Innate Immune Responses to LCMV Infections: Natural Killer Cells and Cytokines (original) (raw)
Bauer S, Groh V, Wu J, Steinle A, Phillips JH, Lanier LL, Spies T (1999) Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. Science 285:727-729 ArticlePubMedCAS Google Scholar
Biron CA (1999) Initial and innate responses to viral infections-pattern setting in immunity or disease. Curr Opin Microbiol 2:374–381 ArticlePubMedCAS Google Scholar
Biron CA, Nguyen KB, Pien GC, Cousens LP, Salazar-Mather TP (1999) Natural killer cells in antiviral defense: function and regulation by innate cytokines. Annu Rev Immunol 17: 189–220 ArticlePubMedCAS Google Scholar
Biron CA, Sen GC (2001) Interferons and other cytokines. In: Knipe D, Howley P, Griffin D, Lamb R, Martin M, Straus S (eds) Fields Virology. Lippincott, Williams & Wilkins, Philadelphia (in press) Google Scholar
Biron CA, Sonnenfeld G, Welsh RM (1984) Interferon induces natural killer cell blastogenesis in vivo. J Leukoc Biol 35:31–37 PubMedCAS Google Scholar
Biron CA, Welsh RM (1982) Blastogenesis of natural killer cells during viral infection in vivo. J Immunol 129:2788–2795 PubMedCAS Google Scholar
Biron CA, Young HA, Kasaian MT (1990) Interleukin 2-induced proliferation of murine natural killer cells in vivo. J Exp Med 171: 173–188 ArticlePubMedCAS Google Scholar
Bukowski JF, Welsh RM (1985) Inability of interferon to protect virus-infected cells against lysis by natural killer (NK) cells correlates with NK cell-mediated antiviral effects in vivo. J Immunol 135:3537–3541 PubMedCAS Google Scholar
Bukowski JF, Woda BA, Habu S, Okumura K, Welsh RM (1983) Natural killer cell depletion enhances virus synthesis and virus-induced hepatitis in vivo. J Immunol 131:1531–1538 PubMedCAS Google Scholar
Cousens LP, Orange JS, Su HC, Biron CA (1997) Interferon-alpha/beta inhibition of interleukin 12 and interferon-gamma production in vitro and endogenously during viral infection. Proc Natl Acad Sci USA 94:634–639 ArticlePubMedCAS Google Scholar
Cousens LP, Peterson R, Hsu S, Dorner A, Altman JD, Ahmed R, Biron CA (1999) Two roads diverged: interferon alpha/beta- and interleukin 12-mediated pathways in promoting T cell interferon gamma responses during viral infection. J Exp Med 189: 1315–1328 ArticlePubMedCAS Google Scholar
Diefenbach A, Jamieson AM, Liu SD, Shastri N, Raulet DH (2000) Ligands for the murine NKG2D receptor: expression by tumor cells and activation of NK cells and macro phages. Nat Immunol 1:119–126 ArticlePubMedCAS Google Scholar
Doughty LA, Nguyen KB, Durbin JE, Biron CA (2001) A role for IFN-alpha/beta in virus infection induced sensitization to endotoxin. J Immunol 166:2658–2664 PubMedCAS Google Scholar
Gallimore A, Glithero A, Godkin A, Tissot AC, Pluckthun A, Elliott T, Hengartner H, Zinkernagel R (1998) Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes. J Exp Med 187:1383–1393 ArticlePubMedCAS Google Scholar
Karp CL, Biron CA, Irani DN (2000) Interferon beta in multiple sclerosis: is IL-12 suppression the key? Immunol Today 21:24–28 ArticlePubMedCAS Google Scholar
MacMicking J, Xie QW, Nathan C (1997) Nitric oxide and macrophage function. Annu Rev Immunol 15:323 350 ArticlePubMed Google Scholar
McIntyre KW, Welsh RM (1986) Accumulation of natural killer and cytotoxic T large granular lymphocytes in the liver during virus infection. J Exp Med 164:1667–1681 ArticlePubMedCAS Google Scholar
McRae BL, Semnani RT, Hayes MP, van Seventer GA (1998) Type I IFNs inhibit human dendritic cell IL-12 production and Thl cell development. J Immunol 160:4298–4304 PubMedCAS Google Scholar
Moskophidis D, Battegay M, Bruendler MA, Laine E, Gresser I, Zinkernagel RM (1994) Resistance of lymphocytic choriomeningitis virus to alpha/beta interferon and to gamma interferon. J Virol 68:1951–1955 PubMedCAS Google Scholar
Muller U, Steinhoff U, Reis LF, Hemmi S, Pavlovic J, Zinkernagel RM, Ague M (1994) Functional role of type I and type II interferons in antiviral defense. Science 264: 1918–1921 ArticlePubMedCAS Google Scholar
Nguyen KB, Cousens LP, Doughty LA, Pien GC, Durbin JE, Biron CA (2000) Interferon α/β-mediated inhibition and promotion of interferon β: STAT1 resolves a paradox. Nature Immunology 1:70–76 PubMedCAS Google Scholar
Orange JS, Biron CA (1996a) An absolute and restricted requirement for IL-12 in natural killer cell IFN-gamma production and antiviral defense. Studies of natural killer and T cell responses in contrasting viral infections. J Immunol 156: 1138–1142 CAS Google Scholar
Orange JS, Biron CA (1996b) Characterization of early IL-12, IFN-alpha/beta, and TNF effects on antiviral state and NK cell responses during murine cytomegalovirus infection. J Immunol 156: 4746–4756 PubMedCAS Google Scholar
Orange JS, Wang B, Terhorst C, Biron CA (1995b) Requirement for natural killer cell-produced interferon gamma in defense against murine cytomegalovirus infection and enhancement of this defense pathway by interleukin 12 administration. J Exp Med 182: 1045–1056 ArticlePubMedCAS Google Scholar
Pien GC, Biron CA (2000) Compartmental differences in NK cell responsiveness to IL-12 during lymphocytic choriomeningitis virus infection. J Immunol 164:994–1001 PubMedCAS Google Scholar
Pien G, Satoskar AR, Takeda K, Akira S, Biron CA (2000) Cutting edge: selective IL-18 requirements for induction of compartmental IFN-gamma responses during viral infection. J Immunol 165:4787–4791 PubMedCAS Google Scholar
Ramana CV, Grammatikakis N, Chemov M, Nguyen H, Goh KC, Williams BR, Stark GR (2000) Regulation of c-myc expression by IFN-gamma through Stat1-dependent and -independent pathways. Embo J 19:263–272 ArticlePubMedCAS Google Scholar
Riviere Y, Gresser I, Guillon JC, Bandu MT, Ronco P, Morel-Maroger L, Verroust P (1980) Severity of lymphocytic choriomeningitis virus disease in different strains of suckling mice correlates with increasing amounts of endogenous interferon. J Exp Med 152:633–640 ArticlePubMedCAS Google Scholar
Riviere Y, Gresser I, Guillon JC, Tovey MG (1977) Inhibition by anti-interferon serum of lymphocytic choriomeningitis virus disease in suckling mice. Proc Natl Acad Sci USA 74:2135–2139 ArticlePubMedCAS Google Scholar
Rothuizen LE, Buclin T, Spertini F, Trinchard I, Munafo A, Buchwalder PA, Ythier A, Biollaz J (1999) Influence of interferon beta-1a dose frequency on PBMC cytokine secretion and biological effect markers. J Neuroimmunol 99:131–141 ArticlePubMedCAS Google Scholar
Ruzek MC, Miller AH, Opal SM, Pearce BD, Biron CA (1997) Characterization of early cytokine responses and an interleukin (IL)-6-dependent pathway of endogenous glucocorticoid induction during murine cytomegalovirus infection. J Exp Med 185:1185–1192 ArticlePubMedCAS Google Scholar
Salazar-Mather TP, Hamilton TA, Biron CA (2000) A chemokine-to-cytokine-to-chemokine cascade critical in antiviral defense. J Clin Invest 105:985–993 ArticlePubMedCAS Google Scholar
Salazar-Mather TP, Orange JS, Biron CA (1998) Early murine cytomegalovirus (MCMV) infection induces liver natural killer (NK) cell inflammation and protection through macrophage inflammatory protein 1alpha (MIP-1alpha)-dependent pathways. J Exp Med 187:1–14 ArticlePubMedCAS Google Scholar
Sandberg K, Kemper P, Stalder A, Zhang J, Hobbs MV, Whitton JL, Campbell IL (1994) Altered tissue distribution of viral replication and T cell spreading is pivotal in the protection against fatal lymphocytic choriomeningitis in mice after neutralization of IFN-alpha/beta. J Immunol 153:220–231 PubMedCAS Google Scholar
Stepp SE, Dufourcq-Lagelouse R, Le Deist F, Bhawan S, Certain S, Mathew PA, Henter JI, Bennett M, Fischer A, de Saint Basile G, Kumar V (1999) Perforin gene defects in familial hemophagocytic lymphohistiocytosis. Science 286: 1957–1959 ArticlePubMedCAS Google Scholar
Tay CH, Welsh RM (1997) Distinct organ-dependent mechanisms for the control of murine cytomegalovirus infection by natural killer cells. J Virol 71:267–275 PubMedCAS Google Scholar
Welsh RM (1978) Cytotoxic cells induced during lymphocytic choriomeningitis virus infection of mice. I. Characterization of natural killer cell induction. J Exp Med 148: 163–181 ArticlePubMed Google Scholar
Wiertz E, Hill A, Tortorella D, Ploegh H (1997). Cytomegaloviruses use multiple mechanisms to elude the host immune response. Immunol Lett 57:213 216 ArticlePubMed Google Scholar
Yu CR, Ortaldo JR, Curiel RE, Young HA, Anderson SK, Gosselin P (1999) Role of a STAT binding site in the regulation of the human perforin promoter. J Immunol 162:2785–2790 PubMedCAS Google Scholar