The World of Resveratrol (original) (raw)

• Siemann EH, Creasy LL. Concentration of the phytoalexin resveratrol in wine. Am J Enol Vitic 1992; 43:49–52.
  CAS Google Scholar
• Soleas GJ, Diamandis EP, Goldberg DM. Resveratrol: A molecule whose time has come? And gone? Clin Biochem 1997; 30:91–113.
  Article PubMed CAS Google Scholar
• Daniel O, Meier MS, Schlatter J, Frischknecht P. Selected phenolic compounds in cultivated plants: Ecologic functions, health implications, and modulation of pesticides. Environ Health Perspect 1999; 107 Suppl 1:109–114.
  Article PubMed CAS Google Scholar
• Constant J. Alcohol, ischemic heart disease, and the French paradox. Coron Artery Dis 1997; 8:645–649.
  Article PubMed CAS Google Scholar
• Ross R. Atherosclerosis - An inflammatory disease. N Engl J Med 1999; 340:115–126.
  Article PubMed CAS Google Scholar
• Nicholson AC, Najjar DP. Herpesviruses in atherosclerosis and thrombosis: etiologic agents or ubiquitous bystanders? Arterioscler Thromb Vasc Biol 1998; 18:339–348.
  Article PubMed CAS Google Scholar
• Jang M, Cai L, Udeani GO et al. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science 1997; 275:218–220.
  Article PubMed CAS Google Scholar
• Subbaramaiah K, Chung WJ, Michaluart P et al. Resveratrol inhibits cyclooxygenase-2 transcription and activity in phorbol ester-treated human mammary epithelial cells. J Bic J Chem 1998; 273:21875–21882.
  Article CAS Google Scholar
• Jang M, Pezzuto JM. Effects of resveratrol on 12-O-tetradecanoylphorbol-13acetate-induced oxidative events and gene expression in mouse skin. Cancer Lett 1998; 134:81–89.
  Article PubMed CAS Google Scholar
• Jong M, Pezzuto JM. Cancer chemopreventive activity of resveratrol. Drugs Exp Clin Res 1999; 25:65–77.
  Google Scholar
• Mizutani K, Ikeda K, Kawai Y, Yamori Y. Resveratrol stimulates the proliferation and differentiation of osteoblastic MC3T3–E1 cells. Biochem Biophys Res Commun 1998; 253:859–863.
  Article PubMed CAS Google Scholar
• Johnson JL, Maddipati KR. Paradoxical effects of resveratrol on the two prostaglandin H synthases. Prostaglandins Other Lipid Mediat 1998;56:131–143.
  Article PubMed CAS Google Scholar
• Lee SH, Shin NH, Kang SH et al. Alpha-viniferin: a prostaglandin H2 synthase inhibitor from root of Carex humilis. Planta Med 1998; 64:204–207.
  Article PubMed CAS Google Scholar
• Shin NH, Ryu SY, Lee H, Min KR, Kim Y. Inhibitory effects of hydroxystilbenes on cyclooxygenase from sheep seminal vesicles. Planta Med 1998; 64:283–284.
  Article PubMed CAS Google Scholar
• Knight J, Taylor GW, Wright P, Clare AS, Rowley AF. Eicosanoid biosynthesis in an advanced deuterostomate invertebrate, the sea squirt (Ciona intestinalis). Biochim Biophys Acta 1999; 1436:467–478.
  Article PubMed CAS Google Scholar
• Kawada N, Seki S, Inoue M, Kuroki T. Effect of antioxidants, resveratrol, quercetin, and N-acetylcysteine, on the functions of cultured rat hepatic stellate cells and Kupffer cells. Hepatology 1998; 27:1265–1274.
  Article PubMed CAS Google Scholar
• Chen T, Li J, Cao J, Xu Q, Komatsu K, Namba T. A new flavanone isolated from rhizoma smilacis glabrae and the structural requirements of its derivatives for preventing immunological hepatocyte damage. Planta Med 1999; 65:56–59.
  Article PubMed CAS Google Scholar
• Kimura Y, Okuda H, Arichi S. Effects of stilbenes on arachidonate metabolism in leukocytes. Biochim Biophys Acta 1985; 834:275–278.
  Article PubMed CAS Google Scholar
• Goldberg DM, Soleas GJ, Hahn SE, Diamandis EP, Karumanchiri A. Identification and assay of trihydroxystilbenes in wine and their biological properties. In: Watkins T, ed. Wine composition and health benefits. American Chemical Society, Washington DC, 1997; pp. 24–43.
  Google Scholar
• Kimura Y, Okuda H, Kubo M. Effects of stilbenes isolated from medicinal plants on arachidonate metabolism and degranulation in human polymorphonuclear leukocytes. J Ethnopharmacol 1995; 45:131–139.
  Article PubMed CAS Google Scholar
• Shan CW. Effects of polydatin on platelet aggregation of rabbits. Acta Pharmacol Sin 1988; 23:394–396.
  CAS Google Scholar
• Shan CW, Yang SQ, He HD, Shao SL, Zhang PW. Influences of 3,4,5-trihydroxy stilbene-3-J -mono-D-glucoside on rabbits’ platelet aggregation and thromboxane B2 production in vitro. Acta Pharmacol Sin 1990; 11:527–530.
  CAS Google Scholar
• Chung M-I, Teng C-M, Cheng K-L, Ko F-N, Lin C-N. An antiplatelet principle of Veratrum formosanum. Planta Med 1992; 58:274–276.
  Article PubMed CAS Google Scholar
• Pace-Asciak CR, Hahn S, Diamandis EP, Soleas G, Goldberg DM. The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: Implications for protection against coronary heart disease. Clin Chim Acta 1995; 235:207–219.
  Article PubMed CAS Google Scholar
• Bertelli AAE, Giovannini L, Gianncssi D. et al. Antiplatelet activity of synthetic and natural resveratrol in red wine. Int J Tiss React 1995; 17:1–3.
  CAS Google Scholar
• Bertelli AAE, Giovannini L, De Caterina R. et al. Antiplatelet activity of cis resveratrol. Drugs Exp Clin Res 1996; 22:61–63.
  PubMed CAS Google Scholar
• Orsini F, Pelizzoni F, Verotta L, Aburjai T, Rogers CB. Isolation, synthesis, and antiplatelet aggregation activity of resveratrol 3-O-beta-D-glucopyranoside and related compounds. J Nat Prod 1997; 60:1082–1087.
  Article PubMed CAS Google Scholar
• Cavenagh JD, Cahill MR, Kelsey SM. Adhesion molecules in clinical medicine. Crit Rev Clin Lab Sci 1998; 34:415–459.
  Article Google Scholar
• Chia MC. The role of adhesion molecules in atherosclerosis. Crit Rev Clin Lab Sci 1998; 35:573–602.
  Article PubMed CAS Google Scholar
• Ferrero ME, Bertelli AE, Fulgenzi A. et al. Activity in vitro of resveratrol on granulocyte and monocyte adhesion to endothelium. Am J Clin Nutr 1998; 68:1208–1214.
  PubMed CAS Google Scholar
• Rotondo S, Rajtar G, Manarini S et al. Effect of trans-resveratrol, a natural polyphenolic compound, on human polymorphonuclear leukocyte function. Br J Pharmacol 1998; 123:1691–1699.
  Article PubMed CAS Google Scholar
• Cheong H, Ryu SY, Kim KM. Anti-allergic action of resveratrol and related hydroxystilbenes. Planta Med 1999; 65:266–268.
  Article PubMed CAS Google Scholar
• Tsai SH, Lin-Shiau SY, Lin JK. Suppression of nitric oxide synthase and the down-regulation of the activation of NfkappaB in macrophages by resveratrol. Br J Pharmacol 1999; 126:673–680.
  Article PubMed CAS Google Scholar
• Wadsworth TL, Koop DR. Effects of the wine polyphenolics quercetin and resveratrol on pro-inflammatory cytokine expression in RAW 264.7 macrophages. Biochem Pharmacol 1999; 57:941–949.
  Article PubMed CAS Google Scholar
• Draczynska-Lusiak B, Chen YM, Sun AY. Oxidized lipoproteins activate NFkappaB binding activity and apoptosis in PC12 cells. Neuroreport 1998; 9:527–532.
  Article PubMed CAS Google Scholar
• Pendurthi UR, Williams JT, Rao LV. Resveratrol, a polyphenolic compound found in wine, inhibits tissue factor expression in vascular cells: A possible mechanism for the cardiovascular benefits associated with moderte consumption of wine. Arerioscler Thromb Vase Biol 1999; 19:419–426.
  Article CAS Google Scholar
• Casper RF, Quesne M, Rogers IM et al. Resveratrol has antagonist activity on the aryl hydrocarbon receptor: Implications for prevention of dioxin toxicity. Mol Pharmacol 1999; In Press.
  Google Scholar
• Arichi H, Kimura Y, Okuda H, Baba K, Kozawa M, Arichi S. Effects of stilbene components of the roots of Polygonum cuspidatum Sieb. et Zucc. on lipid metabolism. Chem Pharm Bull 1982; 30:1766–1770.
  Article PubMed CAS Google Scholar
• Goldberg DM, Hahn SE, Parkes, JG. Beyond alcohol: Beverage consumption and cardiovascular mortality. Clin Chim Acta 1995; 237:155–187.
  Article PubMed CAS Google Scholar
• Goldberg DM, Garovic-Kocic V, Diamandis EP, Pace-Asciak, CR. Wine: does the colour count? Clin Chim Acta 1996; 246:183–193.
  Article PubMed CAS Google Scholar
• Turrens JF, Lariccia J, Nair MG. Resveratrol has no effect on lipoprotein profile and does not prevent peroxidation of serum lipids in normal rats. Free Radic Res 1997; 27:557–62.
  Article PubMed CAS Google Scholar
• Wilson T, Knight Ti, Beitz DC, Lewis DS, Engen RL. Resveratrol promotes atherosclerosis in hypercholesterolemic rabbits. Life Sci 1996; 59:15–21.
  Article Google Scholar
• Uenobe F, Nakamura S-I, Miyazawa M. Antimutagenic effect of resveratrol against Trp-P-1. Mutat Res 1997; 373:197–200.
  Article PubMed CAS Google Scholar
• Mgbonyebi OP, Russo J, Russo IH. Antiproliferative effect of synthetic resveratrol on human breast epithelial cells. Int J Oncol 1998; 12:865–869.
  PubMed CAS Google Scholar
• ElAttar TM, Virji AS. Modulating effect of resveratrol and quercetin on oral cancer cell growth and proliferation. Anticancer Drugs 1999; 10:187–193.
  Article PubMed CAS Google Scholar
• Hsieh TC, Wu JM. Differential effects on growth, cell cycle arrest, and induction of apoptosis by resveratrol in human prostate cancer cell lines. Exp Cell Res 1999; 249:109–115.
  Article PubMed CAS Google Scholar
• Carbo N, Costelli P, Baccino FM, Lopez-Soriano FJ, Argiles JM. Resveratrol, a natural product present in wine, decreases tumour growth in a rat tumour model. Biochem Biophys Res Commun 1999; 254:739–743.
  Article PubMed CAS Google Scholar
• Clement MV, Hirpara JL, Chawdhury SH, Pervaiz S. Chemopreventive agent resveratrol, a natural product derived from grapes, triggers CD95 signaling-dependent apoptosis in human tumor cells. Blood 1998; 92:996–1002.
  PubMed CAS Google Scholar
• Huang C, Ma MY, Goranson A, Dong Z. Resveratrol suppresses cell transformation and induces apoptosis through a p53-dependent pathway. Carcinogenesis 1999; 20:237–242.
  Article PubMed CAS Google Scholar
• Ragione FD, Cucciolla V, Borriello A et al. Resveratrol arrests the cell division cycle at S/G2 phase transition. Biochem Biophys Res Commun 1998; 250:53–58.
  Article PubMed CAS Google Scholar
• Fontecave M, Lepoivre M, Elleingand E, Gerez C, Guittet O. Resveratrol, a remarkable inhibitor of ribonucleotide reductase. FEBS Lett 1998; 421:277–279.
  Article PubMed CAS Google Scholar
• Sun NJ, Woo SH, Cassady JM, Snapka RM. DNA polymerase and topoisomerase II inhibitors from Psoralea corylifolia. J Nat Prod 1998; 61:362–366.
  Article PubMed CAS Google Scholar
• Fukuhara K, Miyata N. Resveratrol as a new type of DNA-cleaving agent. Bioorg Med Chem Lett 1998; 8:3187–3192.
  Article PubMed CAS Google Scholar
• Ciolino HP, Daschner PJ, Yeh GC. Resveratrol inhibits transcription of CYPIA1 in vitro by preventing activation of the aryl hydrocarbon receptor. Cancer Res 1998; 58:5707–5712.
  PubMed CAS Google Scholar
• Teel RW, Huynh H. Modulation by phytochemicals of cytochrome P450-linked enzyme activity. Cancer Lett 1998; 133:135–141.
  Article PubMed CAS Google Scholar
• Frotschl R, Chichmanov L, Kleeberg U, Hildebrandt AG, Roots I, Brockmoller J. Prediction of aryl hydrocarbon receptor-mediated enzyme induction of drugs and chemicals by mRNA quantification. Chem Res Toxicol 1998; 11:1447–1452.
  Article PubMed CAS Google Scholar
• Frankel EN, Waterhouse AL, Kinsella JE. Inhibition of human LDL oxidation by resveratrol. Lancet 1993; 341.1103–1104.
  Article PubMed CAS Google Scholar
• Frankel EN, Waterhouse AL, Teissedre PL. Principal phenolic phytochemicals in selected California wines and their antioxidant activity in inhibiting oxidation of human low-density lipoproteins. J Agric Food Chem 1995; 43:890–894.
  Article CAS Google Scholar
• Soleas GJ, Tomlinson G, Diamandis EP, Goldberg, DM. Relative contributions of polyphenolic constituents to the antioxidant status of wines: Development of a predictive model. J Agric Food Chem 1997; 45:3995–4003.
  Article CAS Google Scholar
• Belguendouz L, Fremont L, Linard A. Resveratrol inhibits metal ion-dependent and independent peroxidation of porcine low-density lipoproteins. Biochem Pharmacol 1997; 53:1347–1355.
  Article PubMed CAS Google Scholar
• Fremont L, Belguendouz L, Delpal S. Antioxidant activity of resveratrol and alcohol-free wine polyphenols related to LDL oxidation and polyunsaturated fatty acids. Life Sci 1999; 64:2511–2521.
  Article PubMed CAS Google Scholar
• Belguendouz L, Fremont L, Gozzelino MT. Interaction of trans-resveratrol with plasma lipoproteins. Biochem Pharmacol 1998; 55:811–816.
  Article PubMed CAS Google Scholar
• Fauconneau B, Waffo-Teguo P, Huguet F, Barrier L, Decendit A, Merillon JM. Comparative study of radical scavenger and antioxidant properties of phenolic compounds from Vitis vinifera cell cultures using in vitro tests. Life Sci 1997; 61:2103–2110.
  Article PubMed CAS Google Scholar
• Chanvitayapongs S, Draczynska-Lusiak B, Sun AY. Amelioration of oxidative stress by antioxidants and resveratrol in PC12 cells. Neuroreport 1997; 8:1499–1502.
  Article PubMed CAS Google Scholar
• Draczynska-Lusiak B, Doung A, Sun AY. Oxidized lipoproteins may play a role in neuronal cell death in Alzheimer disease. Mol Chem Neuropathol 1998; 33:139–148.
  Article PubMed CAS Google Scholar
• Jang DS, Kang BS, Ryu SY, Chang 1M, Min KR, Kim Y. Inhibitory effects of resveratrol analogs on unopsonized zymosan-induced oxygen radical production. Biochem Pharmacol 1999; 57:705–712.
  Article PubMed CAS Google Scholar
• Waffo-Teguo P, Fauconneau B, Deffieux G, Huguet F, Vercauteren J, Merillon JM. Isolation, identification, and antioxidant activity of three stilbene glucosides newly extracted from vitis vinifera cell cultures. J Nat Prod 1998; 61:655–657.
  Article PubMed Google Scholar
• Shin NH, Ryu SY, Choi EJ, et al. Oxyresvcratrol as the potent inhibitor on dopa oxidase activity of mushroom tyrosinase. Biochem Biophys Res Commun 1998; 243:801–803.
  Article PubMed CAS Google Scholar
• Fitzpatrick DF, Hirschfield SL, Coffey RG. Endothelium-dependent vasorelaxing activity of wine and other grape products. Am J Physiol 1993; 265:H774–H778.
  PubMed CAS Google Scholar
• Chen CK, Pace-Asciak CR. Vasorelaxing activity of resveratrol and quercetin in isolated rat aorta. Gen Pharmacol 1996; 27:363–366.
  Article PubMed CAS Google Scholar
• Jager U, Nguyen-Duong H. Relaxant effect of trans-resveratrol on isolated porcine coronary arteries. Arzneimittelforschung 1999; 49:207–211.
  PubMed CAS Google Scholar
• Mellanen P, Petanen T, Lehtimaki J, et al. Wood-derived estrogens: studies in vitro with breast cancer cell lines and in vivo in trout. Toxicol Appl Pharmacol 1996; 136:381–388.
  Article PubMed CAS Google Scholar
• Gehm BD, McAndrews JM, Chien PY, Jameson JL. Resveratrol, a polyphenolic compound found in grapes and wine, is an agonist for the estrogen receptor. Proc Natl Acad Sci USA 1997; 94:14138–14143.
  Article PubMed CAS Google Scholar
• Stahl S, Chun TY, Gray WG. Phytoestrogens act as estrogen agonists in an estrogen-responsive pituitary cell line. Toxicol Appl Pharmacol 1998; 152:41–48.
  Article PubMed CAS Google Scholar
• Lu R, Serrero G. Resveratrol, a natural product derived from grape, exhibits antiestrogenic activity and inhibits the growth of human breast cancer cells. J Cell Physiol 1999; 179:297–304.
  Article PubMed CAS Google Scholar
• Kopp P. Resveratrol, a phytoestrogen found in red wine. A possible explanation for the conundrum of the `French paradox’? Eur J Endocrinol 1998; 138:619–620.
  Article Google Scholar
• Ashby J, Tinwell H, Pennie W, et al. Partial and weak oestrogenicity of the red wine constituent resveratrol: consideration of its superagonist aactivity in MCF-7 cells and its suggested cardiovascular protective effects. J Appl Toxicol 1999; 19:39–45.
  Article PubMed CAS Google Scholar
• Turner RT, Evans GL, Zhang M, Maran A, Sibonga JD. Is resveratrol an estrogen agonist in growing rats? Endocrinology 1999; 140:50–54.
  Article PubMed CAS Google Scholar
• Tham L, Goldberg DM, Diamandis P, Karumanchiri A, Soleas GJ. Extraction of resveratrol from human blood. Clin Biochem 1995; 28:339 (Abst).
  Google Scholar
• Goldberg DM, Tham L, Diamandis EP, Karumanchiri A, Soleas GJ. The assay of resveratrol and its distribution in human blood. Clin Chem 1995; 41:S115 (Abst).
  Google Scholar
• Blache D, Rustan I, Durand P, Lesgards G, Loreau N. Gas chromatographic analysis of resveratrol in plasma, lipoproteins and cells after in vitro incubations. J Chromatogr B Biomed Sci Appl 1997; 702:103–110.
  Article PubMed CAS Google Scholar
• Juan ME, Lamuela-Raventos RM, de la Torre-Boronat MC, Planas JM. Determination of trans-resveratrol in plasma by HPLC. Anal Chem 1999; 71:747750.
  Google Scholar
• Zhu Z, Klironomos G, Vachereau A, Neirinck L, Goodman DW. Determination of trans-resveratrol in human plasma by high-performance liquid chromatography. J Chromatogr B Biomed Sci Appl 1999; 724:389–392.
  Article PubMed CAS Google Scholar
• Bertelli AA, Giovannini L, Stradi R, Bertelli A, Tillement JP. Plasma, urine and tissue levels of trans-and cis-resveratrol (3,4’,5-trihydroxystilbene) after short-term or prolonged administration of red wine to rats. Int J Tissue React 1996; 18:67–71.
  PubMed CAS Google Scholar
• Bertelli AA, Giovannini L, Stradi R, Urien S, Tillement JP, Bertelli A. Kinetics of trans-and cis-resveratrol (3,4’,5-trihydroxystilbene) after red wine oral administration in rats. Int J Clin Pharmacol Res 1996; 16:77–81.
  PubMed CAS Google Scholar
• Bertelli A, Bertelli AA, Gozzini A, Giovannini L. Plasma and tissue resveratrol concentrations and pharmacological activity. Drugs Exp Clin Res 1998; 24:133–138.
  PubMed CAS Google Scholar
• Orsini F, Pelizzoni F, Bellini B, Miglierini G. Synthesis of biologically active polyphenolic glycosides (combretastatin and resveratrol series). Carbohydr Res 1997; 301:95–109.
  Article PubMed CAS Google Scholar
• Cichewicz RH, Kouzi SA. Biotransformation of resveratrol to piceid by Bacillus cereus. J Nat Prod 1998; 61:1313–1314.
  Article PubMed CAS Google Scholar
• Bertelli AA, Gozzini A, Stradi R, Stella S, Bertelli A. Stability of resveratrol over time and in the various stages of grape transformation. Drugs Exp Clin Res 1998; 24:207–211.
  PubMed CAS Google Scholar
• Busam G, Junghanns KT, Kneusel RE, Kassemeyer HH, Matern U. Characterization and expression of caffeoyl-coenzyme A 3–0-methyltransferase proposed for the induced resistance response of Vitis vinifera L. Plant Physiol 1997; 115:1039–1048.
  Article PubMed CAS Google Scholar
• Miloso M, Bertelli AA, Nicolini G, Tredici G. Resveratrol-induced activation of the mitogen-activated protein kinases, ERK1 and ERK2, in human neuroblastoma SHSY5Y cells. Neurosci Lett 1999; 264:141–144.
  Article PubMed CAS Google Scholar