International Collaboration is Feasible in Trials for Rare Conditions: The EURAMOS Experience (original) (raw)

• Friedman MA, Carter SK. The therapy of osteogenic sarcoma: current status and thoughts for the future. J Surg Oncol. 1972;4:482-510.
  Article CAS PubMed Google Scholar
• Marcove RC, Mike V, Hajek JV, et al. Osteogenic sarcoma under the age of twenty-one. A review of one hundred and forty-five operative cases. J Bone Joint Surg [Am]. 1970;52:411-423.
  CAS Google Scholar
• Weinfeld MS, Dudley HR. Osteogenic sarcoma: a follow-up study of the ninety-four cases observed at the Massachusetts General Hospital from 1920 to 1960. J Bone Joint Surg [Am]. 1962;44A:269-276.
  Google Scholar
• Dahlin DC, Coventry MB. Osteogenic sarcoma. A study of six hundred cases. J Bone Joint Surg [Am]. 1967;49:101-110.
  CAS Google Scholar
• Ochs JJ, Freeman AI, Douglass HO, et al. cis-Dichlorodiammineplatinum (II) in advanced osteogenic sarcoma. Cancer Treat Rep. 1978;62:239-245.
  CAS PubMed Google Scholar
• Gasparini M, Rouesse J, van Oosterom A, et al. Phase II study of cisplatin in advanced osteogenic sarcoma. European Organization for Research on Treatment of Cancer: Soft Tissue and Bone Sarcoma Group. Cancer Treat Rep. 1985;69:211-213.
  CAS PubMed Google Scholar
• Baum ES, Gaynon P, Greenberg L, et al. Phase II trail cisplatin in refractory childhood cancer: Children’s Cancer Study Group Report. Cancer Treat Rep. 1981;65:815-822.
  CAS PubMed Google Scholar
• Pratt CB, Shanks EC. Doxorubicin in treatment of malignant solid tumors in children. Am J Dis Child. 1974;127:534-536.
  CAS PubMed Google Scholar
• Cortes EP, Holland JF, Wang JJ, et al. Amputation and adriamycin in primary osteosarcoma. N Engl J Med. 1974;291:998-1000.
  Article CAS PubMed Google Scholar
• Jaffe N, Frei E, Traggis D, et al. Adjuvant methotrexate and citrovorum-factor treatment of osteogenic sarcoma. N Engl J Med. 1974;291:994-997.
  Article CAS PubMed Google Scholar
• Pratt CB, Howarth C, Ransom JL, et al. High-dose methotrexate used alone and in combination for measurable primary or metastatic osteosarcoma. Cancer Treat Rep. 1980;64:11-20.
  CAS PubMed Google Scholar
• Pratt CB, Roberts D, Shanks EC, et al. Clinical trials and pharmacokinetics of intermittent high-dose methotrexate-”leucovorin rescue” for children with malignant tumors. Cancer Res. 1974;34:3326-3331.
  CAS PubMed Google Scholar
• Harris MB, Cantor AB, Goorin AM, et al. Treatment of osteosarcoma with ifosfamide: comparison of response in pediatric patients with recurrent disease with patients previously untreated− A Pediatric Oncology Group study. Med Pediatr Oncol. 1995;24:87-92.
  Article CAS PubMed Google Scholar
• Goorin AM, Harris MB, Bernstein M, et al. Phase II/III trial of etoposide and high-dose ifosfamide in newly diagnosed metastatic osteosarcoma: a pediatric oncology group trial. J Clin Oncol. 2002;20:426-433.
  Article CAS PubMed Google Scholar
• Pratt C, Shanks E, Hustu O, et al. Adjuvant multiple drug chemotherapy for osteosarcoma of the extremity. Cancer. 1977;39:51-57.
  Article CAS PubMed Google Scholar
• Pratt CB, Rivera G, Shanks E, et al. Combination chemotherapy for osteosarcoma. Cancer Treat Rep. 1978;62:251-257.
  CAS PubMed Google Scholar
• Sutow WW, Gehan EA, Dyment PG, et al. Multidrug adjuvant chemotherapy for osteosarcoma: interim report of the Southwest Oncology Group Studies. Cancer Treat Rep. 1978;62:265-269.
  CAS PubMed Google Scholar
• Sutow WW, Sullivan MP, Fernbach DJ, et al. Adjuvant chemotherapy in primary treatment of osteogenic sarcoma. A Southwest Oncology Group study. Cancer. 1975;36:1598-1602.
  Article CAS PubMed Google Scholar
• Goorin AM, Frei E III, Abelson HT. Adjuvant chemotherapy for osteosarcoma: a decade of experience. Surg Clin North Am. 1981;61:1379-1389.
  CAS PubMed Google Scholar
• Taylor WF, Ivins JC, Pritchard DJ, et al. Trends and variability in survival among patients with osteosarcoma: a 7-year update. Mayo Clin Proc. 1985;60:91-104.
  CAS PubMed Google Scholar
• Carter SK. Adjuvant chemotherapy in osteogenic sarcoma: the triumph that isn’t? J Clin Oncol. 1984;2:147-148.
  CAS PubMed Google Scholar
• Edmonson JH, Green SJ, Ivins JC, et al. A controlled pilot study of high-dose methotrexate as postsurgical adjuvant treatment for primary osteosarcoma. J Clin Oncol. 1984;2:152-156.
  CAS PubMed Google Scholar
• Eilber F, Giuliano A, Eckardt J, et al. Adjuvant chemotherapy for osteosarcoma: a randomized prospective trial. J Clin Oncol. 1987;5:21-26.
  CAS PubMed Google Scholar
• Link MP, Goorin AM, Miser AW, et al. The effect of adjuvant chemotherapy on relapse-free survival in patients with osteosarcoma of the extremity. N Engl J Med. 1986;314:1600-1606.
  Article CAS PubMed Google Scholar
• Rosen G, Marcove RC, Caparros B, et al. Primary osteogenic sarcoma: the rationale for preoperative chemotherapy and delayed surgery. Cancer. 1979;43:2163-2177.
  Article CAS PubMed Google Scholar
• Rosen G, Murphy ML, Huvos AG, et al. Chemotherapy, en bloc resection, and prosthetic bone replacement in the treatment of osteogenic sarcoma. Cancer. 1976;37:1-11.
  Article CAS PubMed Google Scholar
• Winkler K, Beron G, Delling G, et al. Neoadjuvant chemotherapy of osteosarcoma: results of a randomized cooperative trial (COSS-82) with salvage chemotherapy based on histological tumor response. J Clin Oncol. 1988;6:329-337.
  CAS PubMed Google Scholar
• Provisor AJ, Ettinger LJ, Nachman JB, et al. Treatment of nonmetastatic osteosarcoma of the extremity with preoperative and postoperative chemotherapy: a report from the Children’s Cancer Group. J Clin Oncol. 1997;15:76-84.
  CAS PubMed Google Scholar
• Bacci G, Picci P, Ruggieri P, et al. Primary chemotherapy and delayed surgery (neoadjuvant chemotherapy) for osteosarcoma of the extremities. The Istituto Rizzoli Experience in 127 patients treated preoperatively with intravenous methotrexate (high versus moderate doses) and intra-arterial cisplatin. Cancer. 1990;65:2539-2553.
  Article CAS PubMed Google Scholar
• Goorin AM, Schwartzentruber DJ, Devidas M, et al. Presurgical chemotherapy compared with immediate surgery and adjuvant chemotherapy for nonmetastatic osteosarcoma: Pediatric Oncology Group Study POG-8651. J Clin Oncol. 2003;21:1574-1580.
  Article CAS PubMed Google Scholar
• Bielack SS, Kempf-Bielack B, Delling G, et al. Prognostic factors in high-grade osteosarcoma of the extremities or trunk: an analysis of 1,702 patients treated on neoadjuvant cooperative osteosarcoma study group protocols. J Clin Oncol. 2002;20:776-790.
  Article PubMed Google Scholar
• Meyers PA, Schwartz CL, Krailo M, et al. Osteosarcoma: a randomized, prospective trial of the addition of ifosfamide and/or muramyl tripeptide to cisplatin, doxorubicin, and high-dose methotrexate. J Clin Oncol. 2005;23:2004-2011.
  Article CAS PubMed Google Scholar
• Lewis IJ, Nooij MA, Whelan J, et al. Improvement in histologic response but not survival in osteosarcoma patients treated with intensified chemotherapy: a randomized phase III trial of the European Osteosarcoma Intergroup. J Natl Cancer Inst. 2007;99:112-128.
  Article CAS PubMed Google Scholar
• Ferrari S, Smeland S, Mercuri M, et al. Neoadjuvant chemotherapy with high-dose Ifosfamide, high-dose methotrexate, cisplatin, and doxorubicin for patients with localized osteosarcoma of the extremity: a joint study by the Italian and Scandinavian Sarcoma Groups. J Clin Oncol. 2005;23:8845-8852.
  Article PubMed Google Scholar
• Rosen G, Caparros B, Huvos AG, et al. Preoperative chemotherapy for osteogenic sarcoma: selection of postoperative adjuvant chemotherapy based on the response of the primary tumor to preoperative chemotherapy. Cancer. 1982;49:1221-1230.
  Article CAS PubMed Google Scholar
• Meyers PA, Heller G, Healey J, et al. Chemotherapy for nonmetastatic osteogenic sarcoma: the Memorial Sloan-Kettering experience. J Clin Oncol. 1992;10:5-15. [see comments].
  CAS PubMed Google Scholar
• Meyers PA, Gorlick R, Heller G, et al. Intensification of preoperative chemotherapy for osteogenic sarcoma: results of the Memorial Sloan-Kettering (T12) protocol. J Clin Oncol. 1998;16:2452-2458.
  CAS PubMed Google Scholar
• Winkler K, Beron G, Kotz R, et al. Neoadjuvant chemotherapy for osteogenic sarcoma: results of a Cooperative German/Austrian study. J Clin Oncol. 1984;2:617-624.
  CAS PubMed Google Scholar
• Fuchs N, Bielack SS, Epler D, et al. Long-term results of the co-operative German-Austrian-Swiss osteosarcoma study group’s protocol COSS-86 of intensive multidrug chemotherapy and surgery for osteosarcoma of the limbs. Ann Oncol. 1998;9:893-899.
  Article CAS PubMed Google Scholar
• Jaffe N, Knapp J, Chuang VP, et al. Osteosarcoma: intra-arterial treatment of the primary tumor with cis-diammine-dichloroplatinum II (CDP). Angiographic, pathologic, and pharmacologic studies. Cancer. 1983;51:402-407.
  Article CAS PubMed Google Scholar
• Jaffe N, Robertson R, Ayala A, et al. Comparison of intra-arterial cis-diamminedichloroplatinum II with high-dose methotrexate and citrovorum factor rescue in the treatment of primary osteosarcoma. J Clin Oncol. 1985;3:1101-1104.
  CAS PubMed Google Scholar
• Winkler K, Bielack S, Delling G, et al. Effect of intra-arterial versus intravenous cisplatin in addition to systemic doxorubicin, high-dose methotrexate, and ifosfamide on histologic tumor response in osteosarcoma (study COSS-86). Cancer. 1990;66:1703-1710.
  Article CAS PubMed Google Scholar
• Souhami RL, Craft AW, Van der Eijken JW, et al. Randomised trial of two regimens of chemotherapy in operable osteosarcoma: a study of the European Osteosarcoma Intergroup. Lancet. 1997;350:911-917.
  Article CAS PubMed Google Scholar
• Bramwell VH, Burgers M, Sneath R, et al. A comparison of two short intensive adjuvant chemotherapy regimens in operable osteosarcoma of limbs in children and young adults: the first study of the European Osteosarcoma Intergroup. J Clin Oncol. 1992;10:1579-1591.
  CAS PubMed Google Scholar
• Bacci G, Ferrari S, Delepine N, et al. Predictive factors of histologic response to primary chemotherapy in osteosarcoma of the extremity: study of 272 patients preoperatively treated with high-dose methotrexate, doxorubicin, and cisplatin. J Clin Oncol. 1998;16:658-663.
  CAS PubMed Google Scholar
• Saeter G, Alvegard TA, Elomaa I, et al. Treatment of osteosarcoma of the extremities with the T-10 protocol, with emphasis on the effects of preoperative chemotherapy with single-agent high-dose methotrexate: a Scandinavian Sarcoma Group study. J Clin Oncol. 1991;9:1766-1775.
  CAS PubMed Google Scholar
• Smeland S, Muller C, Alvegard TA, et al. Scandinavian Sarcoma Group Osteosarcoma Study SSG VIII: prognostic factors for outcome and the role of replacement salvage chemotherapy for poor histological responders. Eur J Cancer. 2003;39:488-494.
  Article CAS PubMed Google Scholar
• Meyers PA, Schwartz CL, Krailo MD, et al. Osteosarcoma: the addition of muramyl tripeptide to chemotherapy improves overall survival – a report from the Children’s Oncology Group. J Clin Oncol. 2008;26:633-638.
  Article CAS PubMed Google Scholar
• Harris MB, Gieser P, Goorin AM, et al. Treatment of metastatic osteosarcoma at diagnosis: a Pediatric Oncology Group Study. J Clin Oncol. 1998;16:3641-3648.
  CAS PubMed Google Scholar
• Bacci G, Picci P, Ferrari S, et al. Primary chemotherapy and delayed surgery for nonmetastatic osteosarcoma of the extremities: results of 164 patients preoperatively treated with high doses of methotrexate followed by cisplatin and doxorubicin. Cancer. 1993;72:3227-3238.
  Article CAS PubMed Google Scholar
• Strander H, Einhorn S. Effect of human leukocyte interferon on the growth of human osteosarcoma cells in tissue culture. Int J Cancer. 1977;19:468-473.
  Article CAS PubMed Google Scholar
• Brosjo O, Bauer HC, Brostrom LA, et al. Influence of human alpha-interferon on four human osteosarcoma xenografts in nude mice. Cancer Res. 1985;45:5598-5602.
  CAS PubMed Google Scholar
• Bauer HC, Brosjo O, Strander H. Comparison of the growth inhibiting effect of natural and recombinant interferon-alpha on human osteosarcomas in nude mice. J Interferon Res. 1987;7:365-369.
  CAS PubMed Google Scholar
• Allen IE, Ross SD, Borden SP, et al. Meta-analysis to assess the efficacy of interferon-alpha in patients with follicular non-Hodgkin’s lymphoma. J Immunother. 2001;24:58-65.
  Article CAS PubMed Google Scholar
• Bjorkstrand B, Svensson H, Goldschmidt H, et al. Alpha-interferon maintenance treatment is associated with improved survival after high-dose treatment and autologous stem cell transplantation in patients with multiple myeloma: a retrospective registry study from the European Group for Blood and Marrow Transplantation (EBMT). Bone Marrow Transplant. 2001;27:511-515.
  Article CAS PubMed Google Scholar
• Strander H, Bauer HC, Brosjo O, et al. Long-term adjuvant interferon treatment of human osteosarcoma. A pilot study. Acta Oncol. 1995;34:877-880.
  Article CAS PubMed Google Scholar
• Bukowski R, Ernstoff MS, Gore ME, et al. Pegylated interferon alfa-2b treatment for patients with solid tumors: a phase I/II study. J Clin Oncol. 2002;20:3841-3849.
  Article CAS PubMed Google Scholar
• Bunn S, Kelly D, Murray KF. Safety, efficacy and pharmacokinetics of interferon alfa-2b and ribavirin in children with chronic hepatitis C. J Hepatol. 2000;32:763.
  Google Scholar
• Wozniakowska-Gesicka T, Wisniewska-Ligier M, Kups J, et al. Influence of interferon-alpha therapy on the count and function of T lymphocytes in children with chronic hepatitis C. Pol Merkur Lekarski. 2001;11:344-347.
  CAS PubMed Google Scholar
• Bhatia S, Landier W, Robison L. Late effects of childhood cancer therapy. In: DeVita V, Hellman S, Rosenberg S, eds. Progress in Oncology 2002. Sudbury: Jone and Barlett Publications; 2003:171-201.
  Google Scholar
• Hudson MM, Tyc VL, Cremer LK, et al. Patient satisfaction after limb-sparing surgery and amputation for pediatric malignant bone tumors. J Pediatr Oncol Nurs. 1998;15:60-69. discussion 70-71.
  CAS PubMed Google Scholar
• Nicholson HS, Mulvihill JJ, Byrne J. Late effects of therapy in adult survivors of osteosarcoma and Ewing’s sarcoma. Med Pediatr Oncol. 1992;20:6-12.
  Article CAS PubMed Google Scholar
• Postma A, Kingma A, De Ruiter JH, et al. Quality of life in bone tumor patients comparing limb salvage and amputation of the lower extremity. J Surg Oncol. 1992;51:47-51.
  Article CAS PubMed Google Scholar
• Weddington WW. Psychological outcomes in survivors of extremity sarcomas following amputation or limb-sparing surgery. Cancer Treat Res. 1991;56:53-60.
  CAS PubMed Google Scholar
• Calaminus G, Weinspach S, Teske C, et al. Quality of life in children and adolescents with cancer. First results of an evaluation of 49 patients with the PEDQOL questionnaire. Klin Padiatr. 2000;212:211-215.
  Article CAS PubMed Google Scholar
• Varni JW, Burwinkle TM, Katz ER, et al. The PedsQL in pediatric cancer: reliability and validity of the Pediatric Quality of Life Inventory Generic Core Scales, Multidimensional Fatigue Scale, and Cancer Module. Cancer. 2002;94:2090-2106.
  Article PubMed Google Scholar
• Nagarajan R, Neglia JP, Clohisy DR, et al. Limb salvage and amputation in survivors of pediatric lower-extremity bone tumors: what are the long-term implications? J Clin Oncol. 2002;20:4493-4501.
  Article PubMed Google Scholar
• Wilhelmsen L. Role of the Data and Safety Monitoring Committee (DSMC). Stat Med. 2002;21:2823-2829.
  Article PubMed Google Scholar
• DeMets DL, Yusuf S. The Data and Safety Monitoring Committee: some final thoughts. Am Heart J. 2001;141:548-549.
  Article CAS PubMed Google Scholar