Cyanobactins—ribosomal cyclic peptides produced by cyanobacteria (original) (raw)

• Admi V, Afek U, Carmeli S (1996) Raocyclamides A and B, novel cyclic hexapeptides isolated from the cyanobacterium Oscillatoria raoi. J Nat Prod 59:396–399
  Article CAS Google Scholar
• Arrault A, Witczak-Legrand A, Gonzalez P, Bontemps-Subielos N, Banaigs B (2002) Structure and total synthesis of cyclodidemnamide B, a cycloheptapeptide from the ascidian Didemnum molle. Tetrahedron Lett 43:4041–4044
  Article CAS Google Scholar
• Banker R, Carmeli S (1998) Tenuecyclamides A–D, cyclic hexapeptides from the cyanobacterium Nostoc spongiaeforme var. tenue. J Nat Prod 61:1248–1251
  Article CAS Google Scholar
• Baumann HI, Keller S, Wolter FE, Nicholson GJ, Jung G, Susmuth RD, Jüttner F (2007) Planktocyclin, a cyclooctapeptide protease inhibitor produced by the freshwater cyanobacterium Planktothrix rubescens. J Nat Prod 70:1611–1615
  Article CAS Google Scholar
• Berg KA, Lyra C, Sivonen K, Paulin L, Suomalainen S, Tuomi P, Rapala J (2009) High diversity of cultivable heterotrophic bacteria in association with cyanobacterial water blooms. ISME Journal 3:314–325
  Article CAS Google Scholar
• Bokesch HR, O'Keefe BR, McKee TC, Pannell LK, Patterson GML, Gardellina RS II, Sowder RC, Turpin J, Watson K, Buckheit RW Jr, Boyd MR (2003) A potent novel anti-HIV protein from the cultured cyanobacterium Scytonema varium. Biochemistry 42:2578–2584
  Article CAS Google Scholar
• Boyd MR, Gustafson KR, McMahon JB, Shoemaker RH, O'Keefe BR, Mori T, Gulakowski RJ, Wu L, Rivera MI, Laurencot CM, Currens MJ, Cardellina JH 2nd, Buckheit RW Jr, Nara PL, Pannell LK, Sowder RC 2nd, Henderson LE (1997) Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp 120: potential applications to microbicide development. Antimicrob Agents Chemother 42:1521–1530
  Google Scholar
• Burja AM, Bagnais B, Abou-Mansour E, Burgess JG, Wright PC (2001) Marine cyanobacteria—a prolific source of natural products. Tetrahedron 57:9347–9377
  Article CAS Google Scholar
• Caba JM, Rodriguez IM, Manzanares I, Giralt E, Albericio F (2001) Solid-phase total synthesis of trunkamide A1. J Org Chem 66:7568–7574
  Article CAS Google Scholar
• Degnan BM, Hawkins CJ, Lavin MF, McCaffrey EJ, Parry DL, van den Brenk AL, Watters DJ (1989a) New cyclic peptides with cytotoxic activity from the ascidian Lissoclinum patella. J Med Chem 32:1349–1354
  Article CAS Google Scholar
• Degnan BM, Hawkins CJ, Lavin MF, McCaffrey EJ, Parry DL, Watters DJ (1989b) Novel cytotoxic compounds from the ascidian Lissoclinum bistratum. J Med Chem 32:1354–1359
  Article CAS Google Scholar
• Donia MS, Hathaway BJ, Sudek S, Haygood MG, Rosovitz MJ, Ravel J, Schmidt EW (2006) Natural combinatorial peptide libraries in cyanobacterial symbionts of marine ascidians. Nat Chem Biol 2:729–735
  Article CAS Google Scholar
• Donia MS, Ravel J, Schmidt EW (2008a) A global assembly line for cyanobactins. Nat Chem Biol 4:341–343
  Article CAS Google Scholar
• Donia MS, Wang B, Dunbar DC, Desai PV, Pathy A, Avery M, Hamann MT (2008b) Mollamides B and C, cyclic hexapeptides from the Indonesian tunicate Didemnum molle. J Nat Prod 71:941–945
  Article CAS Google Scholar
• Foster MP, Ireland CM (1993) Nairaiamide A and nairaiamide B—2 novel di-proline heptapeptides isolated from a Fijian Lissoclinum-Bistratum ascidian. Tetrahedron Lett 34:2871–2874
  Article CAS Google Scholar
• Foster MP, Concepción GP, Caraan GB, Ireland CM (1992) Bistratamides C and D. Two new oxazole-containing cyclic hexapeptides isolated from a Philippine Lissoclinum bistratum ascidian. J Org Chem 57:6671–6675
  Article CAS Google Scholar
• Franz CMAP, van Belkum MJ, Holzapfel WH, Abriouel H, Galvez A (2007) Diversity of enterococcal bacteriocins and their grouping in a new classification scheme. FEMS Microbiol Rev 31:293–310
  Article CAS Google Scholar
• Fu X, Do T, Schmitz FJ, Andrusevich V, Engel MH (1998) New cyclic peptides from the ascidian Lissoclinum patella. J Nat Prod 61:1547–1551
  Article CAS Google Scholar
• Fujii K, Sivonen K, Naganawa E, Harada KI (2000) Non-toxic peptides from toxic cyanobacteria, Oscillatoria agardhii. Tetrahedron 56:725–733
  Article CAS Google Scholar
• Gesner-Apter S, Carmeli S (2008) Three novel metabolites from a bloom of the cyanobacterium Microcystis sp. Tetrahedron 64:6628–6634
  Article CAS Google Scholar
• Guan LL, Sera Y, Adachi K, Nishida F, Shizuri Y (2001) Isolation and evaluation of nonsiderophore cyclic peptides from marine sponges. Biochem Biophys Res Commun 283:976–981
  Article CAS Google Scholar
• Hambley TW, Hawkins CJ, Lavin MF, van den Brenk A, Watters DJ (1992) Cycloxazoline: a cytotoxic cyclic hexapeptide from the ascidian Lissoclinum bistratum. Tetrahedron 48:341–348
  Article CAS Google Scholar
• Hawkins CJ, Lavin MF, Marshall KA, van den Brenk AL, Watters DJ (1990) Structure–activity relationships of the lissoclinamides: cytotoxic cyclic peptides from the ascidian Lissoclinum patella. J Med Chem 33:1634–1638
  Article CAS Google Scholar
• Ireland CM, Scheuer PJ (1980) Ulicyclamide and ulithiacyclamide, two new small peptides from a marine tunicate. J Am Chem Soc 102:5688–5691
  Article CAS Google Scholar
• Ireland CM, Durso AR Jr, Newman RA, Hacker MP (1982) Antineoplastic cyclic peptides from the marine tunicate Lissoclinum patella. J Org Chem 47:1807–1811
  Article CAS Google Scholar
• Ishida T, Tanaka M, Nabae M, Inoue M (1988) Solution and solid-state conformations of ascidiacyclamide, a cytotoxic cyclic peptide from ascidian. J Org Chem 53:107–112
  Article CAS Google Scholar
• Ishida K, Matsuda H, Murakami M, Yamaguchi K (1996) Kawaguchipeptin A, a novel cyclic undecapeptide from cyanobacterium Microcystis aeruginosa (NIES-88). Tetrahedron 52:9025–9030
  Article CAS Google Scholar
• Ishida K, Matsuda H, Murakami M, Yamaguchi K (1997) Kawaguchipeptin B, an antibacterial cyclic undecapeptide from the cyanobacterium Microcystis aeruginosa. J Nat Prod 60:724–726
  Article CAS Google Scholar
• Ishida K, Nakagawa H, Murakami M (2000) Microcyclamide, a cytotoxic cyclic hexapeptide from the cyanobacterium Microcystis aeruginosa. J Nat Prod 63:1315–1317
  Article CAS Google Scholar
• Jack RW, Jung G (2000) Lantibiotics and microcins: polypeptides with unusual chemical diversity. Curr Opin Chem Biol 4:310–317
  Article CAS Google Scholar
• Jack RW, Tagg JR, Ray B (1995) Bacteriocins of Gram-positive bacteria. Microbiol Rev 59:171–200
  CAS Google Scholar
• Jüttner F, Todorova AK, Walch N, von Philipsborn W (2001) Nostocyclamide M: a cyanobacterial cyclic peptide with allelopathic activity from Nostoc 31. Phytochemistry 57:613–619
  Article Google Scholar
• Kobayashi J, Tsuda M, Nakamura T, Mikami Y, Shigemori H (1993) Hymenamide A and hymenamide B, new proline-rich cyclic heptapeptides from the Okinawan marine sponge Hymeniacidon sp. Tetrahedron 49:2391–2402
  Article CAS Google Scholar
• Lee SW, Mitchell DA, Markley AL, Hensler ME, Gonzalez D, Wohlrab A, Dorrestein PC, Nizet V, Dixon JE (2008) Discovery of a widely distributed toxin biosynthetic gene cluster. Proc Natl Acad Sci U S A 105:5879–5884
  Article CAS Google Scholar
• Lee J, McIntosh J, Hathaway BJ, Schmidt EW (2009) Using marine natural products to discover a protease that catalyses peptide macrocyclization of diverse substrates. J Am Chem Soc 131:2122–2124
  Article CAS Google Scholar
• Leikoski N, Fewer DP, Sivonen K (2009) Widespread occurrence and lateral transfer of the cyanobactin biosynthesis gene cluster in cyanobacteria. Appl Environ Microbiol 75:853–857
  Article CAS Google Scholar
• Leikoski N, Fewer DP, Jokela J, Wahlsten M, Rouhiainen L, Sivonen K (2010) Highly diverse cyanobactins in strains of the genus Anabaena. Appl Environ Microbiol 76:701–709
  Article CAS Google Scholar
• Li WL, Yi YH, Wu HM, Xu QZ, Tang HF, Zhou DZ, Lin HW, Wang ZH (2003) Isolation and structure of the cytotoxic cycloheptapeptide phakellistatin 13. J Nat Prod 66:146–148
  Article CAS Google Scholar
• Linington RG, Gonzàles J, Ureña L-D, Romero LI, Ortega-Barria E, Gerwick WH (2007) Venturamides A and B: antimalarial constituents of the Panamanian marine cyanobacterium Oscillatoria sp. J Nat Prod 70:397–401
  Article CAS Google Scholar
• Manage PM, Kawabata Z, Nakano S-I (2000) Algicidal effect of the bacterium Alcaligenes denitrificans on Microcystis spp. Aquat Microb Ecol 22:111–117
  Article Google Scholar
• Maqueda M, Sanchez-Hidalgo M, Fernandez M, Montalban-Lopez M, Valdivia E, Martinez-Bueno M (2008) Genetic features of circular bacteriocins produced by Gram-positive bacteria. FEMS Microbiol Rev 32:2–22
  Article CAS Google Scholar
• Martin-Visscher LA, Gong XD, Duszyk M, Vederas JC (2009) The three-dimensional structure of carnocyclin A reveals that many circular bacteriocins share a common structural motif. J Biol Chem 284:28674–28681
  Article CAS Google Scholar
• McDonald LA, Ireland CM (1992) Patellamide E: a new cyclic peptide from the ascidian Lissoclinum patella. J Nat Prod 55:376–379
  Article CAS Google Scholar
• McDonald LA, Foster MP, Phillips DR, Ireland CM, Lee AY, Clardy J (1992) Tawicyclamides A and B, new cyclic peptides from the ascidian Lissoclinum patella: studies on the solution- and solid-state conformations. J Org Chem 57:4616–4624
  Article CAS Google Scholar
• McKeever B, Pattenden G (2003) Total synthesis of the cytotoxic cyclopeptide mollamide, isolated from the sea squirt Didemnum molle. Tetrahedron 59:2701–2712
  Google Scholar
• Milanowski DJ, Rashid MA, Gustafson KR, O'Keefe BR, Nawrocki JP, Pannell LK, Boyd MR (2004) Cyclonellin, a new cyclic octapeptide from the marine sponge Axinella carteri. J Nat Prod 67:441–444
  Article CAS Google Scholar
• Mitchell SS, Faulkner DJ, Rubins K, Bushman FD (2000) Dolastatin 3 and two novel cyclic peptides from a Palauan collection of Lyngbya majuscula. J Nat Prod 63:279–282
  Article CAS Google Scholar
• Mohammed R, Peng J, Kelly M, Hamann MT (2006) Cyclic heptapeptides from the Jamaican sponge Stylissa caribica. J Nat Prod 69:1739–1744
  Article CAS Google Scholar
• Morris LA, van den Bosch JJK, Versluis K, Thompson GS, Jaspars M (2000) Structure determination and MSn analysis of two new lissoclinamides isolated from the Indo-Pacific ascidian Lissoclinum patella: NOE restrained molecular dynamics confirms the absolute stereochemistry derived by degradative methods. Tetrahedron 56:8345–8353
  Article CAS Google Scholar
• Murakami M, Itou Y, Ishida K, Shin HJ (1999) Prenylagaramides A and B, new cyclic peptides from two strains of Oscillatoria agardhii. J Nat Prod 62:752–755
  Article CAS Google Scholar
• Napolitano A, Bruno I, Rovero P, Lucas R, Peris MP, Gomez-Paloma L, Riccio R (2001) Synthesis, structural aspects and bioactivity of the marine cyclopeptide hymenamide C. Tetrahedron 57:6249–6255
  Article CAS Google Scholar
• Nogle LM, Marquez BL, Gerwick WH (2003) Wewakazole, a novel cyclic dodecapeptide from a Papua New Guinea Lyngbya majuscula. Org Lett 5:3–6
  Article CAS Google Scholar
• Nolan EM, Walsh CT (2009) How nature morphs peptide scaffolds into antibiotics. ChemBioChem 10:34–53
  Article CAS Google Scholar
• Ogino J, Moore RE, Patterson GML, Smith CD (1996) Dendroamides, new cyclic hexapeptides from blue-green alga. Multidrug-resistance reversing activity of dendroamide A. J Nat Prod 59:581–586
  Article CAS Google Scholar
• Ojika M, Nemoto T, Nakamura M, Yamada K (1995) Dolastatin E, a new cyclic hexapeptide isolated from the sea hare Dolabella-auricularia. Tetrahedron Lett 36:5057–5058
  CAS Google Scholar
• Oman TJ, van der Donk WA (2010) Follow the leader: the use of leader peptides to guide natural product biosynthesis. Nat Chem Biol 6:9–18
  Article CAS Google Scholar
• Perez LJ, Faulkner DJ (2003) Bistratamides E–J, modified cyclic hexapeptides from the Philippines ascidian Lissoclinum bistratum. J Nat Prod 66:247–250
  Article CAS Google Scholar
• Pettit GR, Tan R (2003) Antineoplastic agents 390. Isolation and structure of phakellistatin 12 from a Chuuk archipelago marine sponge. Bioorg Med Chem Lett 13:685–688
  Article CAS Google Scholar
• Pettit GR, Cichacz Z, Barkoczy J, Dorsaz AC, Herald DL, Williams MD, Doubek DL, Schmidt JM, Tackett LP, Brune DC, Cerny RL, Hooper JNA, Bakus GJ (1993a) Antineoplastic agents. 249. Isolation and structure of the marine sponge cell-growth inhibitory cyclic peptide phakellistatin 1. J Nat Prod 56:260–267
  Article CAS Google Scholar
• Pettit GR, Tan R, Williams MD, Tackett L, Schmidt JM, Cerny RL, Hooper JNA (1993b) Isolation and structure of phakellistatin 2 from the eastern Indian-ocean marine Sponge Phakellia carteri. Bioorg Med Chem Lett 3:2869–2874
  Article CAS Google Scholar
• Pettit GR, Gao F, Cerny RL, Doubek DL, Tackett LP, Schmidt JM, Chapuis JC (1994) Antineoplastic agents. 278. Isolation and structure of axinastatin 2 and axinastatin 3 from a western Caroline island marine sponge. J Med Chem 37:1165–1168
  Article CAS Google Scholar
• Pettit GR, Xu JP, Dorsaz AC, Williams MD, Boyd MR, Cerny RL (1995) Antineoplastic agents series contribution. 324. Isolation and structure of the human cancer cell-growth inhibitory cyclic decapeptides phakellistatin 7, phakellistatin 8 and phakellistatin 9. Bioorg Med Chem Lett 5:1339–1344
  Article CAS Google Scholar
• Philmus B, Christiansen G, Yoshida WY, Hemscheidt TK (2008) Post-translational modification in microviridin biosynthesis. ChemBioChem 9:3066–3073
  Article CAS Google Scholar
• Ploutno A, Carmeli S (2002) Modified peptides from a water bloom of the cyanobacterium Nostoc sp. Tetrahedron 58:9949–9957
  Article CAS Google Scholar
• Portmann C, Blom JF, Gademann K, Jüttner F (2008a) Aerucyclamides A and B: isolation and synthesis of toxic ribosomal heterocyclic peptides from the cyanobacterium Microcystis aeruginosa PCC 7806. J Nat Prod 71:1193–1196
  Article CAS Google Scholar
• Portmann C, Blom JF, Kaiser M, Brun R, Jüttner F, Gademann K (2008b) Isolation of aerucyclamides C and D and structure revision of microcyclamide 7806A: heterocyclic ribosomal peptides from Microcystis aeruginosa PCC 7806 and their antiparasite evaluation. J Nat Prod 71:1891–1896
  Article CAS Google Scholar
• Prinsep MR, Moore RE, Levine IA, Patterson GML (1992) Westiellamide, a bistratamide-related cyclic peptide from the blue-green alga Westiellopsis prolifica. J Nat Prod 55:140–142
  Article CAS Google Scholar
• Rashid MA, Gustafson KR, Cardellina JH II, Boyd MR (1995) Patellamide F, a new cytotoxic cyclic peptide from the colonial ascidian Lissoclinum patella. J Nat Prod 58:594–597
  Article CAS Google Scholar
• Rouhiainen L, Paulin L, Suomalainen S, Hyytiäinen H, Buikema W, Haselkorn H, Sivonen K (2000) Genes encoding synthetases of cyclic depsipeptides, anabaenopeptilides, in Anabaena strain 90. Molecular Microbiol 37:156–167
  Article CAS Google Scholar
• Rudi A, Aknin M, Gaydou EM, Kashman Y (1998) Four new cytotoxic cyclic hexa- and heptapeptides from the marine ascidian Didemnum molle. Tetrahedron 54:13203–13210
  Article CAS Google Scholar
• Rudi A, Chill L, Aknin M, Kashman Y (2003) Didmolamide A and B, two new cyclic hexapeptides from the marine ascidian Didemnum molle. J Nat Prod 66:575–577
  Article CAS Google Scholar
• Salvatella X, Caba JM, Albericio F, Giralt E (2003) Solution structure of the antitumor candidate trunkamide A by 2D NMR and restrained simulated annealing methods. J Org Chem 68:211–215
  Article CAS Google Scholar
• Schmidt EW, Donia MS (2009) Cyanobactin ribosomally synthesized peptides—a case of deep metagenome mining. Meth Enzymol 458:575–596
  Article CAS Google Scholar
• Schmidt EW, Nelson JT, Rasko DA, Sudek S, Eisen JA, Haygood MG, Ravel J (2005) Patellamide A and C biosynthesis by a microcin-like pathway in Prochloron didemni, the cyanobacterial symbiont of Lissoclinum patella. Proc Natl Acad Sci U S A 102:7315–7320
  Article CAS Google Scholar
• Schmidt G, Grube A, Kock M (2007) Stylissamides A–D—new proline-containing cyclic heptapeptides from the marine sponge Stylissa caribica. European J Org Chem 24:4103–4110
  Article Google Scholar
• Schmitz FJ, Ksebati MB, Chang JS, Wang JL, Hossain MB, van der Helm D (1989) Cyclic peptides from the ascidian Lissoclinum patella: conformational analysis of patellamide D by X-ray analysis and molecular modelling. J Org Chem 54:3463–3472
  Article CAS Google Scholar
• Sera Y, Adachi K, Fujii K, Shizuri Y (2003) A new antifouling hexapeptide from a Palauan sponge, Haliclona sp. J Nat Prod 66:719–721
  Article CAS Google Scholar
• Shin HJ, Matsuda H, Murakami M, Yamaguchi K (1996) Agardhipeptins A and B, two new cyclic hepta- and octapeptide, from the cyanobacterium Oscillatoria agardhii (NIES-204). Tetrahedron 52:13129–13136
  Article CAS Google Scholar
• Sings HL, Rinehart KL (1996) Compounds produced from potential tunicate-blue-green algal symbiosis: a review. J Ind Microbiol Biotechnol 17:385–396
  Article CAS Google Scholar
• Sivonen K, Börner T (2008) Bioactive compounds produced by cyanobacteria. In: Herraro A, Flores E (eds) The cyanobacteria: molecular biology, genomics and evolution. Caister Academic, Norfolk, pp 159–197
  Google Scholar
• Sone H, Kigoshi H, Yamada K (1997) Isolation and stereostructure of dolastatin I, a cytotoxic cyclic hexapeptide from the Japanese sea hare Dolabella auricularia. Tetrahedron 53:8149–8154
  Article CAS Google Scholar
• Sudek S, Haygood MG, Youssef DTA, Schmidt EW (2006) Structure of trichamide, a cyclic peptide from the bloom-forming cyanobacterium Trichodesmium erythraeum, predicted from the genome sequence. Appl Environ Microbiol 72:4382–4387
  Article CAS Google Scholar
• Tabudravu J, Morris LA, Kettenes-van den Bosch JJ, Jaspars M (2001) Wainunuamide, a histidine-containing proline-rich cyclic heptapeptide isolated from the Fijian marine sponge Stylotella aurantium. Tetrahedron Lett 42:9273–9276
  Article CAS Google Scholar
• Tabudravu JN, Morris LA, Kettenes-van den Bosch JJ, Jaspars M (2002a) Axinellin C, a proline-rich cyclic octapeptide isolated from the Fijian marine sponge Stylotella aurantium. Tetrahedron 58:7863–7868
  Article CAS Google Scholar
• Tabudravu JN, Jaspars M, Morris LA, Kettenes-van den Bosch JJ, Smith N (2002b) Two distinct conformers of the cyclic heptapeptide phakellistatin 2 isolated from the Fijian marine sponge Stylotella aurantium. J Org Chem 67:8593–8601
  Article CAS Google Scholar
• Teruya T, Sasaki H, Suenaga K (2008) Hexamollamide, a hexapeptide from an Okinawan ascidian Didemnum molle. Tetrahedron Lett 49:5297–5299
  Article CAS Google Scholar
• Tillett D, Dittmann E, Erhard M, von Döhren H, Börner T, Neilan BA (2000) Structural organization of microcystin biosynthesis in Microcystin aeruginosa PCC7806: an integrated peptide-polyketide synthetase system. Chem Biol 7:753–764
  Article CAS Google Scholar
• Todorova AK, Jüttner F, Linden A, Plüss T, von Philipsborn W (1995) Nostocyclamide: a new macrocyclic, thiazole-containing allelochemical from Nostoc sp. 31 (cyanobacteria). J Org Chem 60:7891–7895
  Article CAS Google Scholar
• Toske SG, Fenical W (1995) Cyclodidemnamide—a new cyclic heptapeptide from the marine ascidian Didemnum molle. Tetrahedron Lett 36:8355–8358
  Article CAS Google Scholar
• Tsuda M, Sasaki T, Kobayashi J (1994) Hymenamide G, hymenamide H, hymenamide J, and hymenamide-K, 4 new cyclic octapeptides from the Okinawan marine sponge Hymeniacidon sp. Tetrahedron 50:4667–4680
  Article CAS Google Scholar
• Wasylyk JM, Biskupiak JE, Costello CE, Ireland CM (1983) Cyclic peptide structures from the tunicate Lissoclinum patella by FAB mass spectrometry. J Org Chem 48:4445–4449
  Article CAS Google Scholar
• Welker M, von Döhren H (2006) Cyanobacterial peptides—nature's own combinatorial biosynthesis. FEMS Microbiol Rev 30:530–563
  Article CAS Google Scholar
• Williams DE, Moore RE, Paul VJ (1989) The structure of ulithiacyclamide B. Antitumor evaluation of cyclic peptides and macrolides from Lissoclinum patella. J Nat Prod 52:732–739
  Article CAS Google Scholar
• Zabriskie TM, Foster MP, Stout TJ, Clardy J, Ireland CM (1990) Studies on the solution- and solid-state structure of patellin 2. J Am Chem Soc 112:8080–8084
  Article CAS Google Scholar
• Ziemert N, Ishida K, Liaimer A, Hertweck C, Dittmann E (2008a) Ribosomal synthesis of tricyclic depsipeptides in bloom-forming cyanobacteria. Angew Chem Int Ed 47:7756–7759
  Article CAS Google Scholar
• Ziemert N, Ishida K, Quillardet P, Bouchier C, Hertweck C, Tandeau de Marsac N, Dittmann E (2008b) Microcyclamide biosynthesis in two strains of Microcystis aeruginosa: from structure to genes and vice versa. Appl Environ Microbiol 74:1791–1797
  Article CAS Google Scholar