Inflammation, coagulation and risk of locomotor disability in elderly women: findings from the British Women’s Heart and Health Study (original) (raw)
Stuck AE, Walthert JM, Nikolaus T, Bula CJ, Hohmann C, Beck JC. Risk factors for functional status decline in community-living elderly people: a systematic literature review. Soc Sci Med. 1999;48(4):445–69. ArticlePubMedCAS Google Scholar
Ebrahim S, Wannamethee SG, Whincup P, Walker M, Shaper AG. Locomotor disability in a cohort of British men: the impact of lifestyle and disease. Int J Epidemiol. 2000;29(3):478–86. ArticlePubMedCAS Google Scholar
Rautio N, Adamson J, Heikkinen E, Ebrahim S. Associations of socio-economic position and disability among older women in Britain and Jyvaskyla, Finland. Arch Gerontol Geriatr. 2006;42(2):141–55. ArticlePubMed Google Scholar
Chung HY, Cesari M, Anton S, Marzetti E, Giovannini S, Seo AY, et al. Molecular inflammation: underpinnings of aging and age-related diseases. Ageing Res Rev. 2009;8(1):18–30. ArticlePubMedCAS Google Scholar
Singh T, Newman AB. Inflammatory markers in population studies of aging. Ageing Res Rev. 2011;10(3):319–29. ArticlePubMedCAS Google Scholar
Cohen HJ, Harris T, Pieper CF. Coagulation and activation of inflammatory pathways in the development of functional decline and mortality in the elderly. Am J Med. 2003;114(3):180–7. ArticlePubMed Google Scholar
Ferrucci L, Harris TB, Guralnik JM, Tracy RP, Corti MC, Cohen HJ, et al. Serum IL-6 level and the development of disability in older persons. J Am Geriatr Soc. 1999;47(6):639–46. PubMedCAS Google Scholar
Penninx BW, Kritchevsky SB, Newman AB, Nicklas BJ, Simonsick EM, Rubin S, et al. Inflammatory markers and incident mobility limitation in the elderly. J Am Geriatr Soc. 2004;52(7):1105–13. ArticlePubMed Google Scholar
Kuo HK, Bean JF, Yen CJ, Leveille SG. Linking C-reactive protein to late-life disability in the National Health and Nutrition Examination Survey (NHANES) 1999–2002. J Gerontol A Biol Sci Med Sci. 2006;61(4):380–7. ArticlePubMed Google Scholar
Brinkley TE, Leng X, Miller ME, Kitzman DW, Pahor M, Berry MJ, et al. Chronic inflammation is associated with low physical function in older adults across multiple comorbidities. J Gerontol A Biol Sci Med Sci. 2009;64(4):455–61. ArticlePubMed Google Scholar
Cesari M, Penninx BW, Pahor M, Lauretani F, Corsi AM, Rhys Williams g, et al. Inflammatory markers and physical performance in older persons: the InCHIANTI study. J Gerontol A Biol Sci Med Sci. 2004;59(3):242–8. ArticlePubMed Google Scholar
McDermott MM, Guralnik JM, Greenland P, Green D, Liu K, Ridker PM, et al. Inflammatory and thrombotic blood markers and walking-related disability in men and women with and without peripheral arterial disease. J Am Geriatr Soc. 2004;52(11):1888–94. ArticlePubMed Google Scholar
Visser M, Pahor M, Taaffe DR, Goodpaster BH, Simonsick EM, Newman AB, et al. Relationship of interleukin-6 and tumor necrosis factor-alpha with muscle mass and muscle strength in elderly men and women: the Health ABC Study. J Gerontol A Biol Sci Med Sci. 2002;57(5):M326–32. ArticlePubMed Google Scholar
Walston J, McBurnie MA, Newman A, Tracy RP, Kop WJ, Hirsch CH, et al. Frailty and activation of the inflammation and coagulation systems with and without clinical comorbidities: results from the Cardiovascular Health Study. Arch Intern Med. 2002;162(20):2333–41. ArticlePubMed Google Scholar
Barzilay JI, Blaum C, Moore T, Xue QL, Hirsch CH, Walston JD, et al. Insulin resistance and inflammation as precursors of frailty: the Cardiovascular Health Study. Arch Intern Med. 2007;167(7):635–41. ArticlePubMed Google Scholar
Reiner AP, Aragaki AK, Gray SL, Wactawski-Wende J, Cauley JA, Cochrane BB, et al. Inflammation and thrombosis biomarkers and incident frailty in postmenopausal women. Am J Med. 2009;122(10):947–54. ArticlePubMedCAS Google Scholar
Lawlor DA, Bedford C, Taylor M, Ebrahim S. Geographical variation in cardiovascular disease, risk factors, and their control in older women: British Women’s Heart and Health Study. J Epidemiol Community Health. 2003;57(2):134–40. ArticlePubMedCAS Google Scholar
Adamson J, Lawlor DA, Ebrahim S. Chronic diseases, locomotor activity limitation and social participation in older women: cross sectional survey of British Women’s Heart and Health Study. Age Ageing. 2004;33(3):293–8. ArticlePubMed Google Scholar
Cronbach LJ. Coefficient alpha and the internal structure of tests. Psychometrika. 1951;16(3):297–334. Article Google Scholar
Gaunt TR, Lowe GDO, Lawlor DA, Casas JP, Day INM. A gene-centric analysis of activated partial thromboplastin time and activated protein C resistance using the Human CVD focused genotyping array (submitted).
Jefferis BJ, Lowe GD, Welsh P, Rumley A, Lawlor DA, Ebrahim S, et al. Secondhand smoke (SHS) exposure is associated with circulating markers of inflammation and endothelial function in adult men and women. Atherosclerosis. 2010;208(2):550–6. ArticlePubMedCAS Google Scholar
Lawlor DA, Davey Smith G, Patel R, Ebrahim S. Life-course socioeconomic position, area deprivation, and coronary heart disease: findings from the British Women’s Heart and Health Study. Am J Public Health. 2005;95(1):91–7. ArticlePubMed Google Scholar
Khaw KT, Wareham N, Bingham S, Welch A, Luben R, Day N. Combined impact of health behaviours and mortality in men and women: the EPIC-Norfolk prospective population study. PLoS Med. 2008;5(1):e12. ArticlePubMed Google Scholar
Leng GC, Fowkes FG. The Edinburgh Claudication Questionnaire: an improved version of the WHO/Rose Questionnaire for use in epidemiological surveys. J Clin Epidemiol. 1992;45(10):1101–9. ArticlePubMedCAS Google Scholar
EuroQol Group. EQ-5D: a standardised instrument for use as a measure of health outcome. 2007. http://www.euroqol.org.
Rabin R, de Charro F. EQ-5D: a measure of health status from the EuroQol Group. Ann Med. 2001;33(5):337–43. ArticlePubMedCAS Google Scholar
Tas U, Verhagen AP, Bierma-Zeinstra SM, Hofman A, Odding E, Pols HA, et al. Incidence and risk factors of disability in the elderly: the Rotterdam Study. Prev Med. 2007;44(3):272–8. ArticlePubMed Google Scholar
Royston P. Multiple imputation of missing values. Stata J. 2004;4:227–41. Google Scholar
Sterne JA, White IR, Carlin JB, Spratt M, Royston P, Kenward MG, et al. Multiple imputation for missing data in epidemiological and clinical research: potential and pitfalls. BMJ. 2009;338:b2393. ArticlePubMed Google Scholar
Ebrahim S, Davey Smith G. Mendelian randomization: can genetic epidemiology help redress the failures of observational epidemiology? Hum Genet. 2008;123(1):15–33. ArticlePubMed Google Scholar
Smith GD, Ebrahim S. Mendelian randomization: prospects, potentials, and limitations. Int J Epidemiol. 2004;33(1):30–42. ArticlePubMed Google Scholar
Adamson J, Beswick A, Ebrahim S. Is stroke the most common cause of disability? J Stroke Cerebrovasc Dis. 2004;13(4):171–7. ArticlePubMed Google Scholar
Martin J, Meltzer H, Elliot D. The prevalence of disability among adults: OPCS surveys of disability in Great Britain. London: HMSO; 1988
International Classification of Functioning, Disability and Health. 2001.
Penninx BW, Abbas H, Ambrosius W, Nicklas BJ, Davis C, Messier SP, et al. Inflammatory markers and physical function among older adults with knee osteoarthritis. J Rheumatol. 2004;31(10):2027–31. PubMed Google Scholar
Jefferis BJ, Whincup PH, Welsh P, Wannamethee SG, Rumley A, Lennon LT, et al. Circulating TNFalpha levels in older men and women do not show independent prospective relations with MI or stroke. Atherosclerosis. 2009;205(1):302–8. ArticlePubMedCAS Google Scholar
Colbert LH, Visser M, Simonsick EM, Tracy RP, Newman AB, Kritchevsky SB, et al. Physical activity, exercise, and inflammatory markers in older adults: findings from the Health, Aging and Body Composition Study. J Am Geriatr Soc. 2004;52(7):1098–104. ArticlePubMed Google Scholar
Wannamethee SG, Lowe GD, Whincup PH, Rumley A, Walker M, Lennon L. Physical activity and hemostatic and inflammatory variables in elderly men. Circulation. 2002;105(15):1785–90. ArticlePubMed Google Scholar
Jankord R, Jemiolo B. Influence of physical activity on serum IL-6 and IL-10 levels in healthy older men. Med Sci Sports Exerc. 2004;36(6):960–4. ArticlePubMedCAS Google Scholar
Miller GD, Nicklas BJ, Loeser RF. Inflammatory biomarkers and physical function in older, obese adults with knee pain and self-reported osteoarthritis after intensive weight-loss therapy. J Am Geriatr Soc. 2008;56(4):644–51. ArticlePubMed Google Scholar