Pentachlorophenol measurements in body fluids of people in log homes and workplaces (original) (raw)
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Abstract
Human exposure to pentachlorophenol (PCP) was evaluated in the normal population (controls), residents of PCP-treated log homes, and persons exposed primarily in the workplace. Blood and urine samples were analyzed by gas chromatography after extraction and acetylation. For 34 controls, serum PCP values ranged from 15–75 ppb with a mean of 40 ppb. For 123 residents of log homes, serum levels ranged from 69–1,340 ppb with a mean of 420 ppb. In such homes, serum levels for children were significantly higher than those for parents, averaging 1.8 times greater. Serum and urine values for workers varied widely, depending on the workplace, with serum levels ranging from 26 to 84,900 ppb of PCP. Urinary concentrations when corrected for creatinine values correlated well (r=0.92) with serum concentrations. Coating PCP-treated logs of home interiors with a sealant reduced serum PCP levels in the residents.
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Authors and Affiliations
- Center for Environmental Health and Injury Control, Centers for Disease Control, Public Health Service, U.S. Department of Health and Human Services, 30333, Atlanta, Georgia, USA
Richard E. Cline, Robert H. Hill Jr., Donald L. Phillips & Larry L. Needham
Authors
- Richard E. Cline
You can also search for this author inPubMed Google Scholar - Robert H. Hill Jr.
You can also search for this author inPubMed Google Scholar - Donald L. Phillips
You can also search for this author inPubMed Google Scholar - Larry L. Needham
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Use of trade names is for identification only and does not constitute endorsement by the Public Health Service or the U.S. Department of Health and Human Services.
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Cline, R.E., Hill, R.H., Phillips, D.L. et al. Pentachlorophenol measurements in body fluids of people in log homes and workplaces.Arch. Environ. Contam. Toxicol. 18, 475–481 (1989). https://doi.org/10.1007/BF01055012
- Received: 07 November 1987
- Revised: 01 February 1988
- Issue Date: July 1989
- DOI: https://doi.org/10.1007/BF01055012