Aghajanian GK, Bloom FE (1967) The formation of synaptic junctions in developing rat brain: a quantitative electron-microscopic study. Brain Res 6:716–727 Google Scholar
Allan W, Herndon CN, Dudley FC (1943/1944) Some examples of the inheritance of mental deficiency: apparently sexlinked idiocy and microcephaly. Am J Ment Defic 48:325–334 Google Scholar
Belonoschkin B (1954) Spermiogenesis in elderly men. Fertil Steril 5:182–192 Google Scholar
Bickers DS, Adams RD (1949) Hereditary stenosis of the aqueduct of Sylvius as a cause of congenital hydrocephalus. Brain 74:246–262 Google Scholar
Borjeson M, Forssman H, Lehmann O (1962) An X-linked, recessively inherited syndrome characterized by grave mental deficiency, epilepsy and endocrine disorders. Acta Med Scand 171:13–21 Google Scholar
Bostrom K, Brun A (1971) Testicular changes in association with malformation of the central nervous system and mental retardation. Acta Pathol Microbiol Scand [A] 79:249–256 Google Scholar
Bowen P, Bierderman B, Swallow KA (1978) The X-linked syndrome of macro-orchidism and mental retardation: Further observations. Am J Med Genet 2:409–414 Google Scholar
Brown WT, Mezzacappa PM, Jenkins EC (1981) Screening for fragile X syndrome by testicular size measurement. Lancet II:1055 Google Scholar
Brown WT, Jenkins EC, Freidman E, Brooks J, Wisniewski K, Raguthu S, French J (1982) Autism is associated with the fragile X syndrome. J Autism Dev Disord 12:303–308 Google Scholar
Cantu MM, Scaglia HE, Medina M, Gonzalez-Diddi M, Morato T, Moreno ME, Perez-Palacios G (1976) Innerited congenital normofunctional testicular hyperplasia and mental deficiency. Hum Genet 33:23–33 Google Scholar
Cantu JM, Scaglia HE, Gonzalez-Diddi M, Hernandez-Jauregui P, Morato T, Moreno ME, Giner J, Alcantar A, Herrera D, Perez-Palacios G (1978) Inherited congenital normofunctional testicular hyperplasia and mental deficiency. A corroborative study. Hum Genet 41:331–339 Google Scholar
DeGroot D, Vrensen G (1978) Postnatal development of synaptic contact zones in the visual cortex of rabbits. Brain Res 147:362–369 Google Scholar
Deroover J, Fryns JP, Parloir C, Van Den Berghe H (1977) X-linked recessively inherited non-specific mental retardation. Report of a large family. Ann Genet 20:263–268 Google Scholar
Dunn HG, Renpenning H, Gerrard JW, Miller JR, Tabata T, Federoff S (1963) Mental retardation as a sex-linked defect. Am J Ment Defic 67:827–848 Google Scholar
Edwards JH (1961) The syndrome of sex-linked hydrocephalus. Arch Dis Child 36–486
Fried K (1973) X-linked mental retardation and/or hydrocephalus. Clin Genet 3:258–263 Google Scholar
Hafez ESE (1976) Reproductive senescence. In: Hafez ESE (ed) Aging and reproductive physiology. Perspecitives in human reproduction, vol 2. Ann Arbor Science, Ann Arbor Google Scholar
Huttenlocher PR (1974) Dendritic development in neocortex of children with mental defect and infantile spasms. Neurology 24:203–210 Google Scholar
Jenkins EC, Brown WT, Brooks J, Duncan CJ, Rudelli RD, Wisniewski HM (1984) Experience with prenatal fragile X detection. Am J Med Genet 17:215–239 Google Scholar
Klinger HP (1972) Rapid processing primary embryonic tissue for chromosome banding pattern analysis. Cytogenetics 11:424–435 Google Scholar
Lowenthal A, Bruyn GW (1968) Calcification of the striopallido dentate system. In: Vinken PJ, Bruyn GW (eds) Diseases of the basal ganglia. Handbook of clinical neurology, vol 6. North Holland, Amsterdam, pp 703–725 Google Scholar
Mancini RE, Lavieri JC, Muller F, Andrada JA, Saraceni DJ (1966) Effect of prednisolone upon normal and pathologic human spermatogenesis. Fertil Steril 17:500–513 Google Scholar
Marin-Padilla M (1972): Structural organization of the cerebral cortex in human chromosomal aberrations. A Golgi study. Brain Res 44:625–629 Google Scholar
Marin-Padilla M (1974) Structural organization of the cerebral cortex (motor area) in human chromosomal aberrations. A Golgi study. ID (13–15) trisomy, Patau syndrome. Brain Res 66:375–391 Google Scholar
Marin-Padilla M (1975) Abnormal neuronal differentiation (functional maturation) in mental retardation. Birth Defects 11:133–153 Google Scholar
Marin-Padilla M (1976) Pyramidal cell abnormalities in the motor cortex of child with Down's syndrome. A Golgi study. J Comp Neurol 167:63–82 Google Scholar
Menkes JH, Phillippart M, Clark DB (1964) Hereditary partial agenesis of corpus callosum. Arch Neurol 11:198–208 Google Scholar
Nielsen KG (1983) Diagnosis of the fragile X syndrome (Martin-Bell syndrome). Clinical findings in 27 males with fragile site at Xq28. J Ment Defic Res 27:211–226 Google Scholar
Opitz JM, Sutherland GR (1984) Conference report: International workshop on the fragile X and X-linked mental retardation. Am J Med Genet 17:5–94 Google Scholar
Oshima H, Nankin HR, Troen P, Yoshida K, Ochi-Ai K (1977) Leydig cell number and function in infertile men. In: Troen P, Nankin HR (eds) The testis in normal and infertile men. Raven Press, New York, pp 445–455 Google Scholar
Purpura DP (1974) Dendritic spine “dysgenesis” and mental retardation. Science 186:1126–1128 Google Scholar
Rai KR, Sawitsky A, Cronkite EP, Chanana AD, Levy RN, Pasternak CK (1975) Clinical staging of chronic lymphocytic leukemia. Blood 46:219–234 Google Scholar
Renpenning H, Ferrard JW, Zaleski WA, Tabata T (1962) Familial sex-linked mental retardation. Can Med Assoc J 87:954–956 Google Scholar
Rhoads FA (1982) X-linked mental retardation and fragile X or marker X syndrome. Pediatrics 69:668–669 Google Scholar
Rudelli RD, Jenkins EC, Wisniewski K, Moretz R, Byrne J, Brown WT, (1983) Testicular size in fetal fragile X syndrome. Lancet I:1221–1222 Google Scholar
Ruvalcaba RHA, Myhre SA, Roosen-Runge EC, Beckwith JB (1977) X-linked mental deficiency. Megalotestes syndrome. JAMA 238:1646–1650 Google Scholar
Sargent JW, McDonald JR (1948) A method for the quantitative estimate of Leydig cells in the human testis. Proc Staff Meet Mayo Clin 23:249–254 Google Scholar
Scheibel AB (1979) Aging in human motor control systems. In: Ordy JM, Brizzees K (eds) Sensory systems and communication in the elderly, vol 10: Aging. Raven Press, New York, pp 297–310 Google Scholar
Scheibel ME, Tomiyasu U, Scheibel AB (1977) The aging human Betz cell. Exp Neurol 56:598–609 Google Scholar
Scott BS, Becker LE, Petit TL (1983) Neurobiology of Down's syndrome. Prog Neurobiol 21:199–237 Google Scholar
Smith RD, Fineman RM, Myers GG (1980) Short stature, psychomotor retardation, and unusual facial appearance in two brothers. Am J Med Genet 7:5–9 Google Scholar
Sovik O, Van Der Hagen CB, Loken AC (1977) X-linked aqueductal stenosis. Clin Genet 11:416 Google Scholar
Suetsugu M, Mahraein P (1980) Spine distribution along the apical dendrites of the pyramidal neurons in Down syndrome. A quantitative Golgi study. Acta Neuropathol (Berl) 50:207–210 Google Scholar
Sutherland GR (1977) Fragile sites on human chromosomes: Demonstration of their dependence on the type of tissue culture medium. Science 197:265–266 Google Scholar
Sylvester PE (1973) The testes in the mentally handicapped. J Ment Defic Res 17:52–57 Google Scholar
Takashima S, Becker LE, Armstrong DL, Chan FW (1981) Abnormal neuronal development in the visual cortex of the human fetus and infant with Down's syndrome. A quantitative and qualitative Golgi study. Brain Res 225:1–21 Google Scholar
Turner G, Jacobs P (1983) Marker (X)-linked mental retardation. Adv Hum Genet 13:83–112 Google Scholar
Turner G, Eastman E, Casey J, Mcleay A, Procopis P, Turner B (1975) X-linked mental retardation associated with macroorchidism. J Med Genet 21:367–371 Google Scholar
Williams RS, Hauser SL, Purpura DP, DeLong GR, Swisher CN (1980) Neuropathologic studies performed in four retarded persons with autistic behavior. Autism and Mental Retardation. Arch Neurol 37:749–753 Google Scholar
Wisniewski K, French J, Fernando S, Brown WT, Jenkins EC, Friedman E, Hill AL, Miezejeski CM (1985) Fragile X syndrome. Associated neurological abnormalities and developmental disabilities. Annals Neurol (in press)
Wong TW, Strauss FH, Worne NE (1973) Testicular biopsy in the study of male infertility. I. Testicular causes of infertility. Arch Pathol Lab Med 95:151–159 Google Scholar
Zachman M, Prader A, Kind HP, Baflinger H, Budlinger H (1974) Testicular volume during adolescence. Helv Paediatr Acta 29:61–72 Google Scholar