Epigenetic changes may contribute to the formation and spontaneous regression of retinoblastoma (original) (raw)
References
Benedict WF, Murphree AL, Banerjee A, Spina CA, Sparkes MC, Sparkes R (1983) Patient with 13 chromosome deletion: evidence that the retinoblastoma gene is a recessive cancer gene. Science 219: 973–975 Google Scholar
Bird AP (1986) CpG-rich islands and the function of DNA methylation. Nature 321: 209–213 Google Scholar
Bird AP, Southern EM (1978) Use of restriction enzymes to study eukaryotic DNA methylation. I. The methylation pattern in ribosomal DNA from Xenopus laevis. J Mol Biol 118: 27–47 Google Scholar
Bookstein R, Lee EYHP, To H, Young LJ, Sery TW, Hayes RC, Friedmann T, Lee WH (1988) Human retinoblastoma susceptibility gene: genomic organisation and analysis of heterozygous intragenic deletion mutants. Proc Natl Acad Sci USA 85: 2210–2214 Google Scholar
Buiting K, Passarge E, Horsthemke B (1988) Construction of a chromosome 15-specific linking library and identification of potential gene sequences. Genomics 3: 143–149 Google Scholar
Cavenee WK, Dryja TP, Phillips RA, Benedict WF, Godbout R, Gallie BL, Murphree AL, Strong LC, White RL (1983) Expression of recessive alleles by chromosomal mechanisms in retinoblastoma. Nature 305: 779–784 Google Scholar
Chandler LA, Ghazi H, Jones PA, Boukamp P, Fusenig NE (1987) Allele-specific methylation of the human c-Ha-ras-1 gene. Cell 50: 711–717 Google Scholar
De Bustros A, Nelkin BD, Silvermann A, Ehrlich G, Poiesz B, Baylin SB (1988) The short arm of chromosome 11 is a “hot spot” for hypermethylation in human neoplasia. Proc Natl Acad Sci USA 85: 5693–5697 Google Scholar
Feinberg AP, Vogelstein B (1983) Hypomethylation distinguishes genes of some human cancers from their normal counterparts. Nature 301: 89–92 Google Scholar
Friend SH, Bernards R, Rogelj S, Weinberg RA, Rapaport JM, Albert DM, Dryja TA (1986) A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma. Nature 323: 643–646 Google Scholar
Fung YKT, Murphree AL, T'Ang A, Quian J, Hinrichs SH, Benedict WF (1987) Structural evidence for the authenticity of the human retinoblastoma gene. Science 236: 1657–1661 Google Scholar
Gartler SM, Dyer KA, Graves JAM, Rocchi M (1985) A two step model for mammalian X-chromosome inactivation. In: Cantoni GL, Razin A (eds) Biochemistry and biology of DNA methylation. Liss, New York, pp 223–238 Google Scholar
Goelz SE, Vogelstein B, Hamilton B, Feinberg AP (1985) Hypomethylation of DNA from benign and malignant human colon neoplasms. Science 228: 187–190 Google Scholar
Holliday R (1987) The inheritance of epigenetic defects. Science 238: 163–170 Google Scholar
Horsthemke B, Greger V, Barnert HJ, Höpping W, Passarge E (1987) Detection of submicroscopic deletions and a DNA polymorphism at the retinoblastoma locus. Hum Genet 76: 257–261 Google Scholar
Human Gene Mapping 9 (1987) 9th International Workshop on Human Gene Mapping. Cytogenet Cell Genet 46: 1–762
Jahner D, Jaenisch R (1984) DNA methylation in early mammalian development. In: Razin A, Cedar H, Riggs AD (eds) DNA methylation, biochemistry and biological significance. Springer, Berlin Heidelberg New York, pp 189–219 Google Scholar
Jones PA (1985) Altering gene expression with 5-azacytidine. Cell 40: 485–486 Google Scholar
Kautainien TL, Jones PA (1986) DNA methyltransferase levels in tumorigenic and nontumorigenic cells in culture. J Biol Chem 261: 1594–1598 Google Scholar
Klein G (1987) The approaching era of the tumor suppressor genes. Science 238: 1539–1545 Google Scholar
Knudson AG (1971) Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sci USA 68: 820–823 Google Scholar
Kunkel LM, Smith KD, Boyer SH, Borgaonkor DS, Wachtel SS, Miller OJ, Breg WR, Jones HW, Rary JM (1977) Analysis of human Y-chromosome-specific reiterated DNA in chromosome variants. Proc Natl Acad Sci USA 74: 1245–1249 Google Scholar
Lee WH, Brookstein R, Hong F, Young LJ, Shew JY, Lee EYHP (1987) Human retinoblastoma susceptibility gene: cloning, identification, and sequence. Science 235: 1394–1399 Google Scholar
Lyon MF (1988) X-chromosome inactivation and the location and expression of X-linked genes. Am J Hum Genet 42: 8–16 Google Scholar
Reik W, Surani MA (1989) Genomic imprinting and embryonal tumours. Nature 338: 112–113 Google Scholar
Shmookler-Reis RJ, Goldstein S (1982) Interclonal varation in methylation patterns for expressed and non-expressed genes. Nucleic Acids Res 10: 4293–4304 Google Scholar
Silva AJ, White R (1988) Inheritance of allelic blueprints for methylation patterns. Cell 54: 145–152 Google Scholar
Sparkes RS, Sparkes MC, Wilson MG, Towner JW, Benedict WF, Murphree AL, Yunis JJ (1980) Regional assignment of esterase D and retinoblastoma to chromosome band 13q14. Science 208: 1042–1044 Google Scholar
Squire J, Dryja TP, Dunn J, Goddard A, Hofmann T, Musarella M, Willard HF, Becker AJ, Gallie BL, Phillips RA (1986) Cloning of the esterase D gene: a polymorphic gene probe closely linked to the retinoblastoma locus on chromosome 13. Proc Natl Acad Sci USA 83: 6573–6577 Google Scholar
Toguchida J, Ishizaki K, Sasaki MS, Nakamura Y, Ikenaga M, Kato M, Sugimot M, Kotoura Y, Yamamuro T (1989) Preferential mutation of paternally derived RB gene as the initial event in sporadic osteosarcoma. Nature 338: 156–158 Google Scholar
Young LJS, Lee EYHP, To H, Bookstein R, Shew JY, Donoso LA, Sery T, Giblin M, Shields JA, Lee WH (1988) Human esterase D gene: complete cDNA sequence, genomic structure, and application in the genetic diagnosis of human retinoblastoma. Hum Genet 79: 137–141 Google Scholar