Is plasmid based differentiation ofCoxiella burnetii in ‘acute’ and ‘chronic’ isolates still valid? (original) (raw)

Abstract

Ten human_Coxiella burnetii_ isolates from french patients with acute hepatitis or chronic endocarditis were characterized according to their polymorphism in DNA restriction patterns and differentiated by plasmid-specific PCR. The aim of this investigation was to clarify if the present classification of so called ‘acute’ and ‘chronic’Coxiella burnetii isolates — based on plasmid profile of a so far limited number of partly ancient isolates — could be confirmed with lately isolated organisms of this agent. The data obtained in this investigation indicate that this classification based on_C. burnetii_ plasmid content is no longer justified.

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Authors and Affiliations

  1. Institut für Hygiene und Infektionskrankheiten der Tiere, Justus-Liebig-Universität Giessen, Frankfurter Str. 89, D-35392, Giessen, Germany
    D. Thiele & H. Willems

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  1. D. Thiele
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  2. H. Willems
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Thiele, D., Willems, H. Is plasmid based differentiation of_Coxiella burnetii_ in ‘acute’ and ‘chronic’ isolates still valid?.Eur J Epidemiol 10, 427–434 (1994). https://doi.org/10.1007/BF01719667

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