The ontogenetic development of the follicular dendritic cell (original) (raw)
Summary
After intravenous injection of horseradish peroxidase (HRP)-anti-HRP complexes in 21-day-old rats, complex trapping occurs on reticulum cells, forming the stroma of primary follicles of spleens. After intravenous injection of the same complexes in young adult rats (48 days old), trapping occurs on characteristic follicular dendritic cells (FDCs) located in well-developed germinal centers. These results strongly suggest that the follicular dendritic cell originates from a reticulum cell.
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Abbreviations
FDC :
follicular dendritic cell
FRC :
fibroblastic reticulum cells
HRP :
horseradish peroxidase
RC :
reticulum cell
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Authors and Affiliations
- Department of Histology, Free University, Amsterdam, The Netherlands
E. W. A. Kamperdijk - Department of Electronmicroscopy, Medical Faculty, Free University, Amsterdam, The Netherlands
Christine D. Dijkstra & E. A. Döpp
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- Christine D. Dijkstra
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Dijkstra, C.D., Kamperdijk, E.W.A. & Döpp, E.A. The ontogenetic development of the follicular dendritic cell.Cell Tissue Res. 236, 203–206 (1984). https://doi.org/10.1007/BF00216532
- Accepted: 08 December 1983
- Issue Date: April 1984
- DOI: https://doi.org/10.1007/BF00216532