Inappropriate prescribing for the elderly—a modern epidemic? (original) (raw)
Pirmohamed M, James S, Meakin S, Green C, Scott AK, Walley TJ, Farrar K, Park BK, Breckenridge AM (2004) Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients. BMJ 329(7456):15–19. doi:10.1136/bmj.329.7456.15 ArticlePubMed Google Scholar
Lazarou J, Pomeranz BH, Corey PN (1998) Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. JAMA 279(15):1200–1205 ArticlePubMedCAS Google Scholar
Ebbesen J, Buajordet I, Erikssen J, Brors O, Hilberg T, Svaar H, Sandvik L (2001) Drug-related deaths in a department of internal medicine. Arch Intern Med 161(19):2317–2323. doi:ioi00941 ArticlePubMedCAS Google Scholar
Viktil KK, Blix HS, Moger TA, Reikvam A (2007) Polypharmacy as commonly defined is an indicator of limited value in the assessment of drug-related problems. Br J Clin Pharmacol 63(2):187–195. doi:10.1111/j.1365-2125.2006.02744.x ArticlePubMed Google Scholar
Lapi F, Pozzi C, Mazzaglia G, Ungar A, Fumagalli S, Marchionni N, Geppetti P, Mugelli A, Di Bari M (2009) Epidemiology of suboptimal prescribing in older, community dwellers: a two-wave, population-based survey in Dicomano, Italy. Drugs Aging 26(12):1029–1038. doi:10.2165/11319390-000000000-00000 ArticlePubMed Google Scholar
Rønning M, Berg C, Furu K, Litleskare I, Mahic M, Sakshaug S, Selmer R, Strøm H (2009) The Norwegian Prescription Database 2004–2008. Norwegian Institute of Public Health, Oslo
Garfinkel D, Mangin D (2010) Feasibility study of a systematic approach for discontinuation of multiple medications in older adults: addressing polypharmacy. Arch Intern Med 170(18):1648–1654. doi:10.1001/archinternmed.2010.355 ArticlePubMed Google Scholar
Iyer S, Naganathan V, McLachlan AJ, Le Couteur DG (2008) Medication withdrawal trials in people aged 65 years and older: a systematic review. Drugs Aging 25(12):1021–1031. doi:10.2165/0002512-200825120-00004 ArticlePubMed Google Scholar
Hilmer SN, Mager DE, Simonsick EM, Cao Y, Ling SM, Windham BG, Harris TB, Hanlon JT, Rubin SM, Shorr RI, Bauer DC, Abernethy DR (2007) A drug burden index to define the functional burden of medications in older people. Arch Intern Med 167(8):781–787. doi:10.1001/archinte.167.8.781 ArticlePubMed Google Scholar
Grahame-Smith DG, Aronson JK (eds) (2002) Oxford textbook of clinical pharmacology and drug therapy, 3rd edn. Oxford University Press, Oxford
Fox C, Richardson K, Maidment ID, Savva GM, Matthews FE, Smithard D, Coulton S, Katona C, Boustani MA, Brayne C (2011) Anticholinergic medication use and cognitive impairment in the older population: the Medical Research Council Cognitive Function and Ageing Study. J Am Geriatr Soc 59(8):1477–1483. doi:10.1111/j.1532-5415.2011.03491.x ArticlePubMed Google Scholar
Aizenberg D, Sigler M, Weizman A, Barak Y (2002) Anticholinergic burden and the risk of falls among elderly psychiatric inpatients: a 4-year case-control study. Int Psychogeriatr 14(3):307–310 ArticlePubMed Google Scholar
Rudolph JL, Salow MJ, Angelini MC, McGlinchey RE (2008) The anticholinergic risk scale and anticholinergic adverse effects in older persons. Arch Intern Med 168(5):508–513. doi:10.1001/archinternmed.2007.106 ArticlePubMed Google Scholar
Page J, Henry D (2000) Consumption of NSAIDs and the development of congestive heart failure in elderly patients: an underrecognized public health problem. Arch Intern Med 160(6):777–784 ArticlePubMedCAS Google Scholar
Blix HS, Viktil KK, Moger TA, Reikvam A (2006) Use of renal risk drugs in hospitalized patients with impaired renal function–an underestimated problem? Nephrol Dial Transplant 21(11):3164–3171. doi:10.1093/ndt/gfl399 ArticlePubMed Google Scholar
Griffin MR, Piper JM, Daugherty JR, Snowden M, Ray WA (1991) Nonsteroidal anti-inflammatory drug use and increased risk for peptic ulcer disease in elderly persons. Ann Intern Med 114(4):257–263 PubMedCAS Google Scholar
Wang PS, Bohn RL, Glynn RJ, Mogun H, Avorn J (2001) Hazardous benzodiazepine regimens in the elderly: effects of half-life, dosage, and duration on risk of hip fracture. Am J Psychiatry 158(6):892–898 ArticlePubMedCAS Google Scholar
Pariente A, Dartigues JF, Benichou J, Letenneur L, Moore N, Fourrier-Reglat A (2008) Benzodiazepines and injurious falls in community dwelling elders. Drugs Aging 25(1):61–70 ArticlePubMedCAS Google Scholar
Dimitrow MS, Airaksinen MS, Kivela SL, Lyles A, Leikola SN (2011) Comparison of prescribing criteria to evaluate the appropriateness of drug treatment in individuals aged 65 and older: a systematic review. J Am Geriatr Soc 59(8):1521–1530. doi:10.1111/j.1532-5415.2011.03497.x ArticlePubMed Google Scholar
Beers MH (1997) Explicit criteria for determining potentially inappropriate medication use by the elderly. An update. Arch Intern Med 157(14):1531–1536 ArticlePubMedCAS Google Scholar
Fick DM, Cooper JW, Wade WE, Waller JL, Maclean JR, Beers MH (2003) Updating the Beers criteria for potentially inappropriate medication use in older adults: results of a US consensus panel of experts. Arch Intern Med 163(22):2716–2724. doi:10.1001/archinte.163.22.2716 ArticlePubMed Google Scholar
Beers MH, Ouslander JG, Rollingher I, Reuben DB, Brooks J, Beck JC (1991) Explicit criteria for determining inappropriate medication use in nursing home residents. UCLA Division of Geriatric Medicine. Arch Intern Med 151(9):1825–1832 ArticlePubMedCAS Google Scholar
Gallagher P, Ryan C, Byrne S, Kennedy J, O’Mahony D (2008) STOPP (Screening Tool of Older Person’s Prescriptions) and START (Screening Tool to Alert doctors to Right Treatment). Consensus validation. Int J Clin Pharmacol Ther 46(2):72–83 PubMedCAS Google Scholar
Aparasu RR, Mort JR (2000) Inappropriate prescribing for the elderly: Beers criteria-based review. Ann Pharmacother 34(3):338–346 ArticlePubMedCAS Google Scholar
van der Hooft CS, Jong GW, Dieleman JP, Verhamme KM, van der Cammen TJ, Stricker BH, Sturkenboom MC (2005) Inappropriate drug prescribing in older adults: the updated 2002 Beers criteria—a population-based cohort study. Br J Clin Pharmacol 60(2):137–144. doi:10.1111/j.1365-2125.2005.02391.x ArticlePubMed Google Scholar
Ryan C, O’Mahony D, Kennedy J, Weedle P, Byrne S (2009) Potentially inappropriate prescribing in an Irish elderly population in primary care. Br J Clin Pharmacol 68(6):936–947. doi:10.1111/j.1365-2125.2009.03531.x ArticlePubMed Google Scholar
Maio V, Del Canale S, Abouzaid S (2010) Using explicit criteria to evaluate the quality of prescribing in elderly Italian outpatients: a cohort study. J Clin Pharm Ther 35(2):219–229. doi:10.1111/j.1365-2710.2009.01094.x ArticlePubMedCAS Google Scholar
Fialova D, Topinkova E, Gambassi G, Finne-Soveri H, Jonsson PV, Carpenter I, Schroll M, Onder G, Sorbye LW, Wagner C, Reissigova J, Bernabei R, Ad HOC PRG (2005) Potentially inappropriate medication use among elderly home care patients in Europe. JAMA 293(11):1348–1358 ArticlePubMedCAS Google Scholar
Straand J, Rokstad KS (1999) Elderly patients in general practice: diagnoses, drugs and inappropriate prescriptions. A report from the More & Romsdal Prescription Study. Fam Pract 16(4):380–388 ArticlePubMedCAS Google Scholar
Zhan C, Sangl J, Bierman AS, Miller MR, Friedman B, Wickizer SW, Meyer GS (2001) Potentially inappropriate medication use in the community-dwelling elderly: findings from the 1996 Medical Expenditure Panel Survey. [See comment]. JAMA 286(22):2823–2829 ArticlePubMedCAS Google Scholar
Brekke M, Rognstad S, Straand J, Furu K, Gjelstad S, Bjorner T, Dalen I (2008) Pharmacologically inappropriate prescriptions for elderly patients in general practice: how common? Baseline data from The Prescription Peer Academic Detailing (Rx-PAD) study. Scand J Prim Health Care 26(2):80–85 ArticlePubMed Google Scholar
Carey IM, De Wilde S, Harris T, Victor C, Richards N, Hilton SR, Cook DG (2008) What factors predict potentially inappropriate primary care prescribing in older people? Analysis of UK primary care patient record database. Drugs Aging 25(8):693–706. doi:2586 ArticlePubMed Google Scholar
Hamilton H, Gallagher P, Ryan C, Byrne S, O’Mahony D (2011) Potentially inappropriate medications defined by STOPP criteria and the risk of adverse drug events in older hospitalized patients. Arch Intern Med 171(11):1013–1019. doi:10.1001/archinternmed.2011.215 ArticlePubMed Google Scholar
Stockl KM, Le L, Zhang S, Harada AS (2010) Clinical and economic outcomes associated with potentially inappropriate prescribing in the elderly. Am J Manag Care 16(1):e1–e10 PubMed Google Scholar
Rognstad S, Brekke M, Fetveit A, Spigset O, Wyller TB, Straand J (2009) The Norwegian General Practice (NORGEP) criteria for assessing potentially inappropriate prescriptions to elderly patients. A modified Delphi study. Scand J Prim Health Care 27(3):153–159. doi:10.1080/02813430902992215 ArticlePubMed Google Scholar
Furu K (2008) Establishment of the nationwide Norwegian Prescription Database (NorPD)—new opportunities for research in pharmacoepidemiology in Norway. Nor Epidemiol 18(2):129–136 Google Scholar
WHO Collaborating Centre for Drug Statistics Methodology and The Norwegian Institute of Public Health (2011) ATC/DDD Index. http://www.whocc.no/atc_ddd_index/. Accessed March 24, 2011
Budnitz DS, Shehab N, Kegler SR, Richards CL (2007) Medication use leading to emergency department visits for adverse drug events in older adults. Ann Intern Med 147(11):755–765 PubMed Google Scholar
Mattison ML, Afonso KA, Ngo LH, Mukamal KJ (2010) Preventing potentially inappropriate medication use in hospitalized older patients with a computerized provider order entry warning system. Arch Intern Med 170(15):1331–1336. doi:10.1001/archinternmed.2010.244 ArticlePubMed Google Scholar