Resolvin D1 improves survival in experimental sepsis through reducing bacterial load and preventing excessive activation of inflammatory response (original) (raw)
References
Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J, Pinsky MR (2001) Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med 29:1303–1310 ArticleCASPubMed Google Scholar
Martin GS, Mannino DM, Eaton S, Moss M (2003) The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med 348:1546–1554 ArticlePubMed Google Scholar
Kumar V, Sharma A (2008) Innate immunity in sepsis pathogenesis and its modulation: new immunomodulatory targets revealed. J Chemother 20:672–683 ArticleCASPubMed Google Scholar
Chiu WC, Wang YC, Chien YW, Hou YC, Hu YM, Yeh SL (2009) Effects of dietary fish oil supplementation on cellular adhesion molecule expression and tissue myeloperoxidase activity in hypercholesterolemic mice with sepsis. J Nutr Biochem 20(4):254–260 ArticleCASPubMed Google Scholar
Krogh-Madsen R, Plomgaard P, Akerstrom T, Møller K, Schmitz O, Pedersen BK (2008) Effect of short-term intralipid infusion on the immune response during low-dose endotoxemia in humans. Am J Physiol Endocrinol Metab 294:E371–E379 ArticleCASPubMed Google Scholar
Pluess TT, Hayoz D, Berger MM, Tappy L, Revelly JP, Michaeli B, Carpentier YA, Chioléro RL (2007) Intravenous fish oil blunts the physiological response to endotoxin in healthy subjects. Intensive Care Med 33:789–797 ArticleCASPubMed Google Scholar
Serhan CN, Hong S, Gronert K, Colgan SP, Devchand PR, Mirick G, Moussignac RL (2002) Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals. J Exp Med 196:1025–1037 ArticleCASPubMed CentralPubMed Google Scholar
Spite M, Norling LV, Summers L, Yang R, Cooper D, Petasis NA, Flower RJ, Perretti M, Serhan CN (2009) Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis. Nature 461(7268):1287–1291 ArticleCASPubMed CentralPubMed Google Scholar
Hong S, Gronert K, Devchand PR, Moussignac RL, Serhan CN (2003) Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood, and glial cells. Autacoids in anti-inflammation. J Biol Chem 278:14677–14687 ArticleCASPubMed Google Scholar
Krishnamoorthy S, Recchiuti A, Chiang N, Fredman G, Serhan CN (2012) Resolvin D1 receptor stereoselectivity and regulation of inflammation and proresolving microRNAs. Am J Pathol 180(5):2018–2027 ArticleCASPubMed Google Scholar
Krishnamoorthy S, Recchiuti A, Chiang N, Yacoubian S, Lee CH, Yang R, Petasis NA, Serhan CN (2010) Resolvin D1 binds human phagocytes with evidence for proresolving receptors. Proc Natl Acad Sci U S A 107:1660–1665 ArticleCASPubMed CentralPubMed Google Scholar
Rogerio AP, Haworth O, Croze R, Oh SF, Uddin M, Carlo T, Pfeffer MA, Priluck R, Serhan CN, Levy BD (2012) Resolvin D1 and aspirin-triggered resolvin D1 promote resolution of allergic airways responses. J Immunol 189(4):1983–1991 ArticleCASPubMed CentralPubMed Google Scholar
Xu ZZ, Zhang L, Liu T, Park JY, Berta T, Yang R, Serhan CN, Ji RR (2010) Resolvins RvE1 and RvD1 attenuate inflammatory pain via central and peripheral actions. Nat Med 16(5):592–597, 1p following 597 ArticleCASPubMed CentralPubMed Google Scholar
Merched AJ, Ko K, Gotlinger KH, Serhan CN, Chan L (2008) Atherosclerosis: evidence for impairment of resolution of vascular inflammation governed by specific lipid mediators. FASEB J 22:3595–3606 ArticleCASPubMed Google Scholar
Kasuga K, Yang R, Porter TF, Agrawal N, Petasis NA, Irimia D, Toner M, Serhan CN (2008) Rapid appearance of resolvin precursors in inflammatory exudates: novel mechanisms in resolution. J Immunol 181(12):8677–8687 CASPubMed CentralPubMed Google Scholar
Liao Z, Dong J, Wu W, Yang T, Wang T, Guo L, Chen L, Xu D, Wen F (2012) Resolvin D1 attenuates inflammation in lipopolysaccharide-induced acute lung injury through a process involving the PPARgamma/NF-kappaB pathway. Respir Res 13:110 ArticleCASPubMed CentralPubMed Google Scholar
Eickmeier O, Seki H, Haworth O, Hilberath JN, Gao F, Uddin M, Croze RH, Carlo T, Pfeffer MA, Levy BD (2013) Aspirin-triggered resolvin D1 reduces mucosal inflammation and promotes resolution in a murine model of acute lung injury. Mucosal Immunol 6(2):256–266 ArticleCASPubMed CentralPubMed Google Scholar
Hsiao HM, Sapinoro RE, Thatcher TH, Croasdell A, Levy EP, Fulton RA, Olsen KC, Pollock SJ, Serhan CN, Phipps RP, Sime PJ (2013) A novel anti-inflammatory and pro-resolving role for resolvin d1 in acute cigarette smoke-induced lung inflammation. PLoS One 8(3):e58258 ArticleCASPubMed CentralPubMed Google Scholar
Hellmann J, Tang Y, Kosuri M, Bhatnagar A, Spite M (2011) Resolvin D1 decreases adipose tissue macrophage accumulation and improves insulin sensitivity in obese–diabetic mice. FASEB J 25(7):2399–2407 ArticleCASPubMed Google Scholar
Schwab JM, Chiang N, Arita M, Serhan CN (2007) Resolvin E1 and protectin D1 activate inflammation-resolution programmes. Nature 447(7146):869–874 ArticleCASPubMed CentralPubMed Google Scholar
Rittirsch D, Huber-Lang MS, Flierl MA, Ward PA (2009) Immunodesign of experimental sepsis by cecal ligation and puncture. Nat Protoc 4:31–36 ArticleCASPubMed CentralPubMed Google Scholar
Hou LC, Qin MZ, Zheng LN, Lu Y, Wang Q, Peng DR, Yu XP, Xin YC, Ji GL, Xiong LZ (2009) Severity of sepsis is correlated with the elevation of serum high-mobility group box 1 in rats. Chin Med J (Engl) 122(4):449–454 CAS Google Scholar
Dombrovskiy VY, Martin AA, Sunderram J, Paz HL (2007) Rapid increase in hospitalization and mortality rates for severe sepsis in the United States: a trend analysis from 1993 to 2003. Crit Care Med 35:1244–1250 ArticlePubMed Google Scholar
Rittirsch D, Hoesel LM, Ward PA (2007) The disconnect between animal models of sepsis and human sepsis. J Leukoc Biol 81:137–143 ArticleCASPubMed Google Scholar
Remick DG, Newcomb DE, Bolgos GL, Call DR (2000) Comparison of the mortality and inflammatory response of two models of sepsis: lipopolysaccharide vs. cecal ligation and puncture. Shock 13:110–116 ArticleCASPubMed Google Scholar
Deitch EA (2005) Rodent models of intra-abdominal infection. Shock 24(Suppl 1):19–23 ArticlePubMed Google Scholar
Wang B, Gong X, Wan JY, Zhang L, Zhang Z, Li HZ, Min S (2011) Resolvin D1 protects mice from LPS-induced acute lung injury. Pulm Pharmacol Ther 24(4):434–441 ArticlePubMed Google Scholar
Xu ZZ, Ji RR (2011) Resolvins are potent analgesics for arthritic pain. Br J Pharmacol 164(2):274–277 ArticleCASPubMed Google Scholar
Hotchkiss RS, Coopersmith CM, Karl IE (2005) Prevention of lymphocyte apoptosis—a potential treatment of sepsis? Clin Infect Dis 41(Suppl 7):S465–S469 ArticleCASPubMed Google Scholar
El Kebir D, Gjorstrup P, Filep JG (2012) Resolvin E1 promotes phagocytosis-induced neutrophil apoptosis and accelerates resolution of pulmonary inflammation. Proc Natl Acad Sci U S A 109(37):14983–14988 ArticlePubMed CentralPubMed Google Scholar
Inoue S, Unsinger J, Davis CG, Muenzer JT, Ferguson TA, Chang K, Osborne DF, Clark AT, Coopersmith CM, McDunn JE, Hotchkiss RS (2010) IL-15 prevents apoptosis, reverses innate and adaptive immune dysfunction, and improves survival in sepsis. J Immunol 184(3):1401–1409 ArticleCASPubMed CentralPubMed Google Scholar
Chiang N, Fredman G, Bäckhed F, Oh SF, Vickery T, Schmidt BA, Serhan CN (2012) Infection regulates pro-resolving mediators that lower antibiotic requirements. Nature 484(7395):524–528 ArticleCASPubMed CentralPubMed Google Scholar