Heterogeneous Distribution of Kir3 Potassium Channel Proteins Within Dopaminergic Neurons in the Mesencephalon of the Rat Brain (original) (raw)

References

• Adelbrecht, C., Murer, M. G., Lauritzen, I., Lesage, F., Ladzunski, M., Agid, Y., and Raisman-Vozari, R. (1997). An immunocytochemical study of a G-protein-gated inward rectifier K+ channel (GIRK2) in the weaver mouse mesencephalon. Neuroreport **8:**969–974.
  Article CAS PubMed Google Scholar
• Andres, K. H., and von Düring, M. (1981). General methods for characterization of brain regions. In Heym, C. H., and Forssmann, W. G. (eds.), Techniques in Neuroanatomical Research, Springer, Heidelberg Berlin New York, pp. 100–108.
  Chapter Google Scholar
• Bosboom, J. L., Stoffers, D., and Wolters, E. C. (2004). Cognitive dysfunction and dementia in Parkinson's disease. J. Neural. Transm. **111:**1303–1315.
  Article CAS PubMed Google Scholar
• Chen, S. C., Ehrhard, P., Goldowitz, D., and Smeyne, R. J. (1997). Developmental expression of the GIRK family of inward rectifying potassium channels: Implications for abnormalities in the weaver mutant mouse. Brain Res. **778:**251–264.
  Article CAS PubMed Google Scholar
• Cheney, J. A., Weisser, J. D., Bareyre, F. M., Laurer, H. L., Saatman, K. E., Raghupathi, R., Gribkoff, V., Starrett, J. E.,Jr., and McIntosh, T. K. (2001). The maxi-K channel opener BMS-204352 attenuates regional cerebral edema and neurologic motor impairment after experimental brain injury. J. Cereb. Blood Flow Metab. **21:**396–403.
  Article CAS PubMed Google Scholar
• Dissmann, E., Wischmeyer, E., Spauschus, A., von Pfeil, D., Karschin, C., and Karschin, A. (1996). Functional expression and cellular mRNA localization of a G protein-activated K+ inward rectifier isolated from rat brain. Biochem. Biophys. Res. Commun. **223:**474–479.
  Article CAS PubMed Google Scholar
• Drake, C. T., Bausch, S. B., Milner, T. A., and Chavkin, C. (1997). GIRK1 immunoreactivity is present predominantly in dendrites, dendritic spines, and somata in the CA1 region of the hippocampus. Proc. Natl. Acad. Sci. U.S.A. **94:**1007–1012.
  Article CAS PubMed PubMed Central Google Scholar
• Duvoisin, R. C. (1999). Genetic and environmental factors in Parkinson's disease. Adv. Neurol. **80:**161–163.
  CAS PubMed Google Scholar
• Golanov, E. V., and Zhou, P. (2003). Neurogenic neuroprotection. Cell. Mol. Neurobiol. **23:**651–663.
  Article PubMed PubMed Central Google Scholar
• Gonzalez-Hernandez, T., Barroso-Chinea, P., Acevedo, A., Salido, E., and Rodriguez, M. (2001). Colocalization of tyrosine hydroxylase and GAD65 mRNA in mesostriatal neurons. Eur. J. Neurosci. **13:**57–67.
  Article CAS PubMed Google Scholar
• Gruber, A., and Zingales, B. (1995). Alternative method to remove antibacterial antibodies from antisera used for screening of expression libraries. Biotechniques **19:**28–30.
  CAS PubMed Google Scholar
• Haber, S. N., and Fudge, J. L. (1997). The primate substantia nigra and VTA: Integrative circuitry and function. Crit. Rev. Neurobiol. **11:**323–342.
  Article CAS PubMed Google Scholar
• Harashima, C., Jacobowitz, D. M., Witta, J., Borke, R. C., Best, T. K., Siarey, R. J., and Galdzicki, Z. (2006). Abnormal expression of the G-protein-activated inwardly rectifying potassium channel 2 (GIRK2) in hippocampus, frontal cortex, and substantia nigra of Ts65Dn mouse: A model of Down syndrome. J. Comp. Neurol. **494:**815–833.
  Article CAS PubMed PubMed Central Google Scholar
• Harlow, E., and Lane, D. (eds.) (1988). Antibodies: A Laboratory Manual, CSH Laboratory Press, Cold Spring Harbor, NY.
• Hirsch, E. C., Faucheux, B., Damier, P., Mouatt-Prigent, A., and Agid, Y. (1997). Neuronal vulnerability in Parkinson's disease. J. Neural. Transm. Suppl. **50:**79–88.
  Article CAS PubMed Google Scholar
• Iizuka, M., Tsunenari, I., Momota, Y., Akiba, I., and Kono, T. (1997). Localization of a G-protein-coupled inwardly rectifying K+ channel, CIR, in the rat brain. Neuroscience **77:**1–13.
  Article CAS PubMed Google Scholar
• Inanobe, A., Horio, Y., Fujita, A., Tanemoto, M., Hibino, H., Inageda, K., and Kurachi, Y. (1999a). Molecular cloning and characterization of a novel splicing variant of the Kir3.2 subunit predominantly expressed in mouse testis. J. Physiol. **521:**19–30.
  Article CAS PubMed PubMed Central Google Scholar
• Inanobe, A., Yoshimoto, Y., Horio, Y., Morishige, K. I., Hibino, H., Matsumoto, S., Tokunaga, Y., Maeda, T., Hata, Y., Takai, Y., and Kurachi, Y. (1999b). Characterization of G-protein-gated K+ channels composed of Kir3.2 subunits in dopaminergic neurons of the substantia nigra. J. Neurosci. **19:**1006–1017.
  Article CAS PubMed PubMed Central Google Scholar
• Karschin, C., Dissmann, E., Stuhmer, W., and Karschin, A. (1996). IRK(1–3) and GIRK(1–4) inwardly rectifying K+ channel mRNAs are differentially expressed in the adult rat brain. J. Neurosci. **16:**3559–3570.
  Article CAS PubMed PubMed Central Google Scholar
• Kobayashi, T., Washiyama, K., and Ikeda, K. (2004). Inhibition of G protein-activated inwardly rectifying K+ channels by various antidepressant drugs. Neuropsychopharmacology **29:**1841–1851.
  Article CAS PubMed Google Scholar
• Liao, Y. J., Jan, Y. N., and Jan, L. Y. (1996). Heteromultimerization of G-protein-gated inwardly rectifying K+ channel proteins GIRK1 and GIRK2 and their altered expression in weaver brain. J. Neurosci. **16:**7137–7150.
  Article CAS PubMed PubMed Central Google Scholar
• Liss, B., Neu, A., and Roeper, J. (1999b). The weaver mouse gain-of-function phenotype of dopaminergic midbrain neurons is determined by coactivation of wvGirk2 and K-ATP channels. J. Neurosci. **19:**8839–8848.
  Article CAS PubMed PubMed Central Google Scholar
• Liss, B., Bruns, R., and Roeper, J. (1999a). Alternative sulfonylurea receptor expression defines metabolic sensitivity of K-ATP channels in dopaminergic midbrain neurons. EMBO J. **18:**833–846.
  Article CAS PubMed PubMed Central Google Scholar
• Liss, B., and Roeper, J. (2001). Molecular physiology of neuronal K-ATP channels. Mol. Membr. Biol. **18:**117–127.
  Article CAS PubMed Google Scholar
• McRitchie, D. A., Hardman, C. D., and Halliday, G. M. (1996). Cytoarchitectural distribution of calcium binding proteins in midbrain dopaminergic regions of rats and humans. J. Comp. Neurol. **364:**121–150.
  Article CAS PubMed Google Scholar
• Mendez, I., Sanchez-Pernaute, R., Cooper, O., Vinuela, A., Ferrari, D., Bjorklund, L., Dagher, A., and Isacson, O. (2005). Cell type analysis of functional fetal dopamine cell suspension transplants in the striatum and substantia nigra of patients with Parkinson's disease. Brain **128:**1498–1510.
  Article PubMed Google Scholar
• Miyashita, T., and Kubo, Y. (1997). Localization and developmental changes of the expression of two inward rectifying K(+)-channel proteins in the rat brain. Brain Res. **750:**251–263.
  Article CAS PubMed Google Scholar
• Morgan, A. D., Carroll, M. E., Loth, A. K., Stoffel, M., and Wickman, K. (2003). Decreased cocaine self-administration in Kir3 potassium channel subunit knockout mice. Neuropsychopharmacology **28:**932–938.
  Article CAS PubMed Google Scholar
• Murer, G., Adelbrecht, C., Lauritzen, I., Lesage, F., Lazdunski, M., Agid, Y., and Raisman-Vozari, R. (1997). An immunocytochemical study on the distribution of two G-protein-gated inward rectifier potassium channels (GIRK2 and GIRK4) in the adult rat brain. Neuroscience **80:**345–357.
  Article CAS PubMed Google Scholar
• Nelson, C. S., Marinoand, J. L., and Allen, C. N. (1997). Cloning and characterization of Kir3.1 (GIRK1) C-terminal alternative splice variants. Brain Res. Mol. Brain Res. **46:**185–196.
  Article CAS PubMed Google Scholar
• Pompeia, C., Ortis, F., and Armelin, M. C. (1996). Immunopurification of polyclonal antibodies to recombinant proteins of the same gene family. Biotechniques **21:**986–990.
  Article CAS PubMed Google Scholar
• Ponce, A., Bueno, E., Kentros, C., Vega-Saenz de Miera, E., Chow, A., Hillman, D., Chen, S., Zhu, L., Wu, M. B., Wu, X., Rudy, B., and Thornhill, W. B. (1996). G-protein-gated inward rectifier K+ channel proteins (GIRK1) are present in the soma and dendrites as well as in nerve terminals of specific neurons in the brain. J. Neurosci. **16:**1990–2001.
  Article CAS PubMed PubMed Central Google Scholar
• Prüss, H., Derst, C., Lommel, R., and Veh, R. W. (2005). Differential distribution of individual subunits of strongly inwardly rectifying potassium channels (Kir2 family) in rat brain. Mol. Brain Res. **139:**63–79.
  Article PubMed Google Scholar
• Prüss, H., Wenzel, M., Eulitz, D., Thomzig, A., Karschin, A., and Veh, R. W. (2003). Kir2 potassium channels in rat striatum are strategically localized to control basal ganglia function. Mol. Brain Res. **110:**203–219.
  Article PubMed Google Scholar
• Schein, J. C., Hunter, D. D., and Roffler-Tarlov, S. (1998). Girk2 expression in the ventral midbrain, cerebellum, and olfactory bulb and its relationship to the murine mutation weaver. Dev. Biol. **204:**432–450.
  Article CAS PubMed Google Scholar
• Shi, R., and Blight, A. R. (1997). Differential effects of low and high concentrations of 4-aminopyridine on axonal conduction in normal and injured spinal cord. Neuroscience **77:**553–562.
  Article CAS PubMed Google Scholar
• Spauschus, A., Lentes, K. U., Wischmeyer, E., Dissmann, E., Karschin, C., and Karschin, A. (1996). A G-protein-activated inwardly rectifying K+ channel (GIRK4) from human hippocampus associates with other GIRK channels. J. Neurosci. **16:**930–938.
  Article CAS PubMed PubMed Central Google Scholar
• Standen, N. B., Quayle, J. M., Davies, N. W., Brayden, J. E., Huang, Y., and Nelson, M. T. (1989). Hyperpolarizing vasodilators activate ATP-sensitive K+ channels in arterial smooth muscle. Science **245:**177–180.
  Article CAS PubMed Google Scholar
• Sturgess, N. C., Ashford, M. L., Cook, D. L., and Hales, C. N. (1985). The sulphonylurea receptor may be an ATP-sensitive potassium channel. Lancet **2:**474–475.
  Article CAS PubMed Google Scholar
• Surmeier, D. J., Mermelstein, P. G., and Goldowitz, D. (1996). The weaver mutation of GIRK2 results in a loss of inwardly rectifying K+ current in cerebellar granule cells. Proc. Natl. Acad. Sci. U.S.A. **93:**11191–11195.
  Article CAS PubMed PubMed Central Google Scholar
• Swanson, L. W. (1982). The projections of the ventral tegmental area and adjacent regions: A combined fluorescent retrograde tracer and immunofluorescence study in the rat. Brain Res. Bull. **9:**321–353.
  Article CAS PubMed Google Scholar
• Thompson, L., Barraud, P., Andersson, E., Kirik, D., and Bjorklund, A. (2005). Identification of dopaminergic neurons of nigral and ventral tegmental area subtypes in grafts of fetal ventral mesencephalon based on cell morphology, protein expression, and efferent projections. J. Neurosci. **25:**6467–6477.
  Article CAS PubMed PubMed Central Google Scholar
• Thomzig, A., Laube, G., Pruss, H., and Veh, R. W. (2005). Pore-forming subunits of K-ATP channels, Kir6.1 and Kir6.2, display prominent differences in regional and cellular distribution in the rat brain. J. Comp. Neurol. **484:**313–330.
  Article CAS PubMed Google Scholar
• Wickenden, A. (2002). K(+) channels as therapeutic drug targets. Pharmacol. Ther. **94:**157–182.
  Article CAS PubMed Google Scholar
• Wickenden, A. D., Yu, W., Zou, A., Jegla, T., and Wagoner, P. K. (2000). Retigabine, a novel anti-convulsant, enhances activation of KCNQ2/Q3 potassium channels. Mol. Pharmacol. **58:**591–600.
  Article CAS PubMed Google Scholar
• Wickman, K., Karschin, C., Karschin, A., Picciotto, M. R., and Clapham, D. E. (2000). Brain localization and behavioral impact of the G-protein-gated K+ channel subunit GIRK4. J. Neurosci. **20:**5608–5615.
  Article CAS PubMed PubMed Central Google Scholar
• Wischmeyer, E., Döring, F., Wischmeyer, E., Spauschus, A., Thomzig, A., Veh, R. W., and Karschin, A. (1997). Subunit interactions in the assembly of neuronal Kir3.0 inwardly rectifying K+ channels. Mol. Cell. Neurosci. **9:**194–206.
  Article CAS PubMed Google Scholar
• Yamada, K., Ji, J. J., Yuan, H., Miki, T., Sato, S., Horimoto, N., Shimizu, T., Seino, S., and Inagaki, N. (2001). Protective role of ATP-sensitive potassium channels in hypoxia-induced generalized seizure. Science **292:**1543–1546.
  Article CAS PubMed Google Scholar

Download references