Telomere length and telomerase activity during expansion and differentiation of human mesenchymal stem cells and chondrocytes (original) (raw)
Harley CB, Futcher AB, Greider CW (1990) Telomeres shorten during aging of human fibroblasts. Nature 345 458–460 Google Scholar
Harley CB, Vaziri H, Counter CM, Allsopp RC (1992) The telomere hypothesis of cellular aging. Exp Gerontol 27:375–382 CASPubMed Google Scholar
Hayflick L (1965) The limited in vitro lifetime of human diploid cell strains. Exp Cell Res 37:614–636 CASPubMed Google Scholar
Allsopp RC, Vaziri H, Patterson C, Goldstein S, Younglai EV, Futcher AB et al (1992) Telomere length predicts replicative capacity of human fibroblasts. Proc Natl Acad Sci USA 89:10114–10118 CASPubMed Google Scholar
Blasco MA, Lee HW, Hande MP, Samper E, Lansdorp PM, DePinho RA et al (1997) Telomere shortening and tumor formation by mouse cells lacking telomerase RNA. Cell 91:25–34 ArticleCASPubMed Google Scholar
Hackett JA, Feldser DM, Greider CW (2001) Telomere dysfunction increases mutation rate and genomic instability. Cell 106:275–286 CASPubMed Google Scholar
Counter CM, Avilion AA, LeFeuvre CE, Stewart NG, Greider CW, Harley CB et al (1992) Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J 11:1921–1929 CASPubMed Google Scholar
Greider CW (1998) Telomerase activity, cell proliferation, and cancer. Proc Natl Acad Sci USA 95:90–92 ArticleCASPubMed Google Scholar
Aue G, Muralidhar B, Schwartz HS, Butler MG (1998) Telomerase activity in skeletal sarcomas. Ann Surg Oncol 5:627–634 CASPubMed Google Scholar
Shay JW, Bacchetti S (1997) A survey of telomerase activity in human cancer. Eur J Cancer 33:787–791 ArticleCASPubMed Google Scholar
Caporaso GL, Chao MV (2001) Telomerase and oligodendrocyte differentiation. J Neurobiol 49:224–234 ArticleCASPubMed Google Scholar
Weng NP, Levine BL, June CH, Hodes RJ (1996) Regulated expression of telomerase activity in human T lymphocyte development and activation. J Exp Med 183:2471–2479 CASPubMed Google Scholar
Parsch D, Brummendorf TH, Richter W, Fellenberg J (2002) Replicative aging of human articular chondrocytes during ex vivo expansion. Arthritis Rheum 46:2911–2916 ArticleCASPubMed Google Scholar
Yui J, Chiu CP, Lansdorp PM (1998) Telomerase activity in candidate stem cells from fetal liver and adult bone marrow. Blood 91:3255–3262 CASPubMed Google Scholar
Engelhardt M, Kumar R, Albanell J, Pettengell R, Han W, Moore MA (1997) Telomerase regulation, cell cycle, and telomere stability in primitive hematopoietic cells. Blood 90:182–193 CASPubMed Google Scholar
Martin JA, Ellerbroek SM, Buckwalter JA (1997) Age-related decline in chondrocyte response to insulin-like growth factor-I: the role of growth factor binding proteins. J Orthop Res 15:491–498 CASPubMed Google Scholar
Brittberg M, Lindahl A, Nilsson A, Ohlsson C, Isaksson O, Peterson L (1994) Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation. N Engl J Med 331:889–895 CASPubMed Google Scholar
Brittberg M, Nilsson A, Lindahl A, Ohlsson C, Peterson L (1996) Rabbit articular cartilage defects treated with autologous cultured chondrocytes. Clin Orthop 326:270–283 PubMed Google Scholar
Peterson L, Brittberg M, Kiviranta I, Akerlund EL, Lindahl A (2002) Autologous chondrocyte transplantation. Biomechanics and long-term durability. Am J Sports Med 30:2–12 PubMed Google Scholar
Reyes M, Lund T, Lenvik T, Aguiar D, Koodie L, Verfaillie CM (2001) Purification and ex vivo expansion of postnatal human marrow mesodermal progenitor cells. Blood 98:2615–2625 CASPubMed Google Scholar
Banfi A, Bianchi G, Notaro R, Luzzatto L, Cancedda R, Quarto R (2002) Replicative aging and gene expression in long-term cultures of human bone marrow stromal cells. Tissue Eng 8:901–910 ArticleCASPubMed Google Scholar
Berry L, Grant ME, McClure J, Rooney P (1992) Bone-marrow-derived chondrogenesis in vitro. J Cell Sci 101:333–342 PubMed Google Scholar
Reyes M, Verfaillie CM (2001) Characterization of multipotent adult progenitor cells, a subpopulation of mesenchymal stem cells. Ann NY Acad Sci 938:231–233 CASPubMed Google Scholar
Winter A, Breit S, Parsch D, Benz K, Steck E, Hauner H et al (2003) Cartilage-like gene expression in differentiated human stem cell spheroids: a comparison of bone marrow-derived and adipose tissue-derived stromal cells. Arthritis Rheum 48:418–429 ArticleCASPubMed Google Scholar
Martin JA, Buckwalter JA (2001) Telomere erosion and senescence in human articular cartilage chondrocytes. J Gerontol A Biol Sci Med Sci 56:B172–B179 Google Scholar
Martin JA, Buckwalter JA (2003) The role of chondrocyte senescence in the pathogenesis of osteoarthritis and in limiting cartilage repair. J Bone Joint Surg Am 85 [Suppl 2]:106–110
Cawthon RM, Smith KR, O’Brien E, Sivatchenko A, Kerber RA (2003) Association between telomere length in blood and mortality in people aged 60 years or older. Lancet 361 393–395 Google Scholar
Brummendorf TH, Maciejewski JP, Mak J, Young NS, Lansdorp PM (2001) Telomere length in leukocyte subpopulations of patients with aplastic anemia. Blood 97:895–900 ArticleCASPubMed Google Scholar
Vulliamy T, Marrone A, Goldman F, Dearlove A, Bessler M, Mason PJ et al (2001) The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita. Nature 413 432–435 Google Scholar
Vaziri H, Schachter F, Uchida I, Wei L, Zhu X, Effros R et al (1993) Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes. Am J Hum Genet 52:661–667 Google Scholar
Smilenov LB, Dhar S, Pandita TK (1999) Altered telomere nuclear matrix interactions and nucleosomal periodicity in ataxia telangiectasia cells before and after ionizing radiation treatment. Mol Cell Biol 19:6963–6971 CASPubMed Google Scholar
Rufer N, Brummendorf TH, Kolvraa S, Bischoff C, Christensen K, Wadsworth L et al (1999) Telomere fluorescence measurements in granulocytes and T lymphocyte subsets point to a high turnover of hematopoietic stem cells and memory T cells in early childhood. J Exp Med 190:157–167 ArticleCASPubMed Google Scholar
Chang E, Harley CB (1995) Telomere length and replicative aging in human vascular tissues. Proc Natl Acad Sci USA 92:11190–11194 CASPubMed Google Scholar
Suda T, Suda J, Ogawa M (1984) Disparate differentiation in mouse hemopoietic colonies derived from paired progenitors. Proc Natl Acad Sci USA 81:2520–2524 CASPubMed Google Scholar
Mayani H, Dragowska W, Lansdorp PM (1993) Lineage commitment in human hemopoiesis involves asymmetric cell division of multipotent progenitors and does not appear to be influenced by cytokines. J Cell Physiol 157:579–586 CASPubMed Google Scholar
Brummendorf TH, Dragowska W, Zijlmans JMJM, Thornbury G, Lansdorp PM (1998) Asymmetric cell divisions sustain long-term hematopoiesis from single-sorted human fetal liver cells. J Exp Med 188:1117–1124 ArticleCASPubMed Google Scholar
Punzel M, Ho AD (2001) Divisional history and pluripotency of human hematopoietic stem cells. Ann NY Acad Sci 938:72–81 CASPubMed Google Scholar
Saretzki G, Von Zglinicki T (2002) Replicative aging, telomeres, and oxidative stress. Ann NY Acad Sci 959:24–29 CASPubMed Google Scholar
Tallheden T, Dennis JE, Lennon DP, Sjogren-Jansson E, Caplan AI, Lindahl A (2003) Phenotypic plasticity of human articular chondrocytes. J Bone Joint Surg Am 85 [Suppl 2]:93–100
Dell’Accio F, De Bari C, Luyten FP (2003) Microenvironment and phenotypic stability specify tissue formation by human articular cartilage-derived cells in vivo. Exp Cell Res 287:16–27 ArticleCASPubMed Google Scholar
Barbero A, Ploegert S, Heberer M, Martin I (2003) Plasticity of clonal populations of dedifferentiated adult human articular chondrocytes. Arthritis Rheum 48:1315–1325 ArticleCASPubMed Google Scholar
Rufer N, Dragowska W, Thornbury G, Roosnek E, Lansdorp PM (1998) Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry. Nat Biotechnol 16:743–747 CASPubMed Google Scholar
Baerlocher GM, Mak J, Tien T, Lansdorp PM (2002) Telomere length measurement by fluorescence in situ hybridization and flow cytometry: tips and pitfalls. Cytometry 47:89–99 ArticleCASPubMed Google Scholar
Piera-Velazquez S, Jimenez SA, Stokes D (2002) Increased life span of human osteoarthritic chondrocytes by exogenous expression of telomerase. Arthritis Rheum 46:683–693 ArticleCASPubMed Google Scholar
Zimmermann S, Voss M, Kaiser S, Kapp U, Waller CF, Martens UM (2003) Lack of telomerase activity in human mesenchymal stem cells. Leukemia 17:1146–1149 ArticleCASPubMed Google Scholar
Belair CD, Yeager TR, Lopez PM, Reznikoff CA (1997) Telomerase activity: a biomarker of cell proliferation, not malignant transformation. Proc Natl Acad Sci USA 94:13677–13682 ArticleCASPubMed Google Scholar
Harle-Bachor C, Boukamp P (1996) Telomerase activity in the regenerative basal layer of the epidermis inhuman skin and in immortal and carcinoma-derived skin keratinocytes. Proc Natl Acad Sci USA 93:6476–6481 CASPubMed Google Scholar
Slagboom PE, Droog S, Boomsma DI (1994) Genetic determination of telomere size in humans: a twin study of three age groups. Am J Hum Genet 55:876–882 Google Scholar
Tuli R, Li WJ, Tuan RS (2003) Current state of cartilage tissue engineering. Arthritis Res Ther 5:235–238 ArticleCASPubMed Google Scholar