microRNA expression and its potential role in cardioprotection by ischemic postconditioning in pigs (original) (raw)

References

  1. Arad M, Seidman CE, Seidman JG (2007) AMP-activated protein kinase in the heart: role during health and disease. Circ Res 100:474–488. doi:10.1161/01.RES.0000258446.23525.37
    Article PubMed CAS Google Scholar
  2. Bartel DP (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116:281–297. doi:10.1016/j.bbr.2011.03.031
    Article PubMed CAS Google Scholar
  3. Benjamini Y, Hochberg Y (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Statist Soc B 57:289–300. doi:10.1161/hc4001.097183
    Google Scholar
  4. Bonauer A, Carmona G, Iwasaki M, Mione M, Koyanagi M, Fischer A, Burchfield J, Fox H, Doebele C, Ohtani K, Chavakis E, Potente M, Tjwa M, Urbich C, Zeiher AM, Dimmeler S (2009) MicroRNA-92a controls angiogenesis and functional recovery of ischemic tissues in mice. Science 324:1710–1713. doi:10.1126/science.1174381
    Article PubMed CAS Google Scholar
  5. Bostjancic E, Zidar N, Stajer D, Glavac D (2009) MicroRNAs miR-1, miR-133a, miR-133b and miR-208 are dysregulated in human myocardial infarction. Cardiology 115:163–169. doi:10.1159/000268088
    Article PubMed Google Scholar
  6. Chandrasekar B, Freeman GL (1997) Induction of nuclear factor kB and activation protein 1 in postischemic myocardium. FEBS Lett 401:30–34. doi:10.1016/S0014-5793(96)01426-3
    Article PubMed CAS Google Scholar
  7. Dong S, Cheng Y, Yang J, Li J, Liu X, Wang X, Wang D, Krall TJ, Delphin ES, Zhang C (2009) MicroRNA expression signature and the role of microRNA-21 in the early phase of acute myocardial infarction. J Biol Chem 284:29514–29525. doi:10.1074/jbc.M109.027896
    Article PubMed CAS PubMed Central Google Scholar
  8. Fiedler J, Jazbutyte V, Kirchmaier BC, Gupta SK, Lorenzen J, Hartmann D, Galuppo P, Kneitz S, Pena JT, Sohn-Lee C, Loyer X, Soutschek J, Brand T, Tuschl T, Heineke J, Martin U, Schulte-Merker S, Ertl G, Engelhardt S, Bauersachs J, Thum T (2011) MicroRNA-24 regulates vascularity after myocardial infarction. Circulation 124:720–730. doi:10.1161/CIRCULATIONAHA.111.039008
    Article PubMed CAS Google Scholar
  9. Fleige S, Pfaffl MW (2006) RNA integrity and the effect on the real-time qRT-PCR performance. Mol Aspects Med 27:126–139. doi:10.1016/j.mam.2005.12.003
    Article PubMed CAS Google Scholar
  10. He B, Xiao J, Ren AJ, Zhang YF, Zhang H, Chen M, Xie B, Gao XG, Wang YW (2011) Role of miR-1 and miR-133a in myocardial ischemic postconditioning. J Biomed Sci 18:22. doi:10.1186/1423-0127-18-22
    Article PubMed CAS PubMed Central Google Scholar
  11. Heusch G (2004) Postconditioning. Old wine in a new bottle? J Am Coll Cardiol 44:1111–1112. doi:10.1016/j.jacc.2004.06.013
    Article PubMed Google Scholar
  12. Heusch G (2013) Cardioprotection—chances and challenges of its translation to the clinic. Lancet 381:166–175. doi:10.1016/S0140-6736(12)60916-7
    Article PubMed Google Scholar
  13. Heusch G, Musiolik J, Gedik N, Skyschally A (2011) Mitochondrial STAT3 activation and cardioprotection by ischemic postconditioning in pigs with regional myocardial ischemia/reperfusion. Circ Res 109:1302–1308. doi:10.1161/CIRCRESAHA.111.255604
    Article PubMed CAS Google Scholar
  14. Heusch G, Schulz R (2009) Neglect of the coronary circulation: some critical remarks on problems in the translation of cardioprotection. Cardiovasc Res 84:11–14. doi:10.1093/cvr/cvp210
    Article PubMed CAS Google Scholar
  15. Heusch G, Skyschally A, Schulz R (2011) The in-situ pig heart with regional ischemia/reperfusion—ready for translation. J Mol Cell Cardiol 50:951–963. doi:10.1016/j.yjmcc.2011.02.016
    Article PubMed CAS Google Scholar
  16. Hinkel R, Penzkofer D, Zuhlke S, Fischer A, Husada W, Xu QF, Baloch E, van Rooij E, Zeiher AM, Kupatt C, Dimmeler S (2013) Inhibition of microRNA-92a protects against ischemia-reperfusion injury in a large animal model. Circulation 128:1066–1075. doi:10.1161/CIRCULATIONAHA.113.00190
    Article PubMed CAS Google Scholar
  17. Kowallik P, Schulz R, Guth BD, Schade A, Paffhausen W, Gross R, Heusch G (1991) Measurement of regional myocardial blood flow with multiple colored microspheres. Circulation 83:974–982. doi:10.1161/01.CIR.83.3974
    Article PubMed CAS Google Scholar
  18. Kukreja RC, Yin C, Salloum FN (2011) MicroRNAs: new players in cardiac injury and protection. Mol Pharmacol 80:558–564. doi:10.1124/mol.111.073528
    Article PubMed CAS PubMed Central Google Scholar
  19. Lassen JF, Botker HE, Terkelsen CJ (2012) Timely and optimal treatment of patients with STEMI. Nat Rev Cardiol 10:41–48. doi:10.1038/nrcardio.2012.156
    Article PubMed Google Scholar
  20. Li C, Browder W, Kao RL (1999) Early activation of transcription factor NF-kappaB during ischemia in perfused rat heart. Am J Physiol 276:H543–H552
    PubMed CAS Google Scholar
  21. Li G, Labruto F, Sirsjo A, Chen F, Vaage J, Valen G (2004) Myocardial protection by remote preconditioning: the role of nuclear factor kappa-B p105 and inducible nitric oxide synthase. Eur J Cardiothorac Surg 26:968–973. doi:10.1016/j.ejcts.2004.06.015
    Article PubMed Google Scholar
  22. Li J, Coven DL, Miller EJ, Hu X, Young ME, Carling D, Sinusas AJ, Young LH (2006) Activation of AMPK alpha- and gamma-isoform complexes in the intact ischemic rat heart. Am J Physiol Heart Circ Physiol 291:H1927–H1934. doi:10.1152/ajpheart.00251.2006
    Article PubMed CAS Google Scholar
  23. Martinez-Gonzalez J, Rius J, Castello A, Cases-Langhoff C, Badimon L (2003) Neuron-derived orphan receptor-1 (NOR-1) modulates vascular smooth muscle cell proliferation. Circ Res 92:96–103. doi:10.1161/01.RES.0000050921.53008.47
    Article PubMed CAS Google Scholar
  24. Matthews JM, Lester K, Joseph S, Curtis DJ (2013) LIM-domain-only proteins in cancer. Nat Rev Cancer 13:111–122. doi:10.1038/nrc3418
    Article PubMed CAS Google Scholar
  25. Morgan EN, Boyle EM Jr, Yun W, Griscavage-Ennis JM, Farr AL, Canty TG Jr, Pohlman TH, Verrier ED (1999) An essential role of NF-kappaB in the cardioadaptive response to ischemia. Ann Thorac Surg 68:377–382. doi:10.1016/S0003-4975(99)00646-3
    Article PubMed CAS Google Scholar
  26. Musi N, Hirshman MF, Arad M, Xing Y, Fujii N, Pomerleau J, Ahmad F, Berul CI, Seidman JG, Tian R, Goodyear LJ (2005) Functional role of AMP-activated protein kinase in the heart during exercise. FEBS Lett 579:2045–2050. doi:10.1016/j.febslet.2005.02.052
    Article PubMed CAS Google Scholar
  27. Ohtani K, Dimmeler S (2011) Control of cardiovascular differentiation by microRNAs. Basic Res Cardiol 106:5–11. doi:10.1007/s00395-010-0139-7
    Article PubMed CAS Google Scholar
  28. Ovize M, Baxter GF, Di Lisa F, Ferdinandy P, Garcia-Dorado D, Hausenloy DJ, Heusch G, Vinten-Johansen J, Yellon DM, Schulz R (2010) Postconditioning and protection from reperfusion injury: where do we stand? Cardiovasc Res 87:406–423. doi:10.1093/cvr/cvq129
    Article PubMed CAS Google Scholar
  29. Park SY, Lee JH, Ha M, Nam JW, Kim VN (2009) miR-29 miRNAs activate p53 by targeting p85 alpha and CDC42. Nat Struct Mol Biol 16:23–29. doi:10.1038/nsmb.1533
    Article PubMed CAS Google Scholar
  30. Roy S, Khanna S, Hussain SR, Biswas S, Azad A, Rink C, Gnyawali S, Shilo S, Nuovo GJ, Sen CK (2009) MicroRNA expression in response to murine myocardial infarction: miR-21 regulates fibroblast metalloprotease-2 via phosphatase and tensin homologue. Cardiovasc Res 82:21–29. doi:10.1093/cvr/cvp015
    Article PubMed CAS PubMed Central Google Scholar
  31. Rozen S, Skaletsky H (2000) Primer3 on the WWW for general users and for biologist programmers. Methods Mol Biol 132:365–386
    PubMed CAS Google Scholar
  32. Russell RR III, Li J, Coven DL, Pypaert M, Zechner C, Palmeri M, Giordano FJ, Mu J, Birnbaum MJ, Young LH (2004) AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury. J Clin Invest 114:495–503. doi:10.1172/JCI21233
    Article PubMed CAS PubMed Central Google Scholar
  33. Shan ZX, Lin QX, Fu YH, Deng CY, Zhou ZL, Zhu JN, Liu XY, Zhang YY, Li Y, Lin SG, Yu XY (2009) Upregulated expression of miR-1/miR-206 in a rat model of myocardial infarction. Biochem Biophys Res Commun 381:597–601. doi:10.1016/j.bbrc.2009.02.097
    Article PubMed CAS Google Scholar
  34. Siegrist F, Ebeling M, Certa U (2011) The small interferon-induced transmembrane genes and proteins. J Interferon Cytokine Res 31:183–197. doi:10.1089/jir.2010.0112
    Article PubMed CAS Google Scholar
  35. Skyschally A, van Caster P, Boengler K, Gres P, Musiolik J, Schilawa D, Schulz R, Heusch G (2009) Ischemic postconditioning in pigs: no causal role for RISK activation. Circ Res 104:15–18. doi:10.1161/CIRCRESAHA.108.186429
    Article PubMed CAS Google Scholar
  36. Skyschally A, van Caster P, Iliodromitis EK, Schulz R, Kremastinos DT, Heusch G (2009) Ischemic postconditioning—experimental models and protocol algorithms. Basic Res Cardiol 104:469–483. doi:10.1007/s00395-009-0040-4
    Article PubMed Google Scholar
  37. Staat P, Rioufol G, Piot C, Cottin Y, Cung TT, L’Huillier I, Aupetit J-F, Bonnefoy E, Finet G, Andre-Fouet X, Ovize M (2005) Postconditioning the human heart. Circulation 112:2143–2148. doi:10.1161/CIRCULATIONAHA.105.558122
    Article PubMed Google Scholar
  38. Tian R, Musi N, D’Agostino J, Hirshman MF, Goodyear LJ (2001) Increased adenosine monophosphate-activated protein kinase activity in rat hearts with pressure-overload hypertrophy. Circulation 104:1664–1669. doi:10.1161/hc4001.097183
    Article PubMed CAS Google Scholar
  39. Valen G (2009) Extracardiac approaches to protecting the heart. Eur J Cardiothorac Surg 35:651–657. doi:10.1016/j.ejcts.2008.12.023
    Article PubMed Google Scholar
  40. van Rooij E, Sutherland LB, Thatcher JE, DiMaio JM, Naseem RH, Marshall WS, Hill JA, Olson EN (2008) Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis. Proc Natl Acad Sci U S A 105:13027–13032. doi:10.1073/pnas.0805038105
    Article PubMed PubMed Central Google Scholar
  41. Wang JX, Jiao JQ, Li Q, Long B, Wang K, Liu JP, Li YR, Li PF (2011) miR-499 regulates mitochondrial dynamics by targeting calcineurin and dynamin-related protein-1. Nat Med 17:71–78. doi:10.1038/nm.2282
    Article PubMed Google Scholar
  42. Weiss JB, Eisenhardt SU, Stark GB, Bode C, Moser M, Grundmann S (2012) MicroRNAs in ischemia-reperfusion injury. Am J Cardiovasc Dis 2:237–247
    PubMed CAS PubMed Central Google Scholar
  43. Welman E, Colbeck JF, Selwyn AP, Fox KM, Orr I (1980) Plasma lysosomal enzyme activity in acute myocardial infarction and the effects of drugs. Adv Myocardiol 2:359–369
    PubMed CAS Google Scholar
  44. Welman E, Selwyn AP, Peters TJ, Colbeck JF, Fox KM (1978) Plasma lysosomal enzyme activity in acute myocardial infarction. Cardiovasc Res 12:99–105
    Article PubMed CAS Google Scholar
  45. Xu C, Lu Y, Pan Z, Chu W, Luo X, Lin H, Xiao J, Shan H, Wang Z, Yang B (2007) The muscle-specific microRNAs miR-1 and miR-133 produce opposing effects on apoptosis by targeting HSP60, HSP70 and caspase-9 in cardiomyocytes. J Cell Sci 120:3045–3052. doi:10.1242/jcs.098830
    Article PubMed CAS Google Scholar
  46. Ye Y, Hu Z, Lin Y, Zhang C, Perez-Polo JR (2010) Downregulation of microRNA-29 by antisense inhibitors and a PPAR-g agonist protects against myocardial ischaemia-reperfusion injury. Cardiovasc Res 87:535–544. doi:10.1093/cvr/cvq053
    Article PubMed CAS Google Scholar
  47. Yellon DM, Hausenloy DJ (2007) Myocardial reperfusion injury. N Engl J Med 357:1121–1135. doi:10.1093/cvr/cvq053
    Article PubMed CAS Google Scholar
  48. Zhao Z-Q, Corvera JS, Halkos ME, Kerendi F, Wang N-P, Guyton RA, Vinten-Johansen J (2003) Inhibition of myocardial injury by ischemic postconditioning during reperfusion: comparison with ischemic preconditioning. Am J Physiol Heart Circ Physiol 285:H579–H588. doi:10.1152/ajpheart.01064.2002
    PubMed CAS Google Scholar

Download references