Use of an intravascular endoprosthesis (stent) to establish and maintain short-term patency of the ductus arteriosus in newborn lambs (original) (raw)

Abstract

The feasibility of stenting the ductus arteriosus with a balloon-expandable vascular endoprosthesis was tested in 8 newborn lambs. Tantalum wire and stainless steel mesh coronary stents were implanted antegrade or retrograde by percutaneous transfemoral catheterization. One lamb died during the procedure from perforation of the aorta. In 7 lambs, the ductus arteriosus was crossed using endhole catheters and wires, and stents mounted on angioplasty catheters were expanded in the ductus arterisus. Six lambs had successful implantation and had maintained a sizeable patent ductus arteriosus at 2 h. We conclude that the feasibility of percutaneous stenting of the newborn ductus was demonstrated. By providing patency of the ductus arteriosus, stents may offer nonsurgical alternatives for palliation of cyanotic congenital heart disease and hypoplastic left heart syndrome

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Authors and Affiliations

  1. Section of Pediatric Cardiology, Walter Reed Army Medical Center, Washington, D.C., USA
    John W. Moore, William C. Kirby, Ethridge J. Lovett & J. Timothy O'Neill
  2. Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA
    John W. Moore, William C. Kirby, Ethridge J. Lovett & J. Timothy O'Neill

Authors

  1. John W. Moore
  2. William C. Kirby
  3. Ethridge J. Lovett
  4. J. Timothy O'Neill

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The opinions expressed are those of the authors and are not to be construed as official or as reflecting the views of the Army or the Department of Defense.

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Moore, J.W., Kirby, W.C., Lovett, E.J. et al. Use of an intravascular endoprosthesis (stent) to establish and maintain short-term patency of the ductus arteriosus in newborn lambs.Cardiovasc Intervent Radiol 14, 299–301 (1991). https://doi.org/10.1007/BF02578454

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