A mobile group II intron of a naturally occurring rearranged mitochondrial genome in Kluyveromyces lactis (original) (raw)

Summary

Mitochondrial intron content is variable in the yeast Kluyveromyces lactis. Strains can be divided into three classes depending on the structure of the cytochrome oxidase subunit 1 (COX1) gene: (1) those containing intron K1 cox1.1, (2) those containing K1 cox1.2, 3 and 4 and, (3) those that contain all four introns. In addition, strains belonging to the first class (designated Type B strains), have an altered mitochondrial gene order relative to strains from classes (2) and (3) (Type A, Hardy et al. 1989). Crossing experiments reveal that K1 cox1.1 (a group II intron) transfers at high frequency (89%) to mitochondrial genomes lacking this intron. By contrast, the mobility of the remaining introns (all group I) is of the order of 7%.

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Author notes

1. P. J. Skelly
   Present address: Department of Tropical Public Health, Harvard School of Public Health, 665 Huntington Avenue, 02115, Boston, MA, USA

Authors and Affiliations

1. Molecular and Population Genetics Group, Research School of Biological Sciences, Australian National University, GPO Box 475, 2601, Canberra, ACT, Australia
   P. J. Skelly, C. M. Hardy & G. D. Clark-Walker

Authors

1. P. J. Skelly
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2. C. M. Hardy
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3. G. D. Clark-Walker
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Communicated by R. J. Schweyen

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Skelly, P.J., Hardy, C.M. & Clark-Walker, G.D. A mobile group II intron of a naturally occurring rearranged mitochondrial genome in Kluyveromyces lactis.Curr Genet 20, 115–120 (1991). https://doi.org/10.1007/BF00312773

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• Received: 18 February 1991
• Issue Date: July 1991
• DOI: https://doi.org/10.1007/BF00312773

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