Expression of The Kynurenine Pathway Enzymes in Human Microglia and Macrophages (original) (raw)
References
M.P. Heyes, K. Saito, S.P. Markey, Human macrophages convert L-tryptophan into the neurotoxin quinolinic acid_Biochem. J._283, 633–635 (1992). PubMedCAS Google Scholar
B.J. Brew, L. Pemberton, L. Evans, M. Heyes, Quinolinic acid production by macrophages infected with demented and non-demented isolates of HIV_Clin_. Neuropathol. 12, Sl (1993). Google Scholar
G.J. Guillemin, B.J. Brew, Implications of the kynurenine pathway and quinolinic acid in Alzheimer’s disease (review), Redox Rep. in press, (2002). Google Scholar
P. Guidetti, P. Hemachandra Reddy, D.A., Tagle, R. Schwarcz, Early kynurenergic impairment in Huntington’s Disease and in a transgenic animal model_Neurosci. Lett._283, 233–235 (2000). CAS Google Scholar
D.A. Bender, G.M. McCreanor, The preferred route of kynurenine metabolism in the rat_Biochitn. Biophys. Acta_717, 56–60 (1982). ArticleCAS Google Scholar
N.P. Botting, Chemistry and neurochemistry of the kynurenine pathway of tryptophan metabolism_Chem. Soc. Reviews_24, 401–412 (1995). ArticleCAS Google Scholar
G. Curzon, Brain tryptophan. Normal and disturbed_control_ _Adv.Exp.Med.Bio1.398_27–34 (1996). Article Google Scholar
F. Moroni, Tryptophan metabolism and brain function: focus on kynurenine and other indole metabolites [In Process Citation]_Eur. J. Pharmacol._375, 87–100 (1999). ArticlePubMedCAS Google Scholar
T.W. Stone, Neuropharmacology of quinolinic and kynurenic acids_Pharmacol. Rev._45, 309–379 (1993). PubMedCAS Google Scholar
I.P. Lapin, I.B. Prakhie, I.P. Kiseleva, Excitatory effects of kynurenine and its metabolites, amino acids and convulsants administered into brain ventricles: differences between rats and mice_J. Neural. Transm._54, 229–238 (1982). ArticlePubMedCAS Google Scholar
C.L. Eastman, Cytotoxicity of 3-hydroxykynurenine in a neuronal hybrid cell line_Brain Res._495, 225–231 (1989). ArticlePubMedCAS Google Scholar
G. Melillo, M.C. Bosco, T. Musso, L. Varesio, lmmunobiology of picolinic acid_Adv. Exp. Med. Biol._398, 135–141 (1996). ArticlePubMedCAS Google Scholar
R. Schwarcz, W.O. Jr. Whetsell, R.M. Mangano, Quinolinic acid: an endogenous metabolite that produces axon-sparing lesions in rat brain_Science_219, 316–318 (1983). ArticlePubMedCAS Google Scholar
M.P. Heyes, C.L. Achim, C.A. Wiley, E.O. Major, K. Saito, S.P. Markey, Human microglia convert Ltryptophan into the neurotoxin quinolinic acid_Biochem. J._320: 595–597 (1996). PubMedCAS Google Scholar
M.G. Espey, O.N. Chernyshev, J.J. Reinhard, M.A. Namboodiri, C.A. Colton, Activated human microglia produce the excitotoxin quinolinic acid_Neuroreport_8, 431–434 (1997). ArticlePubMedCAS Google Scholar
G.J. Guillemin, S.J. Kerr, G.A. Smythe, D.G. Smith, V. Kapoor, P.J. Armati, J. Croitoru, B.J. Brew, Kynurenine pathway metabolism in human astrocytes: a paradox for neuronal protection_J. Neurochem._78, 1–13 (2001). Article Google Scholar
D. Alberati-Giani, P. Ricciardi-Castagnoli, C. Kohler, A.M. Cesura, Regulation of the kynurenine metabolic pathway by interferon-gamma in murine cloned macrophages and microglial cells_J. Neurochem._66, 996–1004 (1996). ArticlePubMedCAS Google Scholar
D. Alberati-Giani, A.M. Cesura, Expression of the kynurenine enzymes in macrophages and microglial cells: regulation by immune modulat¨®rs_Amino Acids_14, 251–255 (1998). ArticlePubMedCAS Google Scholar
M.P. Heyes, K. Saito, C.Y. Chen, M.G. Proescholdt, T.S. Jr. Nowak, J. Li, K.E. Beagles, M.A. Proescholdt, M.A. Zito, K. Kawai, S.P. Markey, Species heterogeneity between gerbils and rats: quinolinate production by microglia and astrocytes and accumulations in response to ischemic brain injury and systemic immune activation_J Neurochem_69, 1519–1529 (1997). ArticlePubMedCAS Google Scholar
M.P. Heyes, C.Y. Chen, E.O. Major, K. Saito, Different kynurenine pathway enzymes limit quinolinic acid formation by various human cell types_Biochem. J._326, 351–356 (1997). PubMedCAS Google Scholar
L.A. Pemberton, S.J. Kerr, G. Smythe, B.J. Brew, Quinolinic acid production by macrophages stimulated with IFN-gamma, TNF-alpha, and IFN-alpha_J. interferon Cytokine Res._17, 589–595 (1997). ArticlePubMedCAS Google Scholar
C.U. Kloss, G.W. Kreutzberg, G. Raivich, Proliferation of ramified microglia on an astrocyte monolayer: char acterization of stimulatory and inhibitory cytokines_J. Neurosci. Res._49, 248–254 (1997). ArticlePubMedCAS Google Scholar
D. Giulian, T.J. Baker, Characterization of ameboid microglia isolated from developing mammalian brain_Journal of Neuroscience_6, 2163–2178 (1986). PubMedCAS Google Scholar
S.J. Kerr, P.J. Armati, L.A. Pemberton, G. Smythe, B. Tattam, B.J. Brew, Kynurenine pathway inhibition reduces toxicity of HIV-infected macrophages_Neurology_49, 1671–1681 (1997). ArticlePubMedCAS Google Scholar
G. Guillemin, F.D. Boussin, J. Croitoru, M. Franck-Duchenne, R. Le Grand, F. Lazarini, D. Dormont, Obtention and characterization of primary astrocyte and microglial cultures from adult monkey brains_J. Neurosci. Res._49, 576–591 (1997). ArticlePubMedCAS Google Scholar
G.A. Smythe, S.J. Kerr, G.J. Guillemin, B. J. Brew, Quantification of picolinic acid using electron capture negative ion mass spectrometry_Anal. Biochem._submitted, (1998). Google Scholar
F. Villinger, D. Hunt, A. Mayne, M. Vuchetiv, H. Findley, and A.A. Ansari, Qualitative and quantitative studies of cytokines synthetized and secreted by non-human primate peripheral blood mononuclear cells_Cytokine_5. 169–179 (1993). Article Google Scholar
A.L. Cunningham, H. Naif, N. Saksena, G. Lynch, J. Chang, S. Li, R. Jozwiak, M. Alali, B. Wang, W. Fear, A. Sloane, L. Pemberton, 13. Brew, HIV infection of macrophages and pathogenesis of AIDS dementia complex: interaction of the host cell and viral genotype_J. Leukoc. Biol._62, 117–125 (1997). PubMedCAS Google Scholar
F. Du, W. Schmidt, E. Okuno, R. Kido, C. Kohler, R. Schwarcz, Localization of kynurenine aminotransferase immunoreactivity in the rat hippocampus_J_ Comp _Neurol_321, 477–487 (1992). CAS Google Scholar
M. Tamburin, M. Mostardini, L. Benatti, Kynurenine aminotransferase I (KATI) isoform gene expression in the rat brain: an in situ hybridization study_Neuroreport_10, 61–65 (1999). ArticlePubMedCAS Google Scholar
R. Kapoor, E. Okuno, R. Kido, V. Kapoor, Immuno-localization of kynurenine aminotransferase (KAT) in the rat medulla and spinal cord_Neuroreport_8, 3619–3623 (1997). ArticlePubMedCAS Google Scholar
J. Urenjak, Obrenovitch, Neuroprotective potency of kynurenic acid against excitotoxicity_Ne T.P.uroreport_11, 1341–1344 (2000). CAS Google Scholar