Loss in expression of the retinoblastoma gene product in human gliomas is associated with advanced disease (original) (raw)
References
Horowitz JM, Park S-H, Bogenmann E, Cheng J-C, Yandell DW, Kaye FJ, Minna JD, Dryja TP, Weinberg RA: Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumor cells. Proc Natl Acad Sci USA 87: 2775–2779, 1990 Google Scholar
Friend SH, Horowitz JM, Gerber MR, Wang X-F, Bogenmann E, Li FP, Weinberg RA: Deletions of a DNA sequence in retinoblastoma and mesenchymal tumors: organization of the sequence and its encoded protein. Proc Natl Acad Sci USA 84: 9059–9063, 1987 Google Scholar
Shew J-Y, Ling N, Yang X, Fodstad O, Lee W-H: Antibodies detecting abnormalities of the retinoblastoma susceptibility gene product (p110RB) in osteosarcomas and synovial sarcomas. Oncogene Res 1: 205–214, 1989 Google Scholar
Cance WG, Brennan MF, Dudas ME, Huang C-M, Cordon-Cardo CN: Altered expression of the retinoblastoma gene product in human sarcomas. Engl J Med 323: 1457–1462, 1990 Google Scholar
Yokota J, Akiyama T, Fung Y-KT, Benedict WF, Namba Y, Hanaoka M, Wada M, Terasaki T, Shimosato Y, Sugimura T, Terada M: Altered expression of the retinoblastoma (RB) gene in small-cell carcinoma of the lung. Oncogene 3: 471–475, 1988 Google Scholar
Hensel CH, Hsieh C-L, Gazdar AF, Johnson BE, Sakaguchi AY, Naylor SL, Lee W-H, Lee EY-HP: Altered structure and expression of the human retinoblastoma susceptibility gene in small cell lung cancer. Cancer Res 50: 3067–3072, 1990 Google Scholar
Mori N, Yokota J, Akiyama T, Sameshima Y, Okamoto A, Mizoguchi H, Toyoshima K, Sugimura T, Terada M: Variable mutations of the RB gene in small-cell lung carcinoma. Oncogene 5: 1713–1717, 1990 Google Scholar
Rygaard K, Sorenson GD, Pettengill OS, Cate CC, Spang-Thomsen M: Abnormalities in structure and expression of the retinoblastoma gene in small cell lung cancer cell lines and xenografts in nude mice. Cancer Res 50: 5312–5317, 1990 Google Scholar
Lee EY-HP, To H, Shew Y-Y, Bookstein R, Scully P, Lee W-H: Inactivation of the retinoblastoma susceptibility gene in human breast cancers. Science 241: 218–221, 1988 Google Scholar
Harbour JW, Lai S-L, Whang-Peng J, Gazdar AF, Minna JD, Kaye FJ: Abnormalities in structure and expression of the human retinoblastoma gene in SCLC. Science 241: 353–357, 1988 Google Scholar
T'Ang A, Varley JM, Chakraborty S, Murphree AL, Fung Y-KT: Structural rearrangement of the retinoblastoma gene in human breast carcinoma. Science 242: 263–266, 1988 Google Scholar
Varley JM, Armour J, Swallow JE, Jeffreys AJ, Ponde BAJ, T'Ang A, Fung Y-KT, Brammar WJ, Walker RA: The retinoblastoma gene is frequently altered leading to loss of expression in primary breast tumours. Oncogene 4: 725–729, 1989 Google Scholar
Lee W-H, Bookstein R, Hong F, Young L-J, Shew J-Y, Lee EY-HP: Human retinoblastoma susceptibility gene: cloning, identification, and sequence. Science 235: 1394–1399, 1987 Google Scholar
Horowitz JM, Yandell DW, Park S-H, Canning S, Whyte P, Buchkovich K, Harlow E, Weinberg RA, Dryja TP: Point mutational inactivation of the retinoblastoma antioncogene. Science 243: 937–940, 1989 Google Scholar
Draper GJ, Sanders BM, Kingston JE: Second primary neoplasms in patients with retinoblastoma. Br J Cancer 53: 661–671, 1986 Google Scholar
Mittelman F: Catalog of Chromosome Aberrations in Cancer (3rd Edition). Alan R Liss, New York, 1988, pp 589–590 Google Scholar
James CD, Carlbom E, Dumanski JP, Hansen M, Nordenskjold M, Collins VP, Cavanee WK: Clonal genomic alterations in glioma malignancy stages. Cancer Res 48: 5546–5551, 1988 Google Scholar
Venter DJ, Bevan KL, Ludwig RL, Riley TEW, Jat PS, Thomas DGT, Noble MD: Retinoblastoma gene deletions in human gliomas. Oncogene 6: 445–448, 1990 Google Scholar
Westphal M, Haensel M, Nausch H, Rohde E, Herrmann H-D: Culture of human brain tumors on an extracellular matrix derived from bovine corneal endothelial cells and cultured human glioma cells. In: Pollard JW, Walker JM (eds) Methods in Molecular Biology (5): Animal Cell Culture, Humana Press, Clifton, New Jersey, 1990, pp 113–131 Google Scholar
Chomczyinski P, Sacchi N: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162: 156–159, 1987 Google Scholar
Hamel W, Westphal M, Shepard HM: Proto-oncogene expression in human glioma derived cell lines. Int J Oncol 1: 673–682, 1992 Google Scholar
Hamel W, Westphal M, Szonyi E, Escandon E, Nikolics K: Neurotrophin gene expression by cell lines derived from human gliomas. J Neurosci Res 34: 147–157, 1993 Google Scholar
Xu H-J, Hu S-X, Benedict WF: Lack of nuclear RB protein staining in GO/middle G1 cells: correlation to changes in total RB protein level. Oncogene 6: 1139–1146, 1991 Google Scholar
Sidransky D, Mikkelsen T, Schwechheimer K, Rosenblum ML, Cavenee WK, Vogelstein B: Clonal expansion of p53 mutant cells is associated with brain tumor progression. Nature 355: 846–847, 1992 Google Scholar
Xu H-J, Hu S-X, Hashimoto T, Takahashi R, Benedict WF: The retinoblastoma susceptibility gene product: a characteristic pattern in normal cells and abnormal expression in malignant cells. Oncogene 4: 807–812, 1989 Google Scholar