Somatostatin reduces the release of colony-stimulating activity (CSA) from PHA-activated mouse spleen lymphocytes (original) (raw)

We’re sorry, something doesn't seem to be working properly.

Please try refreshing the page. If that doesn't work, please contact support so we can address the problem.

Summary

PHA-activated lymphocytes release colony-stimulating activity (CSA) for macrophage-granulocyte precursor cells (colony forming units, CFUC) in the culture medium. Somatostatin, known to interfer with ribosomal protein synthesis, was demonstrated to reduce the release of CSA from PHA-treated mouse spleen lymphocytes.

Access this article

Log in via an institution

Subscribe and save

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Literatur

  1. D. Metcalf, J. Cell Physiol.76, 89 (1970).
    Google Scholar
  2. F. Ruscetti and P.A. Chervenick, J. Immun.114, 1513 (1975).
    Google Scholar
  3. A. Boyum, Scand. J. Lab. Invest.21, suppl., 97 (1968).
  4. H. Messner, J. Till and E. McCullough, Blood_44_, 671 (1974).
    Google Scholar
  5. D. Metcalf and M.A.S. Moore, in: Haemopoietic Cells, p. 35. North Holland Publ. Company, 1971.
  6. W. Hinterberger and W.R. Paukovits, IRCS_5_, 137 (1977).
    Google Scholar
  7. J.W. Parker and D. Metcalf, J. Immun.112, 502 (1974).
    Google Scholar
  8. P.R. Ogida, P.V.N. Murthy and J.M. McKenzie, Biochemistry_10_, 711 (1971).
    Google Scholar
  9. K.H. Tragl and H. Kinast, Klin. Wschr.55, 707 (1977).
    Google Scholar
  10. R. Hirschorn, in: Cyclic AMP, Cell growth and the Immune Response, p. 45. Ed. Braun, Lichtenstein & Parker. Springer, Berlin/Heidelberg/New York 1974.
    Google Scholar

Download references

Author information

Authors and Affiliations

  1. 1st Dept. of Medicine, University of Vienna, Lazarettgasse 14, A-1090, Wien, Austria
    W. Hinterberger, C. Cerny, H. Kinast, H. Pointner & K. H. Tragl

Authors

  1. W. Hinterberger
    You can also search for this author inPubMed Google Scholar
  2. C. Cerny
    You can also search for this author inPubMed Google Scholar
  3. H. Kinast
    You can also search for this author inPubMed Google Scholar
  4. H. Pointner
    You can also search for this author inPubMed Google Scholar
  5. K. H. Tragl
    You can also search for this author inPubMed Google Scholar

Additional information

The technical assistance of Ulrike Wallner and Paulette Bais is thankfully acknowledged.

Rights and permissions

About this article

Cite this article

Hinterberger, W., Cerny, C., Kinast, H. et al. Somatostatin reduces the release of colony-stimulating activity (CSA) from PHA-activated mouse spleen lymphocytes.Experientia 34, 860–862 (1978). https://doi.org/10.1007/BF01939667

Download citation

Keywords