Systemic delivery of neutralizing antibody targeting CCL2 for glioma therapy (original) (raw)
Mizutani K, Sud S, McGregor NA et al (2009) The chemokine CCL2 increases prostate tumor growth and bone metastasis through macrophage and osteoclast recruitment. Neoplasia 11:1235–1242 PubMedCAS Google Scholar
Huang B, Lei Z, Zhao J et al (2007) CCL2/CCR2 pathway mediates recruitment of myeloid suppressor cells to cancers. Cancer Lett 252:86–92 ArticlePubMedCAS Google Scholar
Vanderkerken K, Vande BI, Eizirik DL et al (2002) Monocyte chemoattractant protein-1 (MCP-1), secreted by bone marrow endothelial cells, induces chemoattraction of 5T multiple myeloma cells. Clin Exp Metastasis 19:87–90 ArticlePubMedCAS Google Scholar
Ohta M, Kitadai Y, Tanaka S et al (2002) Monocyte chemoattractant protein-1 expression correlates with macrophage infiltration and tumor vascularity in human esophageal squamous cell carcinomas. Int J Cancer 102:220–224 ArticlePubMedCAS Google Scholar
Valkovic T, Lucin K, Krstulja M, Dobi-Babic R, Jonjic N (1998) Expression of monocyte chemotactic protein-1 in human invasive ductal breast cancer. Pathol Res Pract 194:335–340 PubMedCAS Google Scholar
Lebrecht A, Grimm C, Lantzsch T et al (2004) Monocyte chemoattractant protein-1 serum levels in patients with breast cancer. Tumour Biol 25:14–17 ArticlePubMedCAS Google Scholar
Loberg RD, Ying C, Craig M, Yan L, Snyder LA, Pienta KJ (2007) CCL2 as an important mediator of prostate cancer growth in vivo through the regulation of macrophage infiltration. Neoplasia 9:556–562 ArticlePubMedCAS Google Scholar
Lin EY, Nguyen AV, Russell RG, Pollard JW (2001) Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy. J Exp Med 193:727–740 ArticlePubMedCAS Google Scholar
Sweet MJ, Campbell CC, Sester DP et al (2002) Colony-stimulating factor-1 suppresses responses to CpG DNA and expression of toll-like receptor 9 but enhances responses to lipopolysaccharide in murine macrophages. J Immunol 168:392–399 PubMedCAS Google Scholar
Scholl SM, Pallud C, Beuvon F et al (1994) Anti-colony-stimulating factor-1 antibody staining in primary breast adenocarcinomas correlates with marked inflammatory cell infiltrates and prognosis. J Natl Cancer Inst 86:120–126 ArticlePubMedCAS Google Scholar
Gabrilovich DI, Nagaraj S (2009) Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol 9:162–174 ArticlePubMedCAS Google Scholar
Talmadge JE, Donkor M, Scholar E (2007) Inflammatory cell infiltration of tumors: Jekyll or Hyde. Cancer Metastasis Rev 26:373–400 ArticlePubMed Google Scholar
Ostrand-Rosenberg S (2010) Myeloid-derived suppressor cells: more mechanisms for inhibiting antitumor immunity. Cancer Immunol Immunother 59(10):1593–1600 ArticlePubMed Google Scholar
Yoshimura T, Robinson EA, Tanaka S, Appella E, Kuratsu J, Leonard EJ (1989) Purification and amino acid analysis of two human glioma-derived monocyte chemoattractants. J Exp Med 169:1449–1459 ArticlePubMedCAS Google Scholar
Yoshimura T, Robinson EA, Tanaka S, Appella E, Leonard EJ (1989) Purification and amino acid analysis of two human monocyte chemoattractants produced by phytohemagglutinin-stimulated human blood mononuclear leukocytes. J Immunol 142:1956–1962 PubMedCAS Google Scholar
Graeber MB, Scheithauer BW, Kreutzberg GW (2002) Microglia in brain tumors. GLIA 40:252–259 ArticlePubMed Google Scholar
Takeshima H, Kuratsu J, Takeya M, Yoshimura T, Ushio Y (1994) Expression and localization of messenger RNA and protein for monocyte chemoattractant protein-1 in human malignant glioma. J Neurosurg 80:1056–1062 ArticlePubMedCAS Google Scholar
Desbaillets I, Tada M, De Tribolet N, Diserens AC, Hamou MF, Van Meir EG (1994) Human astrocytomas and glioblastomas express monocyte chemoattractant protein-1 (MCP-1) in vivo and in vitro. Int J Cancer 58:240–247 ArticlePubMedCAS Google Scholar
Leung SY, Wong MP, Chung LP, Chan AS, Yuen ST (1997) Monocyte chemoattractant protein-1 expression and macrophage infiltration in gliomas. Acta Neuropathol (Berl) 93:518–527 ArticleCAS Google Scholar
Jordan JT, Sun W, Hussain SF, Deangulo G, Prabhu SS, Heimberger AB (2008) Preferential migration of regulatory T cells mediated by glioma-secreted chemokines can be blocked with chemotherapy. Cancer Immunol Immunother 57:123–131 ArticlePubMedCAS Google Scholar
Kuratsu J, Yoshizato K, Yoshimura T, Leonard EJ, Takeshima H, Ushio Y (1993) Quantitative study of monocyte chemoattractant protein-1 (MCP-1) in cerebrospinal fluid and cyst fluid from patients with malignant glioma. J Natl Cancer Inst 85:9–1836 Article Google Scholar
Platten M, Kretz A, Naumann U et al (2003) Monocyte chemoattractant protein-1 increases microglial infiltration and aggressiveness of gliomas. Ann Neurol 54:388–392 ArticlePubMedCAS Google Scholar
Loberg RD, Ying C, Craig M et al (2007) Targeting CCL2 with systemic delivery of neutralizing antibodies induces prostate cancer tumor regression in vivo. Cancer Res 67:9417–9424 ArticlePubMedCAS Google Scholar
Tsui P, Das A, Whitaker B et al (2007) Generation, characterization and biological activity of CCL2 (MCP-1/JE) and CCL12 (MCP-5) specific antibodies. Hum Antibodies 16:117–125 PubMedCAS Google Scholar
Carton JM, Sauerwald T, Hawley-Nelson P et al (2007) Codon engineering for improved antibody expression in mammalian cells. Protein Expr Purif 55:279–286 ArticlePubMedCAS Google Scholar
Fujita M, Zhu X, Sasaki K et al (2008) Inhibition of STAT3 promotes the efficacy of adoptive transfer therapy using type-1 CTLs by modulation of the immunological microenvironment in a murine intracranial glioma. J Immunol 180:2089–2098 PubMedCAS Google Scholar
Nishimura F, Dusak JE, Eguchi J et al (2006) Adoptive transfer of Type 1 CTL mediates effective anti-central nervous system tumor response: critical roles of IFN-inducible protein-10. Cancer Res 66:4478–4487 ArticlePubMedCAS Google Scholar
Sasaki K, Zhu X, Vasquez C et al (2007) Preferential expression of very late antigen-4 on type 1 CTL cells plays a critical role in trafficking into central nervous system tumors. Cancer Res 67:6451–6458 ArticlePubMedCAS Google Scholar
Zhu X, Nishimura F, Sasaki K et al (2007) Toll like receptor-3 ligand poly-ICLC promotes the efficacy of peripheral vaccinations with tumor antigen-derived peptide epitopes in murine CNS tumor models. J Transl Med 5:10 ArticlePubMed Google Scholar
Zhu X, Fallert-Junecko BA, Fujita M et al (2010) Poly-ICLC promotes the infiltration of effector T cells into intracranial gliomas via induction of CXCL10 in IFN-alpha and IFN-gamma dependent manners. Cancer Immunol Immunother 59:1401–1409 ArticlePubMedCAS Google Scholar
Lewis C, Murdoch C (2005) Macrophage responses to hypoxia: implications for tumor progression and anti-cancer therapies. Am J Pathol 167:627–635 ArticlePubMedCAS Google Scholar
Kaur B, Tan C, Brat DJ, Post DE, Van Meir EG (2004) Genetic and hypoxic regulation of angiogenesis in gliomas. J Neurooncol 70:229–243 ArticlePubMed Google Scholar
Kaur B, Khwaja FW, Severson EA, Matheny SL, Brat DJ, Van Meir EG (2005) Hypoxia and the hypoxia-inducible-factor pathway in glioma growth and angiogenesis. Neuro Oncol 7:134–153 ArticlePubMedCAS Google Scholar
Stupp R, Dietrich PY, Ostermann KS et al (2002) Promising survival for patients with newly diagnosed glioblastoma multiforme treated with concomitant radiation plus temozolomide followed by adjuvant temozolomide. J Clin Oncol 20:1375–1382 ArticlePubMedCAS Google Scholar
Stupp R, Mason WP, van den Bent MJ et al (2005) Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 352:987–996 ArticlePubMedCAS Google Scholar
Ueda R, Fujita M, Zhu X et al (2009) Systemic inhibition of transforming growth factor-beta in glioma-bearing mice improves the therapeutic efficacy of glioma-associated antigen peptide vaccines. Clin Cancer Res 15:6551–6559 ArticlePubMedCAS Google Scholar
Fridlender ZG, Buchlis G, Kapoor V et al (2010) CCL2 blockade augments cancer immunotherapy. Cancer Res 70:109–118 ArticlePubMedCAS Google Scholar
Ford AL, Goodsall AL, Hickey WF, Sedgwick JD (1995) Normal adult ramified microglia separated from other central nervous system macrophages by flow cytometric sorting. Phenotypic differences defined and direct ex vivo antigen presentation to myelin basic protein-reactive CD4 + T cells compared. J Immunol 154:4309–4321 PubMedCAS Google Scholar
Badie B, Schartner J (2001) Role of microglia in glioma biology. Microsc Res Tech 54:106–113 ArticlePubMedCAS Google Scholar
Okada H, Kohanbash G, Zhu X et al (2009) Immunotherapeutic approaches for glioma. Crit Rev Immunol 29:1–42 PubMedCAS Google Scholar
Fujita M, Scheurer ME, Decker SA et al (2010) Role of type 1 IFNs in antiglioma immunosurveillance–using mouse studies to guide examination of novel prognostic markers in humans. Clin Cancer Res 16:3409–3419 ArticlePubMedCAS Google Scholar