Altered tetracycline resistance in pSC101 recombinant plasmids (original) (raw)

Summary

Investigation of tetracycline resistance genetically determined by the plasmid pSC101 and several recombinants of pSC101 containing of _Eco_RI generated DNA fragments inserted at the _Eco_RI site has revealed significant differences in the phenotypic expression of that resistance. The altered phenotypes of the recombinant plasmids may be the result of the location of the _Eco_RI site of pSC101, which has been determined to be near the genetic elements involved with tetracycline resistance.

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Authors and Affiliations

1. Department of Biochemistry and Biophysics, University of California, San Francisco, 94143, San Francisco, California, USA
   Robert C. Tait, Raymond L. Rodriguez & Herbert W. Boyer

Authors

1. Robert C. Tait
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2. Raymond L. Rodriguez
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3. Herbert W. Boyer
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Communicated by W. Gilbert

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Tait, R.C., Rodriguez, R.L. & Boyer, H.W. Altered tetracycline resistance in pSC101 recombinant plasmids.Molec. Gen. Genet. 151, 327–331 (1977). https://doi.org/10.1007/BF00268797

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• Received: 04 November 1976
• Issue Date: January 1977
• DOI: https://doi.org/10.1007/BF00268797

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