Regression of Barrett's esophagus by laser ablation in an anacid environment (original) (raw)

Summary

Consistent regression of intestinal metaplasia in Barrett's esophagus has not been achieved with medical or surgical interventions. In this case report, a patient with Barrett's esophagus of stable length had half the circumference of the Barrett's epithelium ablated with laser therapy while on a high-dose proton-pump inhibitor. In the absence of esophageal acid exposure and after laser ablation, the intestinal metaplasia was documented to reepithelialize with normal squamous mucosa, which has oersisted.

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Authors and Affiliations

1. Department of Internal Medicine, Sections of Gastroenterology and Hematology-Oncology, University of Arizona Health Sciences Center, Tucson, Arizona
   Richard E. Sampliner MD, Lee J. Hixson MD, M. Brian Fennerty MD & Harinder S. Garewal MD, PhD
2. Tucson Veterans Affairs Medical Center, 3601 S 6th Avenue, 85723, Tucson, Arizona
   Richard E. Sampliner MD, Lee J. Hixson MD, M. Brian Fennerty MD & Harinder S. Garewal MD, PhD

Authors

1. Richard E. Sampliner MD
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2. Lee J. Hixson MD
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3. M. Brian Fennerty MD
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4. Harinder S. Garewal MD, PhD
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Sampliner, R.E., Hixson, L.J., Fennerty, M.B. et al. Regression of Barrett's esophagus by laser ablation in an anacid environment.Digest Dis Sci 38, 365–368 (1993). https://doi.org/10.1007/BF01307557

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• Received: 27 November 1991
• Revised: 23 March 1992
• Accepted: 23 March 1992
• Issue Date: February 1993
• DOI: https://doi.org/10.1007/BF01307557

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