Current status of cancer therapy with radiolabeled monoclonal antibody (original) (raw)
References
Kohler G, Milstein C. Continuous cultures of fused cells secreting antibody of predefined specificity.Nature 1975; 256:495–497. ArticlePubMedCAS Google Scholar
McLaughlin P, Grillo-Lopez AJ, Link BK, Levy R, Czuczman MS, Williams ME, et al. Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma: half of patients respond to a four-dose treatment program.J Clin Oncol 1998; 16:2825–2833. PubMedCAS Google Scholar
Reff ME, Carner K, Chambers KS, Chinn PC, Leonard JE, Raab R, et al. Depletion of B cells_in vivo_ by a chimeric mouse human monoclonal antibody to CD20.Blood 1994; 83:435–445. PubMedCAS Google Scholar
Shan D, Ledbetter JA, Press OW. Apoptosis of malignant human B cells by ligation of CD20 with monoclonal antibodies.Blood 1998; 91:1644–1652. PubMedCAS Google Scholar
Tutt AL, French RR, Illidge TM, Honeychurch J, McBride HM, Penfold CA, et al. Monoclonal antibody therapy of B cell lymphoma: signaling activity on tumor cells appears more important than recruitment of effectors.J Immunol 1998; 161:3176–3185. PubMedCAS Google Scholar
Baselga J, Mendelsohn J. The epidermal growth factor receptor as a target for therapy in breast carcinoma.Breast Cancer Res Treat 1994; 29:127–138. ArticlePubMedCAS Google Scholar
Ritter G, Cohen LS, Williams Jr C, Richards EC, Old LJ, Welt S. Serological Analysis of Human Anti-Human Antibody Responses in Colon Cancer Patients Treated with Repeated Doses of Humanized Monoclonal Antibody A33.Cancer Res 2001 ; 61:6851–6859. PubMedCAS Google Scholar
Tomizuka K, Shinohara T, Yoshida H, Uejima H, Ohguma A, Tanaka S, et al. Double trans-chromosomic mice: maintenance of two individual human chromosome fragments containing Ig heavy and kappa loci and expression of fully human antibodies.Proc Natl Acad Sci USA 2000; 97:722–727. ArticlePubMedCAS Google Scholar
Ishida I, Tomizuka K, Yoshida H, Tahara T, Takahashi N, Ohguma A, et al. Production of human monoclonal and polyclonal antibodies in TransChromo animals.Cloning Stem Cells 2002; 4:91–102. ArticlePubMedCAS Google Scholar
Winter G, Griffiths AD, Hawkins RE, Hoogenboom HR. Making antibodies by phage display technology.Annu Rev Immunol 1994; 12:33–455. Article Google Scholar
Tsurushita N, Park M, Pakabunto K, Ong K, Avdalovic A, Fu H, et al. Humanization of a chicken anti-IL-12 monoclonal antibody.J Immunol Methods 2004; 295:9–19. ArticlePubMedCAS Google Scholar
McDevitt MR, Sgouros G, Finn RD, Humm JL, Jurcic JG, Larson SM, et al. Radioimmunotherapy with alpha-emitting nuclides.Eur J Nucl Med 1998; 25:1341–1351. ArticlePubMedCAS Google Scholar
Macklis RM, Kinsey BM, Kassis AI, Ferrara JL, Atcher RW, Hines JJ, et al. Radioimmunotherapy with alpha-particle-emitting immunoconjugates.Science 1988; 240:1024–1026. ArticlePubMedCAS Google Scholar
Behr TM, Behe M, Lohr M, Sgouros G, Angerstein C, Wehrmann E, et al. Therapeutic advantages of Auger electron- over beta-emitting radiometals or radioiodine when conjugated to internalizing antibodies.Eur J Nucl Med 2000; 27:753–765. ArticlePubMedCAS Google Scholar
Burke JM, Jurcic JG, Scheinberg DA. Radioimmunotherapy for acute leukemia.Cancer Control 2002; 9:106–113. PubMed Google Scholar
Juweid M, Sharkey RM, Swayne LC, Griffiths GL, Dunn R, Goldenberg DM. Pharmacokinetics, dosimetry and toxicity of rhenium-188-labeled anti-carcinoembryonic antigen monoclonal antibody, MN-14, in gastrointestinal cancer.J Nucl Med 1998; 39:34–42. PubMedCAS Google Scholar
Behr TM, Sharkey RM, Juweid ME, Dunn RM, Vagg RC, Ying Z, et al. Phase I/II clinical radioimmunotherapy with an iodine-131-labeled anti-carcinoembryonic antigen murine monoclonal antibody IgG.J Nucl Med 1997; 38:858–870. PubMedCAS Google Scholar
Juweid ME, Sharkey RM, Behr T, Swayne LC, Dunn R, Siegel J, et al. Radioimmunotherapy of patients with small-volume tumors using iodine-131-labeled anti-CEA monoclonal antibody NP-4 F(ab’)2.J Nucl Med 1996; 37:1504–1510. PubMedCAS Google Scholar
Behr TM, Liersch T, Greiner-Bechert L, Griesinger F, Behe M, Markus PM, et al. Radioimmunotherapy of small-volume disease of metastatic colorectal cancer.Cancer 2002; 94(4 Suppl); 1373–1381. ArticlePubMedCAS Google Scholar
Wong JYC, Chu DZ, Yamauchi DM, Williams LE, Liu A, Wilczynski S, et al. A phase I radioimmunotherapy trial evaluating 90yttrium-labeled anti-carcinoembryonic antigen (CEA) chimeric T84.66 in patients with metastatic CEA-producing malignancies.Clin Cancer Res 2000; 6:3855–3863. PubMedCAS Google Scholar
Wu AM, Yazaki PJ, Tsai S, Nguyen K, Anderson AL, McCarthy DW, et al. High-resolution microPET imaging of carcinoembryonic antigen-positive xenografts by using a copper-64-labeled engineered antibody fragment.Proc Natl Acad Sci USA 2000; 97:8495–8500. ArticlePubMedCAS Google Scholar
Begent RH, Ledermann JA, Green AJ, Bagshawe KD, Riggs SJ, Searle F, et al. Antibody distribution and dosimetry in patients receiving radiolabelled antibody therapy for colorectal cancer.Br J Cancer 1989; 60:406–412. PubMedCAS Google Scholar
Begent RH, Verhaar MJ, Chester KA, Casey JL, Green AJ, Napier MP, et al. Clinical evidence of efficient tumor targeting based on single-chain Fv antibody selected from a combinatorial library.Nat Med 1996; 2:979–984. ArticlePubMedCAS Google Scholar
Wong JY, Shibata S, Williams LE, Kwok CS, Liu A, Chu DZ, et al. A Phase I trial of90Y-anti-carcinoembryonic antigen chimeric T84.66 radioimmunotherapy with 5-fluorouracil in patients with metastatic colorectal cancer.Clin Cancer Res 2003; 9:5842–5852. PubMedCAS Google Scholar
Murray JL, Macey DJ, Kasi LP, Rieger P, Cunningham J, Bhadkamkar V, et al. Phase II radioimmunotherapy trial with131I-CC49 in colorectal cancer.Cancer 1994; 73(suppl):1057–1066. ArticlePubMedCAS Google Scholar
Macey DJ, Grant EJ, Kasi L, Rosenblum MG, Zhang HZ, Katz RL, et al. Effect of recombinant alpha-interferon on pharmacokinetics, biodistribution, toxicity, and efficacy of131I-labeled monoclonal antibody CC49 in breast cancer: a phase II trial.Clin Cancer Res 1997; 3:1547–1555. PubMedCAS Google Scholar
Meredith RF, Khazaeli MB, Macey DJ, Grizzle WE, Mayo M, Schlom J, et al. Phase II study of interferon-enhanced131I-labeled high affinity CC49 monoclonal antibody therapy in patients with metastatic prostate cancer.Clin Cancer Res 1999; 5(suppl):3254s-3258s. PubMedCAS Google Scholar
Meredith RF, Khazaeli MB, Plott WE, Grizzle WE, Liu T, Schlom J, et al. Phase II study of dual131I-labeled monoclonal antibody therapy with interferon in patients with metastatic colorectal cancer.Clin Cancer Res 1996; 2:1811–1818. PubMedCAS Google Scholar
Meredith RF, Khazaeli MB, Plott WE, SA, Wheeler RH, Brady LW, et al. Initial clinical evaluation of iodine-125-labeled chimeric 17-1A for metastatic colon cancer.J Nucl Med 1995; 36:2229–2233. PubMedCAS Google Scholar
Daghighian F, Barendswaard E, Welt S, Humm J, Scott A, Willingham MC, et al. Enhancement of radiation dose to the nucleus by vesicular internalization of iodine-125-labeled A33 monoclonal antibody.J Nucl Med 1996; 37:1052–1057. PubMedCAS Google Scholar
Welt S, Scott AM, Divgi CR, Kemeny NE, Finn RD, Daghighian F, et al. Phase I/II study of iodine 125-labeled monoclonal antibody A33 in patients with advanced colon cancer.J Clin Oncol 1996; 14:1787–1797. PubMedCAS Google Scholar
Alvarez RD, Partridge EE, Khazaeli MB, Plott G, Austin M, Kilgore L, et al. Intraperitoneal radioimmunotherapy of ovarian cancer with177Lu-CC49: a phase I/II study.Gynecol Oncol 1997; 65:94–101. ArticlePubMedCAS Google Scholar
Meredith RF, Alvarez RD, Partridge EE, Khazaeli MB, Lin CY, Macey DJ, et al. Intraperitoneal radioimmunochemotherapy of ovarian cancer: a phase I study.Cancer Biother Radiopharm 2001; 16:305–315. ArticlePubMedCAS Google Scholar
Alvarez RD, Huh WK, Khazaeli MB, Meredith RF, Partridge EE, Kilgore LC, et al. A phase I study of combined modality (90)yttrium-CC49 intraperitoneal radioimmunotherapy for ovarian cancer.Clin Cancer Res 2002; 8:2806–2811. PubMedCAS Google Scholar
Colcher D, Bird R, Roselli M, Hardman KD, Johnson S, Pope S, et al.In vivo tumor targeting of a recombinant single-chain antigen-binding protein.J Natl Cancer Inst 1990; 82:1191–1197. ArticlePubMedCAS Google Scholar
Adams GP, McCartney JE, Tai MS, et al. Highly specific_in vivo_ tumor targeting by monovalent and divalent forms of 741F8 anti-c-erbB-2 single-chain Fv.Cancer Res 1993; 53:4026–4034. PubMedCAS Google Scholar
Yokota T, Milenic DE, Whitlow M, Wood JF, Hubert SL, Schlom J. Micro autoradiographic analysis of the normal organ distribution of radioiodinated single-chain Fv and other immunoglobulin forms.Cancer Res 1993; 53:3776–3783. PubMedCAS Google Scholar
Larson SM, El-Shirbiny AM, Divgi CR, Sgouros G, Finn RD, Tschmelitsch J, et al. Single chain antigen binding protein (scFv CC49): first human studies in colorectal carcinoma metastatic to liver.Cancer 1997; 80:2458–2468. ArticlePubMedCAS Google Scholar
Chang CH, Sharkey RM, Rossi EA, Karacay H, McBride W, Hansen HJ, et al. Molecular advances in pretargeting radioimmunotherapy with bispecific antibodies.Mol Cancer Ther 2002; 1:553–563. PubMedCAS Google Scholar
Sharkey RM, McBride WJ, Karacay H, Chang K, Griffiths GL, Hansen HJ, et al. A universal pretargeting system for cancer detection and therapy using bispecific antibody.Cancer Res 2003; 63:354–363. PubMedCAS Google Scholar
Hnatowich DJ, Virzi F, Rusckowski M. Investigations of avidin and biotin for imaging applications.J Nucl Med 1987; 28:1294–1302. PubMedCAS Google Scholar
Axworthy DB, Reno JM, Hylarides MD, Mallett RW, Theodore LJ, Gustavson LM, et al. Cure of human carcinoma xenografts by a single dose of pretargeted yttrium-90 with negligible toxicity.Proc Natl Acad Sci USA 2000; 97:1802–1807. ArticlePubMedCAS Google Scholar
Breitz HB, Weiden PL, Beaumier PL, Axworthy DB, Seiler C, Su FM, et al. Clinical optimization of pretargeted radioimmunotherapy with antibody-streptavidin conjugate and90Y-DOTA-biotin.J Nucl Med 2000; 41:131–140. PubMedCAS Google Scholar
Paganelli G, Riva P, Deleide G, Clivio A, Chiolerio F, Scassellati GA, et al.In vivo labeling of biotinylated monoclonal antibodies by radioactive avidin: a strategy to increase tumor radiolocalization.Int J Cancer 1988; 2(Suppl):121–125. ArticleCAS Google Scholar
Wiseman GA, White CA, Stabin M, Dunn WL, Erwin W, Dahlbom M, et al. Phase I/II90Y-Zevalin (yttrium-90 ibritumomab tiuxetan, IDEC-Y2B8) radioimmunotherapy dosimetry results in relapsed or refractory non-Hodgkin’s lymphoma.Eur J Nucl Med Mol Imag 2000; 27:766–777. ArticleCAS Google Scholar
Davis TA, Kaminski MS, Leonard JP, Hsu FJ, Wilkinson M, Zelenetz A, et al. The Radioisotope Contributes Significantly to the Activity of Radioimmunotherapy.Clin Cancer Res 2004; 10:7792–7798. ArticlePubMedCAS Google Scholar
DeNardo GL, DeNardo SJ, Lamborn KR, Goldstein DS, Levy NB, Lewis JP, et al. Low-dose, fractionated radioimmunotherapy for B-cell malignancies using131I-Lym-l antibody.Cancer Biother Radiopharm 1998; 13:239–254. ArticlePubMedCAS Google Scholar
O’Donnell RT, Shen S, Denardo SJ, Wun T, Kukis DL, Goldstein DS, Denardo GL. A phase I study of90Y-2IT-BAD-Lym-1 in patients with non-Hodgkin’s lymphoma.Anticancer Res 2000; 20:3647–3655. PubMedCAS Google Scholar
Stashenko P, Nadler LM, Hardy R, Schlossman SF. Characterization of a human B lymphocyte-specific antigen.J Immunol 1980; 125:1678–1685. PubMedCAS Google Scholar
Witzig TE, White CA, Wiseman GA, Gordon LI, Emmanouilides C, Raubitschek A, et al. Phase I/II Trial of IDEC-Y2B8 Radioimmunotherapy for Treatment of Relapsed or Refractory CD20+ B-Cell Non-Hodgkin’s Lymphoma.J Clin Oncol 1999; 17:3793–3803. PubMedCAS Google Scholar
Witzig TE, Gordon LI, Cabanillas F, Czuczman MS, Emmanouilides C, Joyce R, et al. Randomized Controlled Trial of Yttrium-90-Labeled Ibritumomab Tiuxetan Radioimmunotherapy versus Rituximab Immunotherapy for Patients with Relapsed or Refractory Low-Grade, Follicular, or Transformed B-Cell Non-Hodgkin’s Lymphoma.J Clin Oncol 2002; 20:2453–2463. ArticlePubMedCAS Google Scholar
Wiseman GA, Gordon LI, Multani PS, Witzig TE, Spies S, Bartlett NL, et al. Ibritumomab tiuxetan radioimmunotherapy for patients with relapsed or refractory non-Hodgkin lymphoma and mild thrombocytopenia: a phase II multicenter trial.Blood 2002; 99:4336–4342. ArticlePubMedCAS Google Scholar
Witzig TE, Flinn IW, Gordon LI, Emmanouilides C, Czuczman MS, Saleh MN, et al. Treatment with ibritumomab tiuxetan radioimmunotherapy in patients with rituximabrefractory follicular non-Hodgkin’s lymphoma.J Clin Oncol 2002; 20:3262–3269. ArticlePubMedCAS Google Scholar
Gordon LI, Molina A, Witzig TE, Emmanouilides C, Raubtischek A, Darif M, et al. Durable responses after ibritumomab tiuxetan radioimmunotherapy for CD20+ B-cell lymphoma: long-term follow-up of a phase 1/2 study.Blood 2004; 103:4429–4431. ArticlePubMedCAS Google Scholar
Kaminski MS, Zasadny KR, Francis IR, Fenner MC, Ross CW, Milik AW, et al. Iodine-131 -anti-B 1 radioimmunotherapy for B-cell lymphoma.J Clin Oncol 1996; 14:1974–1981. PubMedCAS Google Scholar
Kaminski MS, Estes J, Zasadny KR, Francis IR, Ross CW, Tuck M, et al. Radioimmunotherapy with iodine (131)I tositumomab for relapsed or refractory B-cell non-Hodgkin lymphoma: updated results and long-term follow-up of the University of Michigan experience.Blood 2000; 96:1259–1266. PubMedCAS Google Scholar
Kaminski MS, Zelenetz AD, Press OW, Saleh M, Leonard J, Fehrenbacher L, et al. Pivotal Study of Iodine I 131 Tositumomab for Chemotherapy-Refractory Low-Grade or Transformed Low-Grade B-Cell Non-Hodgkin’s Lymphomas.J Clin Oncol 2001; 19:3918–3928. PubMedCAS Google Scholar
Dillman RO. Radiolabeled Anti-CD20 Monoclonal Antibodies for the Treatment of B-Cell Lymphoma.J Clin Oncol 2002; 20:3545–3557. ArticlePubMedCAS Google Scholar
Wahl RL, Kroll S, Zasadny KR. Patient-specific whole-body dosimetry: principles and a simplified method for clinical implementation.J Nucl Med 1998; 39:14S-20S. PubMedCAS Google Scholar
Rutar FJ, Augustine SC, Colcher D, Siegel JA, Jacobson DA, Tempero MA, et al. Outpatient Treatment with131I-Anti-Bl Antibody: Radiation Exposure to Family Members.J Nucl Med 2001 ; 42:907–915. PubMedCAS Google Scholar
Harwood SJ, Gibbons LK, Goldner PJ, Webster WB, Carroll RG. Outpatient radioimmunotherapy with Bexxar: Closed, clean air reservoir minimizes personnel radiation exposure.Cancer 2002; 94:1358–1362. ArticlePubMedCAS Google Scholar
Davis TA, Kaminski MS, Leonard JP, Hsu FJ, Wilkinson M, Zelenetz A, et al. The Radioisotope Contributes Significantly to the Activity of Radioimmunotherapy.Clin Cancer Res 2004; 10:7792–7798. ArticlePubMedCAS Google Scholar
Kaminski MS, Tuck M, Estes J, Kolstad A, Ross CW, Zasadny K, et al.131I-Tositumomab Therapy as Initial Treatment for Follicular Lymphoma.N Engl J Med 2005; 352:441–149. ArticlePubMedCAS Google Scholar
Weiden PL, Breitz HB, Press O, Appelbaum JW, Bryan JK, Gaffigan S, et al. Pretargeted radioimmunotherapy (PRIT) for treatment of non-Hodgkin’s lymphoma (NHL): initial phase I/II study results.Cancer Biother Radiopharm 2000; 15:15–29. ArticlePubMedCAS Google Scholar
Forero A, Weiden PL, Vose JM, Knox SJ, LoBuglio AF, Hankins J, et al. Phase 1 trial of a novel anti-CD20 fusion protein in pretargeted radioimmunotherapy for B-cell non-Hodgkin lymphoma.Blood 2004; 104:227–236. ArticlePubMedCAS Google Scholar
Huhn D, von Schilling C, Wilhelm M, Ho AD, Hallek M, Kuse R, et al. German Chronic Lymphocytic Leukemia Study Group. Rituximab therapy of patients with B-cell chronic lymphocytic leukemia.Blood 2001; 98:1326–1331. ArticlePubMedCAS Google Scholar
Lin TS, Lucas MS, Byrd JC. Rituximab in B-cell chronic lymphocytic leukemia.Semin Oncol 2003; 30:483–492. ArticlePubMedCAS Google Scholar
Lin TS, Flinn IW, Lucas MS, Porcu P, Sickler J, Moran ME, et al. Filgrastim and alemtuzumab (Campath-1H) for refractory chronic lymphocytic leukemia.Leukemia 2005 (in press).
Linenberger ML. CD33-directed therapy with gemtuzumab ozogamicin in acute myeloid leukemia: progress in understanding cytotoxicity and potential mechanisms of drug resistance.Leukemia 2005; 19:176–182. ArticlePubMedCAS Google Scholar
DiJoseph JF, Goad ME, Dougher MM, Boghaert ER, Kunz A, Hamann PR, et al. Potent and specific antitumor efficacy of CMC-544, a CD22-targeted immunoconjugate of calicheamicin, against systemically disseminated B-cell lymphoma.Clin Cancer Res 2004; 10:8620–8629. ArticlePubMedCAS Google Scholar