Nucleotide and haplotypic diversity of the NOS2A promoter region and its relationship to cerebral malaria (original) (raw)
References
Al-Yaman FM, Mokela D, Genton B., Rockett KA, Alpers MP, Clark IA (1996) Association between serum levels of reactive nitrogen intermediates and coma in children with cerebral malaria in Papua New Guinea. Trans R Soc Trop Med Hyg 90:270–273 CASPubMed Google Scholar
Anstey NM, Weinberg JB, Hassanali MY, Mwaikambo ED, Manyenga D, Misukonis MA, Arnelle DR, Hollis D, McDonald MI, Granger DL (1996) Nitric oxide in Tanzanian children with malaria: inverse relationship between malaria severity and nitric oxide production/nitric oxide synthase type 2 expression. J Exp Med 184:557–567 CASPubMed Google Scholar
Burgner D, Xu W, Rockett K, Gravenor M, Charles IG, Hill AV, Kwiatkowski D (1998) Inducible nitric oxide synthase polymorphism and fatal cerebral malaria. Lancet 352:1193–1194 ArticleCASPubMed Google Scholar
Cargill M, Altshuler D, Ireland J, Sklar P, Ardlie K, Patil N, Lane CR, Lim EP, Kalayanaraman N, Nemesh J, Ziaugra L, Friedland L, Rolfe A, Warrington J, Lipshutz R, Daley GQ, Lander ES (1999) Characterization of single-nucleotide polymorphisms in coding regions of human genes. Nat Genet 22:231–238 PubMed Google Scholar
Clark AG, Weiss KM, Nickerson DA, Taylor SL, Buchanan A, Stengard J, Salomaa V, Vartiainen E, Perola M, Boerwinkle E, Sing CF (1998) Haplotype structure and population genetic inferences from nucleotide-sequence variation in human lipoprotein lipase. Am J Hum Genet 63:595–612 CASPubMed Google Scholar
Clark IA, Rockett KA (1996) Nitric oxide and parasitic disease. Adv Parasitol 37:1–56 CASPubMed Google Scholar
Clark IA, Rockett KA, Cowden WB (1992) Possible central role of nitric oxide in conditions clinically similar to cerebral malaria. Lancet 340:894–896 CASPubMed Google Scholar
Clark IA, Awburn MM, Whitten RO, Carr RA, Liomba NG, Molyneux ME, Taylor TE (1999) Immunohistochemical evidence for iNOS and nitrotyrosine production in fatal falciparum malaria in African children. Acta Physiol Scand 167 (Suppl 645):14 Google Scholar
Clayton D (1999) A generalization of the transmission/disequilibrium test for uncertain haplotype transmission. Am J Hum Genet 65:1170–1177 PubMed Google Scholar
Daly MJ, Rioux JD, Schaffner SF, Hudson TJ, Lander ES (2001) High-resolution haplotype structure in the human genome. Nat Genet 29:229–232 CASPubMed Google Scholar
Gavrilyuk V, Horvath P, Weinberg G, Feinstein DL (2001) A 27-bp region of the inducible nitric oxide synthase promoter regulates expression in glial cells. J Neurochem 78:129–140 ArticleCASPubMed Google Scholar
Granger DL, Anstey NM, Miller WC, Weinberg JB (1999) Measuring nitric oxide production in human clinical studies. Methods Enzymol 301:49–61 CASPubMed Google Scholar
Hensbroek MB van, Palmer A, Jaffar S, Schneider G, Kwiatkowski D (1997) Residual neurologic sequelae after childhood cerebral malaria. J Pediatr 131:125–129 PubMed Google Scholar
Hill AV, Allsopp CE, Kwiatkowski D, Anstey NM, Twumasi P, Rowe PA, Bennett S, Brewster D, McMichael AJ, Greenwood BM (1991) Common west African HLA antigens are associated with protection from severe malaria. Nature 352:595–600 CASPubMed Google Scholar
Hoffman SL, Franke ED, Hollingdale MR, Druilhe P (1996) Attacking the infected hepatocyte. In: Hoffman SL (ed) Malaria vaccine development: a multi-immune response approach. American Society for Microbiology, Washington DC, pp 2005–2006 Google Scholar
Hull J, Ackerman H, Isles K, Usen S, Pinder M, Thomson A, Kwiatkowski D (2001) Unusual haplotypic structure of IL8, a susceptibility locus for a common respiratory virus. Am J Hum Genet 69:413–419 ArticleCASPubMed Google Scholar
Ikuta S, Takagi K, Wallace RB, Itakura K (1987) Dissociation kinetics of 19 base paired oligonucleotide-DNA duplexes containing different single mismatched base pairs. Nucleic Acids Res 15:797–811 CASPubMed Google Scholar
Johnson GC, Esposito L, Barratt BJ, Smith AN, Heward J, Di Genova G, Ueda H, Cordell HJ, Eaves IA, Dudbridge F, Twells RC, Payne F, Hughes W, Nutland S, Stevens H, Carr P, Tuomilehto-Wolf E, Tuomilehto J, Gough SC, Clayton DG, Todd JA (2001) Haplotype tagging for the identification of common disease genes. Nat Genet 29:233–237 CASPubMed Google Scholar
Kremsner PG, Winkler S, Wildling E, Prada J, Bienzle U, Graninger W, Nussler AK (1996) High plasma levels of nitrogen oxides are associated with severe disease and correlate with rapid parasitological and clinical cure in Plasmodium falciparum malaria. Trans R Soc Trop Med Hyg 90:44–47 CASPubMed Google Scholar
Kruglyak L (1999) Prospects for whole-genome linkage disequilibrium mapping of common disease genes. Nat Genet 22:139–144 ArticlePubMed Google Scholar
Kun JF, Mordmuller B, Lell B, Lehman LG, Luckner D, Kremsner PG (1998) Polymorphism in promoter region of inducible nitric oxide synthase gene and protection against malaria. Lancet 351:265–266 CASPubMed Google Scholar
Kun JF, Klabunde J, Lell B, Luckner D, Alpers M, May J, Meyer C, Kremsner PG (1999) Association of the ICAM-1Kilifi mutation with protection against severe malaria in Lambarene, Gabon. Am J Trop Med Hyg 61:776–779 CASPubMed Google Scholar
Kun JF, Mordmuller B, Perkins DJ, May J, Mercereau-Puijalon O, Alpers M, Weinberg JB, Kremsner PG (2001) Nitric oxide synthase 2(Lambarene) (G-954C), increased nitric oxide production, and protection against malaria. J Infect Dis 184:330–336 ArticleCASPubMed Google Scholar
Levesque MC, Hobbs MR, Anstey NM, Vaughn TN, Chancellor JA, Pole A, Perkins DJ, Misukonis MA, Chanock SJ, Granger DL, Weinberg JB (1999) Nitric oxide synthase type 2 promoter polymorphisms, nitric oxide production, and disease severity in Tanzanian children with Malaria. J Infect Dis 180:1994–2002 ArticleCASPubMed Google Scholar
Linn SC, Morelli PJ, Edry I, Cottongim SE, Szabo C, Salzman AL (1997) Transcriptional regulation of human inducible nitric oxide synthase gene in an intestinal epithelial cell line. Am J Physiol 272:G1499–G1508 CASPubMed Google Scholar
Marks-Konczalik J, Chu SC, Moss J (1998) Cytokine-mediated transcriptional induction of the human inducible nitric oxide synthase gene requires both activator protein 1 and nuclear factor kappaB-binding sites. J Biol Chem 273:22201–22208 CASPubMed Google Scholar
Molyneux M, Taylor T, Wirima J, Borgstein A (1989) Clinical features and prognostic indicators in paediatric cerebral malaria: a study of 131 comatose Malawian children. Q J Med 71:441–459 CASPubMed Google Scholar
Morris BJ, Markus A, Glenn CL, Adams DJ, Colagiuri S, Wang L (2002) Association of a functional inducible nitric oxide synthase promoter variant with complications in type 2 diabetes. J Mol Med 80:96–104 ArticleCASPubMed Google Scholar
Nathan C (1997) Inducible nitric oxide synthase: what difference does it make? J Clin Invest 100:2417–2423 Google Scholar
Pance A, Chantome A, Reveneau S, Bentrari F, Jeannin JF (2002) A repressor in the proximal human inducible nitric oxide synthase promoter modulates transcriptional activation. FASEB J 16:631–633 CASPubMed Google Scholar
Povey S, Lovering R, Bruford E, Wright M, Lush M, Wain H (2001) The HUGO Gene Nomenclature Committee (HGNC). Hum Genet 109:678–680 CASPubMed Google Scholar
Rockett KA, Awburn MM, Cowden WB, Clark IA (1991) Killing of Plasmodium falciparum in vitro by nitric oxide derivatives. Infect Immun 59:3280–3283 CASPubMed Google Scholar
Rockett KA, Brookes R, Udalova I, Vidal V, Hill AV, Kwiatkowski D (1998) 1,25-Dihydroxyvitamin D3 induces nitric oxide synthase and suppresses growth of Mycobacterium tuberculosis in a human macrophage-like cell line. Infect Immun 66:5314–5321 CASPubMed Google Scholar
Schaid DJ (1996) General score tests for associations of genetic markers with disease using cases and their parents. Genet Epidemiol 13:423–449 ArticleCASPubMed Google Scholar
Schoedon G, Schneemann M, Walter R, Blau N, Hofer S, Schaffner A (1995) Nitric oxide and infection: another view. Clin Infect Dis 21 (Suppl 2):S152–S157 CASPubMed Google Scholar
Spielman RS, McGinnis RE, Ewens WJ (1993) Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am J Hum Genet 52:506–516 PubMed Google Scholar
Spitsin SV, Koprowski H, Michaels FH (1996) Characterization and functional analysis of the human inducible nitric oxide synthase gene promoter. Mol Med 2:226–235 CASPubMed Google Scholar
Udalova IA, Richardson A, Denys A, Smith C, Ackerman H, Foxwell B, Kwiatkowski D (2000) Functional consequences of a polymorphism affecting NF-kappaB p50-p50 binding to the TNF promoter region. Mol Cell Biol 20:9113–9119 ArticleCASPubMed Google Scholar
Vera ME de, Shapiro RA, Nussler AK, Mudgett JS, Simmons RL, Morris SM Jr, Billiar TR, Geller DA (1996) Transcriptional regulation of human inducible nitric oxide synthase (NOS2) gene by cytokines: initial analysis of the human NOS2 promoter. Proc Natl Acad Sci USA 93:1054–1059 ArticlePubMed Google Scholar
Wallace RB, Shaffer J, Murphy RF, Bonner J, Hirose T, Itakura K (1979) Hybridization of synthetic oligodeoxyribonucleotides to phi chi 174 DNA: the effect of single base pair mismatch. Nucleic Acids Res 6:3543–3557 CASPubMed Google Scholar
Wingender E, Chen X, Hehl R, Karas H, Liebich I, Matys V, Meinhardt T, Pruss M, Reuter I, Schacherer F (2000) TRANSFAC: an integrated system for gene expression regulation. Nucleic Acids Res 28:316–319 CASPubMed Google Scholar
Xu W, Liu L, Emson PC, Harrington CR, Charles IG (1997) Evolution of a homopurine-homopyrimidine pentanucleotide repeat sequence upstream of the human inducible nitric oxide synthase gene. Gene 204:165–170 CASPubMed Google Scholar