Long-term impacts of appendectomy associated with increased incidence of inflammatory bowel disease, infection, and colorectal cancer (original) (raw)

References

  1. Noudeh YJ, Sadigh N, Ahmadnia AY (2007) Epidemiologic features, seasonal variations and false positive rate of acute appendicitis in Shahr-e-Rey, Tehran. Int J Surg 5(2):95–98
    Article Google Scholar
  2. Andersson RE (2007) The natural history and traditional management of appendicitis revisited: spontaneous resolution and predominance of prehospital perforations imply that a correct diagnosis is more important than an early diagnosis. World J Surg 31(1):86–92
    Article Google Scholar
  3. Salminen P, Tuominen R, Paajanen H, Rautio T, Nordström P, Aarnio M, Rantanen T, Hurme S, Mecklin JP, Sand J, Virtanen J, Jartti A, Grönroos JM (2018) Five-year follow-up of antibiotic therapy for uncomplicated acute appendicitis in the APPAC randomized clinical trial. JAMA 320(12):1259–1265
    Article CAS Google Scholar
  4. Salminen P, Paajanen H, Rautio T, Nordström P, Aarnio M, Rantanen T, Tuominen R, Hurme S, Virtanen J, Mecklin JP, Sand J, Jartti A, Rinta-Kiikka I, Grönroos JM (2015) Antibiotic therapy vs appendectomy for treatment of uncomplicated acute appendicitis: the APPAC randomized clinical trial. JAMA 313(23):2340–2348
    Article CAS Google Scholar
  5. Addiss DG, Shaffer N, Fowler BS, Tauxe RV (1990) The epidemiology of appendicitis and appendectomy in the United States. Am J Epidemiol 132(5):910–925
    Article CAS Google Scholar
  6. Randal Bollinger R, Barbas AS, Bush EL, Lin SS, Parker W (2007) Biofilms in the large bowel suggest an apparent function of the human vermiform appendix. J Theor Biol 249(4):826–831
    Article CAS Google Scholar
  7. Zahid A (2004) The vermiform appendix: not a useless organ. J Coll Physicians Surg Pak 14(4):256–258
    PubMed Google Scholar
  8. Fujihashi K, McGhee JR, Lue C, Beagley KW, Taga T, Hirano T, Kishimoto T, Mestecky J, Kiyono H (1991) Human appendix B cells naturally express receptors for and respond to interleukin 6 with selective IgA1 and IgA2 synthesis. J Clin Invest 88(1):248–252
    Article CAS Google Scholar
  9. Palestrant D, Holzknecht ZE, Collins BH, Parker W, Miller SE, Bollinger RR (2004) Microbial biofilms in the gut: visualization by electron microscopy and by acridine orange staining. Ultrastruct Pathol 28(1):23–27
    Article Google Scholar
  10. Sonnenburg JL, Angenent LT, Gordon JI (2004) Getting a grip on things: how do communities of bacterial symbionts become established in our intestine? Nat Immunol 5(6):569–573
    Article CAS Google Scholar
  11. Bjerke K, Brandtzaeg P, Rognum TO (1986) Distribution of immunoglobulin producing cells is different in normal human appendix and colon mucosa. Gut 27(6):667–674
    Article CAS Google Scholar
  12. Andersson RE, Olaison G, Tysk C, Ekbom A (2003) Appendectomy is followed by increased risk of Crohn’s disease. Gastroenterology 124(1):40–46
    Article Google Scholar
  13. Kaplan GG, Jackson T, Sands BE, Frisch M, Andersson RE, Korzenik J (2008) The risk of developing Crohn’s disease after an appendectomy: a meta-analysis. Am J Gastroenterol 103(11):2925–2931
    Article Google Scholar
  14. Frisch M, Pedersen BV, Andersson RE (2009) Appendicitis, mesenteric lymphadenitis, and subsequent risk of ulcerative colitis: cohort studies in Sweden and Denmark. BMJ 338:b716
    Article Google Scholar
  15. Radford-Smith GL (2008) What is the importance of appendectomy in the natural history of IBD? Inflamm Bowel Dis 14:S72–S74
    Article Google Scholar
  16. Merchant R, Mower WR, Ourian A, Abrahamian FM, Moran GJ, Krishnadasan A, Talan DA (2012) Association between appendectomy and Clostridium difficile infection. J Clin Med Res 4(1):17–19
    PubMed PubMed Central Google Scholar
  17. Andersson RE, Olaison G, Tysk C, Ekbom A (2001) Appendectomy and protection against ulcerative colitis. N Engl J Med 344(11):808–814
    Article CAS Google Scholar
  18. Song SO, Jung CH, Song YD, Park CY, Kwon HS, Cha BS, Park JY, Lee KU, Ko KS, Lee BW (2014) Background and data configuration process of a nationwide population-based study using the Korean national health insurance system. Diabetes Metab J 38(5):395–403
    Article Google Scholar
  19. Quan H, Sundararajan V, Halfon P, Fong A, Burnand B, Luthi JC, Saunders LD, Beck CA, Feasby TE, Ghali WA (2005) Coding algorithms for defining comorbidities in ICD-9-CM and ICD-10 administrative data. Med Care 43(11):1130–1139
    Article Google Scholar
  20. Oh SY, Cho S, Kim GH, Jang EJ, Choi S, Lee H, Ryu HG (2019) Incidence and Outcomes Of Sepsis in Korea: a nationwide cohort study from 2007 to 2016. Crit Care Med 47(12):e993–e998
    Article Google Scholar
  21. Austin PC (2009) Using the standardized difference to compare the prevalence of a binary variable between two groups in observational research. Commun Stat Simul Comput 38(6):1228–1234
    Article Google Scholar
  22. Fine JP, Gray RJ (1999) A proportional hazards model for the subdistribution of a competing risk. J Am Stat Assoc 94(446):496–509
    Article Google Scholar
  23. Gray RJ (1988) A class of K-sample tests for comparing the cumulative incidence of a competing risk. Ann Stat 16(3):1141–1154
    Article Google Scholar
  24. Girard-Madoux MJH, Gomez de Aguero M, Ganal-Vonarburg SC, Mooser C, Belz GT, Macpherson AJ, Vivier E (2018) The immunological functions of the appendix: an example of redundancy? Semin Immunol 36:31–44
    Article CAS Google Scholar
  25. Loh G, Blaut M (2012) Role of commensal gut bacteria in inflammatory bowel diseases. Gut Microbes 3(6):544–555
    Article Google Scholar
  26. Bien J, Palagani V, Bozko P (2013) The intestinal microbiota dysbiosis and Clostridium difficile infection: is there a relationship with inflammatory bowel disease? Ther Adv Gastroenterol 6(1):53–68
    Article Google Scholar
  27. Haak BW, Prescott HC, Wiersinga WJ (2018) Therapeutic potential of the gut microbiota in the prevention and treatment of sepsis. Front Immunol 9:2042
    Article Google Scholar
  28. Brennan CA, Garrett WS (2016) Gut microbiota, inflammation, and colorectal cancer. Annu Rev Microbiol 70:395–411
    Article CAS Google Scholar
  29. Kaplan GG, Pedersen BV, Andersson RE, Sands BE, Korzenik J, Frisch M (2007) The risk of developing Crohn’s disease after an appendectomy: a population-based cohort study in Sweden and Denmark. Gut 56(10):1387–1392
    Article Google Scholar
  30. Molodecky NA, Soon IS, Rabi DM et al (2012) Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review. Gastroenterology 142(1):46–54 e42 quiz e30
    Article Google Scholar
  31. Cosnes J, Carbonnel F, Beaugerie L, Blain A, Reijasse D, Gendre JP (2002) Effects of appendicectomy on the course of ulcerative colitis. Gut 51(6):803–807
    Article CAS Google Scholar
  32. Gardenbroek TJ, Pinkney TD, Sahami S, Morton DG, Buskens CJ, Ponsioen CY, Tanis PJ, Löwenberg M, van den Brink GR, Broeders IAMJ, Pullens PHJM, Seerden T, Boom MJ, Mallant-Hent RC, Pierik REGJM, Vecht J, Sosef MN, van Nunen AB, van Wagensveld BA, Stokkers PCF, Gerhards MF, Jansen JM, Acherman Y, Depla ACTM, Mannaerts GHH, West R, Iqbal T, Pathmakanthan S, Howard R, Magill L, Singh B, Htun Oo Y, Negpodiev D, Dijkgraaf MGW, RAM D’Haens G, Bemelman WA (2015) The ACCURE-trial: the effect of appendectomy on the clinical course of ulcerative colitis, a randomised international multicenter trial (NTR2883) and the ACCURE-UK trial: a randomised external pilot trial (ISRCTN56523019). BMC Surg 15:30
    Article Google Scholar
  33. Im GY, Modayil RJ, Lin CT, Geier SJ, Katz DS, Feuerman M, Grendell JH (2011) The appendix may protect against Clostridium difficile recurrence. Clin Gastroenterol Hepatol 9(12):1072–1077
    Article Google Scholar
  34. Chang JY, Antonopoulos DA, Kalra A, Tonelli A, Khalife WT, Schmidt TM, Young VB (2008) Decreased diversity of the fecal microbiome in recurrent Clostridium difficile-associated diarrhea. J Infect Dis 197(3):435–438
    Article Google Scholar
  35. Wu MC, Tsou HK, Lin CL, Wei JC (2020) Incidence and risk of sepsis following appendectomy: a nationwide population-based cohort study. Sci Rep 10(1):10171
    Article CAS Google Scholar
  36. Wu SC, Chen WT, Muo CH, Ke TW, Fang CW, Sung FC (2015) Association between appendectomy and subsequent colorectal cancer development: an Asian population study. PLoS One 10(2):e0118411
    Article Google Scholar
  37. Bendeck SE, Nino-Murcia M, Berry GJ, Jeffrey RB Jr (2002) Imaging for suspected appendicitis: negative appendectomy and perforation rates. Radiology 225(1):131–136
    Article Google Scholar
  38. Kim K, Lee CC, Song KJ, Kim W, Suh G, Singer AJ (2008) The impact of helical computed tomography on the negative appendectomy rate: a multi-center comparison. J Emerg Med 34(1):3–6
    Article Google Scholar
  39. Sugimoto T, Edwards D (1987) Incidence and costs of incidental appendectomy as a preventive measure. Am J Public Health 77(4):471–475
    Article CAS Google Scholar
  40. Lee JH, Park YS, Choi JS (2010) The epidemiology of appendicitis and appendectomy in South Korea: national registry data. J Epidemiol 20(2):97–105
    Article Google Scholar

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