Nonsense suppressors partially revert the decrease of the mRNA level of a nonsense mutant allele in yeast (original) (raw)

Summary

suc2° is a naturally occurring amber mutant allele of the yeast invertase structural gene SUC2. Strains carrying suc2° had only 10% of the wild type invertase-specific mRNA level. Amber suppressors, which allowed suc2° strains to ferment sucrose caused an increase of the _SUC_-specific mRNA level.

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Author notes

1. D. Gozalbo
   Present address: Departament de Microbiologia, Facultat de Farmacia, Universitat de Valencia, Avgda Blasco Ibanez 13, E-46010, Valencia, Spain

Authors and Affiliations

1. Institut für Mikrobiologie, Technische Hochschule Darmstadt, Schnittspahnstrasse 10, D-6100, Darmstadt, Germany
   D. Gozalbo & S. Hohmann

Authors

1. D. Gozalbo
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2. S. Hohmann
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Communicated by K. Wolf

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Gozalbo, D., Hohmann, S. Nonsense suppressors partially revert the decrease of the mRNA level of a nonsense mutant allele in yeast.Curr Genet 17, 77–79 (1990). https://doi.org/10.1007/BF00313252

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• Received: 14 October 1989
• Issue Date: January 1990
• DOI: https://doi.org/10.1007/BF00313252

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