Craniofacial Development The Tissue and Molecular Interactions That Control Development of the Head (original) (raw)

Overview

Authors:

• L. Robson 1,
• Darell J. R. Evans 2

1. P. H. Francis-West
   1. Department of Craniofacial Development, King’s College, London, UK
2. L. Robson
   1. Department of Neuroscience Bart’s and The London, Queen Mary’s School of Medicine and Dentistry, London, UK
3. Darell J. R. Evans
   1. School of Biosciences, Cardiff University, Cardiff, UK

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About this book

Craniofacial development is a multistep and intricate process initially involving a number of inductive interactions that control neural and neural crest development, which are followed by a series of epithelial-mesenchymal interactions that control outgrowth, patterning, and skeletal differentiation. Certain aspects of craniofacial development are unique developmental processes in higher vertebrates. First, in higher vertebrates the cranial neural crest, in contrast to the trunk neural crest, gives rise to the skeletal structures. These skeletal elements include those comprising mem­ brane bone and secondary cartilage, which with the exception of the clavicle are tissue types found exclusively in the head in higher vertebrates. Second, with the exception of the tongue, the origin of the musculature is distinct from other regions of the body. The body and tongue muscles are formed from the segmented epithelial somites whilst the head musculature is formed from unsegmented paraxial and prechordal mesoderm. Furthermore, the signalling cascades that control myogenic differentia­ tion appear to be distinct as determined by gene expression and the response of myogenic cells to growth factors. Finally, the neurogenic placodes, which give rise to the sensory organs and some cranial ganglia, are only found in the head. Over recent years, there have been significant advances in our knowledge of the molecular proc­ esses that control craniofacial development in a number of animal models. This has given insight into the genes that control many aspects of head development from the initial induction of the head to the final stages of differentiation.

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Table of contents (9 chapters)

1. Introduction

   • P. H. Francis-West, L. Robson, Darell J. R. Evans
     Pages 1-1

2. Summary

   • P. H. Francis-West, L. Robson, Darell J. R. Evans
     Pages 99-99

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Authors and Affiliations

• Department of Craniofacial Development, King’s College, London, UK

P. H. Francis-West

• Department of Neuroscience Bart’s and The London, Queen Mary’s School of Medicine and Dentistry, London, UK

L. Robson

• School of Biosciences, Cardiff University, Cardiff, UK

Darell J. R. Evans

Bibliographic Information

• Book Title: Craniofacial Development The Tissue and Molecular Interactions That Control Development of the Head
• Authors: P. H. Francis-West, L. Robson, Darell J. R. Evans
• Series Title: Advances in Anatomy, Embryology and Cell Biology
• DOI: https://doi.org/10.1007/978-3-642-55570-1
• Publisher: Springer Berlin, Heidelberg
• eBook Packages: Springer Book Archive
• Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 2003
• Softcover ISBN: 978-3-540-00363-2Published: 15 April 2003
• eBook ISBN: 978-3-642-55570-1Published: 06 December 2012
• Series ISSN: 0301-5556
• Series E-ISSN: 2192-7065
• Edition Number: 1
• Number of Pages: VI, 144
• Topics: Developmental Biology

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