An efficient medical image encryption using hybrid DNA computing and chaos in transform domain (original) (raw)
Abstract
In this growing era, a massive amount of digital electronic health records (EHRs) are transferred through the open network. EHRs are at risk of a myriad of security threats, to overcome such threats, encryption is a reliable technique to secure data. This paper addresses an encryption algorithm based on integer wavelet transform (IWT) blended with deoxyribo nucleic acid (DNA) and chaos to secure the digital medical images. The proposed work comprises of two phases, i.e. a two-stage shuffling phase and diffusion phase. The first stage of shuffling starts with initial block confusion followed by row and column shuffling of pixels as the second stage. The pixels of the shuffled image are circularly shifted bitwise at the first stage of diffusion to enhance the security of the system against differential attack. The second stage of diffusion operation is based on DNA coding and DNA XOR operations. The experimental analyses have been carried out with 100 DICOM test images of 16-bit depth to evaluate the strength of the algorithm against statistical and differential attacks. By the results, the maximum entropy has been obtained an average of 15.79, NPCR of 99.99, UACI of 33.31, and larger keyspace of 10140, which infer that our technique overwhelms various other state-of-the-art techniques.
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References
- Aashiq BS, Amirtharajan R (2020) A robust medical image encryption in dual domain: chaos-DNA-IWT combined approach. Med Biol Eng Comput 58:1445–1458. https://doi.org/10.1007/s11517-020-02178-w
Article Google Scholar - Chidambaram N, Raj P, Thenmozhi K, Rajagopalan S, Amirtharajan R (2019) A cloud compatible DNA coded security solution for multimedia file sharing & storage. Multimed Tools Appl 78:33837–33863. https://doi.org/10.1007/s11042-019-08166-z
Article Google Scholar - Arumugham S, Rajagopalan S, Bosco J et al (2018) Networked medical data sharing on secure medium - a web publishing mode for DICOM viewer with three layer authentication. J Biomed Inform 86:90–105. https://doi.org/10.1016/j.jbi.2018.08.010
Article PubMed Google Scholar - Aashiq BS, Amirtharajan R (2020) Bio-inspired cryptosystem on reciprocal domain-DNA strands mutate to secure health data. Front Inform Technol Electron Eng. https://doi.org/10.1631/FITEE.2000071
- Dhall S, Pal SK, Sharma K (2018) Cryptanalysis of image encryption scheme based on a new 1D chaotic system. Signal Process 146:22–32. https://doi.org/10.1016/J.SIGPRO.2017.12.021
Article Google Scholar - Liu J, Ma Y, Li S, Lian J, Zhang X (2018) A new simple chaotic system and its application in medical image encryption. Multimed Tools Appl 77:22787–22808. https://doi.org/10.1007/s11042-017-5534-8
Article Google Scholar - Dzwonkowski M, Rykaczewski R (2019) Secure quaternion feistel cipher for DICOM images. IEEE Trans Image Process 28:371–380. https://doi.org/10.1109/TIP.2018.2868388
Article PubMed Google Scholar - Aashiq Banu S, Amirtharajan R (2020) Tri-level scrambling and enhanced diffusion for DICOM image cipher- DNA and chaotic fused approach. Multimed Tools Appl 79:28807–28824. https://doi.org/10.1007/s11042-020-09501-5
Article Google Scholar - Subashanthini S, Pounambal M (2019) Three stage hybrid encryption of cloud data with penta-layer security for online business users. IseB 18:379–404. https://doi.org/10.1007/s10257-019-00419-6
Article Google Scholar - Dagadu JC, Li J, Aboagye EO (2019) Medical image encryption based on hybrid chaotic dna diffusion. Wirel Pers Commun 108:591–612. https://doi.org/10.1007/s11277-019-06420-z
Article Google Scholar - Mohamed Parvees MY, Abdul Samath J, Parameswaran Bose B (2017) Medical images are safe – an enhanced chaotic scrambling approach. J Med Syst 41. https://doi.org/10.1007/s10916-017-0809-1
- Sun S (2018) A novel hyperchaotic image encryption scheme based on DNA encoding, pixel-level scrambling and bit-level scrambling. IEEE Photon J 10:1–14. https://doi.org/10.1109/JPHOT.2018.2817550
Article Google Scholar - Guan M, Yang X, Hu W (2019) Chaotic image encryption algorithm using frequency-domain DNA encoding. IET Image Process 13:1535–1539. https://doi.org/10.1049/iet-ipr.2019.0051
Article Google Scholar - Shaik A, Thanikaiselvan V (2018) Comparative analysis of integer wavelet transforms in reversible data hiding using threshold based histogram modification. J King Saud Univ Comput Inform Sci. https://doi.org/10.1016/j.jksuci.2018.06.001
- Priya S, Santhi B (2019) A novel visual medical image encryption for secure transmission of authenticated watermarked medical images. Mobile Netw Appl. https://doi.org/10.1007/s11036-019-01213-x
- Suri S, Vijay R (2019) A synchronous intertwining logistic map-DNA approach for color image encryption. J Ambient Intell Humaniz Comput 10:2277–2290. https://doi.org/10.1007/s12652-018-0825-0
Article Google Scholar - Huo D, Fu ZD, Yuan S et al (2019) Image encryption using exclusive-OR with DNA complementary rules and double random phase encoding. Physics Lett Sect A Gen Atom Solid State Phys 383:915–922. https://doi.org/10.1016/j.physleta.2018.12.011
Article CAS Google Scholar - Li Y, Ge G (2019) Cryptographic and parallel hash function based on cross coupled map lattices suitable for multimedia communication security. Multimed Tools Appl 78:17973–17994. https://doi.org/10.1007/s11042-018-7122-y
Article Google Scholar - Praveenkumar P, Kerthana Devi N, Ravichandran D, Avila J, Thenmozhi K, Rayappan JBB, Amirtharajan R (2018) Transreceiving of encrypted medical image – a cognitive approach. Multimed Tools Appl 77:8393–8418. https://doi.org/10.1007/s11042-017-4741-7
Article Google Scholar - Ravichandran D, Rajagopalan S, Upadhyay HN, Rayappan JBB, Amirtharajan R (2019) Encrypted biography of biomedical image - a pentalayer cryptosystem on FPGA. J Signal Process Syst 91:475–501. https://doi.org/10.1007/s11265-018-1337-z
Article Google Scholar - Ravichandran D, Praveenkumar P, Rayappan JBB, Amirtharajan R (2017) DNA chaos blend to secure medical privacy. IEEE Trans Nanobiosci 16:850–858. https://doi.org/10.1109/TNB.2017.2780881
Article Google Scholar - Kumar S, Panna B, Jha RK (2019) Medical image encryption using fractional discrete cosine transform with chaotic function. Med Biol Eng Comput 57:2517–2533. https://doi.org/10.1007/s11517-019-02037-3
Article PubMed Google Scholar - Aqeel-ur-Rehman LX, Hahsmi MA, Haider R (2018) An efficient mixed inter-intra pixels substitution at 2bits-level for image encryption technique using DNA and chaos. Optik 153:117–134. https://doi.org/10.1016/j.ijleo.2017.09.099
Article CAS Google Scholar - Hua Z, Yi S, Zhou Y (2018) Medical image encryption using high-speed scrambling and pixel adaptive diffusion. Signal Process 144:134–144. https://doi.org/10.1016/j.sigpro.2017.10.004
Article Google Scholar - Belazi A, Talha M, Kharbech S, Xiang W (2019) Novel medical image encryption scheme based on chaos and DNA encoding. IEEE Access 7:36667–36681. https://doi.org/10.1109/ACCESS.2019.2906292
Article Google Scholar - Chai X, Gan Z, Yuan K, Chen Y, Liu X (2019) A novel image encryption scheme based on DNA sequence operations and chaotic systems. Neural Comput & Applic 31:219–237. https://doi.org/10.1007/s00521-017-2993-9
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Acknowledgements
Authors wish to thank the Intrusion Detection Lab at School of Electrical & Electronics Engineering, SASTRA Deemed University, for providing infrastructural support to carry out this research work.
Funding
The authors wish to express their sincere thanks to the INSPIRE Fellowship (No. DST/INSPIRE Fellowship/2015/IF150628), Department of Science and Technology (DST), India, for their financial support and FIST funding (SR/FST/ET-II/2018/221).
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Authors and Affiliations
- School of Electrical & Electronics Engineering, SASTRA Deemed University, Thanjavur, 613 401, India
Dhivya Ravichandran, Aashiq Banu S, Vidhyadharini Balasubramanian & Rengarajan Amirtharajan - Ministry of Electronics and IT, New Delhi, India
B.K Murthy - Infosys Limited, Mysore, Karnataka, 570027, India
Sherin Fathima
Authors
- Dhivya Ravichandran
- Aashiq Banu S
- B.K Murthy
- Vidhyadharini Balasubramanian
- Sherin Fathima
- Rengarajan Amirtharajan
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Correspondence toRengarajan Amirtharajan.
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Ravichandran, D., Banu S, A., Murthy, B. et al. An efficient medical image encryption using hybrid DNA computing and chaos in transform domain.Med Biol Eng Comput 59, 589–605 (2021). https://doi.org/10.1007/s11517-021-02328-8
- Received: 03 July 2020
- Accepted: 24 January 2021
- Published: 09 February 2021
- Version of record: 09 February 2021
- Issue date: March 2021
- DOI: https://doi.org/10.1007/s11517-021-02328-8