Effects of inorganic phosphate on the contractile mechanism (original) (raw)

Summary

Inorganic phosphate in millimolar concentrations reduces contractile tension, but increases the speed and the oscillation frequency of glycerinated insect fibrillar muscle, while power output and ATPase are little affected.

Zusammenfassung

Anorganisches Phosphat hemmt die contractile Spannung und erhöht die Kontraktionsgeschwindigkeit und Oscillationsfrequenz glycerinierter fibrillärer Insektenmuskeln (Lethocerus maximus), während die mechanische Leistung und die ATPase-Aktivität kaum beeinflußt werden.

Access this article

Log in via an institution

Subscribe and save

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Abbott, R. H., Mannherz, H. G.: The activation by ADP and temperature increase of tension and ATPase activity of insect fibrillar muscle. Pflügers Arch.321, 223–232 (1970).
    Google Scholar
  2. Barany, M.: ATPase activity of myosin correlated with speed of muscle shortening. J. gen. Physiol.50, 197–218 (1967).
    Google Scholar
  3. Gillis, J. M., Maréchal, G.: Resynthesis of ATP in glycerinated fibers stretched during contraction. Proceed. of the 3rd. Int. Biophysics Congr.8, 129-9/3, p. 271 (1969).
    Google Scholar
  4. Jewell, B. R., Rüegg, J. C.: Oscillatory contraction of insect fibrillar muscle after glycerol extraction. Proc. roy. Soc. B,164, 428–459 (1966).
    Google Scholar
  5. Machin, K. E., Pringle, J. W. S.: The physiology of insect fibrillar muscle. III. The effect of sinusoidal changes of length on a beetle flight muscle. Proc. roy. Soc. B,152, 311 (1960).
    Google Scholar
  6. Mannherz, H. G.: On the reversibility of the biochemical reactions of muscular contractions during the absorption of negative work. FEBS Letters10, 233–236 (1970).
    Google Scholar
  7. —, Schirmer, R. H.: Die Molekularbiologie der Bewegung. Chemie in unserer Zeit6, 165–176 (1970).
    Google Scholar
  8. Schädler, M., Steiger, G. J., Rüegg, J. C.: Tension transients in glycerol-extracted fibers of insect fibrillar muscle. Experientia (Basel)25, 942–943 (1969).
    Google Scholar
  9. Steiger, G. J., Rüegg, J. C.: Energetics and efficiency in the isolated contractile machinery of an insect fibrillar muscle at various frequensies of oscillation. Pflügers Arch.307, 1–21 (1969).
    Google Scholar
  10. Taylor, E. W., Lymn, R. W., Moll, G.: Myosin product complex and its effect on the steady rate of nucleoside triphosphate hydrolysis. Biochemistry9, 2984–2991 (1970).
    Google Scholar
  11. Thorson, J., White, D. C. S.: Distributed representations for actin-myosin interaction in the oscillatory contraction of muscle. Biophys. J.9, 360–390 (1969).
    Google Scholar
  12. Ulbrich, M., Rüegg, J. C.: Stretch induced formation of ATP-32P in glycerinated fibers of insect flight muscle. Experientia (Basel)27, 45–46 (1971).
    Google Scholar

Download references

Author information

Authors and Affiliations

  1. Institut für Zellphysiologie, Ruhr-Universität, Bochum
    J. C. Rüegg, M. Schädler, G. J. Steiger & G. Müller

Authors

  1. J. C. Rüegg
    You can also search for this author inPubMed Google Scholar
  2. M. Schädler
    You can also search for this author inPubMed Google Scholar
  3. G. J. Steiger
    You can also search for this author inPubMed Google Scholar
  4. G. Müller
    You can also search for this author inPubMed Google Scholar

Rights and permissions

About this article

Cite this article

Rüegg, J.C., Schädler, M., Steiger, G.J. et al. Effects of inorganic phosphate on the contractile mechanism.Pflugers Arch. 325, 359–364 (1971). https://doi.org/10.1007/BF00592176

Download citation

Key-Words

Schlüsselwörter