Insulin and glucagon concentrations in portal and peripheral veins in patients with hepatic cirrhosis (original) (raw)

References

  1. Assan, R.: In vivo metabolism of glucagon. In: Glucagon. Molecular, physiology, clinical and therapeutic implications. Lefebvre, P. J., Unger, R. H. (Eds.), pp. 47–59. Oxford: Pergamon 1972
    Google Scholar
  2. Berkowitz, D.: Glucose tolerance, free fatty acid, and serum insulin responses in patients with cirrhosis. Am. J. Dig. Dis.14, 691–699 (1969)
    Google Scholar
  3. Bittner, R., Beger, H. G., Kraas, E.: Oscillation in insulin response to glucose stimulation. Measurements in the portal vein in the postoperative period. Horm. Metab. Res.6, 423–424 (1974)
    Google Scholar
  4. Blackard, W. G., Rubenstein, A. H.: Proinsulin, insulin and Cpeptide concentrations in human portal and peripheral blood. J. Clin. Invest.55, 1278–1283 (1975)
    Google Scholar
  5. Cerasi, E., Hallberg, D., Luft, R.: Simultaneous determination of insulin in brachial and portal veins during glucose infusion in normal and prediabetic subjects. Horm. Metab. Res.2, 303–304 (1970)
    Google Scholar
  6. Collins, J. R., Crofford, O. B.: Glucose intolerance and insulin resistance in patients with liver disease. Arch. Intern. Med.124, 142–148 (1969)
    Google Scholar
  7. Conard, V.: Mesure de l'assimilation du glucose; bases théoriques et applications cliniques. Acta Gastroenterol. Belg.18, 655–705 (1955)
    Google Scholar
  8. Creutzfeldt, W., Frerichs, H., Kraft, W.: The intravenous tolbutamide test in liver disease. Acta Diabetol. Lat.4 [Suppl. 1], 209–230 (1967)
    Google Scholar
  9. Duprey, J., Lubetzki, J., Warnet, A.: Étude de la tolérance au glucose, de l'insuline-sécrétion et de la sensibilité a l'insuline endogène au cours des affections alcooliques du foie. Diabète22, 143–149 (1974)
    Google Scholar
  10. Efendic, S., Cerasi, E., Luft, R.: Quantitative study on the potentiating effect of arginine on glucose-induced insulin response in healthy, prediabetic, and diabetic subjects. Diabetes23, 161–171 (1974)
    Google Scholar
  11. Erwald, R., Hed, R., Nygren, A., Rojdmark, S., Sundblad, L., Wiechel, K. L.: Immunoreactive insulin in the portal and the peripheral venous blood after intravenous tolbutamide administration. Diabetes20, 686–690 (1971)
    Google Scholar
  12. Felber, J. P., Magnenat, P., Vannotti, A.: Tolèrance au glucose diminuée et réponse insulinique élevée dans la cirrhose. Schweiz. Med. Wochenschr.97, 1537–1539 (1967)
    Google Scholar
  13. Franckson, J. R. M., Ooms, H. A.: The catabolism of insulin in the dog: evidence for two catabolic pathways. Postgrad. Med. J.49, 931–939 (1974)
    Google Scholar
  14. Greco, A. V., Ghirlanda, G., Patrono, C., Fedeli, G., Manna, R.: Behavior of pancreatic glucagon, insulin and HGH in liver cirrhosis after arginine and i.v. glucose. Acta Diabetol. Lat.11, 330–339 (1974)
    Google Scholar
  15. Herbert, V., Lau, K. S., Gottlieb, C. W., Bleicher, S. J.: Coated charcoal immunoassay of insulin. J. Clin. Endocrinol. Metab.25, 1375–1384 (1965)
    Google Scholar
  16. Hernandez, A., Zorrilla, E., Gershberg, H.: Decreased insulin production, elevated growth hormone levels and glucose intolerance in liver disease. J. Lab. Clin. Med.73, 25–33 (1969)
    Google Scholar
  17. Jaspan, J. B., Huen, A. H. J., Morley, C. G., Moosa, A. R., Rubenstein, A. H.: The role of the liver in glucagon metabolism. J. Clin. Invest.60, 421–428 (1977)
    Google Scholar
  18. Johnston, D. G., Alberti, K. G. M. M., Faber, O. K., Binder, C., Wright, R.: Hyperinsulinism of hepatic cirrhosis: diminished degradation or hypersecretion? Lancet1977 I, 10–12
    Google Scholar
  19. Johnston, D. G., Alberti, K. G. M. M., Wright, R., Smith-Laing, G., Stewart, A. M., Sherlock, S., Faber, O., Binder, C.: C-peptide and insulin in liver disease. Diabetes27 [Suppl. 1], 201–206 (1978)
    Google Scholar
  20. Kaden, M., Harding, P., Field, J. B.: Effect of intraduodenal glucose administration on hepatic extraction of insulin in the anesthetized dog. J. Clin. Invest.52, 2016–2028 (1973)
    Google Scholar
  21. Kakiuchi, S., Tomizawa, H.H.: Properties of a glucagondegrading enzyme of beef liver. J. Biol. Chem.239, 2160–2164 (1964)
    Google Scholar
  22. Kanazawa, Y., Kukuya, T., Ide, T., Kosaka, K.: Plasma insulin responses to glucose in femoral, hepatic, and pancreatic veins in dogs. Am. J. Physiol.211, 442–448 (1966)
    Google Scholar
  23. Kaplan, N., Madison, L. L.: Effect of endogenous insulin secretion on the magnitude of hepatic binding of labelled-insulin during a single transhepatic circulation in human subjects. Clin. Res.7, 248 (1959)
    Google Scholar
  24. Kasperska, T., Lawecki, J., Rogala, H., Czyzyk, A.: The behaviour of insulinaemia in patients with liver cirrhosis after intravenous administration of glucose, tolbutamide and glucagon. Diabetologia7, 391–394 (1971)
    Google Scholar
  25. Kraas, E., Bittner, R., Meves, M., Beger, H. G.: Insulinkon-zentrationen in Pfortaderblut des Menschen nach Glucose-Infusion. Klin. Wochenschr.52, 404–406 (1976)
    Google Scholar
  26. Lefebvre, P., Fischer, U., Jutzi, E., Hommel, H., Luyckx, A. S.: Rôle du foie dans la captation du glucagon endogène chez le chien anesthésié. Ann. Endocrinol. (Paris)39, 347–348 (1978)
    Google Scholar
  27. Lefebvre, P. J., Luyckx, A. S.: Effect of acute kidney exclusion of renal arteries on peripheral plasma glucagon levels and pancreatic glucagon production in the anesthetized dog. Metabolism24, 1169–1183 (1975)
    Google Scholar
  28. Lund, B., Schmidt, A., Deckert, T.: Portal and cubital serum insulin during oral, portal and cubital glucose tolerance tests. Acta Med. Scand.197, 275–281 (1975)
    Google Scholar
  29. Madison, L. L., Combes, B., Unger, R. H., Kaplan, N.: The relationship between the mechanism of action of the sulphonylureas and the secretion of insulin into the portal circulation. Ann. N.Y. Acad. Sci.74, 548–556 (1959)
    Google Scholar
  30. Marco, J., Diego, J., Villanueva, M. L., Diaz-Fierros, M., Valverde, I., Segovia, J. M.: Elevated plasma glucagon levels in cirrhosis of the liver. N. Engl. J. Med.289, 1107–1111 (1973)
    Google Scholar
  31. Megyesi, C., Samols, E., Marks, V.: Glucose tolerance and diabetes in chronic liver disease. Lancet1967 II, 1051–1055
    Google Scholar
  32. Mondon, C. E., Olefsky, J. M., Dolkas, C. B., Reaven, G. M.: Removal of insulin by perfused rat liver: effect of concentration. Metabolism24, 153–160 (1975)
    Google Scholar
  33. Mortimer, G. E., Tietze, F., Stetten, D.: Metabolism of insu-lin-I131, studies in isolated, perfused rat liver and hind limb preparations. Diabetes8, 307–314 (1959)
    Google Scholar
  34. Rayfield, E. J., Faulkner, R. T., Czajkowski, W.: Portal and peripheral vein insulin responses to intravenous glucose in the rhesus monkey. J. Lab. Clin. Med.87, 919–924 (1976)
    Google Scholar
  35. Record, C. O., Alberti, K. G. M. M., Williamson, D. H., Wright, R.: Glucose tolerance and metabolic changes in human viral hepatitis. Clin. Sci. Mol. Med.45, 677–690 (1973)
    Google Scholar
  36. Röjdmark, S., Bloom, G., Chou, M. C. Y., Field, J. B.: Hepatic extraction of exogenous insulin and glucagon in the dog. Endocrinology102, 806–813 (1978)
    Google Scholar
  37. Samaan, N. A., Stone, D. B., Eckhardt, R. D.: Serum glucose, insulin and growth hormone in chronic hepatic cirrhosis. Arch. Intern. Med.124, 149–152 (1969)
    Google Scholar
  38. Samols, E., Ryder, J. A.: Studied on tissue uptake of insulin in man using differential immunoassay for endogenous and exogenous insulin. J. Clin. Invest.40, 2092–2102 (1961)
    Google Scholar
  39. Sherwin, R. S., Bastl, C., Finkelstein, F. O., Fisher, M., Black, H., Hendler, R., Felig, P.: Influence of uremia and hemodialysis on the turnover and metabolic effects of glucagon. J. Clin. Invest.57, 722–731 (1976)
    Google Scholar
  40. Sherwin, R. S., Fisher, M., Bessoff, J., Snyder, N., Hendler, R., Conn, H. O., Felig, P.: Hyperglucagonemia in cirrhosis: altered secretion and sensitivity to glucagon. Gastroenterology74, 1224–1228 (1978)
    Google Scholar
  41. Sherwin, R., Joshi, P., Hendler, R., Felig, P., Conn, H. O.: Hyperglucagonemia in Laennec's cirrhosis. N. Engl. J. Med.290, 239–242 (1974)
    Google Scholar
  42. Shurberg, J. L., Resnick, R. H., Koff, R. S., Ross, E., Baum, R. A., Pallotta, J. A.: Serum lipids, insulin and glucagon after portacaval shunt in cirrhosis. Gastroenterology72, 301–304 (1977)
    Google Scholar
  43. Unger, R. H., Eisentraut, A. M., McCall, M. S., Madison, L. L.: Measurements of endogenous glucagon in plasma and the influence of blood glucose concentration upon its secretion. J. Clin. Invest.41, 682–689 (1962)
    Google Scholar

Download references