A gene affecting production of the Caenorhabditis elegans dauer-inducing pheromone (original) (raw)
Summary
A nematode mutant lacking pheromone activity does not enter the developmentally arrested dispersal stage called the dauer larva unless exogenous pheromone is added to the growth medium, indicating that the pheromone is required for wild-type dauer larva formation. In contrast, a class of temperature-sensitive mutant forms dauer larvae even in the absence of detectable pheromone, indicating that such mutants bypass the normal pheromone requirement. A rapid bioassay of pheromone produced by individual nematodes has been developed for genetic analysis of pheromone production.
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Author notes
- James W. Golden
Present address: Department of Biophysics and Theoretical Biology, University of Chicago, 60637, Chicago, Illinois, USA
Authors and Affiliations
- Division of Biological Sciences, University of Missouri, Tucker Hall, 65211, Columbia, Missouri, USA
James W. Golden & Donald L. Riddle
Authors
- James W. Golden
You can also search for this author inPubMed Google Scholar - Donald L. Riddle
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Communicated by G.R. Fink
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Golden, J.W., Riddle, D.L. A gene affecting production of the Caenorhabditis elegans dauer-inducing pheromone.Mol Gen Genet 198, 534–536 (1985). https://doi.org/10.1007/BF00332953
- Received: 15 September 1984
- Issue Date: March 1985
- DOI: https://doi.org/10.1007/BF00332953