Expression of Histocompatibility Antigens during the Growth Cycle of Cultured Lymphoid Cells (original) (raw)
This is publication number 793 from the Department of Experimental Pathology, Scripps Clinic and Research Foundation, La Jolla, California. This work was supported by United States Public Health Service grants AI 10180 and AI 07007 from the National Institutes of Health and grant 70–615 from the American Heart Association, Inc., and from the California Division of the American Cancer Society Senior fellowship number D-221.
References
- Alter, B. J., Schendel, D. J., Bach, M. L., Bach, F. H., Klein, J., Stimpling, J. H.: Cell-mediated lympholysis. Importance of serologically defined H-2 regions. J. exp. Med. 137, 1303 (1973)
PubMed CAS Google Scholar - Amos, D. B.: Serological differences between comparable diploid and tetraploid lines of three mouse ascites tumors. Ann. N.Y. Acad. Sci. 63, 706 (1956).
PubMed CAS Google Scholar - Balner, H., Gabb, B. W., Dersjant, H., Vreeswijk, W. van, Leeuwen, A. van, Rood, J. J.: In: Comparative genetics in monkeys, apes, and man (B. Chiarelli, ed.), p. 97. London: Academic Press 1971.
Google Scholar - Bernoco, D., Glade, P. R., Broder, S., Miggiano, V. C., Hirschhorn, K., Ceppellini, R.: Stability of HL-A and appearance of other antigens (LIVA) at the surface of lymphoblasts grown_in vitro_. Haematologica 54, 795 (1969).
PubMed CAS Google Scholar - Bertrams, J., Kuwert, E., Gallmeier, W. M., Reis, H. E., Schmidt, C. G.: Transient lymphocyte HL-A antigen “loss” in a case of irradiated M. Hodgkin. Tissue Antigens 1, 105 (1971).
PubMed CAS Google Scholar - Billing, R., Mittal, K. K., Terasaki, P. I.: Isolation of soluble HL-A antigens from normal human sera by ion exchange chromatography. Tissue Antigens 3, 251 (1973).
PubMed CAS Google Scholar - Bjaring, B., Klein, G., Popp, I.: Cyclic variations in the H-2 iso-antigenic expression of mouse lymphoma cells in vitro. Transplantation 8, 38 (1969).
PubMed CAS Google Scholar - Boenisch, T., Alper, C. A.: Isolation and properties of a glycine-rich β-glycoprotein of human serum. Biochim. biophys. Acta (Amst.) 221, 529 (1970).
CAS Google Scholar - Boyse, E. A., Stockert, E., Old, L. J.: Modification of the antigenic structure of the cell membrane by thymus-leukemia (TL) antibody. Proc. nat. Acad. Sci. (Wash.) 58, 954 (1967).
CAS Google Scholar - Braun, W. E., Grecek, D. R., Murphy, J. J.: Expanded HL-A phenotypes of human peripheral lymphocytes after trypsinization. Transplantation 13, 337 (1972).
PubMed CAS Google Scholar - Brautbar, C., Payne, R., Hayflick, L.: Fate of HL-A antigens in aging cultured human diploid cell strains. Exp. Cell Res. 75, 31 (1972).
PubMed CAS Google Scholar - Brautbar, C., Pellegrino, M. A., Ferrone, S., Payne, R., Reisfeld, R. A., Hayflick, L.: Fate of HL-A antigen in aging cultured human diploid cell strains. II. Quantitative absorption studies. Exp. Cell Res. 78, 367 (1973 a).
PubMed CAS Google Scholar - Brautbar, C., Stanbridge, E., Pellegrino, M. A., Ferrone, S., Reisfeld, R. A., Payne, R., Hayflick, L.: Expression of HL-A antigens on human fibroblasts after short and long term infection with mycoplasmas. J. Immunol. 111, 1783 (1973).
PubMed CAS Google Scholar - Buell, D. N., Fahey, J. L.: Limited periods of gene expression in immunoglobulin synthesizing cells. Science 164, 1524 (1969).
PubMed CAS Google Scholar - Burger, M. M.: A difference in the architecture of the surface membrane of normal and virally transformed cells. Proc. nat. Acad. Sci. (Wash.) 62, 994 (1969).
CAS Google Scholar - Byars, N., Kidson, C.: Programmed synthesis and export of immunoglobulin by synchronized myeloma cells. Nature (Lond.) 226, 648 (1970).
CAS Google Scholar - Charlton, R. K., Zmijewski, C. M.: Soluble HL-A7 antigen: Localization in the β- lipoprotein fraction of human serum. Science 170, 636 (1970).
PubMed CAS Google Scholar - Chessin, L. N., Bramson, S., Kuhns, W. J., Hirschhorn, K.: Studies on the A, B, O (H) blood groups on human cells in culture. Blood 25, 944 (1965).
PubMed CAS Google Scholar - Cikes, M.: Relationship between growth rate, cell volume, cell cycle kinetic and antigenic properties of cultured murine lymphoma cells. J. nat. Cancer Inst. 45, 979 (1970).
PubMed CAS Google Scholar - Cikes, M.: Expression of surface antigens on cultured tumor cells in relation to cell cycle. Transplant. Proc. 3, 1161 (1971).
Google Scholar - Cikes, M., Friberg, S., Jr.: Expression of H-2 and Moloney leukemia virus-transformed cell surface antigens in synchronized cultures of a mouse cell line. Proc. nat. Acad. Sci. (Wash.) 68, 566 (1971).
CAS Google Scholar - Cikes, M., Friberg, S., Klein, G.: Progressive loss of H-2 antigens with concomitant increase of cell-surface antigen (s) determined by Moloney leukemia virus in cultured murine lymphomas. J. nat. Cancer Inst. 50, 347 (1973).
PubMed CAS Google Scholar - Cikes, M., Klein, G.: Effect on inhibitors of protein and nucleic acid synthesis on the expression of H-2 and Moloney leukemia virus-determined cell surface antigens on cultured murine lymphoma cells. J. nat. Cancer Inst. 48, 509 (1972a).
PubMed CAS Google Scholar - Cikes, M., and Klein, G.: J. nat. Cancer Inst. 49, 1599 (1972b).
PubMed CAS Google Scholar - Cooper, N. R.: Activation of the complement system. Contemporary Topics in Molecular Immunology 2, 155 (1973).
PubMed CAS Google Scholar - Cowan, N., Milstein, M.: Automatic monitoring of biochemical parameters in tissue culture. Biochem. J. 128, 445 (1972).
PubMed CAS Google Scholar - Dausset, J.: Correlation between histocompatibility antigens and susceptibility to Illness. Progr. Clin. Immunol. 1, 183 (1973).
Google Scholar - Dick, H. M., Steel, C. M., Crichton, W. B.: HL-A typing of cultured peripheral lymphoblastoid cells. Tissue Antigens 2, 85 (1972).
PubMed CAS Google Scholar - Edidin, M.: Release of soluble H-2 alloantigens during disaggregation of mouse embryo tissue by a chelating agent. J. Embryol. exp. Morph. 16, 519 (1966).
PubMed CAS Google Scholar - Eijsvoogel, V. P., Du Bois, R., Melief, C. J. M., Zeylemaker, W. P., Raat-Koming, L., Groot-Kody, L. de: Lymphocyte activation and destruction in vitro in relation to MLC and HL-A. Transplant. Proc. 5, 1301 (1973).
PubMed CAS Google Scholar - Evans, W. H., Bruning, J. W.: Studies on the distribution of some histocompatibility antigens in mouse liver plasma membrane and microsomal fractions. Immunology 19, 735 (1970).
PubMed CAS Google Scholar - Everson, L. K., Plocinik, B., Rogentine, G. N., Jr.: HL-A expression on the Gl, S and G2 cell cycle stages of human lymphoid culture cells. Fed. Proc. 32, 1018 (1973).
Google Scholar - Ferrone, S., Cooper, N. R., Pellegrino, M. A., Reisfeld, R. A.: The lymphocytotoxic reaction: the mechanism of rabbit complement action. J. Immunol. 107, 939 (1971).
PubMed CAS Google Scholar - Ferrone, S., Cooper, N. R., Pellegrino, M. A., Reisfeld, R. A.: Interaction of histocompatibility (HL-A) antibodies and complement with synchronized human lymphoid cells in continous culture. J. exp. Med. 137, 55 (1973a).
PubMed CAS Google Scholar - Ferrone, S., Cooper, N. R., Pellegrino, M. A., Reisfeld, R. A.: Activation of human complement by human lymphoid cells sensitized with histocompatibility (HL-A) alloantisera. Proc. nat. Acad. Sci. (Wash.) 70, 3665 (1973).
CAS Google Scholar - Ferrone, S., Del Villano, B. C., Pellegrino, M. A., Lerner, R. A., Reisfeld, R. A.: Expression of HL-A antigens on the surface of cultured human lymphoid cells: Effect of inhibitors of protein and nucleic acid synthesis. Tissue Antigens 2, 447 (1972).
PubMed CAS Google Scholar - Ferrone, S., Pellegrino, M. A.: HL-A antigen, antibody and complement in the lymphocytotoxic reaction. Contemporary Topics in Molecular Immunology 2, 185 (1972).
Google Scholar - Ferrone, S., Pellegrino, M. A., Dierich, M. P., Reisfeld, R. A.: Effect of inhibitors of macromolecular synthesis on HL-A antibody mediated lysis of cultured lymphoblasts. Tissue Antigens (in press) (1974 a).
Google Scholar - Ferrone, S., Ting, A., Pellegrino, M. A., Terasaki, P. I., Reisfeld, R. A.: Detection of humoral presensitization in prospective recipients of kidney transplants by cultured human lymphoid cells. Submitted for publication (1974b).
Google Scholar - Fine, D. P., Marney, S. R., Jr., Colley, D. G., Sergent, J. S., Des Prez, R. M.: C3 shunt activation in human serum chelated with EGTA. J. Immunol. 109, 807 (1972).
PubMed CAS Google Scholar - Fujimoto, S., Chen, C. H., Sabbadini, E., Sehon, A. H.: Association of tumor and histocompatibility antigens in sera of lymphoma-bearing mice. J. Immunol. Ill, 1093 (1973).
PubMed CAS Google Scholar - Gibofsky, A., Terasaki, P. I.: Trypsinization of lymphocytes for HL-A typing. Transplantation 13, 192 (1972).
PubMed CAS Google Scholar - Götze, D., Pellegrino, M. A., Ferrone, S., Reisfeld, R. A.: Expression of H-2 antigen during growth of cultured tumor cells. Immunological Commun. 1, 533 (1972).
Google Scholar - Götze, D., Reisfeld, R. A.: Solubilization of H-2 antigens from mouse cultured lymphoid cells. J. Immunol. 112, 1643 (1974).
PubMed Google Scholar - Götze, O., Müller-Eberhard, H. J.: The C3 activator system: an alternate pathway of complement activation. J. exp. Med. 134, 90S (1971).
Google Scholar - Götze, O., Müller-Eberhard, H. J.: The role of properdin in the alternate pathway of complement activation. J. exp. Med. (in press) (1974).
Google Scholar - Goodkovsky, J., Lepow, I. H.: Functional relationship of factor B in the properdin system to C3 proactivation of human serum. J. Immunol 107, 1200 (1971).
Google Scholar - Goodkowski, I., Stewart, A. H., Lepow, I. H.: Relationship of C3 and factor A of the properdin system. J. Immunol. 111, 287 (1973).
Google Scholar - Grothaus, E. A., Wayne Flye, M., Yunis, E., Amos, D. B.: Human lymphocyte antigen reactivity modified by neuraminidase. Science 173, 542 (1971).
PubMed CAS Google Scholar - Harris, R.: Leukaemia antigens and immunity in man. Nature (Lond.) 241, 95 (1973).
CAS Google Scholar - Haugton, G.: Transplantation antigen of mice: Cellular localization of antigen determined by the H-2 locus. Transplantation 4, 238 (1966).
Google Scholar - Hellström, K. E., Möller, E.: Immunological and immunogenetic aspects of tumor transplantation. Progr. Allergy 9, 158 (1965).
Google Scholar - Hoecker, G., Hauschka, T. S.: Apparent loss of specific isoantigen in heteroploid transplanted tumor cells. Transplant. Bull. 3, 134 (1956).
Google Scholar - Hogman, C.: Blood group antigens A and B determined by means of mixed agglutination on cultured cells of human fetal kidney, liver, spleen, lung, heart and skin. Vox Sang. (Basel) 4, 319 (1959).
CAS Google Scholar - Howard, A., Pelc, S. R.: The cell growth cycle. Heredity 6, Suppl. 1, 261 (1953).
CAS Google Scholar - Karb, K., Goldstein, G.: Combination autoradiograph and membrane fluorescence in studing cell cycle transplantation antigen relationship. Transplantation 11, 569 (1971).
PubMed CAS Google Scholar - Klein, D., Merchant, D. J., Klein, J., Shreffler, D. C.: Persistence of H-2 and some non-H-2 antigens on long-term-cultured mouse lines cell. J. nat. Cancer Inst. 44, 1149 (1970).
PubMed CAS Google Scholar - Klein, J., Shreffler, D. C.: The H-2 model for the major histocompatability systems. Transplant. Rev. 6, 3 (1971).
PubMed CAS Google Scholar - Kolb, W. P., Haxby, J. A., Arroyave, C. M., Müller-Eberhard, H. J.: Molecular analysis of the membrane attack mechanism of complement. J. exp. Med. 135, 549 (1972).
PubMed CAS Google Scholar - Lerner, R. A., Hodge, L. D.: Gene expression in synchronized lymphocytes: studies on the control of synthesis of immunoglobulin polypeptides. J. Cell Physiol. 77, 265 (1971).
PubMed CAS Google Scholar - Lerner, R. A., Oldstone, M. B. A., Cooper, N. R.: Cell cycle-dependent immune Lysis of Moloney virus-transformed lymphocytes: presence of viral antigen, accessibility to antibody, and complement activation. Proc. nat. Acad. Sci. (Wash.) 68, 2584 (1971).
CAS Google Scholar - Liberti, P., Baglioni, C.: Synthesis of immunoglobulin and nuclear protein in synchronized mouse myeloma cells. J. Cell Physiol. 82, 113 (1973).
PubMed CAS Google Scholar - Lindahl, P., Leary, P., Gresser, I.: Enhancement by interferon of the expression of surface antigens on murine leukemia L1210 cells. Proc. nat. Acad. Sci. (Wash.) 70, 2785 (1973).
CAS Google Scholar - Mackintosh, P., Wallin, J., Hardy, D. A., Ling, N. R., Steel, C. M.: The interaction of normal lymphocytes and cells from lymphoid cell lines. IV. HL-A typing of the cell line cells. Immunology 24, 315 (1973).
PubMed CAS Google Scholar - Mann, D. L., Rogentine, G. N., Fahey, J. L., Nathenson, S. F.: Solubilization of human leukocyte membrane isoantigens. Nature (Lond.) 217, 1180 (1968).
CAS Google Scholar - Manson, L. A., Palm, J.: Intracellular distribution of transplantation antigens. In: The transplantation antigens (B. D. Kahan and R. A. Reisfeld, eds.), p. 141. New York: Academic Press 1972.
Google Scholar - May, J. E., Frank, M. M.: A new complement mediated cytolytic mechanism. The Cl-bypass activation pathway. Proc. nat. Acad. Sci. (Wash.) 70, 649 (1973).
CAS Google Scholar - Mittal, K. K., Ferrone, S., Mickey, M. R., Pellegrino, M. A., Reisfeld, R. A., Terasaki, P. I.: Specificity of lymphocytotoxic antihuman antibodies in normal rabbit sera. Tissue Antigens 3, 88 (1973a).
PubMed CAS Google Scholar - Mittal, K. K., Ferrone, S., Mickey, M. R., Pellegrino, M. A., Reisfeld, R. A., Terasaki, P. I.: Serological characterization of natural anti-human lymphocytotoxic antibodies in mammalian sera. Transplantation 16, 287 (1973b).
PubMed CAS Google Scholar - Miyajima, T., Hirata, A. A., Terasaki, P. I.: Escape from sensitization to HL-A antibodies. Tissue Antigens 2, 64 (1972).
PubMed CAS Google Scholar - Miyakawa, Y., Tanigaki, N., Kreiter, V. P., Moore, G. E., Pressman, D.: Characterization of soluble substances in the plasma carrying HL-A alloantigenic activity. Transplantation 15, 312 (1973).
PubMed CAS Google Scholar - Miyakawa, Y., Tanigaki, N., Yagi, Y., Pressman, D.: An efficient method for isolation of HL-A antigen from hematopoietic cell lines. J. Immunol. 107, 394 (1971).
PubMed CAS Google Scholar - Morris, P. J., Dumble, L. J.: Use of lymphoblastoid cell-lines to determine responsiveness in cadaveric renal transplantation. Lancet 1973 II, 16.
Google Scholar - Mueller, G. C.: Biochemical events in the animal cell cycle. Fed. Proc. 28, 1780 (1969).
PubMed CAS Google Scholar - Müller-Eberhard, H. J., Götze, O.: C3 proactivator convertase and its mode of action. J. exp. Med. 135, 1003 (1972).
PubMed Google Scholar - Old, L. J., Stockert, E., Kim, J. H., Boyse, E. A.: Antigenic modulation: loss of TL antigen from cells exposed to TL antibody. Study of the phenomenon in vitro. J. exp. Med. 127, 523 (1968).
PubMed CAS Google Scholar - Palm, J.: Serological detection of histocompatability antigens in two strains of rat. Transplantation 2, 603 (1964).
PubMed CAS Google Scholar - Papermaster, Y. M., Papermaster, B. W., Moore, G. E.: Histocompatability antigens of human lymphocytes in long term culture. Fed. Proc. 28, 379 (1969).
Google Scholar - Pasternak, C. A., Warmsley, A.M., Thomas, D. B.: Structural alterations in the surface membrane during the cell cycle. J. Cell Biol. 50, 562 (1971).
PubMed CAS Google Scholar - Patel, R., Terasaki, P. I.: Significance of the positive crossmatch test in kidney transplantation. new Engl. J. Med. 280, 735 (1999)
Google Scholar - Pegrum, G. D., Balfour, T. C., Evans, C. A., Middleton, V. L.: HL-A typing of “leukaemic” cells. Lancet 1971 1, 852.
PubMed CAS Google Scholar - Pellegrino, M. A., Ferrone, S., Natali, P. G., Pellegrino, A., Reisfeld, R. A.: Expression of HL-A antigens in synchronized cultures of human lymphocytes. J. Immunol. 108, 573 (1972a).
PubMed CAS Google Scholar - Pellegrino, M. A., Ferrone, S., Pellegrino, A.: A simple microabsorption technique for HL-A typing. Proc. Soc. exp. Biol. (N.Y.) 139, 484 (1972b).
CAS Google Scholar - Pellegrino, M. A., Ferrone, S., Pellegrino, A.: Serological detection of soluble HL-A antigens. In: The transplantation antigens (B. D. Kahan and R. A. Reisfeld, eds.), p. 433. New York: Academic Press 1972c.
Google Scholar - Pellegrino, M. A., Ferrone, S., Pellegrino, A., Reisfeld, R. A.: The Expression of HL-A Antigens During the Growth Cycle of Cultured Human Lymphoid Cells. Clin. Immunol. Immunopathol. 1, 182 (1973).
PubMed CAS Google Scholar - Pellegrino, M. A., Ferrone, S., Pellerrino, A. G., Oh, S. K., Reisfeld, R. A.: Evaluation of two sources of soluble HL-A Antigens: Platelets and Serum. Europ. J. Immunol, (in press) (1974).
Google Scholar - Peterson, D. F., Tobey, R. A., Anderson, E. C.: Synchronously dividing mammalian cells. Fed. Proc. 28, 1771 (1969).
Google Scholar - Pillmer, L., Blum, L., Lepow, I. H.: The properdin system and immunity: I. Demonstration and isolation of a new serum protein, Properdin, and its role in immune phenomena. Science 120, 279 (1954).
Google Scholar - Prescott, D. M.: Regulation of cell reproduction. Cancer Res. 28, 1815 (1968).
PubMed CAS Google Scholar - Puck, T. T., Steffan, J.: I. A method for localizing metabolic events within the life cycle, and its application to the action of colcemide and sublethal doses of X-Irr adiation. Biophys. J. 3, 379 (1963).
PubMed CAS Google Scholar - Reisfeld, R. A., Pellegrino, M., Papermaster B. W., Kahan, B. D.: HL-A antigens from a continuous lymphoid cell line derived from a normal donor. I. Solubilization and serological charactertization. J. Immunol. 104, 560 (1970).
PubMed CAS Google Scholar - Reisfeld, R. A., Pellegrino, M. A., Ferrone, S., Oh, S., Götze, D.: An approach to the characterization of lymphoid cell surface antigens. Atti. Accad. Naz. Lincei. Rend, (in Press).
Google Scholar - Rapaport, F. T., Hanaoka, T., Shimada, T., Cannon, F. D., Ferrebee, J. W.: Histocompatability studies in closely bred colony of dogs. I. Influence of leukocyte group antigens upon renal allograft survival in the unmodified host. J. exp. Med. 131, 881 (1970).
PubMed CAS Google Scholar - Rogentine, G. N., Jr., Gerber, P.: HL-A antigens of human lymphoid cells in longterm tissue culture. Transplantation 8, 28 (1969).
PubMed Google Scholar - Rogentine, G. N., Jr., Gerber, P.: Qualitative and quantitative comparison of HL-A Antigens on different lymphoid cell types from the same individuals. In: Histocompatability testing (P. I. Terasaki, ed.), p. 333. Copenhagen: Munksgaard 1970.
Google Scholar - Rood, J. J. van, Leeuween, A. van: HL-A and the group five system in Hodgkin’s disease. Transplant. Proc. 3, 1283 (1971).
Google Scholar - Rood, J. J. van, Leeuwen, A. van, Santen, M. C. van: Anti HL-A2 inhibitor in normal human serum. Nature (Lond.) 226, 366 (1970).
Google Scholar - Rosenberg, S. A., Einstein, A. B., Jr.: Sialic acids on the plasma membrane of cultured human lymphoid cells. J. Cell Biol. 53, 466 (1972).
PubMed CAS Google Scholar - Rosenfeld, C., Doré, J. F., Choquet, C., Venuat, A. M., Ajuria, E., Marholev, L., Wastiaux, J. P.: Variations in expression of cell membrane antigens by cultured cells. Transplantation 16, 279 (1973).
PubMed CAS Google Scholar - Sanderson, A. R.: HL-A substances from human spleens. Nature (Lond.) 220, 192 (1968).
CAS Google Scholar - Schlesinger, M., Amos, B. D.: Effect of neuraminidase on serological properties of murine lymphoid cells. Transplant. Proc. 3, 895 (1971).
PubMed CAS Google Scholar - Schultz, J. S., Shreffler, D. C.: Studies on the serum fraction containing soluble inhibitors of anti-HL-A sera. Transplantation 13, 186 (1972).
PubMed CAS Google Scholar - Seigler, H. F., Kremer, W. B., Metzgar, R. S., Ward, F. E., Taung, A. T., Amos, D. B.: HL-A antigenic loss in malignant transformation. J. nat. Cancer Inst. 46, 577 (1971).
PubMed CAS Google Scholar - Singer, S. J., Nicolson, G. L.: The fluid mosaic model of the structure of cell membranes. Science 175, 720 (1972).
PubMed CAS Google Scholar - Sirchia, A., Ferrone, S.: Normal human lymphocyte treated in vitro with the sulphydryl compound AET: relationship to the lymphocytes of PNH. Blood 37, 563 (1971).
PubMed CAS Google Scholar - Snell, G. D., Stimpfling, J. H.: Genetics of tissue transplantation. In: Biology of the laboratory mouse (E. L. Green, ed.). 2nd edition, p. 457. New York: Mraw-Hill 1966.
Google Scholar - Spiegelberg, H., Götze, O.: Conversion of C3 proactivator and activation of the alternate pathway of complement activation by different classes and subclasses of human immunoglobulins. Fed. Proc 31, 655 (1972).
Google Scholar - Stanner, C. P., Till, J. R.: DNA synthesis in individual L-strain mouse cells. Biochim. biophys. Acta (Amst.) 37, 406 (1960).
Google Scholar - Takahashi, M-, Yagi, Y., Moore, G. E., Pressman, D.: Immunoglobulin production in synchronized cultures of human hematopoietic cell lines. J. Immunol. 103, 834 (1969).
PubMed CAS Google Scholar - Ting, C. C., Herberman, R. B.: Inverse relationship of polyoma tumor-specific cell surface antigen to H-2 histocompatibility antigens. Nature (Lond.) New Biol. 232, 118 (1971).
CAS Google Scholar - Tobey, R. A., Peterson, D. F., Anderson, E. C., Puck, T. T.: Life cycle analsis of mammalian cells. 3. The inhibition of division in Chinese hamster cells by Puromycin and Actinomycin. Biophys. J. 6, 567 (1966).
PubMed CAS Google Scholar - Trinchieri, G., Bernoco, D., Curtoni, S. E., Miggiano, Y. C., Ceppellini, R.: Cell mediated lympholysis in man: relevance of HL-A antigens and antibodies. In: Histocompatibility testing, 1972. (J. Dausset, ed) p. 509. Copenhagen: Munksgaard, 1972.
Google Scholar - Walford, R. L., Smith, G. S., Waters, H.: Histocompatibility systems and disease states with particular reference to cancer. Transplant. Rev. 7, 78 (1971).
PubMed CAS Google Scholar - Warmsley, A. M. H., Pasternak, C. A.: The use of conventional and zonal centrifugation to study the life of mammalian cells. Phospholipid and monomolecular synthesis in neoplastic mast cells. Biochem. J. 119, 493 (1970).
PubMed CAS Google Scholar - Warmsley, A. M. H., Phillips, B., Pasternak, C. A.: The use of zonal centrifugation to study membrane formation during the life cycle of mammalian cells. Synthesis of “Marker” enzymes and other components of cellular organelles. Biochem. J. 120, 683 (1970).
PubMed CAS Google Scholar - Warren, L., Glick, M. C.: Membranes of animal cells. II. The metabolism and turnover of the surface membrane. J. Cell Biol. 37, 729 (1968).
PubMed CAS Google Scholar - Watanabe, S., Yagi, Y., Pressman, D.: Immunoglobulin production in synchronized cultures of human hematopoietic cell lines. II. Variation of synthetic and secretion activities during the cell cycle. J. Immunol. 797 (1973)
Google Scholar