Parental age and the origin of trisomy 21 (original) (raw)
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References
- Aymé S, Lippman-Hand A (1982) Maternal-age effect in aneuploidy: does altered embryonic selection play a role? Am J Hum Genet 34:558–565
Google Scholar - Aymé S, Mattei MG, Mikkelsen M, Aagesen L, Grinsted J, Nevin N, Dagna Bricarelli F, Arslanian A, Pierluigi M, Strigini P, Lungarotti S, Calabro A, Mariotti G, Baccichetti C, Artifoni L (1986) Factors involved in chromosomal nondisjunction: a European collaborative study. 7th International congress of Human Genetics, Berlin 1986 (abstr)
- Carothers AD (1987) Down syndrome and maternal age: the effect of erroneous assignment of parental origin. Am J Hum Genet 40: 147–150
Google Scholar - Caspersson T, Zech L, Johansson C, Modest EJ (1970) Identification of human chromosomes by DNA binding agents. Chromosoma 30:215–227
Google Scholar - Chandley AC (1981) The origin of chromosomal aberrations in man and their potential for survival and reproduction in the adult human population. Ann Génét (Paris) 24:5–11
Google Scholar - Dagna Bricarelli F, Arslanian A, Coviello DA, Ferro MA, Frateschi M, Gessaga M, Pierluigi M, Strigini P (1984) Origin of nondisjunction and “de novo” translocation in trisomy 21 syndrome: a study of 267 families. 17th Annual Meeting of the European Society of Human Genetics, Essen 1984 (abstr)
- Dagna Bricarelli F, Pierluigi M, Perroni L, Grasso M, Arslanian A, Sacchi N (1988) High efficiency in the attribution of parental origin of nondisjunction in trisomy 21 by both cytogenetic and molecular polymorphisms. Hum Genet 79:124–127
Google Scholar - Del Mazo J, Perez Castillo A, Abrisqueta JA (1982) Trisomy 21: origin of non-disjunction. Hum Genet 62:316–320
Google Scholar - Ferguson-Smith MA, Yates JRW (1984) Maternal age specific rates for aberration and factors influencing them: report of a collaborative study on 52965 amniocentesis. Prenat Diagn 4:5–44
Google Scholar - Hassold T, Chen N, Funkhouser J, Jooss T, Manuel B, Matsuura J, Matsuyama A, Wilson C, Yamane JA, Jacobs PA (1980a) A cytogenetic study of 1000 spontaneous abortions. Ann Hum Genet 44:151–178
Google Scholar - Hassold T, Jacobs P, Kline J, Stein Z, Warburton D (1980b) Effect of maternal age on autosomal trisomies. Ann Hum Genet 44:151–178
Google Scholar - Hook EB (1981) Down syndrome: its frequency in human populations and some factors pertinent to variation in rates. In: De la Cruz FF, Gerald PS (eds) Trisomy 21 (Down's syndrome). University Park Press, Baltimore, pp 77–93
Google Scholar - Hook EB (1983) Chromosome abnormalities and spontaneous fetal deaths following amniocentesis: further data and association with maternal age. Am J Hum Genet 35:110–116
Google Scholar - Hook EB (1984) Parental age and umbalanced Robertsonian translocation associated with Down syndrome and Patau syndrome: comparison with maternal and paternal age effects for 47,+21 and 47,+13. Ann Hum Genet 48:313–325
Google Scholar - Hook EB (1987) Issues in the analysis of data on paternal age and 47,+21: implications for genetic counseling for Down syndrome. Hum Genet 48:303–306
Google Scholar - Hook EB, Regal RR (1984) A search for a parental age effect upon cases of 47,+21 in which the extra chromosome is of paternal origin. Am J Hum Genet 36:413–421
Google Scholar - Hook EB, Cross PK, Schreinemachers DM (1983) Chromosomal abnormality rates at amniocentesis and in live-born infants. JAMA 249:2034–2038
Google Scholar - Magenis RE, Chamberlin J (1981) Parental origin of nondisjunction. In: De la Cruz FF, Gerald PS (eds) Trisomy 21 (Down's syndrome). University Park Press, Baltimore, pp 77–93
Google Scholar - Manning CH, Goodman HO (1981) Parental origin of chromosomes in Down's syndrome. Hum Genet 59:101–103
Google Scholar - Mantel N (1963) Chi-square tests with one degree of freedom; extensions of the Mantel-Haenzel procedure. J Am Statist Assoc 56: 690–700
Google Scholar - Martin RH, Rademaker AW (1987) The effect of age on frequency of chromosomal abnormalities in normal men. Am J Hum Genet 41:484–492
Google Scholar - Martin-De Leon PA, Williams MB (1987) Sexual behavior and Down syndrome: the biological mechanism. Am J Med Genet 27:693–700
Google Scholar - Mastroiacovo P, Musacchio P, Bertollini R (1982) L'indagine policentrica italiana sulle malformazioni congenite (IPIMC). Prospettive Pediatr 45:23–38
Google Scholar - Mattei JF, Aymé S, Mattei MG, Giraud F (1980) Maternal age and origin of nondisjunction in trisomy 21. J Med Genet 17:368–372
Google Scholar - Mikkelsen M, Hallberg A, Poulsen H (1976) Maternal and paternal origin of extra chromosome in trisomy 21. Hum Genet 32:17–21
Google Scholar - Mikkelsen M, Poulsen H, Gristed J, Lange A (1980) Non disjunction in trisomy 21: study of chromosomal heteromorphisms in 110 families. Ann Hum Genet 44:17–28
Google Scholar - Penrose LS (1963) The relative effects of paternal and maternal age in mongolism. J Genet 27:219–224
Google Scholar - Peters GB, Ford JH, Nicholl JK (1987) Trisomy 21 mosaicism and maternal age effect. Lancet I:1202–1203
Google Scholar - Polani EP (1981) Chiasmata, Down syndrome, and nondisjunction an overview. In: De la Cruz FF, Gerald PS (eds) Trisomy 21 (Down's syndrome). University Park Press, Baltimore, pp 111–130
Google Scholar - Roberts DH, Callows MC (1980) Origin of the additional chromosome in Down's syndrome: a study of 20 families. J Med Genet 17:363–367
Google Scholar - Rothman KJ (1979) Epidemiologic analysis with a programmable calculator. NIH publ 79-1649, Washington, DC, p 6
- Stene J, Stene E, Stengel-Rutkowski S, Murken JD (1981) Paternal age and Down's syndrome. Data from prenatal diagnosis (DFG). Hum Genet 59:119–124
Google Scholar - Stene E, Stene J, Stengel-Rutkowski S (1987) A reanalysis of the New York State prenatal diagnosis data on Down's syndrome and paternal age effects. Hum Genet 77:299–302
Google Scholar - Stein Z, Stein W, Susser M (1986) Attrition of trisomies as a maternal screening device: an explanation of the association of trisomy 21 with maternal age. Lancet I:944–947
Google Scholar - Strigini P, Sansone R, Landucci M, Pierluigi M, Forni GL, Dagna Bricarelli F (1988) Germ cells mutation by X-rays: the Down's syndrome model. International Symposium on Perinatal and Multigenerational Carcinogenesis, Leningrad 1988 (abstr)
- Sved JA, Sandler L (1981) Relation of maternal age effect in Down syndrome to nondisjunction. In: De la Cruz FF, Gerald PS (eds) Trisomy 21 (Down's syndrome). University Park Press, Baltimore, pp 95–98
Google Scholar - Wagenbichler P, Killian W, Rett A, Schnedl W (1976) Origin of the extra chromosome no. 21 in Down's syndrome. Hum Genet 32: 13–16
Google Scholar - Zelen M (1971) The analysis of several 2×2 contingency tables. Biometrika 58:129–137
Google Scholar