A change in the genetic code inMycoplasma capricolum (original) (raw)

Summary

Mycoplasma capricolum was previously found to use UGA instead of UGG as its codon for tryptophan and to contain 75%A+ T in its DNA. The codon change could have been due to mutational pressure to replace C+G by A+T, resulting in the replacement of UGA stop codons by UAA, change of the anticodon in tryptophan tRNA from CCA to UCA, and replacement of UGG tryptophan codons by UGA. None of these changes should have been deleterious.

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  1. Space Sciences Laboratory, University of California, 94720, Berkeley, California, USA
    Thomas H. Jukes

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  1. Thomas H. Jukes
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Jukes, T.H. A change in the genetic code in_Mycoplasma capricolum_.J Mol Evol 22, 361–362 (1985). https://doi.org/10.1007/BF02115692

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