Caveolin-1 expression is associated with a basal-like phenotype in sporadic and hereditary breast cancer (original) (raw)

References

  1. Williams TM, Lisanti MP. (2004) Protein family review. The caveolin proteins Genome Biol 5:214–222
    Article PubMed Google Scholar
  2. Couet J, Belanger MM, Roussel E, Drolet MC. (2001) Cell biology of caveolae and caveolin Adv Drug Deliv Rev 49:223–235
    Article PubMed CAS Google Scholar
  3. Li L, Yang G, Ebara S, Satoh T, Nasu Y, Timme TL, Ren C, Wang J, Tahir SA, Thompson TC. (2001) Caveolin-1 mediates testosterone-stimulated survival/clonal growth and promotes metastatic activities in prostate cancer cells Cancer Res 61: 4386–4392
    PubMed CAS Google Scholar
  4. Tso CL, McBride WH, Sun J, Patel B, Tsui KH, Paik SH, Gitlitz B, Caliliw R, van Ophoven A, Wu L, deKernion J, Belldegrun A. (2000) Androgen deprivation induces selective outgrowth of aggressive hormone-refractory prostate cancer clones expressing distinct cellular and molecular properties not present in parental androgen-dependent cancer cells Cancer J 6:220–233
    PubMed CAS Google Scholar
  5. Fine SW, Lisanti MP, Galbiati F, Li M. (2001) Elevated expression of caveolin-1 in adenocarcinoma of the colon Am J Clin Pathol 115:719–724
    Article PubMed CAS Google Scholar
  6. Hu YC, Lam KY, Law S, Wong J, Srivastava G. (2001) Profiling of differentially expressed cancer-related genes in esophageal squamous cell carcinoma (ESCC) using human cancer c DNA arrays: overexpression of oncogene MET correlates with tumor differentiation in ESCC Clin Cancer Res 7:3519–3525
    PubMed CAS Google Scholar
  7. Kato K, Hida Y, Miyamoto M, Hashida H, Shinohara T, Itoh T, Okushiba S, Kondo S, Katoh H. (2002) Overexpression of caveolin-1 in esophageal squamous cell carcinoma correlates with lymph node metastasis and pathologic stage Cancer 15:929–933
    Article Google Scholar
  8. Ho CC, Huang PH, Huang HY, Chen YH, Yang PC, Hsu SM. (2002) Up-regulated caveolin-1 accentuates the metastasis capability of lung adenocarcinoma by inducing filopodia formation Am J Pathol 161:1647–1656
    PubMed CAS Google Scholar
  9. Wiechen K, Diatchenko L, Agoulnik A, Scharff KM, Schober H, Arlt K, Zhumabayeva B, Siebert PD, Dietel M, Schafer R, Sers C. (2001) Caveolin-1 is down-regulated in human ovarian carcinoma and acts as a candidate tumor suppressor gene Am J Pathol 159:1635–1643
    PubMed CAS Google Scholar
  10. Sakamoto M, Kondo A, Kawasaki K, Goto T, Sakamoto H, Miyake K, Koyamatsu Y, Akiya T, Iwabuchi H, Muroya T, Ochiai K, Tanaka T, Kikuchi Y, Tenjin Y. (2001) Analysis of gene expression profiles associated with cisplatin resistance in human ovarian cancer cell lines and tissues using cDNA microarray Hum Cell 14:305–315:
    PubMed CAS Google Scholar
  11. Wiechen K, Sers C, Agoulnik A, Arlt K, Dietel M, Schlag PM, Schneider U. (2001) Down-regulation of caveolin-1, a candidate tumor suppressor gene, in sarcomas Am J Pathol 158:833–839
    PubMed CAS Google Scholar
  12. Hurlstone A FL, Reid G, Reeves JR, Fraser J, Strathdee G, Rahilly M, Parkinson E K, Black DM. (1999) Analysis of the CAVEOLIN-1 gene at human chromosome 7q31.1 in primary tumours and tumour-derived cell lines Oncogene 18:1881–1890
    Article PubMed CAS Google Scholar
  13. Hayashi K, Matsuda S, Machida K, Yamamoto T, Fukuda Y, Nimura Y, Hayakawa T, Hamaguchi M. (2001) Invasion activating caveolin-1 mutation in human scirrhous breast cancers Cancer Res 61:2361–2364
    PubMed CAS Google Scholar
  14. Hino M, Doihara H, Kobayashi K, Aoe M, Shimizu N. (2003) Caveolin-1 as tumor suppressor gene in breast cancer Surg Today 33:486–490
    PubMed CAS Google Scholar
  15. Williams TM, Cheung MW, Park DS, Razani B, Cohen AW, Muller WJ, Di Vizio D, Chopra NG, Pestell RG, Lisanti MP. (2003) Loss of caveolin-1 gene expression accelerates the development of dysplastic mammary lesions in tumor-prone transgenic mice Mol Biol Cell 14:1027–1042
    Article PubMed CAS Google Scholar
  16. Chen ST, Lin SY, Yeh KT, Kuo SJ, Chan WL, Chu YP, Chang JG. (2004) Mutational, epigenetic and expressional analyses of caveolin-1 gene in breast cancers Int J Mol Med 14:577–582
    PubMed CAS Google Scholar
  17. Williams TM, Medina F, Badano I, Hazan RB, Hutchinson J, Muller WJ, Chopra NG, Scherer PE, Pestell RG, Lisanti MP. (2004) Caveolin-1 gene disruption promotes mammary tumorigenesis and dramatically enhances lung metastasis in vivo. Role of cav-1 in cell invasiveness and matrix metalloproteinase (MMP-2/9) secretion J Biol Chem 279:51630–51646
    Article PubMed CAS Google Scholar
  18. Sloan EK, Stanley KL, Anderson RL. (2004) Caveolin-1 inhibits breast cancer growth and metastasis Oncogene 23:7893–7897
    Article PubMed CAS Google Scholar
  19. Sagara Y, Mimori K, Yoshinaga K, Tanaka F, Nishida K, Ohno S, Inoue H, Mori M. (2004) Clinical significance of caveolin-1, caveolin-2 and Her2/neu mRNA expression in human breast cancer Br J Cancer 91:959–965
    PubMed CAS Google Scholar
  20. Park S-S, Kim JE, Kim YA, Kim YC, Kim S-W. (2005) Caveolin-1 is down-regulated and inversely correlated with HER2 and EGFR expression status in invasive ductal carcinoma of the breast Histopathology 47:625–630
    Article PubMed Google Scholar
  21. Van den Eynden GG, Laere SJV, Van der Auwera I, Merajver SD, Van Marck EA, van Dam P, Vermeulen PB, Dirix LY, van Golen KL. (2005) Overexpression of caveolin-1 and -2 in cell lines and in human simples of inflammatory breast cancer Breast Cancer Res Treat 22:1–10
    Google Scholar
  22. Jones C, Mackay A, Grigoriadis A, Cossu A, Reis-Filho JS, Fulford L, Dexter T, Davies S, Bulmer K, Ford E, Parry S, Budroni M, Palmieri G, Neville AM, O’Hare MJ, Lakhani SR. (2004) Expression profiling of purified normal human luminal and myoepithelial breast cells: identification of novel prognostic markers for breast cancer Cancer Res 64:3037–3045
    Article PubMed CAS Google Scholar
  23. Perou CM, Sorlie T, Eisen MB, van de Rijn M, Jeffrey SS, Rees CA, Pollack JR, Ross DT, Johnsen H, Akslen LA, Fluge O, Pergamenschikov A, Williams C, Zhu SX, Lonning PE, Borresen-Dale AL, Brown PO, Botstein D. (2000) Molecular portraits of human breast tumours Nature 406:747–752
    Article PubMed CAS Google Scholar
  24. Gusterson BA, Ross DT, Heath VJ, Stein T. (2005) Basal cytokeratins and their relationship to the cellular origin and functional classification of breast cancer Breast Cancer Res 7:143–148
    Article PubMed CAS Google Scholar
  25. Tsuda H, Takarabe T, Hasegawa F, Fukutomi T, Hirohashi S. (2000) Large, central acellular zones indicating myoepithelial tumor differentiation in high-grade invasive ductal carcinomas as markers of predisposition to lung and brain metastases Am J Surg Pathol 24:197–202
    Article PubMed CAS Google Scholar
  26. Jacquemier J, Padovani L, Rabayrol L, Lakhani SR, Penault-Llorca F, Denoux Y, Fiche M, Figueiro P, Maisougrosse V, Ledonssal V, Martinez Penuela J, Vdvarhely N, El Makdissi G, Ginestier C, Geneix J, Charafe-Jauffret E, Xerri L, Eisinger F, Birnbaum D, Sobol H. (2005) Typical medullary breast carcinomas have a basal/myoepithelial phenotype J Pathol 207:260–268
    Article PubMed CAS Google Scholar
  27. Livasy CA, Karaca G, Nanda R, Tretiakova MS, Olopade OI, Moore DT, Perou CM. (2006) Phenotypic evaluation of the basal-like subtype of invasive breast carcinoma Modern Pathol 19: 264–271
    Article CAS Google Scholar
  28. Sorlie T, Perou CM, Tibshirani R, Aas T, Geisler S, Johnsen H, Hastie T, Eisen MB, van de Rijn M, Jeffrey SS, Thorsen T, Quist H, Matesse JC, Brown PO, Botstein D, Eystein-Lonning P, Borresen- Dale AL. (2001) Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications Proc Natl Acad Sci USA 98:10869–10874
    Article PubMed CAS Google Scholar
  29. Van’t Veer LJ, Dal H, van de Vijver MJ, He YD, Hart AA, Mao M, Meterse HL, van der Kooy K, Marton MJ, Witteveen AT, Schreiber GJ, Kerkhoven RM, Roberts C, Linsley PS, Bernards R, Friend SH. (2002) Gene expression profiling predicts clinical outcome of breast cancer Nature 415:530–535
    Article CAS Google Scholar
  30. Rouzier N, Perou CM, Symmans WF, Ibrahim N, Cristofanilli M, Anderson K, Hess KR, Stec J, Ayers M, Wagner P, Morandi P, Fan C, Rabiul I, Ross JS, Hortobagyi GN, Pusztai L. (2005) Breast cancer molecular subtypes respond differently to preoperative chemotherapy Clin Cancer Res 11:5678–5685
    Article PubMed CAS Google Scholar
  31. Rodríguez-Pinilla SM, Sarrió D, Honrado E, Hardisson D, Calero F, Benitez J, Palacios J: Prognostic significance of basal-like phenotype and fascin expression in node-negative invasive breast carcinomas. Clin Cancer Res, 12: 2006
  32. Sorlie T, Tibshirani R, Parker J, Hastie T, Marron JS, Nobel A, Deng S, Johnsen H, Pesich R, Geisler S, Demeler J, Perou CM, Lonning PE, Brown PO, Borresen-Dale AL, Botstein D. (2003) Repeated observation of breast tumor subtypes in independent gene expression data sets Proc Natl Acad Sci USA 100:8418–8423
    Article PubMed CAS Google Scholar
  33. Lakhani SR, Reis-Filho JS, Fulford L, Penault-Llorca F, van der Vijver M, Parry S, Bishop T, Benitez J, Rivas C, Bignon YJ, Chang-Claude J, Hamann U, Cornelisse CJ, Devilee P, Beckmann MW, Nestle-Kramling C, Daly PA, Haites N, Varley J, Lalloo F, Evans G, Maugard C, Meijers-Heijboer H, Klijn JG, Olah E, Gusterson BA, Pilotti S, Radice P, Scherneck S, Sobol H, Jacquemier J, Wagner T, Peto J, Stratton MR, McGuffong L, Easton DF. (2005) Breast Cancer linkage consortium. Prediction of BRCA1 status in patients with breast cancer using estrogen receptor and basal phenotype Clin Cancer Res 11:5175–5180
    Article PubMed CAS Google Scholar
  34. Nielsen TO, Hsu FD, Jensen K, Cheang M, Karaca G, Hu Z, Hernandez-Boussard T, Livasy C, Cowan D, Dressler L, Akslen LA, Ragaz J, Gown AM, Gilks CB, van de Rijn M, Perou CM. (2004) Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma Clin Cancer Res 10:5367–5374
    Article PubMed CAS Google Scholar
  35. Palacios J, Honrado E, Osorio A, Cazorla A, Sarrio D, Barroso A, Rodríguez S, Cigudosa JC, Diez O, Alonso C, Lerma E, Dopazo J, Rivas C, Benitez J. (2005) Phenotypic characterization of BRCA1 and BRCA2 tumors based in a tissue microarray study with 37 immunohistochemical markers Breast Cancer Res Treat 90:5–14
    Article PubMed CAS Google Scholar
  36. Honrado E, Benitez J, Palacios J. (2005) The molecular pathology of hereditary breast cancer: genetic testing and therapeutic implications Mod Pathol 18:1305–1320
    Article PubMed CAS Google Scholar
  37. Sontiriou C, Neo S-Y, McShane LM, Korn EL, Long PM, Jazaeri A, Martiat P, Fox SB, Harris AL, Liu ET. (2003) Breast cancer classification and prognosis based on gene expression profiles from a population-based study Proc Natl Acad Sci USA 100:10393–10398
    Article Google Scholar
  38. Charafe-Jauffret E, Ginestier C, Monville F, Finetti P, Adélaïde J, Cervera N, Fekairi S, Xerri L, Jacquemier J, Birnbaum D, Bertucci F: Gene expression profiling of breast cell lines identifies potential new basal markers. Oncogene 24: 1–12, 2005
    Google Scholar
  39. Sunaga N, Miyajima K, Suzuki M, Sato M, White MA, Ramirez RD, Shay JW, Gazdar AF, Minna JD. (2004) Different roles for caveolin-1 in the development of non-small cell lung cancer versus small cell lung cancer Cancer Res 64:4277–4285
    Article PubMed CAS Google Scholar
  40. Yang G, Truong LD, Timme TL, Ren C, Wheeler TM, Park SH, Nasu Y, Bangma CH, Kattan MW, Scardino PT, Thompson TC. (1998) Elevated expression of caveolin is associated with prostate and breast cancer Clin Cancer Res 4:1873–1880
    PubMed CAS Google Scholar
  41. Foulkes WD, Stefansson IM, Chappuis PO, Begin LR, Goffin JR, Wong N, Trudel M, Akslen LA. (2003) Germline BRCA1 mutations and a basal epithelial phenotype in breast cancer J Natl Cancer Inst 95:1482–1485
    PubMed CAS Google Scholar
  42. Foulkes WD, Brunet JS, Stefansson IM, Straume O, Chappuis PO, Begin LR, Hamel N, Goffin JR, Wong N, Trudel M, Kapusta L, Porter P, Akslen LA. (2004) The prognostic implication of the basal-like (cyclin-E high/p27 low/p53+/glomeruloid-microvascular-proliferation+) phenotype of BRCA1-related breast cancers Cancer Res 64:830–835
    Article PubMed CAS Google Scholar
  43. van der Groep P, Bouter A, van der Zanden R, Menko FH, Buerger H, Verheijen RH, van der Wall E, van Dieest PJ. (2004) Re: Germline BRCA1 mutations and a basal epithelial phenotype in breast cancer J Natl Cancer Inst 96:712–713
    PubMed Google Scholar
  44. Palacios J, Honrado E, Osorio A, Diez O, Rivas C, Benitez J: Re: Germline mutations and a basal epithelial phenotype in breast cancer. J Natl Cancer Inst 96: 712–714, 2004
    Google Scholar

Download references