The role of venous and neural invasion on survival in... : Diseases of the Colon & Rectum (original) (raw)

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The role of venous and neural invasion on survival in rectal adenocarcinoma

Horn, Arild M.D.1; Dahl, Olav M.D., PH.D.2; Morild, Inge M.D., Ph.D.3

1Department of Surgery, Haukeland Hospital

University of Bergen

N-5021

Bergen

Norway

2Department of Oncology, Haukeland Hospital

University of Bergen

Bergen

Norway

3Department of Pathology, Haukeland Hospital

University of Bergen

Bergen

Norway

Abstract

A total of 254 rectal adenocarcinomas were examined for the presence of venous and neural invasion. Both the incidence of venous and neural invasion increased with Astler-Coller's stage, except for stage Cl related to neural invasion. Both prognostic factors predicted significantly reduced actuarial survival rates in patients with nodenegative tumors. Thus, examination for the presence of venous and neural invasion can add information to conventional staging in nodenegative tumors for assessing prognosis after radical surgery for rectal adenocarcinoma.

© The ASCRS 1990

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