gruys E, Fidler IJ: Metastatic heterogeneity of cells from an ultraviolet light-induced murine sarcoma of recent origin. Cancer Res 36: 1962–1968, 1978.
Google Scholar
- Fidler IJ, Hart IR: The origin of metastatic heterogeneity in tumors. Eur J Cancer 17: 487–494, 1981.
Google Scholar
- Poste G, Fidler IJ: The pathogenesis of cancer metastasis. Nature 283: 139–143, 1979.
Google Scholar
- Brunson KW, Beattie G, Nicolson GL: Selection and altered properties of brain-colonizing metastatic melanoma. Nature 272: 543–545, 1978.
Google Scholar
- Tao T, Matter A, Vogel K, Burger MM: Liver-colonizing melanoma cells selected from B16 melanoma. Int J Cancer 23: 854–857, 1979.
Google Scholar
- Shearman PJ, Longenecker BM: Selection for virulence and organ-specific metastasis of herpes virus-transformed lymphoma cells. Int J Cancer 25: 363–369, 1980.
Google Scholar
- Brunson KW, Nicolson GL: Selection of malignant melanoma variant cell lines for ovary colonization. J Supramol Struct 11: 517–525, 1979.
Google Scholar
- Raz A, Hart IR: Murine melanoma: A model for intracranial metastasis. Br J Cancer 42: 331–341, 1980.
Google Scholar
- Nicolson GL, Brunson KW, Fidler IJ: Specificity of arrest, survival, growth of selected metastatic variant cell lines. Cancer Res 38: 4105–4111, 1978.
Google Scholar
- Proctor JW: Rat sarcoma model supports both ‘soil seed’ and ‘mechanical’ theories of metastatic spread. Br J Cancer 34: 651–654, 1976.
Google Scholar
- Griffiths JD, Salsbury AJ: The fate of circulating Walker 256 tumour cells injected intravenously into rats. Br J Cancer 17: 546–557, 1963.
Google Scholar
- Fidler IJ, Nicolson GL: Organ selectivity for implantation, survival and growth of B16 melanoma variant tumor lines. J Natl Cancer Inst 57: 1190–1202, 1976.
Google Scholar
- Fidler IJ, Gersten DM, Riggs CW: Relationship of host immune status to tumor cell arrest, distribution and survival in experimental metastasis. Cancer 40: 46–55, 1977.
Google Scholar
- Fisher B, Fisher ER: The organ distribution of disseminated 51Cr-labeled tumor cells. Cancer Res 27: 412–420, 1967.
Google Scholar
- Fisher B, Fisher ER: Barrier function of lymph node to tumor cells and erythrocytes. Cancer 20: 1907–1919, 1979.
Google Scholar
- Zeidman I, Buss JM: Transpulmonary passage of tumor cell emboli. Cancer Res 12: 731–738, 1952.
Google Scholar
- Sato H, Suzuki M: Deformability and viability of tumor cells by transcapillary passage with reference to organ affinity of metastasis in cancer. In: Weiss L (ed), Fundamental aspects of metastasis. North-Holland, Amsterdam, pp 311–317, 1976.
Google Scholar
- Zeidman I: The fate of circulating tumor cells. 1. Passage of cells through capillaries. Cancer Res 21: 38–39, 1961.
Google Scholar
- Wood S: Experimental studies of the intravascular dissemination of ascitic V2 carcinoma cells in the rabbit, with special reference to fibrinogen and fibrinolytic agents. Bull Schweiz Akad Med Wiss 20: 92–121, 1964.
Google Scholar
- Weiss L: Cancer cell traffic from the lungs to the liver. An example of metastatic inefficiency. Int J Cancer 25: 385–392, 1980.
Google Scholar
- Nicolson GL: Experimental tumor metastasis: Characteristics and organ specificity. BioScience 28: 441–447, 1978.
Google Scholar
- Roser B: The distribution of intravenously injected Kupffer cells in the mouse. J Reticuloendothel Soc 5: 455–471, 1968.
Google Scholar
- Gillette RW: Variation in the homing properties of 51Cr-labeled Thy antigen-positive lymphoma. Cell Immunol 51: 23–31, 1980.
Google Scholar
- Gillette RW, Fox A: Changes with age in the homing properties and mitogen responses of lymphocytes from normal and leukemia-prone mice. Cell Immunol 51: 32–41, 1980.
Google Scholar
- Nicolson GL, Winkelhake JL: Organ specificity of blood-borne tumour metastasis determined by cell adhesion. Nature 255: 230–232, 1975.
Google Scholar
- Schirrmacher V, Cheinsong-Popov R, Arnheiter H: Hepatocyte-tumor cell interaction in vitro. 1. Conditions for rosette formation and inhibition by anti-H-2-antibody. J Exp Med 151: 984–989, 1980.
Google Scholar
- Kahan B: Ovarian localization by embryonal teratocarcinoma cells derived from female germ cells. Somatic Cell Genet 5: 763–780, 1979.
Google Scholar
- Shearman PJ, Gallatin WM, Longenecker BM: Detection of a cell-surface antigen correlated with organ-specific metastasis. Nature 286: 267–269, 1980.
Google Scholar
- Nicolson GL: Cell surface proteins and glycoproteins of metastatic murine melanomas and sarcomas. In: Ruddon R (ed) Biological markers of neoplasia: basic and applied aspects. Elsevier North-Holland, Amsterdam, pp 227–239, 1978.
Google Scholar
- Sinha BK, Goldenberg GJ: The effect of trypsin and neuraminidase on the circulation and organ distribution of tumor cells. Cancer 34: 1956–1961, 1974.
Google Scholar
- Weiss L, Fisher B, Fisher ER: Observations on the effect of neuraminidase on the distribution of intravenously injected Walker tumor cells in rats. Cancer 34: 680–683, 1975.
Google Scholar
- Hagmar B, Ryd W: Tumor cell locomotion: A factor in metastasis formation. Influence of cytochalasin B on a tumor dissemination pattern. Int J Cancer 19: 576–580, 1977.
Google Scholar
- Hart IR, Raz A, Fidler IJ: Effect of cytoskeleton-disrupting agents on the metastatic behavior of melanoma cells. J Natl Cancer Inst 64: 891–900, 1980.
Google Scholar
- Poste G, Nicolson GL: Modification of the arrest of metastatic tumor cells in the microcirculation after treatment with plasma membrane vesicles from highly metastatic cells. Proc Natl Acad Sci USA 77: 399–403, 1980.
Google Scholar
- Fidler IJ, Nicolson GL: Fate of recirculating B16 melanoma metastatic variant cells in parabiotic syngeneic recipiens. J Natl Cancer Inst 58: 1867–1872, 1977.
Google Scholar
- Talmadge JE, Key M, Hart IR: Characterization of a murine ovarian reticulum cell sarcoma of histiocytic origin. Cancer Res 41: 1271–1280, 1981.
Google Scholar
- Hart IR, Talmadge JE, Fidler IJ: Metastatic behavior of a murine reticulum cell sarcoma exhibiting organ-specific growth. Cancer Res 41: 1281–1287, 1981.
Google Scholar
- Giavazzi R, Alessandri G, Spreafico F, Garattini S, Mantovani A: Metastasizing capacity of tumour cells from spontaneous metastases of transplanted murine tumours. Br J Cancer 42: 462–472, 1980.
Google Scholar
- Nicolson GL, Custead SE: Tumor metastasis is not due to adaptation of cells to a new organ environment. Science 215: 176–178, 1982.
Google Scholar
- Weissmann G, Bloomgarden D, Kaplan R, Cohen C, Hoffstein S, Collins T, Gotlieb A, Nagle D: A general method for the introduction of enzymes by means of immunoglobulin-coated liposomes into lysosomes of deficient cells. Proc Natl Acad Sci USA 72: 88–92, 1975.
Google Scholar
- Gregoriadis G, Buckland RA: Enzyme-containing liposomes alleviate a model for storage disease. Nature 244: 170–172, 1973.
Google Scholar
- Folkman J, Handenschild CC, Zetter BR: Long-term culture of capillary endothelial cells. Proc Natl Acad Sci USA 76: 5217–5221, 1979.
Google Scholar
- Kramer RH, Nicolson GL: Interactions of tumor cells with vascular endothelial cell monolayers: A model for metastatic invasion. Proc Natl Acad Sci USA 76: 5704–5708, 1979.
Google Scholar
- Kramer RH, Gonzalez R, Nicolson GL: Metastatic tumor cells adhere preferentially to the extracellular matrix underlying vascular endothelial cells. Int J Cancer 26: 639–645, 1980.
Google Scholar
- Murray JC, Liotta L, Rennard SI, Martin GR: Adhesion characteristics of murine metastatic and nonmetastatic tumor cells in vitro. Cancer Res 40: 347–351, 1980.
Google Scholar
- Nicolson GL, Irimura T, Gonzalez R, Ruoslahti E: The role of fibronectrin in adhesion of metastatic melanoma cells to endothelial cells and their basal lamina. Exp Cell Res 135: 461–465, 1981.
Google Scholar
- Terranova VP, Foltz C, Murray JC, Martin GR: Laminin as an attachment factor for metastatic cells (abstract). Proc Am Assoc Cancer Res 22: 55, 1981.
Google Scholar
- Poste G, Doll J, Hart IR, Fidler IJ: In vitro selection of murine B16 melanoma variants with enhanced tissue-invasive properties. Cancer Res 40: 1636–1644, 1980.
Google Scholar
- Warren BA: Environment of the blood-borne tumor embolus adherent to vessel wall. J Med 4: 150–177, 1973.
Google Scholar
- Kleinman HK, Klebe RJ, Martin GR: Role of collagenous matrices in the adhesion and growth of cells. J Cell Biol 88: 473–485, 1981.
Google Scholar
- Vlodavsky I, Gospodarowicz D, Respective roles of laminin and fibronectin in adhesion of human carcinoma and sarcoma cells. Nature 289: 304–307, 1981.
Google Scholar
- Terranova VP, Rohrbach DH, Martin GR: Role of laminin in the attachment of PAM 212 (epithelial cells) to basement membrane collagen. Cell 22: 719–726, 1980.
Google Scholar
- Giavazzi R, Liotta L, Hart IR: Laminin inhibits the adhesion of a murine tumor of macrophage origin. Exp Cell Res (in press).
- Albrechsten R, Nielsen M, Wever U, Engvall E, Ruoslahti E: Basement membrane changes in breast cancer detected by immunohistochemical staining for laminin. Cancer Res 41: 5076–5081, 1981.
Google Scholar
- Neri A, Ruoslahti E, Nicolson GL: Distribution of fibronectin on cloned cell lines of a rat mammary adenocarcinoma growing in vitro and in vivo at primary and metastatic sites. Cancer Res 41: 5082–5095, 1981.
Google Scholar
- Kinsey DL: An experimenal study of preferential metastasis. Cancer 13: 674–676, 1960.
Google Scholar
- Sugarbaker EV, Cohen AM, Ketcham AS: Do metastases metastasize? Ann Surg 174: 161–166, 1971.
Google Scholar
- Hart IR, Fidler IJ: Role of organ selectivity in the determination of metastatic patterns of B16 melanoma. Cancer Res 40: 2281–2287, 1980.
Google Scholar
- Fisher B, Fisher ER, Feduska N: Trauma and the localization of tumor cells. Cancer 20: 23–30, 1967.
Google Scholar
- Agostino D, Cliffton EE: Organ localization and the effect of trauma on the fate of circulating cancer cells. Cancer Res 25: 1728–1732, 1965.
Google Scholar
- Bellamy D, Hinsull SM: Influence of lodgement site on the proliferation of metastases of Walker 256 carcinoma in the rat. Br J Cancer 37: 81–85, 1978.
Google Scholar
- Klein K, Coetzee ML, Madhav R, Ove P: Inhibition of tritiated thymidine incorporation in cultured cells by rat kidney extract. J Natl Cancer Inst 62: 1557–1564, 1979.
Google Scholar
- Todaro GJ, Fryling C, DeLarco JE: Transforming growth factors produced by certain human tumor cells: Polypeptides that interact with epidermal growth factor receptors. Proc Natl Acad Sci USA 77: 5258–5262, 1980.
Google Scholar
- Gospodarowicz D, Greenburg G, Bialecki H, Zetter BR: Factors involved in the modulation of cell proliferation in vivo and in vitro: The role of fibroblast and epidermal growth factors in the proliferative response of mammalian cells. In Vitro 14: 85–118, 1978.
Google Scholar
- Reif A: Evidence for organ specificity of defenses against tumors. In: Waters H (ed) The handbook of cancer immunology, Vol 1. Gauland STPM, New York, pp 174–240, 1978.
Google Scholar
- Folkman J: Tumor angiogenesis. Adv Cancer Res 19: 331–358, 1974.
Google Scholar