Enterocyte chloride and water secretion into the small intestine after enterotoxin challenge: Unifying hypothesis or intellectual dead end? (original) (raw)

References

  1. Al-Balool, F.Y. Effects of tetrodotoxin and ion replacement on the short circuit current induced by_Escherichia coli_ heat stable enterotoxin across small intestine of the gerbil (Gerbillus cheesmani). Mem Inst Oswaldo Cruz, 99 (2), 141–145.
    Google Scholar
  2. Asakura, H., Tsuchiya, M., Watanabe, Y., Enomoto, Y., Morita, A., Morishita, T., Fukumi, H., Ohashi, M., Castro, A. and Uylangco, C. (1974). Electron microscopic study on the jejunal mucosa in cholera. Gut, 15, 531–544.
    Article CAS PubMed Google Scholar
  3. Carpenter, C.C.J., Greenough III, W.B. and Sack, R.B. (1969). The relationship of superior mesenteric blood flow to gut electrolyte loss in experimental cholera. J infectious Dis, 120, 182–193.
    Google Scholar
  4. Chao, A.C., de Sauvage, F.J., Dong, Y.J., Wagner, J.A. Goeddel, D.V. and Gardner, P. (1994). Activation of intestinal CFTR Cl− channel by heat stable enterotoxin and guanylin via cAMP dependent protein. EMBO Journal, 13, 1065–1072.
    CAS PubMed Google Scholar
  5. Cuthbert, A.W., Hickman, M.E., MacVinish, L.J., Evans, M.J., Colledge, W.H., Ratcliffe, R., Seale, P.W. and Humphrey, P.P.A. (1994). Chloride secretion in response to guanylin in colonic epithelia from normal and transgenic cystic fibrosis mice. Brit J Pharmacol, 112, 31–36.
    CAS Google Scholar
  6. Eklund, S., Jodal, M. and Lundgren, O. (1985). The enteric nervous system participates in the secretory response to the heat stable enterotoxins of_Escherichia coli_ in rats and cats. Neuroscience, 14, 673–681.
    Article CAS PubMed Google Scholar
  7. Fasano, A., Uzzau, S., Fiore, C. and Margaretten, K. (1997). The enterotoxic effect of zona occludens toxin on rabbit small intestine involves the paracellular pathway. Gastroenterology, 112, 839–846.
    Article CAS PubMed Google Scholar
  8. Field, M. (1971). Intestinal secretion: effect of cyclic AMP and its role in cholera. New Engl J Med, 284, 1137–1143.
    Article CAS Google Scholar
  9. Field, M. (2003). Intestinal ion transport and the pathophysiology of diarrhea. J. Clin Invest, 111, 931–943.
    CAS PubMed Google Scholar
  10. Field, M. et al., (1978). Heat-stable enterotoxin of_Escherichia coli: In vitro_ effects on guanylate cyclase activity, cyclic GMP concentration, and ion transport in small intestine. Proc. Nat Acad Sci USA, 75, 2800–2804.
    Article CAS PubMed Google Scholar
  11. Forte, L.R., Eber, S.L., Turner, J.T., Freeman, R.H., Fok, K.F. and Currie, M.G. (1993). Guanylin stimulation of Cl− secretion in human intestinal T84 cells via cyclic guanosine monophosphate. J Clin Invest, 91, 2423–2428.
    Article CAS PubMed Google Scholar
  12. Flagella, M., Clarke, L.L., Miller, M.L., Erway, L.C., Gianella, R.A., Andringa, A., Gawenis, L.R., Kramer, J., Duffy, J.J., Doetschman, T., Lorenz, J.N., Yamoah, E.N., Cardell, E.L. and Shull, G.E. (1999). Mice lacking the basolateral Na-K-2Cl contransporter have impaired epithelial chloride secretion and are profoundly deaf. J Biol Chem, 274, 26949–26955.
    Article Google Scholar
  13. Gianella, R.A. (1976). Suckling mouse model for detection of heat-stable_Escherichia coli_ enterotoxin: characteristics of the model. Infect Immun, 14, 95–99.
    Google Scholar
  14. Goldstein, J.L., Sahi, J., Bhuva, M., Layden, T.J. and Rao, M.C. (1994). Escherichia coli heat-stable enterotoxin-mediated colonic Cl− secretion is absent in cystic fibrosis. Gastroenterology, 107, 950–956.
    CAS PubMed Google Scholar
  15. Gordon, R. S. Jr., Gardener, J.D. and Kinzie, J.L. (1972). Low mannitol clearance unto cholera stool against filtration as the source of stool fluid. Gastroenterology, 63, 407–412.
    PubMed Google Scholar
  16. Gregory, R.A. (1962). Secretory mechanisms of the gastrointestinal tract, Physiological Society Monograph. Cambridge University Press.
    Google Scholar
  17. Guandalini, S., Rao, M. R., Smith, P.L. and Field, M. (1982). cGMP modulation of ileal ion transport: in vitro effects of_Escherichia coli_ heat-stable enterotoxin. Am J Physiol, 243, G36-G41.
    CAS PubMed Google Scholar
  18. Hamilton, D.L., Roe, W.E. and Nielsen, N.O. (1976). Effects of heat-stable and heat labile_Escherichia coli_ enterotoxins, cholera toxin and theophylline on unidirectional sodium and chloride fluxes in the proximal and distal jejunum of weanling swine. Can J Com med, 41, 306–317.
    Google Scholar
  19. Harris, M.S., Ramaswamy, K. and Kennedy, J.G. (1989) Induction of neurally mediated NaHCO3 secretion by luminal distension in rat ileum. Am J Physiol, 257, G191-G197.
    CAS PubMed Google Scholar
  20. Hendrix, T.R. (1975): In “_Intestinal Absorption and Malabsorptio_”, Csaky, T.Z. (Ed.), Raven Press, New York, pp. 253–271.
    Google Scholar
  21. Hendrix, T.R. and Bayless, T.M. (1970). Intestinal secretion. Ann Rev Physiol, 32, 139–164
    Article CAS Google Scholar
  22. Huott, P.A., Liu, W., McRoberts, J.A., Giannella, R.A. and Dharmsathaphorn, K. (1988). Mechanism of action of_Escherichia coli_ heat stable enterotoxin in a human colonic cell line. J Clin Invest, 82, 514–523.
    Article CAS PubMed Google Scholar
  23. Jiang, M. M., Kirchgessner, A., Gershon, M.D. and Suprenant, A. (1993). Cholera-toxin-sensitive neurons in guinea pig submucosal plexus. Am J Physiol, 264, G86-G94.
    CAS PubMed Google Scholar
  24. Jodal, M., Lundgren, O. and Naftalin, R.J. (1987). Changes_in vivo_ in rat ileal fluid uptake and mucosal volume induced by changes in the tonicity of the luminal perfusion fluid. J. Physiol, 391, 29P.
    Google Scholar
  25. Koryta, J., Dvorak, J. and Bohackova, V. (1973): In “_Electrochemistry_”, Methuen & Co, London. p. 246.
    Google Scholar
  26. Kuhn, M., Adermann, K., Jaehne, J., Forssmann W.G. and Rechkemmer, G. (1994). Segmental differences in the effects of guanylin and_Escherichia coli_ heat-stable enterotoxin on Cl− secretion in human gut, J Physiol, 479, 433–440.
    CAS PubMed Google Scholar
  27. Love, A.H.G. (1969a) Permeability characteristics of the cholera infected small intestine. Gut, 10, 105–107.
    Article CAS PubMed Google Scholar
  28. Love, A.H.G. (1969b). Water and sodium absorption by the intestine in cholera. Gut, 10, 63–67.
    Article CAS PubMed Google Scholar
  29. Lucas, M.L. (2005). Amendments to the theory underlying Ussing chamber data of chloride ion secretion after bacterial enterotoxin exposure. J Theor Biol, 234, 21–37.
    Article CAS PubMed Google Scholar
  30. Lucas, M.L., Thom, M.M.M., Bradley, J.M., O’Reilly, N.F., McIlvenny, T.J. and Nelson, Y.B. (2005). Escherichia coli heat stable (STa) enterotoxin and the upper small intestine: lack of evidence_in vivo_ for net fluid secretion. J. Membrane Biol, 206, 29–42.
    Article CAS Google Scholar
  31. Lucas, M.L., Duncan, N.W., O’Reilly, N.F., McIlvenny, T.J. and Nelson, Y.B. (2008): Lack of remote vagally-mediated restoration of_Escherichia coli_ enterotoxin (STa) inhibited fluid absorption from rat proximal jejunum. Neurogastroent Motil (in press).
  32. Mathan, M.M., Chandy, G. and Mathan, V.I. (1995). Ultrastructural changes in the upper small intestinal mucosa in patients with cholera. Gastroenterology, 109, 422–430.
    Article CAS PubMed Google Scholar
  33. Miller, D.L. and Schedl, H.P. (1970). Total recovery studies of nonabsorbable indicators in the rat small intestine. Gastroenterology, 58, 40–46.
    CAS PubMed Google Scholar
  34. Moreau, A. (1868). Über die Folgen der Durchschneidung der Darmnerven. Centralblatt für med Wissenschaft, 14, 209–211.
    Google Scholar
  35. Nelson, Y.B., Pande, D., McCormick, J, Balloch, K.J.D. and Lucas, M.L. (2007). Lack of evidence_in vivo_ for nitrergic inhibition by_Escherichia coli_ (STa) enterotoxin of fluid absorption from rat proximal jejunum. J Physiol Biochem, 63 (3), 1–7.
    Article Google Scholar
  36. Nobles, M., Diener, M. and Rummel, W. (1991). Segment specific effects of the heat-stable enterotoxin of_E. coli_ on electrolyte transport in the rat colon. Eur J Pharmacology, 202, 201–211.
    Article CAS Google Scholar
  37. Owles, W.H. (1937). Investigations of the functions of the small intestine in man by Intestinal intubation. III Factors affecting the secretion of juice by the small intestine. Clin Sci, 3, 21–35.
    CAS Google Scholar
  38. Pappenheimer, J.R. and Reiss, K.Z. (1987). Contribution of solvent drag through intracellular junctions to absorption of nutrients by the small intestine of the rat. J Membrane Biol, 100, 123–136.
    Article CAS Google Scholar
  39. Pollitzer, R. (1959). Cholera. Monograph, 43, Geneva, World Health Authority.
    Google Scholar
  40. Powell, D. W., Binder, H. J. and Curran, P.F. (1973). Active electrolyte secretion stimulated by choleragen in rabbit ileum_in vitro_. Am J Physiol, 225, 781–787.
    CAS PubMed Google Scholar
  41. Robert, A., Nezamis, J.E., Lancaster, C., Hanchar, A.J. and Klepper, M.S. (1976). Enteropooling assay — test for diarrhea produced by prostaglandins. Prostaglandins, 11, 809–828.
    Article CAS PubMed Google Scholar
  42. Rolfe, V. and Levin, R.J. (1994). Enterotoxin_Escherichia coli_ STa activates a nitric oxidedependent myenteric plexus secretory reflex in the rat ileum. J Physiol, 475, 531–537.
    CAS PubMed Google Scholar
  43. Rolfe, V.E. and Levin, R.J. (1999). Vagotomy inhibits the jejunal fluid secretion activated by luminal ileal_Escherichia coli_ STa in the rat_in vivo_. Gut, 44, 615–619.
    Article CAS PubMed Google Scholar
  44. Ross, G. (1978): Essentials of Human Physiology, Year Book Medical Publishers, Chicago, USA.
    Google Scholar
  45. Russo, M.A., Högenauer, C., Coates Jr., S.W. Santa Ana, C.A., Porter, J.L., Rosenblatt, R.L. Emmett, M. and Fordtran, J.S. (2003). Abnormal passive chloride absorption in cystic fibrosis jejunum functionally opposes the classic chloride secretory defect. J Clin Invest, 112, 118–125.
    CAS PubMed Google Scholar
  46. Savitch, V.V. and Sochestvensky, N.A. (1917). L’influence du nerf vague sur la secretion de l’intestine. Compt Rendus Seanc Soc Biol, 80, 508–509.
    Google Scholar
  47. Schirgi-Degen, A. and Beubler, E. (1998). Proabsorptive properties of nitric oxide. Digestion, 59, 400–403
    Article CAS PubMed Google Scholar
  48. Sjövall, H., Brunnson, I., Jodal, M. and Lundgren, O. (1983). The effect of vagal nerve-stimulation on net fluid transport in the small-intestine of the cat. Acta Physiol Scand, 117, 351–357.
    Article PubMed Google Scholar
  49. Sladen, G.E. and Harries, J.T. (1972). Studies on the effects of unconjugated dihydroxy bile salts on rat small intestinal function_in vivo_. Biochim Biophys Acta, 288, 443–456.
    Article CAS PubMed Google Scholar
  50. Solomon, A.K. (1964): In “_Transcellular membrane potentials and ionic fluxes_”, F. M. Snell and W.K. Noell (Eds.), Gordon & Breach, New York & London.
    Google Scholar
  51. Starling, E.H. (1911): Recent Advances in the Physiology of Digestion (2nd Ed.), Lecture 9, Constable, London.
    Google Scholar
  52. Störk, O. (1916). Über cholera. Beitraege zur Pathologische Anatomie, 62, 9–174
    Google Scholar
  53. Thiry, L. (1864) Über eine neue Methode, den Dünndarm zu isolieren. Sitzungsb d.K. Akademie d.Wissenschaft, 50, 77–96.
    Google Scholar
  54. Turvill, J.L., Kasapidis, P. and Farthing, M.J.G. (1999). The sigma ligand, igmesine, inhibits cholera toxin and Escherichia coli enterotoxin induced jejunal secretion in the rat. Gut, 45, 564–569.
    Article CAS PubMed Google Scholar
  55. Vaandrager, A.B., Bot, A.G.M and De Jonge, H.R. (1997). Guanosine 3′, 5′-cyclic monophosphate-dependent protein kinase II mediates heatstable enterotoxin-provoked chloride secretion in rat intestine. Gastroenterology, 112, 437–443.
    Article CAS PubMed Google Scholar
  56. Wendt, E. (1885): In “_A treatise on Asiatic cholera_”, William Wood & Co., New York, USA, pp. 226.
    Google Scholar
  57. Wilson, T.H. (1962). “_Intestinal absorption_”, W. B. Saunders Press, Philadephia & London.
    Google Scholar
  58. Winne, D. and Goerig, H. (1982). Appearance of14C-polyethylene glycol 4000 in intestinal venous blood: influence of osmolarity and laxatives, effect on net water flux determination. Naunyn-Schmiedeberg’s Archiv. fuer. Pharmakologie, 321, 149–156.
    Article CAS Google Scholar
  59. Yablonski, M.E. and Lifson, N. (1976). Mechanism of production of intestinal secretion by elevated venous pressure. J Clin Invest, 57, 904–915.
    Article CAS PubMed Google Scholar
  60. Yardley, J.H. and Brown, G.D. (1973). Horseradish peroxidase studies in the intestine in experimental cholera. Lab Invest, 28, 482–493.
    CAS PubMed Google Scholar
  61. Young, A. and Levin, R.J. (1992). Intestinal hypersecretion of the refed starved rat: a model for alimentary diarrhoea. Gut, 33, 1050–1056.
    Article CAS PubMed Google Scholar
  62. Young, A., Pereira, M.M.C., Warren, M.A. and Levin, R.J. (1988). Hypersecretion associated with the action of_Escherichia coli_ STa enterotoxin on jejunum and ileum from starved and chronically undernourished rats. Med Sci Res, 16, 573–574.
    CAS Google Scholar
  63. Yule, H. and Burnell, A.C. (1903). A glossary of colloquial Anglo-Indian words and phrases and of kindred terms, etymological, historical, geographical and discursive. John Murray, London. pp. 589–589.
    Google Scholar

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