Recent changes in bacteremia in patients with cancer: a systematic review of epidemiology and antibiotic resistance (original) (raw)

References

  1. Klastersky J (2004) Management of fever in neutropenic patients with different risks of complications. Clin Infect Dis 39:S327
    Article Google Scholar
  2. Freifeld AG, Bow EJ, Sepkowitz KA, Boeckh MJ, Ito JI, Mullen CA, Raad II, Rolston KV, Young JA, Wingard JR, Infectious Diseases Society of America (2011) Clinical practice guideline for the use of antimicrobial agents in neutropenic patients with cancer: 2010 Update by the Infectious Diseases Society of America. Clin Infect Dis 52(4):427–431
    Article PubMed Google Scholar
  3. Arnold RJ, Gabrail N, Rat M, Kim R, Sung JC, Zhou Y (2005) Clinical implications of chemotherapy induced diarrhea in patients with cancer. J Support Oncol 3:227–232
    PubMed Google Scholar
  4. van Vliet MJ, Harmsen HJ, de Bont ES, Tissing WJ (2010) The role of intestinal microbiota in the development and severity of chemotherapy-induced Mucositis. Plos Pathol 27:e1000879
    Article Google Scholar
  5. Jones RN (1999) Contemporary antimicrobial susceptibility pattern of bacterial pathogens commonly associated with febrile patients with neutropenia. Clin Infect Dis 29:495–502
    Article CAS PubMed Google Scholar
  6. Irfan S, Idrees F, Mehraj V, Habib F, Adil S, Hasan R (2008) Emergence of Carbapenem resistant Gram negative and vancomycin resistant Gram positive organisms in bacteremic isolates of febrile neutropenic patients: a descriptive study. BMC Infect Dis 8:80
    Article PubMed Google Scholar
  7. Ramphal R (2004) Changes in the etiology of bacteremia in febrile neutropenic patients and the susceptibilities of the currently isolated pathogens. Clin Infect Dis 39:S25–S31
    Article PubMed Google Scholar
  8. Zinner SH (1999) Changing epidemiology of infections in patients with neutropenia and cancer: emphasis on gram-positive and resistant bacteria. Clin Infect Dis 29:490–494
    Article CAS PubMed Google Scholar
  9. Wisplinghoff H, Seifert H, Wenzel RP, Edmond MB (2003) Current trends in the epidemiology of nosocomial bloodstream infections in patients with hematological malignancies and solid neoplasms in hospitals in the United States. Clin Infect Dis 36:1103–1110
    Article PubMed Google Scholar
  10. Sharma A, Lokeshwar N (2005) Febrile neutropenia in haematological malignancies. J Postgrad Med 51:42–48
    Google Scholar
  11. Wu HS, Kuo SC, Lee YT, Yang YS, Cheng SS, Chen TL, Fung CP (2012) Clinical characteristics and prognostic factors of Acinetobacter nosocomialis bacteraemia in patients with solid tumours. Clin Microbiol Infect 18(9):E373–E376
    Article PubMed Google Scholar
  12. Kang CI, Kim SH, Park WB, Lee KD, Kim HB, Kim EC, Oh MD, Choe KW (2004) Bloodstream infections due to extended spectrum factors for mortality and treatment outcome, with special emphasis on antimicrobial therapy. Antimicrob Agents Chemother 48:4574–4581
    Article CAS PubMed Google Scholar
  13. Kim YK, Pai H, Lee HJ, Park SE, Choi EH, Kim J, Kim JH, Kim EC (2002) Bloodstream infections by extended-spectrum β-lactamase producing Escherichia coli and Klebsiella pneumoniae in children: epidemiology and clinical outcome. Antimicrob Agents Chemother 46(1481):1491
    Google Scholar
  14. Cattaneo C, Antoniazzi F, Casari S, Ravizzola G, Gelmi M, Pagani C, D’Adda M, Morello E, Re A, Borlenghi E, Manca N, Rossi G (2012) P. aeruginosa bloodstream infections among hematological patients: an old or new question? Ann Hematol 91(8):1299–1304
    Article PubMed Google Scholar
  15. Kjellander C, Björkholm M, Cherif H, Kalin M, Giske CG (2012) Hematological: low all-cause mortality and low occurrence of antimicrobial resistance in hematological patients with bacteremia receiving no antibacterial prophylaxis: a single-center study. Eur J Haematol 88(5):422–430
    Article CAS PubMed Google Scholar
  16. Chong Y, Yakushiji H, Ito Y, Kamimura T (2011) Clinical impact of fluoroquinolone prophylaxis in neutropenic patients with hematological malignancies. Int J Infect Dis 15(4):e277–e281
    Article CAS PubMed Google Scholar
  17. Saghir S, Faiz M, Saleem M, Younus A, Aziz H (2009) Characterization and anti-microbial susceptibility of Gram-negative bacteria isolated from bloodstream infections of cancer patients on chemotherapy in Pakistan. Indian J Med 27:341–347
    CAS Google Scholar
  18. Kang CI, Song JH, Chung DR, Peck KR, Yeom JS, Son JS, Wi YM, on behalf of the Korean Network for Study on Infectious Diseases (KONSID) (2012) Bloodstream infections in adult patients with cancer: clinical features and pathogenic significance of Staphylococcus aureus bacteremia. Support Care Cancer 20(10):2371–2378
    Google Scholar
  19. Lanoix JP, Pluquet E, Lescure FX, Bentayeb H, Lecuyer E, Boutemy M, Dumont P, Jounieaux V, Schmit JL, Dayen C, Douadi Y (2011) Bacterial infection profiles in lung cancer patients with febrile neutropenia. BMC Infect Dis 11:183
    Article PubMed Google Scholar
  20. Gudiol C, Bodro M, Simonetti A, Tubau F, González-Barca E, Cisnal M, Domingo-Domenech E, Jiménez L, Carratalà J (2012) Changing aetiology, clinical features, antimicrobial resistance, and outcomes of bloodstream infection in neutropenic cancer patients. Clin Microbiol Infect. doi:10.1111/j.1469-0691.2012.03879
  21. Trecarichi EM, Tumbarello M, Spanu T, Caira M, Fianchi L, Chiusolo P, Fadda G, Leone G, Cauda R, Pagano L (2009) Incidence and clinical impact of extended-spectrum-beta-lactamase (ESBL) production and fluoroquinolone resistance in bloodstream infections caused by Escherichia coli in patients with hematological malignancies. J Infect 58(4):299–307
    Article PubMed Google Scholar
  22. Bhusal Y, Mihu CN, Tarrand JJ, Rolston KV (2011) Incidence of fluoroquinolone-resistant and extended-spectrum β-lactamase-producing Escherichia coli at a comprehensive cancer center in the United States. Chemotherapy 57(4):335–338
    Article CAS PubMed Google Scholar
  23. Jacobson K, Rolston K, Elting L, LeBlanc B, Whimbey E, Ho DH (1999) Susceptibility surveillance among Gram-negative bacilli at a cancer center. Chemotherapy 45:325–334
    Article CAS PubMed Google Scholar
  24. Mihu CN, Rhomberg PR, Jones RN, Coyle E, Prince RA, Rolston KV (2010) Escherichia coli resistance to quinolones at a comprehensive cancer center. Diagn Microbiol Infect Dis 67(3):266–269
    Article CAS PubMed Google Scholar
  25. Bell JM, Turnidge JD, Gales AC, Pfaller MA, Jones RN, Sentry APAC Study Group (2002) Prevalence of extended-spectrum beta-lactamase (ESBL)—producing clinical isolates in the Asia-Pacific region and South Africa: regional results from SENTRY Antimicrobial Surveillance Program (1998–99). Diagn Microbiol Infect Dis 42:193–198
    Article PubMed Google Scholar
  26. Gulay Z, Thomson CJ, Yulug N, Amyes SG (2000) High prevalence of extended spectrum beta-lactamase production among Klebsiella pneumoniae strains isolated at a university hospital in Turkey. J Chemother 12:145–152
    CAS PubMed Google Scholar
  27. Vahaboglu H, Ozturk R, Aygun G, Coşkunkan F, Yaman A, Kaygusuz A, Leblebicioglu H, Balik I, Aydin K, Otkun M (1997) Widespread detection of PER-1–type extended-spectrum beta-lactamases among nosocomial Acinetobacter and Pseudomonas aeruginosa isolates in Turkey: a nationwide multicenter study. Antimicrob Agents Chemother 41:2265–2269
    CAS PubMed Google Scholar
  28. Arnan M, Gudiol C, Calatayud L, Liñares J, Dominguez MA, Batlle M, Ribera JM, Carratalà J, Gudiol F (2011) Risk factors for, and clinical relevance of, faecal extended-spectrum β-lactamase producing Escherichia coli (ESBL-EC) carriage in neutropenic patients with haematological malignancies. Eur J Clin Microbiol Infect Dis 30(3):355–360
    Article CAS PubMed Google Scholar
  29. Gudiol C, Calatayud L, Garcia-Vidal C, Lora-Tamayo J, Cisnal M, Duarte R, Arnan M, Marin M, Carratalà J, Gudiol F (2010) Bacteraemia due to extended-spectrum beta-lactamase-producing Escherichia coli (ESBL-EC) in cancer patients: clinical features, risk factors, molecular epidemiology and outcome. J Antimicrob Chemother 65(2):333–341
    Article CAS PubMed Google Scholar
  30. Liss BJ, Vehreschild JJ, Cornely OA, Hallek M, Fätkenheuer G, Wisplinghoff H, Seifert H, Vehreschild MJ (2012) Intestinal colonisation and blood stream infections due to vancomycin-resistant enterococci (VRE) and extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBLE) in patients with haematological and oncological malignancies. Infection 40(6):613–619
    Article CAS PubMed Google Scholar
  31. Kang CI, Chung DR, Ko KS, Peck KR, Song JH, Korean Network for Study of Infectious Diseases (2012) Risk factors for infection and treatment outcome of extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae bacteremia in patients with hematologic malignancy. Ann Hematol 91(1):115–121
    Article CAS PubMed Google Scholar
  32. Almyroudis NG, Fuller A, Jakubowski A, Sepkowitz K, Jaffe D, Small TN, Kiehn TE, Pamer E, Papanicolaou GA (2005) Pre- and postengraftment bloodstream infection rates and associated mortality in allogeneic hematopoietic stem cell transplant recipients. Transpl Infect Dis 7:11–17
    Article CAS PubMed Google Scholar
  33. Avery R, Kalaycio M, Pohlman B, Sobecks R, Kuczkowski E, Andresen S, Mossad S, Shamp J, Curtis J, Kosar J, Sands K, Serafin M, Bolwell B (2005) Early vancomycin resistant enterococcus (VRE) bacteremia after allogeneic bone marrow transplantation is associated with a rapidly deteriorating clinical course. Bone Marrow Transplant 35:497–499
    Article CAS PubMed Google Scholar
  34. Kapur D, Dorsky D, Feingold JM, Bona RD, Edwards RL, Aslanzadeh J, Tutschka PJ, Bilgrami S (2000) Incidence and outcome of vancomycin-resistant enterococcal bacteremia following autologous peripheral blood stem cell transplantation. Bone Marrow Transplant 25:147–152
    Article CAS PubMed Google Scholar
  35. Weinstock DM, Conlon M, Iovino C, Aubrey T, Gudiol C, Riedel E, Young JW, Kiehn TE, Zuccotti G (2007) Colonization, bloodstream infection, and mortality caused by vancomycin-resistant enterococcus early after allogeneic hematopoietic stem cell transplant. Biol Blood Marrow Transplant 13:615–621
    Article PubMed Google Scholar
  36. Zirakzadeh A, Gastineau DA, Mandrekar JN, Burke JP, Johnston BP, Patel R (2008) Vancomycin-resistant enterococcal colonization appears associated with increased mortality among allogeneic hematopoietic stem cell transplant recipients. Bone Marrow Transplant 41:385–392
    Article CAS PubMed Google Scholar
  37. Kamboj M, Chung D, Seo SK, Pamer EG, Sepkowitz KA, Jakubowski AA, Papanicolaou G (2010) The changing epidemiology of vancomycin-resistant Enterococcus (VRE) bacteremia in allogeneic hematopoietic stem cell transplant (HSCT) recipients. Biol Blood Marrow Transplant 16(11):1576–1581
    Article PubMed Google Scholar
  38. Bossaer JB, Hall PD, Garrett-Mayer E (2010) Incidence of vancomycin-resistant enterococci (VRE) infection in high-risk febrile neutropenic patients colonized with VRE. Support Care Cancer 19(2):231–237
    Article PubMed Google Scholar
  39. Quilty S, Kwok G, Hajkowicz K, Currie B (2009) High incidence of methicillin resistant Staphylococcus aureus sepsis and death in patients with febrile neutropenia at Royal Darwin Hospital. Intern Med J 39:557–559
    Article CAS PubMed Google Scholar
  40. Prabhash K, Medhekar A, Ghadyalpatil N, Noronha V, Biswas S, Kurkure P, Nair R, Kelkar R (2010) Blood stream infections in cancer patients: a single center experience of isolates and sensitivity pattern. Indian J Cancer 47:184–188
    Article CAS PubMed Google Scholar
  41. Karim M, Khan W, Farooqi B, Malik I (1991) Bacterial isolates in neutropenic febrile patients. J Pak Med Assoc 48:364–367
    Google Scholar
  42. Rangaraj G, Granwehr BP, Jiang Y, Hachem R, Raad I (2010) Perils of quinolone exposure in cancer patients: breakthrough bacteremia with multidrug-resistant organisms. Cancer 116(4):967–973
    Article PubMed Google Scholar
  43. Gudiol C, Tubau F, Calatayud L, Garcia-Vidal C, Cisnal M, Sánchez-Ortega I, Duarte R, Calvo M, Carratalà J (2011) Bacteraemia due to multidrug-resistant Gram-negative bacilli in cancer patients: risk factors, antibiotic therapy and outcomes. J Antimicrob Chemother 66(3):657–663
    Article CAS PubMed Google Scholar
  44. Trecarichi EM, Tumbarello M, Caira M, Candoni A, Cattaneo C, Pastore D, Fanci R, Nosari A, Vianelli N, Busca A, Spadea A, Pagano L (2011) Multidrug resistant Pseudomonas aeruginosa bloodstream infection in adult patients with hematologic malignancies. Haematologica 96(1):e1–e3
    Article PubMed Google Scholar
  45. Klastersky J, Ameye L, Maertens J, Georgala A, Muanza F, Aoun M, Ferrant A, Rapoport B, Rolston K, Paesmans M (2007) Bacteraemia in febrile neutropenic cancer patients. Int J Antimicrob Agents S1:S51–S59
    Article Google Scholar
  46. Cruciani M, Rampazzo R, Malena M, Lazzarini L, Todeschini G, Messori A, Concia E (1996) Prophylaxis with fluoroquinolones for bacterial infections in neutropenic patients: a meta-analysis. Clin Infect Dis 23:795–805
    Article CAS PubMed Google Scholar
  47. Bow EJ (2011) Fluoroquinolones, antimicrobial resistance and neutropenic cancer patients. Curr Opin Infect Dis 24(6):545–553
    Article CAS PubMed Google Scholar
  48. CLSI (2008) Performance standards for antimicrobial susceptibility testing; eighteenth informational supplement. CLSI document M100-S18. Enterobacteriaceae M7MIC. Clinical and Laboratory Standards Institute, Wayne, PA, pp 98–101
  49. Saito T, Yoshioka S, Iinuma Y, Takakura S, Fujihara N, Ichinohe T, Ishikawa T, Uchiyama T, Ichiyama S (2008) Effects on spectrum and susceptibility patterns of isolates causing bloodstream infection by restriction of fluoroquinolone prophylaxis in a hematology–oncology unit. Eur J Clin Microbiol Infect Dis 27:209–216
    Article CAS PubMed Google Scholar
  50. Engels EA, Ellis CA, Supran SE, Schmid CH, Barza M, Schenkein DP, Koc Y, Miller KB, Wong JB (1999) Early infection in bone marrow transplantation: quantitative study of clinical factors that affect risk. Clin Infect Dis 28:256–266
    Article CAS PubMed Google Scholar
  51. Ghosh I, Raina V, Kumar L, Sharma A, Bakhshi S, Thulkar S, Kapil A (2012) Profile of infections and outcome in high-risk febrile neutropenia: experience from a tertiary care cancer center in India. Med Oncol 29(2):1354–1360
    Article PubMed Google Scholar
  52. Richard P, Delangi MH, Raffi F, Espaze E, Richet H (2001) Impact of fluoroquinolone administration on the emergence of fluoroquinolone-resistant, gram-negative bacilli from gastrointestinal flora. Clin Infect Dis 32:162–166
    Article CAS PubMed Google Scholar
  53. Cheong HJ, Yoo CW, Sohn JW, Kim WJ, Kim MJ, Park SC (2001) Bacteremia due to quinolone-resistant Escherichia coli in a teaching hospital in South Korea. Clin Infect Dis 33:48–53
    Article CAS PubMed Google Scholar
  54. McDonald LC, Chen FJ, Lo HJ, Yin HC, Lu PL, Huang CH, Chen P, Lauderdale TL, Ho M (2001) Emergence of reduced susceptibility and resistance to fluoroquinolones in Escherichia coli in Taiwan and contributions of distinct selective pressures. Antimicrob Agents Chemother 45:3084–3089
    Article CAS PubMed Google Scholar
  55. Lodise TP Jr, Patel N, Kwa A, Graves J, Furuno JP, Graffunder E, Lomaestro B, McGregor JC (2007) Predictors of 30-day mortality among patients with Pseudomonas aeruginosa bloodstream infections: impact of delayed appropriate antibiotic selection. Antimicrob Agents Chemother 51(10):3510–3515
    Article CAS PubMed Google Scholar
  56. Giske CG, Monnet DL, Cars O, Carmeli Y, ReAct-Action on Antibiotic Resistance (2008) Clinical and economic impact of common multidrug-resistant gram-negative bacilli. Antimicrob Agents Chemother 52(3):813–821
    Article CAS PubMed Google Scholar
  57. Caselli D, Cesaro S, Ziino O, Zanazzo G, Manicone R, Livadiotti S, Cellini M, Frenos S, Milano GM, Cappelli B, Licciardello M, Beretta C, Aricò M, Castagnola E, Infection Study Group of the Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP) (2010) Multidrug resistant Pseudomonas aeruginosa infection in children undergoing chemotherapy and hematopoietic stem cell transplantation. Haematologica 95(9):1612–1615
    Article CAS PubMed Google Scholar

Download references