Reduced [3H]flunitrazepam binding in cingulate cortex and hippocampus of postmortem schizophrenic brains: Is selective loss of glutamatergic neurons associated with major psychoses? (original) (raw)
References
Brown, R., Colter, N., Corsellis, J. A. N., Crow, T. J., Frith, C. D., Jagoe, R., Johnstone, E. C., and Marsh, L., 1986. Postmortem evidence of structural brain changes in schizophrenia. Arch. Gen. Psychiat. 43:36–42. Google Scholar
Jest, D. V., Lohr, J. B., and Goodwin, F. K. 1988. Neuroanatomical studies of major affective dissorders. Brit. J. Psychiat. 153:444–459. Google Scholar
Kelsoe, J. R., Jr., L. Cadet, J., Pickar, D., and Weinberger, D. R. 1988. Quantitative neuroanatomy in schizophrenia. Arch. Gen. Psychiat. 45:533–541. Google Scholar
Suddath, R. L., Christison, G. W., Torrey, E. F., Casanova, M. F., and Weinberger, D. R. 1990. Anatomical abnormalities in the brains of monozygotic twins discordant for schizophrenia. N. Engl. J. Med. 322:789–794. Google Scholar
Roberts, G. W. 1991. Schizophrenia: A neuropathological perspective. Brit. J. Psychiat. 158:8–17. Google Scholar
Zipursky, R. B., Lim, K. O., Sullivan, E. V., Brown, B. W., and Pfefferbaum, A. 1992. Widespread cerebral gray matter volume deficits in schizophrenia. Arch. Gen Psychiat. 49:195–205. Google Scholar
Benes, F. M., Davidson, J., and Bird, E. D. 1986. Quantitative cytoarchitectural studies of the cerebral cortex of schizophrenics. Arch. Gen. Psychiat. 43:31–35. Google Scholar
Pakkenberg, B. 1990. Pronounced reduction of total neuron number in mediodorsal thalamic nucleus and nucleus accumbens in schizophrenics. Arch. Gen. Psychiat. 47:1023–1028. Google Scholar
Torrey, E. F. 1991. A viral-anatomical explanation of schizophrenia. Schizophrenia Bull. 17:15–18. Google Scholar
Benes, F. M., McSparren, J., Bird, E. D., SanGiovanni, J. P., and Vincent, S. L. 1991. Deficits in small interneurons in prefrontal and cingulate cortices of schizophrenics and schizoaffective patients. Arch. Gen. Psychiat. 48:996–1001. Google Scholar
Benes, F. M., Sorensen, I., and Bird, E. D. 1991. Reduced neuronal size in posterior hippocampus of schizophrenic patients. Schizophrenia Bull. 17:597–608. Google Scholar
King, D. J., and Cooper, S. J. 1989. Viruses, immunity and mental disorder. Brit. J. Psychiat. 154:1–7. Google Scholar
Ottersen, O. P., and Storm-Mathisen, J. 1985. Different neuronal localization of aspartate-like and glutamate-like immunoreactivitics in the hippocampus of rat, guinea-pig and senegalese baboon (Papio Papio), with a note on the distribution of γ-aminobutyrate. Neuroscience 16:589–606. Google Scholar
Kowall, N. W., and Beal, M. F. 1991. Glutamate-, glutaminase-, and taurine-immunoreactive neurons develop neurofibrillary tangles in Alzheimer's disease. Ann. Neurol. 29:162–167. Google Scholar
Squires, R. F., and Saederup, E. 1991. A review of evidence for GABAergic predominance/glutamatergic deficit as a common etiological factor in both schizophrenia and affective psychoses: more support for a continuum hypothesis of “functional” psychosis. Neurochem. Res. 16:1099–1111. Google Scholar
Young, A. B., Oster-Granite, M. L., Herndon R. M., and Snyder, S. H. 1974. Glutamic acid: selective depletion by viral induced granule cell loss in hamster cerebellum. Brain Res. 73:1–13. Google Scholar
Herndon, R. M., Margolis, G., and Kilham L. 1971. The synaptic organization of the malformed cerebellum induced by perinatal infection with the feline panleukopenia virus (PLV). J. neuropathol. Exp. Neurol. 30:196–205. Google Scholar
American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders, 3rd Edition, revised. Washington, D.C., American Psychiatric Association 1987. Google Scholar
Palkovits, M. 1973. Isolated removal of hypothalamic or other brain nuclei of the rat. Brain Res. 59:449–450. Google Scholar
Squires, R. F., and Saederup, E. 1982. γ-Aminobutyric acid receptors modualte cation binding sites coupled to independent benzodiazepine, picrotoxin, and anion binding sites. Mol. Pharmacol. 22:327–334. Google Scholar
Squires R. F., and Saederup, E. 1989. Polychlorinated convulsant insecticides potentiate the protective effect of NaCl against heat inactivation of [3H]flunitrazepam binding sites. J. Neurochem. 52:537–543. Google Scholar
Braestrup, C., and Squires, R. F. 1977. Specific benzodiazepine receptors in rat brain characterized by high-affinity [3H]diazepam binding. Proc. Natl. Acad. Sci. USA 74:3805–3809. Google Scholar
Braestrup, C., Albrechtsen, R., and Squires, R. F. 1977. High densities of benzodiazepine receptors in human cortical areas. Nature 269:702–704. Google Scholar
Young, W. S. III, and Kuhar, M. J. 1979. Radiohistochemical localization of benzodizepine receptors in rat brain. J. Pharmacol. Exp. Ther. 212:337–346. Google Scholar
Richards, J. G., Schoch, P., Haring, P., Takacs, B., and Mohler, H. 1987. Resolving GABAA/benzodiazepine receptors: cellular and subcellular localization in the CNS with monoclonal antibodies. J. Neurosci. 7:1866–1886. Google Scholar
Conti, F., Rustioni, A., Petrusz, P., and Towle, A. C. 1987. Glutamate-positive neurons in the somatic sensory cortex of rats and monkeys. J. Neursci. 7:1887–1901. Google Scholar
Ottersen, O. P., and Storm-Mathisen, J. 1984. Glutmate-and GABA-containing neurons in the mouse and rat brain, as demonstrated with a new immunocytochemical technique. J. Comp. Neurol. 229:374–392. Google Scholar
Braak, H. 1984. Architectonics as seen by lipofuscin stains. Pages 59–99,in Peters, A., Jones, E. G. (eds.) Cerebral Cortex Vol I, Plenum Press, New York. Google Scholar
Pritchett, D. B., Sontheimer, H., Shivers, B. D., Ymer, S., Kettenmann, H., Schofield, P. R., and Seeburg, P. H. 1989. Importance of a novel GABAA receptor subunit for benzodiazepine pharmacology, Nature 338:582–585. Google Scholar
Sequier, J. M., Richards, J. G., Malherbe, P., Price, G. W., Mathews, S., and Mohler, H. 1988. Mapping of brain areas containing RNA homologous to cDNAs encoding the α and β subunits of the rat GABAA γ-aminobutyrate receptor. Proc. Natl. Acad. Sci. 85:7815–7819. Google Scholar
Wisden, W., Laurie, D. J., Monyer, H., and Seeburg, P. H. 1992. The distribution of 13 GABAA receptor subunits mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalon. J. Neurosci. 12:1040–1062. Google Scholar
Herb, A., Wisden, W., Luddens, H., Puia, G., Vicini, S., and Seeburg, P. H. 1992. The third subunit of the γ-aminobutyric acid type A receptor family. Proc. Natl. Acad. Sci. 89:1433–1437. Google Scholar
Benes, F. M., Vicent, S. L., Alsterberg, G., Bird, E. D., and SanGiovanni, J. P. 1992. Increased GABAA receptor binding in superficial layers of cingulate cortex in schizophrenics. J. Neurosci. 12:924–929. Google Scholar
Benes, F. M., Majocha R., Bird, E. D., and Marotta, C. A. 1987. Increased vertical axon numbers in cingulate cortex of schizophrenics. Arch. Gen. Psychiat. 44:1017–1021. Google Scholar
Hanada, S., Mita, T., Nishino, N., and Tanaka, C. 1987. [3H]Muscimol binding sites increased in autopsied brains of chronic schizophrenics. Life Sci. 40:259–266. Google Scholar
Cross, A. J., Crow, T. J., and Owens, F. 1979. Gamma-aminobutyric acid in the brain schizophrenia. Lancet, March 10, 1979, pp. 560–561.
Wamsley, J. K., McCabe, R. T. and Gehlert, D. R. 1986. Autoradiographic localization of binding sites in several GABA and benzodiazepine receptor complexes. Pages 79–89, in Squires, R. F. (ed.), GABA and Benzodiazepine Receptors Vol I, CRC Press, Florida. Google Scholar
Bogerts, B., Meertz, E., and Schonfeldt-Bausch, R. 1985. Basal ganglia and limbic system pathology in schizophrenia. Arch. Gen. Psychiat. 42:784–791. Google Scholar
Stevens, J. R. 1988. Epilepsy, psychosis and schizophrenia. Schizophrenia Res. 1:79–89. Google Scholar