ADP-ribosylation factors: a family of ∼20-kDa guanine nucleotide-binding proteins that activate cholera toxin (original) (raw)

References

1. Gill DM: The arrangement of subunits in cholera toxin. Biochemistry 15: 1242–1248, 1976
   PubMed Google Scholar
2. Gill DM: Mechanism of action of cholera toxin. Adv Cyclic Nucleotide Res 8: 85–118, 1977
   PubMed Google Scholar
3. Moss J, Vaughan M: Participation of guanine nucleotide-binding protein cascade in activation of adenylyl cyclase by cholera toxin (choleragen). In: R. Iyengar and L. Birnbaumer (eds). G. Proteins, Academic Press, San Diego, CA, 1990, pp 179–200
   Google Scholar
4. Mekalanos JJ, Collier RJ, Romig WR: Enzymic activity of cholera toxin. II. Relationships to proteolytic processing, disulfide bond reduction, and subunit composition. J Biol Chem 254: 5855–5861, 1979
   PubMed Google Scholar
5. Moss J, Stanley SJ, Lin MC: NAD glycohydrolase and ADP-ribosyltransferase activities are intrinsic to the A1 peptide of choleragen. J Biol Chem 254: 11993–11996, 1979
   PubMed Google Scholar
6. Moss J, Manganiello VC, Vaughan M: Hydrolysis of nicotinamide adenine dinucleotide by choleragen and its A protomer: possible role in the activation of adenylate cyclase. Proc Natl Acad Sci USA 73: 4424–4427, 1976
   PubMed Google Scholar
7. Moss J, Vaughan M: Mechanism of action of choleragen. Evidence for ADP-ribosyltransferase activity with arginine as an acceptor. J Biol Chem 252: 2455–2457, 1977
   PubMed Google Scholar
8. Mekalanos JJ, Collier RJ, Romig WR: Enzyme activity of cholera toxin. I. New methods of assay and the mechanism of ADP-ribosyl transfer J Biol Chem 254: 5849–5854, 1979
   PubMed Google Scholar
9. Moss J, Vaughan M: Isolation of an avian erythrocyte protein possessing ADP-ribosyltransferase activity and capable of activating adenylate cyclase. Proc Natl Acad Sci USA 75: 3621–3624, 1978
   PubMed Google Scholar
10. Moss J, Stanley SJ, Watkins PA, Vaughan M: ADP-ribosyltransferase activity of mono- and multi-(ADP-ribosylated) choleragen. J Biol Chem 255: 7835–7837, 1980
    PubMed Google Scholar
11. Trepel JB, Chuang D-M, Neff NH: Transfer of ADP-ribose from NAD to choleragen: A subunit acts as a catalyst and acceptor protein. Proc Natl Acad Sci USA 74: 5440–5442, 1977
    PubMed Google Scholar
12. Cassel D, Pfeuffer T: Mechanism of cholera toxin action: covalent modification of the guanyl nucleotide-binding protein of the adenylate cyclase system. Proc Natl Acad Sci USA 75: 2669–2673, 1978
    PubMed Google Scholar
13. Gill DM, Meren R: ADP-ribosylation of membrane proteins catalyzed by cholera toxin; basis of the activation of adenylate cyclase. Proc Natl Acad Sci USA 75: 3050–3054, 1978
    PubMed Google Scholar
14. Johnson GL, Kaslow HR, Bourne HR: Genetic evidence that cholera toxin substrates are regulatory components of adenylate cyclase. J Biol Chem 253: 7120–7123, 1978
    PubMed Google Scholar
15. Northup JK, Sternweis PC, Smigel MD, Schleifer LS, Ross EM, Gilman AG: Purification of the regulatory component of adenylate cyclase. Proc Natl Acad Sci USA 77: 6516–6520, 1980
    PubMed Google Scholar
16. Finkelstein RA: Cholera. CRC Crit Rev Microbiol 2: 553–623, 1973
    Google Scholar
17. Kelley MT: Cholera: a worldwide perspective. Pediat Infect Dis 5: S101-S105, 1986
    Google Scholar
18. Gill DM: Involvement of nicotinamide adenine dinucleotide in the action of cholera toxin_in vitro_. Proc Natl Acad Sci USA 72: 2064–2068, 1975
    PubMed Google Scholar
19. Enomoto K, Gill DM: Requirement for guanosine triphosphate in the activation of adenylate cyclase by cholera toxin. J Supramol Struct 10: 51–60, 1979
    PubMed Google Scholar
20. Moss J, Vaughan M: Choleragen activation of solubilized adenylate cyclase: requirement for GTP and protein activator for demonstration of enzymatic activity. Proc Natl Acad Sci USA 74: 4396–4400, 1977
    PubMed Google Scholar
21. Lin MC, Welton AF, Berman MF: Essential role of GTP in the expression of adenylate cyclase activity after cholera toxin treatment. J Cyclic Nucleotide Res 4: 159–168, 1978
    PubMed Google Scholar
22. Nakaya S, Moss J, Vaughan M: Effects of nucleoside triphosphates on choleragen-activated brain adenylate cyclase. Biochemistry 19: 4871–4874, 1980
    PubMed Google Scholar
23. Enomoto K, Gill DM: Cholera toxin activation of adenylate cyclase. Roles of nucleoside triphosphates and a macromolecular factor in the ADP-ribosylation of the GTP-dependent regulatory component. J Biol Chem 255: 1252–1258, 1980
    PubMed Google Scholar
24. Gill DM, Meren R: A secondary guanyl nucleotide-binding site associated with adenylate cyclase. Distinct nucleotides activate adenylate cyclase and permit ADP-ribosylation by cholera toxin. J Biol Chem 258: 11908–11914, 1983
    PubMed Google Scholar
25. LeVine H III, Cuatrecasas P: Activation of pigeon erythrocyte adenylate cyclase by cholera toxin. Partial purification of an essential macromolecular factor from horse erythrocyte cytosol. Biochim Biophys Acta 672: 248–261, 1981
    PubMed Google Scholar
26. Schleifer LS, Kahn RA, Hanski E, Northup JK, Sternweis PC, Gilman AG: Requirements for cholera toxin-dependent ADP-ribosylation of the purified regulatory component of adenylate cyclase. J Biol Chem 257: 20–23, 1982
    PubMed Google Scholar
27. Pinkett MO, Anderson WB: Plasma membrane-associated component(s) that confer(s) cholera toxin sensitivity to adenylate cyclase. Biochim Biophys Acta 714: 337–343, 1982
    PubMed Google Scholar
28. Gill DM, Woolkalis MJ: [32P]ADP-ribosylation of proteins catalyzod by cholera toxin and related heat-labile enterotoxins. Methods Enzymol 165: 235–245, 1988
    PubMed Google Scholar
29. Schmidt GJ, Huber LJ, Weiter JJ: A-protein catalyzes the ADP-ribosylation of G-protein from cow rod outer segments. J Biol Chem 262: 14333–14336 1987
    PubMed Google Scholar
30. Gill DM, Coburn J: ADP-ribosylation by cholera toxin: functional analysis of a cellular system that stimulates the enzymatic activity of cholera toxin fragment A1. Biochemistry 26: 6364–6371, 1987
    PubMed Google Scholar
31. Woolkalis M, Gill DM, Coburn J: Assay and purification of cytosolic factor required for cholera toxin activity. Methods Enzymol 165: 246–249, 1988
    PubMed Google Scholar
32. Kahn RA, Gilman AG: Purification of a protein cofactor required for ADP-ribosylation of the stimulatory regulatory component of adenylate cyclase by cholera toxin. J Biol Chem 259: 6228–6234, 1984
    PubMed Google Scholar
33. Kahn RA, Gilman AG: The protein cofactor necessary for ADP-ribosylation of Gs by cholera toxin is itself a GTP binding protein. J Biol Chem 261: 7906–7911, 1986
    PubMed Google Scholar
34. Tsai S-C, Noda M, Adamik R, Moss J, Vaughan M: Enhancement of choleragen ADP-ribosyltransferase activities by guanyl nucleotides and a 19-kDa membrane protein. Proc Natl Acad Sci USA 84: 5139–5142, 1987
    PubMed Google Scholar
35. Tsai S-C, Noda M, Adamik R, Chang PP, Chen H-C, Moss J, Vaughan M: Stimulation of choleragen enzymatic activities by GTP and two soluble proteins purified from bovine brain. J Biol Chem 263: 1768–1772, 1988
    PubMed Google Scholar
36. Noda M, Tsai S-C, Adamik R, Moss J, Vaughan M: Mechanism of cholera toxin activation by a guanine nucleotide-dependent 19 kDa protein. Biochim Biophys Acta 1034: 195–199, 1990
    PubMed Google Scholar
37. Bobak DA, Blizotes MM, Noda M, Tsai S-C, Adamik R, Moss J: Mechanism of activation of cholera toxin by ADP-ribosylation factor (ARF): Both low- and high-affinity interactions of ARF with guanine nucleotides promote toxin activation. Biochemistry 29: 855–861, 1990
    PubMed Google Scholar
38. Tsai S-C, Adamik R, Moss J, Vaughan M: Guanine nucleotide dependent formation of a complex between choleragen (cholera toxin) A subunit and bovine brain ADP-ribosylation factor. Biochemistry 30: 3697–3703, 1991
    PubMed Google Scholar
39. Weiss O, Holden J, Rulka C, Kahn RA: Nucleotide binding and cofactor activities of purified bovine brain and bacterially expressed ADPribosylation factor. J Biol Chem 264: 21066–21072, 1989
    PubMed Google Scholar
40. Kahn RA, Kern FG, Clark J, Gelmann EP, Rulka C: Human ADP-ribosylation factors. A functionally conserved family of GTP-binding proteins. J Biol Chem 266: 2606–2614, 1991
    PubMed Google Scholar
41. Price SR, Welsh CF, Haun RS, Stanley SJ, Moss J, Vaughan M: Effects of phospholipid and GTP on recombinant ADP-ribosylation factors (ARFs). Molecular basis for differences in requirements for activity of mammalian ARFs. J Biol Chem 267: 17766–17772, 1992
    PubMed Google Scholar
42. Tsai S-C, Adamik R, Tsuchiya M, Chang PP, Moss J, Vaughan M: Differential expression during development of ADP-ribosylation factors, 20-kDa guanine nucleotide-binding protein activators of cholera toxin. J Biol Chem 266: 8213–8219, 1991
    PubMed Google Scholar
43. Mishima K, Price SR, Nightingale MS, Kousvelari E, Moss J, Vaughan M: Regulation of ADP-ribosylation factor (ARF) expression. Crossspecies conservation of the developmental and tissue-specific alternative polyadenylation of ARF 4 mRNA. J Biol Chem 267: 24109–24116, 1992
    PubMed Google Scholar
44. Sewell JL, Kahn RA: Sequences of the bovine and yeast ADP-ribosylation factor and comparison to other GTP-binding proteins. Proc Natl Acad Sci USA 85: 4620–4624, 1988
    PubMed Google Scholar
45. Bobak DA, Nightingale MS, Murtagh JJ, Price SR, Moss J, Vaughan M: Molecular cloning, characterization, and expression of human ADP-ribosylation factors: two guanine nucleotide-dependent activators of cholera toxin. Proc Natl Acad Sci USA 86: 6101–6105, 1989
    PubMed Google Scholar
46. Price SR, Nightingale MS, Tsai S-C, Williamson KC, Adamik R, Chen H-C, Moss J, Vaughan M: Guanine nucleotide-binding proteins that enhance choleragen ADP-ribosyltransferase activity: nucleotide and deduced amino acid sequence of an ADP-ribosylation factor cDNA. Proc Natl Acad Sci USA 85: 5488–5491, 1988
    PubMed Google Scholar
47. Monaco L, Murtagh JJ, Newman KB, Tsai S-C, Moss J, Vaughan M: Selective amplification of an mRNA and related pseudogene for a human ADP-ribosylation factor, a guanine nucleotide-dependent protein activator of cholera toxin. Proc Natl Acad Sci USA 87: 2206–2210, 1990
    PubMed Google Scholar
48. Tsuchiya M, Price SR, Tsai S-C, Moss J, Vaughan M: Molecular identification of ADP-ribosylation factor mRNAs and their expression in mammalian cells. J Biol Chem 266: 2772–2777, 1991
    PubMed Google Scholar
49. Peng Z, Calvert I, Clark J, Helman L, Kahn R, Kung H-F: Molecular cloning sequence analysis and mRNA expression of human ADP-ribosylation factor. Biofactors 2: 45–49, 1989
    PubMed Google Scholar
50. Stearns T, Kahn RA, Botstein D, Hoyt MA: ADP-ribosylation factor is an essential protein in_Saccharomyces cerevisiae_ and is encoded by two genes. Mol Cell Biol 10: 6690–6699, 1990
    PubMed Google Scholar
51. Murtagh JJ Jr, Lee F-JS, Deak P, Hall LM, Monaco L, Lee C-M, Stevens LA, Moss J, Vaughan M: Molecular, characterization of a conserved, guanine nucleotide-dependent ADP-ribosylation factor in_Drosophila melanogaster_. Biochemistry, 31: 6011–6018, 1993
    Google Scholar
52. Murtagh JJ Jr, Mowatt MR, Lee C-M, Lee F-JS, Mishima K, Nash TE, Moss J, Vaughan M: Guanine nucleotide-binding proteins in the intestinal parasite_Giardia lamblia_. Isolation of a gene encoding an ∼20 kDa ADP-ribosylation factor. J Biol Chem 267: 9654–9662, 1992
    PubMed Google Scholar
53. Tsuchiya M, Price SR, Nightingale MS, Moss J, Vaughan M: Tissues and species distribution of mRNA encoding two ADP-ribosylation factors, 20-kDa guanine nucleotide binding proteins. Biochemistry 28: 9668–9673, 1989
    PubMed Google Scholar
54. Tsai S-C, Haun RS, Tsuchiya M, Moss J, Vaughan M: Isolation and characterization of the human gene for ADP-ribosylation factor 3, a 20-kDa guanine nucleotide-binding protein activator of cholera toxin. J Biol Chem 266: 23053–23059, 1991
    PubMed Google Scholar
55. Lee C-M, Haun RS, Tsai S-C, Moss J, Vaughan M: Characterization of the human gene encoding ADP-ribosylation factor 1, a guanine nucleotide-binding activator of cholera toxin. J Biol Chem 267: 9028–9034, 1992
    PubMed Google Scholar
56. Serventi IM, Cavanaugh E, Moss J, Vaughan M: Characterization of the gene for ADP-ribosylation factor (ARF) 2, developmentally regulated, selectively expressed member of the ARF family of ∼20-kDa guanine nucleotide-binding proteins. J Biol Chem 268: 4863–4864, 1993
    PubMed Google Scholar
57. Haun RS, Moss J, Vaughan M: Characterization of the human ADP-ribosylation factor 3 promoter. Transcriptional regulation of a TATA-less promoter. J Biol Chem 268: 8793–8800, 1993
    PubMed Google Scholar
58. Price SR, Barber A, Moss J: Structure-function relationships of guanine nucleotide-binding proteins. In: J. Moss and M. Vaughan (eds). ADP-ribosylating Toxins and G Proteins: Instights Into Signal Transduction, American Society for Microbiology, Washington, DC, 1990, pp 397–424
    Google Scholar
59. Gibbs JB, Sigal IS, Poe M, Scolnick EM: Intrinsic GTPase activity distinguishes normal and oncogenic_ras_ p21 molecules. Proc Natl Acad Sci USA 81: 5704–5708, 1984
    PubMed Google Scholar
60. McGrath JP, Capon DJ, Goeddel DV, Levinson AD: Comparative biochemical properties of normal and activated human_ras_ p21 protein. Nature 310: 644–649, 1984
    PubMed Google Scholar
61. Sweet RW, Yokoyama S, Kamata T, Feramisco JR, Rosenberg M, Gross M: The product of_ras_ is a GTPase and the T24 oncogenic mutant is deficient in this activity. Nature 311: 273–275, 1984
    PubMed Google Scholar
62. Tamkun JW, Kahn RA, Kissinger M, Brizuela BJ, Rulka C, Scott MP, Kennison JA: The arflike gene encodes an essential GTP-binding protein in_Drosophila_. Proc Natl Acad Sci USA 88: 3120–3124, 1991
    PubMed Google Scholar
63. Haun RS, Tsai S-C, Adamik R, Moss J, Vaughan M: Effect of myristoylation on GTP-dependent binding of ADP-ribosylation factor to Golgi. J Biol Chem 268: 7064–7068, 1993
    PubMed Google Scholar
64. Kahn RA, Goddard C, Newkirk M: Chemical and immunological characterization of the 210kDaADP-ribosylation factor of adenylate cyclase. J Biol Chem 263: 8282–8287, 1988
    PubMed Google Scholar
65. Kunz BC, Muczynski KA, Welsh CF, Stanley SJ, Tsai S-C, Adamik R, Chang PP, Moss J, Vaughan M: Characterization of recombinant and endogenous ADP-ribosylation factors synthesized in Sf9 insect cells. Biochemistry 32: 6643–6648, 1993
    PubMed Google Scholar
66. Towler DA, Adams SP, Eubanks SR, Towery DS, Jackson-Machelski E, Glaser L, Gordon JI: Purification and characterization of yeast myristoyl CoA: protein N-myristoyltransferase. Proc Natl Acad Sci USA 84: 2708–2712, 1987
    PubMed Google Scholar
67. Kahn RA, Randazzo P, Serafini T, Weiss O, Rulka C, Clark J, Amherdt M, Roller P, Orci L, Rothman JE: The amino terminus of ADP-ribosylation factor (ARF) is a critical determinant of ARF activities and is a potent and specific inhibitor of protein transport. J Biol Chem 267: 13039–13046, 1992
    PubMed Google Scholar
68. Mishima K, Tsuchiya M, Nightingale MS, Moss J, Vaughan M: ARD 1, a 64-kDa guanine nucleotide-binding protein with a carboxyl-terminal ADR-ribosylation factor domain. J Biol Chem 268: 8801–8807, 1993
    PubMed Google Scholar
69. Stearns T, Willingham MC, Botstein D, Kahn RA: ADP-ribosylation factor is functionally and physically associated with the Golgi complex. Proc Natl Acad Sci USA 87: 1238–1242, 1990
    PubMed Google Scholar
70. Regazzi R, Ullrich S, Kahn RA, Wollheim CB: Redistribution of ADP-ribosylation factor during stimulation of permeabilized cells with GTP analogues. Biochem J 275: 639–644, 1991
    PubMed Google Scholar
71. Walker MW, Bobak DA, Tsai S-C, Moss J, Vaughan M: GTP but not GDP analogues promote association of ADP-ribosylation factors, 20-kDa protein activators of cholera toxin, with phospholipids and PC-12 cell membranes. J Biol Chem 267: 3230–3235, 1992
    PubMed Google Scholar
72. Donaldson JG, Kahn RA, Lippincott-Schwartz J, Klausner RD: Binding of ARF and β-COP to Golgi membranes: Possible regulation by a trimeric G protein. Science 254: 1197–1199, 1991
    PubMed Google Scholar
73. Lippincott-Schwartz J, Yuan LC, Bonifacino JS, Klausner RD: Rapid redistribution of Golgi proteins into the ER in cells treated with Brefeldin A: evidence for membrane cycling from Golgi to ER. Cell 56: 801–813, 1989
    PubMed Google Scholar
74. Lippincott-Schwartz J, Donaldson JG, Schweizer A, Berger EG, Hauri H-P, Yuan LC, Klausner RD: Microtubule-dependent retrograde transport of proteins into the ER in the presence of Brefeldin A suggests an ER recycling pathway. Cell 60: 821–836, 1990
    PubMed Google Scholar
75. Serafini T, Orci L, Amherdt M, Brunner M, Kahn RA, Rothman JE: ADP-ribosylation factor is a subunit of the coat of Golgi-derived COP-coated vesicles: a novel role for a GTP-binding protein. Cell 67: 239–253, 1991
    PubMed Google Scholar
76. Donaldson JG, Cassel D, Kahn RA, Klausner RD: ADP-ribosylation factor, a small GTP-binding protein, is required for binding of the coatomer protein β-COP to Golgi membranes. Proc Natl Acad Sci USA 89: 6408–6412, 1992
    PubMed Google Scholar
77. Donaldson JG, Finazzi D, Klausner RD: Brefeldin A inhibits Golgi membrane-catalysed exchange of guanine nucleotide onto ARF protein. Nature 360: 350–352, 1992
    PubMed Google Scholar
78. Helms JB, Rothman JE: Inhibition by brefeldin A of a Golgi membrane enzyme that catalyses exchange of guanine nucleotide bound to ARF. Nature 360: 352–354, 1992
    PubMed Google Scholar
79. Tsai S-C, Adamik R, Haun RS, Moss J, Vaughan M: Differential interaction of ADP-ribosylation factors 1, 3, and 5 with rat brain Golgi membranes. Proc Natl Acad Sci USA 89: 9272–9276, 1992
    PubMed Google Scholar
80. Tsai S-C, Adamik R, Haun RS, Moss J, Vaughan M: Effects of brefeldin A and accessory proteins on association of ADP-ribosylation factors 1, 3, and 5 with Golgi. J Biol Chem 268: 10820–10825, 1993
    PubMed Google Scholar
81. Balch WE, Kahn RA, Schwaninger R: ADP-ribosylation factor is required for vesicular trafficking between the endoplasmic reticulum and the_cis_-Golgi compartments. J Biol Chem 267: 13053–13061, 1992
    PubMed Google Scholar
82. Lenhard JM, Kahn RA, Stahl PD: Evidence for ADP-ribosylation factor (ARF) as a regulator of_in vitro_ endosome-endosome fusion. J Biol Chem 267: 13047–13052, 1992
    PubMed Google Scholar
83. Boman AL, Taylor TC, Melançon P, Wilson KL: A role for ADP-ribosylation factor in nuclear vesicle dynamics. Nature 358: 512–514, 1992
    PubMed Google Scholar

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