Dynamic Brachytherapy of the Prostate Under Active Image Guidance (original) (raw)

Abstract

Image-guided brachytherapy is a promising treatment for early stage prostate cancer. Current research emphasizes methods for intraoperative optimized planning and precise implantation of radioactive seeds. Some new technologies for these purposes are described in this paper. A morphological template will overcome pubic arch interference and achieve better-optimized dose coverage under the real-time dynamic dosimetry technique. Auto-segmentation of the prostate anatomy has been implemented for clinical use to reduce operative time. Just-in-time planning and procedure tracking under active image guidance can now be performed in the operating room. Interactive planning and dynamic dosimetry can be achieved based on seed recognition in the live ultrasound images, which permit real-time replanning to eliminate under-dosage. As a result of these advances, prostate brachytherapy of the future will increasingly be practised as a precision procedure rather than an art form.

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References

  1. Roy, J. N., Wallner, K. E., Chiu-Tsao, S. T., Anderson, L. L., and Ling, C. C.: CT-based optimized planning for transperineal prostate planning with customized template. Int. J. Radiat. Oncol. Biol. Phys. 21 (1991) 483–489.
    Google Scholar
  2. Messing, E.M., Zhang, J.B., Rubens, D.J., Brasacchio, R.A., Strang, J.G., Soni, A., Okunieff, P.G. and Yu, Y.: Intraoperative optimized inverse planning for prostate brachytherapy: Early experience. Int. J. Radiat. Oncol. Biol. Phys. 44 (1999) 801–808.
    Article Google Scholar
  3. Arambula, C. F., Davies, B.L.: Automated prostate recognition: a key process for clinically effective robotic prostatectomy. Med Biol Eng Comput Mar. 37 (1999) 236-243.
    Google Scholar
  4. Kwoh, C. K., Teo, M. Y., Ng, W. S., Tan, S. N., Jones, L. M.: Outlining the prostate boundary using the harmonics method. Med Biol Eng Comput. 36 (1998) 768–771.
    Article Google Scholar
  5. Aarnink, R. G., Pathak, S. D., de la Rosette, J. J., Debruyne, F. M., Kim, Y., Wijkstra, H.: Edge detection in prostatic ultrasound images using integrated edge maps. Ultrasonics. 36 (1998) 635–642.
    Article Google Scholar
  6. Aarnink, R. G., Giesen, R. J., Huynen, A. L., de la Rosette, J. J., Debruyne, F. M., Wijkstra, H.: A practical clinical method for contour determination in ultrasonographic prostate images. Ultrasound Med Biol. 20 (1994) 705–717.
    Article Google Scholar
  7. Cheng, G., Liu, H., Rubens, D.J., Strang, J.G., Liao, L., Yu, Y., Brasacchio, R., Messing, E.: Automatic segmentation of prostate in transrectal ultrasound imaging. Radiology 218 (2001) 612.
    Google Scholar
  8. Yu, Y., Waterman, F.M., Suntharalingam, N., Schulsinger, A.: Limitations of the minimum peripheral dose as a parameter for dose specification in permanent 125I prostate implants. Int. J. Radiation Oncology Biol. Phys. 34 (1996) 717–725.
    Article Google Scholar
  9. Yu, Y. and Schell, M.C.: A genetic algorithm for the optimization of prostate implants. Med. Phys. 23 (1996) 2085–2091.
    Article Google Scholar
  10. Yu, Y.: Multiobjective decision theory for computational optimization in radiation therapy. Med. Phys. 24 (1997) 1445–1454.
    Article Google Scholar
  11. Yu, Y., Zhang, J. B., Brasacchio, R.A., Okunieff, P.G., Rubens, D.J., Strang, J.G., Soni, A., and Messing, E.M.: Automated treatment planning engine for prostate seed implant brachytherapy. Int. J. Radiat. Oncol. Biol. Phys. 43 (1999) 647–652.
    Article Google Scholar

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Authors and Affiliations

  1. Department of Radiation Oncology, University of Rochester, 601 Elmwood Avenue, Rochester, NY, 14642, USA
    Gang Cheng, Haisong Liu & Yan Yu
  2. Department of Radiology, University of Rochester, 601 Elmwood Avenue, Rochester, NY, 14642, USA
    Lydia Liao

Authors

  1. Gang Cheng
  2. Haisong Liu
  3. Lydia Liao
  4. Yan Yu

Editor information

Editors and Affiliations

  1. Image Sciences Institute, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands
    Wiro J. Niessen & Max A. Viergever &

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© 2001 Springer-Verlag Berlin Heidelberg

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Cheng, G., Liu, H., Liao, L., Yu, Y. (2001). Dynamic Brachytherapy of the Prostate Under Active Image Guidance. In: Niessen, W.J., Viergever, M.A. (eds) Medical Image Computing and Computer-Assisted Intervention – MICCAI 2001. MICCAI 2001. Lecture Notes in Computer Science, vol 2208. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-45468-3\_42

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