Prediction of absolute risk of non-spinal fractures using clinical risk factors and heel quantitative ultrasound (original) (raw)

References

  1. Nguyen TV, Center JR, Sambrook PN, Eisman JA (2001) Risk factor for proximal humerus, forearm, and wrist fractures in elderly men and women. The Dubbo osteoporosis epidemiology study. Am J Epidemiol 153:587–595
    Article PubMed CAS Google Scholar
  2. Ismail AA, Pye SR, Cockerill WC, Lunt M, Silman AJ, Reeve J, Banzer D, Benevolenskaya LI, Bhalla A, Bruges J, Cannata JB, Cooper C, Delmas PD, Dequeker J, Dilsen G, Falch JA, Felsch B, Felsenberg D, Finn JD, Gennari C, Hoszowski K, Jajic I, Janott J, Johnell O, Kanis JA, Kragl A, Lopez A, Lorenc R, Lyritis G, Marchand F, Masaryk P, Matthis C, Miazgowski T, Naves-Diaz M, Pols HAP, Poor G, Rapado A, Raspe HH, Reid DM, Reisinger W, Scheidt-Nave C, Stepan J, Todd C, Weber K, Woolf AD, O’Neill TW (2002) Incidence of limb fracture across Europe: results from the European Prospective Osteoporosis Study (EPOS). Osteoporos Int 13:565–571
    Article PubMed CAS Google Scholar
  3. Johnell O, Kanis JA, Oden A, Sernbo I, Redlund-Johnell I, Petterson C, De Laet C, Jönsson B (2004) Mortality after osteoporotic fractures. Osteoporos Int 15:38–42
    Article PubMed CAS Google Scholar
  4. Seeley DJ, Browner WS, Genant HK, Nevitt MC, Scott JC, Cummings SR (1991) Which fractures are associated with low appendicular bone mass in elderly women? Ann Inter Med 115:837–842
    CAS Google Scholar
  5. Stone KL, Seeley DG, Lui LY, Cauley JA, Ensrud K, Browner WS, Nevitt MC, Cummings SR for the Study of Osteoporosis Fractures Research Group (2003) BMD at multiple sites and risk of fracture of multiple types: long-term results from the Study of Osteoporosis Fractures. J Bone Miner Res 18:1947–1954
    Article PubMed Google Scholar
  6. Kanis JA, Johnell O, Oden A, Dawson A, De Laet C, Jonsson B (2001) Ten year probabilities of osteoporosis fractures according to BMD and diagnostic threshold. Osteoporosis Int 12:989–995
    Article CAS Google Scholar
  7. Cummings SR, Nevitt MC, Browner WS, Stone K, Fox KM, Ensrud KE, Cauley J, Black D, Vogt TM; for The Study of Osteoporotic Fractures Research Group (1995) Risk factors for hip fracture in white women. N Engl J Med 332:767–773
    Article PubMed CAS Google Scholar
  8. Marshall D, Johnell O, Wedel H (1996) Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures. BMJ 312:1254–1259
    PubMed CAS Google Scholar
  9. Njeh CF, Fuerst T, Diessel E, Genant HK (2001) Is quantitative ultrasound dependent on bone structure?. A reflection. Osteoporos Int 12:1–15
    PubMed CAS Google Scholar
  10. Hernández JL, Marín F, González-Macías J, Diez-Perez A, Vila J, Gimenez S, Galán B, Arenas MS, Suárez F, Gayola L, Guillén G, Sagredo T, Belenguer R, Morón A, Arriaza E; for the ECOSAP study investigators (2004) Discriminative capacity of calcaneal quantitative ultrasound and fracture risk factors in postmenopausal women with osteoporotic fractures. Calcif Tissue Inter 74:357–365
    Article CAS Google Scholar
  11. Glüer CC, Eastell R, Reid DM, Felsenberg D, Roux C, Barkmann R, Timm W, Blenk T, Armbrecht G, Stewart A, Clowes J, Thomasius FE, Kolta S (2004) Association of five quantitative ultrasound devices and bone densitometry with osteoporotic vertebral fractures in a population-based sample: The OPUS Study. J Bone Miner Res 19:782–793
    Article PubMed Google Scholar
  12. Krieg MA, Cornuz J, Ruffieux C, Sandini L, Buche D, Dambacher MA, Hartl F, Häuselmann HJ, Kraenzlin M, Lippuner K, Neff M, Pancaldi P, Rizzioli R, Tanzi F, Theiler R, Tyndall A, Wimpfheimer K, Burckhardt P (2004) Comparison of three bone ultrasounds for the discrimination of subjects with and without osteoporotic fractures among 7562 elderly women. J Bone Miner Res 18:1261–1266
    Article Google Scholar
  13. Nguyen TV, Center JR, Eisman J (2004) Bone mineral density-independent association of quantitative ultrasound measurements and fracture risk in women. Osteoporos Int 15:942–947
    Article PubMed Google Scholar
  14. López-Rodríguez F, Mezquita-Raya P, de Dios Luna J, Escobar-Jiménez F, Muñoz-Torres M (2003) Performance of quantitative ultrasound in the discrimination of prevalent osteoporotic fractures in a bone metabolic unit. Bone 32:571–578
    Article PubMed Google Scholar
  15. Frost ML, Blake GM, Fogelman I (2002) A comparison of fracture discrimination using calcaneal quantitative ultrasound and dual X-ray absorptiometry in women with a history of fracture at sites other than the spine and hip. Calcif Tissue Int 71:207–211
    Article PubMed CAS Google Scholar
  16. Hartl F, Tyndall A, Kraenzlin M, Bachmeier C, Guckel C, Senn U, Hans D, Theiler R (2002) Discriminatory ability of quantitative ultrasound parameters and bone mineral density in a population-based sample of postmenopausal women with vertebral fractures: results of the Basel Osteoporosis Study. J Bone Miner Res 17:321–330
    Article PubMed CAS Google Scholar
  17. Karlsson MK, Duan Y, Ahlborg H, Obrant KJ, Johnell O, Seeman E (2001) Age, gender, and fragility fractures are associated with differences in quantitative ultrasound independent of bone mineral density. Bone 28:118–122
    Article PubMed CAS Google Scholar
  18. Marín F, González-Macías J, Díez-Pérez A, Palma S, Delgado-Rodríguez M (2006) Relationship between bone quantitative ultrasound and fractures: a meta-analysis. J Bone Miner Res 21:1126–1135
    Article PubMed Google Scholar
  19. Glüer CC; for the International Quantitative Ultrasound Consensus Group (1997) Quantitative ultrasound techniques for the assessment of osteoporosis: expert agreement on current status. J Bone Miner Res 12:1280–1288
    Article PubMed Google Scholar
  20. Díez-Pérez A, Marín F, Vila J, Abizanda M, Cervera A, Carbonell C, Alcolea RM, Cama A, Rama T, Galindo E, Olmos C (2003) Evaluation of calcaneal quantitative ultrasound in a primary care setting as a screening tool for osteopororosis in postmenopausal women. J Clin Densitom 6:237–246
    Article PubMed Google Scholar
  21. von Stetten E, Ouellet H, Wilson KE, Stein JA (1998) European caucasian female reference data values for the Sahara clinical bone sonometer. Bone 23(Suppl 5):S637. Abstract]
    Google Scholar
  22. Marín F, Vila J, González-Macías J; on behalf the ECOSAP project investigators (2003) Quantitative bone ultrasound: impact of the application of two different reference databases to a population of 5195 postmenopausal women. Med Clin (Barc) 121:250–252
    Article Google Scholar
  23. Eisen EA, Agalliu I, Thurston SW, Coull BA, Checkoway H (2004) Smoothing in occupational cohort studies: an illustration based on penalised splines. Occup Environ Med 61:854–860
    Article PubMed CAS Google Scholar
  24. D’Agostino RB Sr, Na BH (2004) Evaluation of the performance of survival analysis models: discrimination and calibration measures. In: Balakrishnan N, Rao C (eds) Advances in survival analysis: handbook of statistics, vol 23. Elsevier, Amsterdam
    Google Scholar
  25. Kanis JA, Black D, Cooper C, Dargent-Molina P, Dawson-Hughes B, De Laet C, Delmas P, Eisman J, Johnell O, Jonsson B, Melton L, Oden A, Papapoulos S, Pols H, Rizzoli R, Silman A, Tenenhouse A (2002) A new approach to the development of assessment guidelines for osteoporosis. Osteoporos Int 13:527–536
    Article PubMed CAS Google Scholar
  26. Robbins JA, Schott AM, Garnero P, Delmas PD, Hans D, Meunier PJ (2005) Risk factors for hip fracture in women with high BMD: EPIDOS study. Osteoporos Int 16:149–154
    Article PubMed CAS Google Scholar
  27. Hans D, Schott AM, Duboeuf F, Durosier C, Meunier PJ; on behalf of the EPIDOS Group (2004) Does follow-up duration influence the ultrasound and DXA prediction of hip fracture? The EPIDOS prospective study. Bone 35:357–363
    Article PubMed CAS Google Scholar
  28. Krieg MA, Cornuz J, Ruffieux C, Burckhardt P (2004) Rôle des ultrasons osseoux pour la prédiction du risque de fracture de la hanche chez la femme âgée de 70 ans ou plus : résultsts de l’étude SEMOF et comparaison avec les données de la littérature. Rev Med Suisse Rom 124:59–62
    PubMed Google Scholar
  29. Miller PD, Siris ES, Barrett-Connor E, Faulkner KG, Wehren LE, Abbott TA, Chen YT, Berger ML, Santora AC, Sherwood LM (2002) Prediction of fracture risk in postmenopausal white women with peripheral bone densitometry: evidence from the National Osteoporosis Risk Assessment. J Bone Miner Res 17:2222–2230
    Article PubMed Google Scholar
  30. Heaney RP (2003) Is the paradigm shifting? Bone 33:457–465
    Article PubMed Google Scholar
  31. Sedrine W, Devogelaer JP, Kaufman JM, Goemaere S, Depresseux G, Zegels B, Deroisy R, Reginster JY (2001) Evaluation of the simple calculated osteoporosis risk estimation (SCORE) in a sample of white women from Belgium. Bone 29:374–380
    Article PubMed Google Scholar
  32. Sedrine WB, Chevallier T, Zegels B, Kvasz A, Micheletti MC, Gelas B, Reginster JY (2002) Development and assessment of the Osteoporosis Index of Risk (OSIRIS) to facilitate selection of women for bone densitometry. Gynecol Endocrinol 16:245–250
    PubMed CAS Google Scholar
  33. Cadarette SM, Jaglal SB, Kreiger N, McIsaac WJ, Darlington GA, Tu JV (2000) Development and validation of the Osteoporosis Risk Assessment Instrument to facilitate selection of women for bone densitometry. CMAJ 162:1289–1294
    PubMed CAS Google Scholar
  34. Weinstein L, Ullery B (2000) Identification of at-risk women for osteoporosis screening. Am J Obstet Gynecol 183:547–549
    Article PubMed CAS Google Scholar
  35. Koh LK, Sedrine WB, Torralba TP, Kung A, Fujiwara S, Chan SP, Huang QR, Rajatanavin R, Tsai KS, Park HM, Reginster JY (2001) Osteoporosis Self-Assessment Tool for Asians (OSTA) Research Group. A simple tool to identify Asian women at increased risk of osteoporosis. Osteoporos Int 12:699–705
    Article PubMed CAS Google Scholar
  36. Albrand G, Muñoz F, Sornay-Rendu E, DuBoeuf F, Delmas PD (2003) Independent predictors of all osteoporosis-related fractures in healthy postmenopausal women: the OFELY study. Bone 32:78–85
    Article PubMed CAS Google Scholar
  37. Black DM, Steinbuch M, Palermo L, Dargent-Molina P, Lindsay R, Hoseyni MS, Johnell O (2001) An assessment tool for predicting fracture risk in postmenopausal women. Osteoporos Int 12:519–528
    Article PubMed CAS Google Scholar
  38. Barr RJ, Adebajo A, Fraser WD, Halsey JP, Kelsey C, Stewart A, Reid DM (2005) Can peripheral DXA measurements be used to predict fractures in elderly women living in the community?. Osteoporos Int 16:1177–1183
    Article PubMed CAS Google Scholar
  39. Kaptoge S, Benevolenskaya LI, Bhalla AK, Cannata JB, Boonen S, Falch JA, Felsenberg D, Finn JD, Nuti R, Hoszowski K, Lorenc R, Miazgowski T, Jajic I, Lyritis G, Masaryk P, Naves-Diaz M, Poor G, Reid DM, Scheidt-Nave C, Stepan JJ, Todd CJ, Weber K, Woolf AD, Roy DK, Lunt M, Pye SR, O’Neill TW, Silman AJ, Reeve J (2005) Low BMD is less predictive than reported falls for future limb fractures in women across Europe: results from the European Prospective Osteoporosis Study. Bone 36:387–398
    Article PubMed CAS Google Scholar
  40. Kanis JA, Johnell O, De Laet C, Johansson H, Oden A, Delmas P, Eisman J, Fujiwara S, Garnero P, Kroger H, McCloskey EV, Mellstrom D, Melton LJ, Pols H, Reeve J, Silman A, Tenenhouse A (2004) A meta-analysis of previous fracture and subsequent fracture risk. Bone 35:375–382
    Article PubMed CAS Google Scholar
  41. Kanis JA, Johansson H, Oden A, Johnell O, De Laet C, Eisman JA, McCloskey EV, Mellstrom D, Melton LJ 3rd, Pols HA, Reeve J, Silman AJ, Tenenhouse A (2004) A family history of fracture and fracture risk: a meta-analysis. Bone 35:1029–1037
    Article PubMed CAS Google Scholar
  42. Kanis JA, Johansson H, Oden A, De Laet C, Johnell O, Eisman JA, Mc Closkey E, Mellstrom D, Pols H, Reeve J, Silman A, Tenenhouse A (2005) A meta-analysis of milk intake and fracture risk: low utility for case finding. Osteoporos Int 16:799–804
    Article PubMed Google Scholar
  43. Bouxsein ML (2003) Bone quality: an old concept revisited. Osteoporos Int 14(Suppl 5):S1–S2
    Article PubMed Google Scholar
  44. Recker R, Lappe J, Davies KM, Heaney R (2004) Bone remodeling increases substantially in the years after menopause and remains increased in older osteoporosis patients. J Bone Miner Res 19:1628–1633
    Article PubMed Google Scholar
  45. Stauber M, Müller R (2006) Age-related changes in trabecular bone microstructures: global and local morphometry. Osteoporos Int 17:616–626
    Article PubMed CAS Google Scholar
  46. Turner CH (2002) Biomechanics of bone: determinants of skeletal fragility and bone quality. Osteoporosis Int 13:97–104
    Article CAS Google Scholar
  47. Wang X, Shen X, Li X, Mauli-Agrawal C (2002) Age-related changes in the collagen network and toughness of bone. Bone 31:1–7
    Article PubMed Google Scholar
  48. Wickham C, Cooper C, Margetts BM, Baker DJ (1989) Muscle strength, housing and the risk of falls in elderly people. Age Ageing 18:47–51
    Article PubMed CAS Google Scholar
  49. Ensrud KE, Duong T, Cauley JA, Heaney RP, Wolf RL, Harris E, Cummings SR (2000) Low fractional calcium absorption increases the risk for hip fracture in women with low calcium intake. Study of Osteoporotic Fractures Research Group. Ann Intern Med 132:345–353
    PubMed CAS Google Scholar
  50. Honkanen RJ, Honkanen K, Kroger H, Alhava E, Tuppurainen M, Saarikoski S (2000) Risk factors for perimenopausal distal forearm fracture. Osteoporos Int 11:265–270
    Article PubMed CAS Google Scholar
  51. Johnell O, Gullberg B, Kanis JA, Allander E, Elffors L, Dequeker J, Dilsen G, Gennari C, Lopes Vaz A, Lyritis G (1995) Risk factors for hip fracture in European women: the MEDOS Study. Mediterranean Osteoporosis Study. J Bone Miner Res 10:1802–1815
    Article PubMed CAS Google Scholar
  52. Feskanich D, Willett WC, Colditz GA (2003) Calcium, vitamin D, milk consumption, and hip fractures: a prospective study among postmenopausal women. Am J Clin Nutr 77:504–511
    PubMed CAS Google Scholar
  53. Dawson-Hughes B (2003) Interaction of dietary calcium and protein in bone health in humans. J Nutr 133:852S–854S
    PubMed CAS Google Scholar
  54. Kanis JA, Johnell O, Oden A, Johansson H, De Laet C, Eisman JA, Fujiwara S, Kroger H, McCloskey EV, Mellstrom D, Melton LJ, Pols H, Reeve J, Silman A, Tenenhouse A (2005) Smoking and fracture risk: a meta-analysis. Osteoporos Int 16:155–162
    Article PubMed CAS Google Scholar
  55. Johansson H, Oden A, Johnell O, Jonsson B, De Laet C, Oglesby A, McCloskey EV, Kayan K, Jalava T, Kanis JA (2004) Optimization of BMD measurements to identify high risk groups for treatment. A test analysis. J Bone Miner Res 19:906–913
    Article PubMed Google Scholar
  56. Cheng S, Hans D, Genant HK (1999) Calcaneal quantitative ultrasound systems: gel-coupled. In: Njeh CF, Hans D, Fuerst T, Glüer CC, Genant HK (eds) Quantitative ultrasound: assessment of osteoporosis and bone status. Martin Dunitz Ltd, London
    Google Scholar
  57. McGrother CW, Donaldson MMK, Clayton D, Abrams KR, Clarke M (2002) Evaluation of a hip fracture risk score for assessing elderly women: the Melton Osteoporotic Fracture (MOF) Study. Osteoporos Int 13:89–96
    Article PubMed CAS Google Scholar
  58. Burger H, de Laet CE, Weel AE, Hofman A, Pols HA (1999) Added value of bone mineral density in hip fracture risk scores. Bone 25:369–374
    Article PubMed CAS Google Scholar
  59. Dargent-Molina P, Douchin MN, Cormier C, Meunier PJ, Breart G; EPIDOS Study Group (2002) Use of clinical risk factors in elderly women with low bone mineral density to identify women at higher risk of hip fracture: the EPIDOS prospective study. Osteoporos Int 13:593–599
    Article PubMed CAS Google Scholar
  60. MedSurf’s Remaining Lifetime Fracture Probability. Available at: http://www.medsurf.com/RLFP_web_demo.php/. Accessed May 16, 2006
  61. Hip fracture risk calculator for healthy postmenopausal women. Available at: http://apps.sbgh.mb.ca/fracture/. Accessed May 16, 2006
  62. Ettinger B, Hillier TA, Pressman A, Che M, Hanley DA (2005) Simple computer model for calculating and reporting 5-year osteoporotic fracture risk in postmenopausal women. J Women Health 14:159–171
    Article Google Scholar
  63. Wilson PW, D’Agostino RB, Levy D, Belanger AM, Silbershatz H, Kannel WB (1998) Prediction of coronary heart disease using risk factor categories. Circulation 97:1837–1847
    PubMed CAS Google Scholar
  64. Conroy RM, Pyorala K, Fitzgerald AP, Sans S, Menotti A, De Backer G, De Bacquer D, Ducimetiere P, Jousilahti P, Keil U, Njolstad I, Oganov RG, Thomsen T, Tunstall-Pedoe H, Tverdal A, Wedel H, Whincup P, Wilhelmsen L, Graham IM, SCORE project group (2003) Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project. Eur Heart J 24:987–1003
    Article PubMed CAS Google Scholar
  65. Gail MH, Brinton LA, Byar DP, Corle DK, Green SB, Schairer C, Mulvihill JJ (1989) Projecting individualized probabilities of developing breast cancer for white females who are being examined annually. J Natl Cancer Inst 81:1879–1886
    Article PubMed CAS Google Scholar
  66. National Osteoporosis Foundation. Physician’s Guide to Prevention and Treatment of Osteoporosis. Available at: http://www.nof.org/professionals/clinical.htm/. Accessed May 16, 2006

Download references