Brain Uptake and Utilization of Fatty Acids, Lipids and Lipoproteins: Application to Neurological Disorders (original) (raw)
References
Abumrad, N. A., el-Maghrabi, M. R., Amri, E. Z., Lopez, E., & Grimaldi, P. A. (1993). Cloning of a rat adipocyte membrane protein implicated in binding or transport of long-chain fatty acids that is induced during preadipocyte differentiation. Homology with human CD36. Journal of Biological Chemistry, 268, 17665–17668. PubMedCAS Google Scholar
Alkayed, N. J., Goyagi, T., Joh, H. D., Klaus, J., Harder, D. R., Traystman, R. J., et al. (2002). Neuroprotection and P450 2C11 upregulation after experimental transient ischemic attack. Stroke, 33, 1677–1684. ArticlePubMedCAS Google Scholar
Andreasson, K. I., Savonenko, A., Vidensky, S., Goellner, J. J., Zhang, Y., Shaffer, A., et al. (2001). Age-dependent cognitive deficits and neuronal apoptosis in cyclooxygenase-2 transgenic mice. Journal of Neuroscience, 21, 8198–8209. PubMedCAS Google Scholar
Arlt, S., Beisiegel, U., & Kontush, A. (2002). Lipid peroxidation in neurodegeneration: new insights into Alzheimer’s disease. Current Opinion in Lipidology, 13, 289–294. ArticlePubMedCAS Google Scholar
Bazan, N. G., Colangelo, V., & Lukiw, W. J. (2002). Prostaglandins and other lipid mediators in Alzheimer’s disease. Prostaglandins & Other Lipid Mediators, 68–69, 197–210. Article Google Scholar
Beffert, U., Stolt, P. C., & Herz, J. (2004). Functions of lipoprotein receptors in neurons. Journal of Lipid Research, 45, 403–409. ArticlePubMedCAS Google Scholar
Beisiegel, U., & Spector, A. A. (2001). Lipids and lipoproteins in the brain. Current Opinion in Lipidology, 12, 243–244. ArticlePubMedCAS Google Scholar
Coe, N. R., Smith, A. J., Frohnert, B. I., Watkins, P. A., & Bernlohr, D. A. (1999). The fatty acid transport protein (FATP1) is a very long chain acyl-CoA synthetase. Journal of Biological Chemistry, 274, 36300–36304. ArticlePubMedCAS Google Scholar
Cunnane, S. C., Williams, S. C., Bell, J. D., Brookes, S., Craig, K., Iles, R. A., et al. (1994). Utilization of uniformly labeled 13C-polyunsaturated fatty acids in the synthesis of long-chain fatty acids and cholesterol accumulating in the neonatal rat brain. Journal of Neurochemistry, 62, 2429–2436. ArticlePubMedCAS Google Scholar
Edmond, J., Higa, T. A., Korsak, R. A., Bergner, E. A., & Lee, W. -N. P. (1998). Fatty acid transport and utilization for the developing brain. Journal of Neurochemistry, 70, 1227–1234. ArticlePubMedCAS Google Scholar
Fam, S. S., & Morrow, J. D. (2003). The isoprostanes: Unique products of arachidonic acid oxidation—a review. Current Medicinal Chemistry, 10, 1723–1740. ArticlePubMedCAS Google Scholar
Fam, S. S., Murphey, L. J., Terry, E. S., Zackert, W. E., Chen, Y., & Gao, L., et al. (2002). Formation of highly reactive A-ring and J-ring isoprostane-like compounds (A4/J4-neuroprostanes) in vivo from docosahexaenoic acid. Journal of Biological Chemistry, 277, 36076–36084. ArticlePubMedCAS Google Scholar
Febbraio, M., Guy, E., Coburn, C., Knapp, F. F., Jr., Beets, A. L., Abumrad N. A., et al. (2002). The impact of overexpression and deficiency of fatty acid translocase (FAT)/CD36. Molecular and Cellular Biochemistry, 239, 193–197. ArticlePubMedCAS Google Scholar
Fegley, D., Kathuria, S., Mercier, R., Li, C., Goutopoulos, A., & Makriyannis, A., et al. (2004). Anandamide transport is independent of fatty-acid amide hydrolase activity and is blocked by the hydrolysis-resistant inhibitor AM1172. Proceedings of the National Academy of Sciences of the United States of America, 101, 8756–8761. ArticlePubMedCAS Google Scholar
Fischer, H., Gottschlich, R., & Seelig, A. (1998). Blood–brain barrier permeation: Molecular parameters governing passive diffusion. Journal of Membrane Biology, 165, 201–211. ArticlePubMedCAS Google Scholar
Freed, L. M., Wakabayashi, S., Bell, J. M., & Rapoport, S. I. (1994). Effect of inhibition of beta-oxidation on incorporation of [U- 14C]palmitate and [1-14C]arachidonate into brain lipids. Brain Research, 645, 41–48. ArticlePubMedCAS Google Scholar
Gerdeman, G. L., Partridge, J. G., Lupica, C. R., & Lovinger, D. M. (2003). It could be habit forming: Drugs of abuse and striatal synaptic plasticity. Trends Neurosci, 26, 184–192. ArticlePubMedCAS Google Scholar
Glaser, S. T., Abumrad, N. A., Fatade, F., Kaczocha, M., Studholme, K. M., & Deutsch, D. G. (2003). Evidence against the presence of an anandamide transporter. Proceedings of the National Academy of Sciences of the United States of America, 100, 4269–4274. ArticlePubMedCAS Google Scholar
Guo, W., Huang, N., Cai, J., Xie, W., & Hamilton, J. A. (2006). Fatty acid transport and metabolism in HepG2 cells. American Journal of Physiology: Gastrointestinal and Liver Physiology, 290, G528–G534. ArticlePubMedCAS Google Scholar
Hamilton, J. A., Guo, W., & Kamp, F. (2002). Mechanism of cellular uptake of long-chain fatty acids: Do we need cellular proteins? Molecular and Cellular Biochemistry, 239, 17–23. ArticlePubMedCAS Google Scholar
Herrmann, T., Buchkremer, F., Gosch, I., Hall, A. M., Bernlohr, D. A., & Stremmel, W. (2001). Mouse fatty acid transport protein 4 (FATP4): Characterization of the gene and functional assessment as a very long chain acyl-CoA synthetase. Gene, 270, 31–40. ArticlePubMedCAS Google Scholar
Herz, J. (2003). LRP: A bright beacon at the blood–brain barrier. Journal of Clinical Investigation, 112, 1483–1485. ArticlePubMedCAS Google Scholar
Hillard, C. J. (2000). Biochemistry and pharmacology of the endocannabinoids arachidonylethanolamide and 2-arachidonylglycerol. Prostaglandins & Other Lipid Mediators, 61, 3–18. ArticleCAS Google Scholar
Hillard, C. J., & Jarrahian, A. (2000). The movement of N-arachidonoylethanolamine (anandamide) across cellular membranes. Chemistry and Physics of Lipids, 108, 123–134. ArticlePubMedCAS Google Scholar
Hui, T. Y., & Bernlohr, D. A. (1997). Fatty acid transporters in animal cells. Frontiers in Bioscience, 2, 222–231. Google Scholar
Kamp, F., Hamilton, J. A., & Westerhoff, H. V. (1993). Movement of fatty acids, fatty acid analogues, and bile acids across phospholipid bilayers. Biochemistry, 32, 11074–11086. ArticlePubMedCAS Google Scholar
Kamp, F., Zakim, D., Zhang, F., Noy, N., & Hamilton, J. A. (1995). Fatty acid flip-flop in phospholipid bilayers is extremely fast. Biochemistry, 34, 11928–11937. ArticlePubMedCAS Google Scholar
Kamp, F., Guo, W., Souto, R., Pilch, P. F., Corkey, B. E., & Hamilton, J. A. (2003). Rapid flip-flop of oleic acid across the plasma membrane of adipocytes. Journal of Biological Chemistry, 7988–7995.
Kehl, F., Cambj-Sapunar, L., Maier, K. G., Miyata, N., Kametani, S., Okamoto, H., et al. (2002). 20-HETE contributes to the acute fall in cerebral blood flow after subarachnoid hemorrhage in the rat. American Journal of Physiology Heart and Circulatory Physiology, 282, H1556–1565. PubMedCAS Google Scholar
Kliewer, S. A., Sundseth, S. S., Jones, S. A., Brown, P. J., Wisely, G. B., Koble, C. S., et al. (1997). Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma. Proceedings of the National Academy of Sciences of the United States of America, 94, 4318–4323. ArticlePubMedCAS Google Scholar
Mahley, R. W., & Huang, Y. (1999). Apolipoprotein E: From atherosclerosis to Alzheimer’s disease and beyond. Current Opinion in Lipidology, 10, 207–217. ArticlePubMedCAS Google Scholar
Martinez, M. (1992). Abnormal profiles of polyunsaturated fatty acids in the brain, liver, kidney and retina of patients with peroxisomal disorders. Brain Research, 583, 171–182. ArticlePubMedCAS Google Scholar
Martinez, M., Mougan, I. Roig, M., & Ballabriga, A. (1994). Blood polyunsaturated fatty acids in patients with peroxisomal disorders—A multicenter study. Lipids, 29, 273–280. ArticlePubMedCAS Google Scholar
Martinez, M. (1996). Docosahexaenoic acid therapy in docosahexaenoic acid-deficient patients with disorders of peroxisomal biogenesis. Lipids, 31, S145–S152. ArticlePubMedCAS Google Scholar
Martinez, M., & Vazquez, E. (1998). MRI evidence that docosahexaenoic acid ethyl ester improves myelination in generalized peroxisomal disorders. Neurology, 51, 26–32. PubMedCAS Google Scholar
Montine, T. J., Milatovic, D., Gupta, R. C., Valyi-Nagy, T., Morrow, J. D., & Breyer, R. M. (2002a). Neuronal oxidative damage from activated innate immunity is EP2 receptor-dependent. Journal of Neurochemistry, 83, 463–470. ArticlePubMedCAS Google Scholar
Montine, T. J., Neely, M. D., Quinn, J. F., Beal, M. F., Markesbery, W. R., Roberts, L. J., et al. (2002b). Lipid peroxidation in aging brain and Alzheimer’s disease. Free Radical Biology & Medicine, 33, 620–626. ArticleCAS Google Scholar
Morell, P., & Toews, A. D. (1996). Biochemistry of Lipids. In Moser, H. W. (Ed.), Handbook of Clinical Neurology, Vol. 22 (66): Neurodystrophies and Neurolipidoses (pp. 33–49). Amsterdam: Elsevier. Google Scholar
Morris, M. C., Evans, D. A., Bienias, J. L., Tangney, C. C., Bennett, D. A., Wilson, R. S., et al. (2003). Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease. Archives of Neurology, 60, 940–946. ArticlePubMed Google Scholar
Moser, H. W. (1997). Adrenoleukodystrophy: Phenotype, genetics, pathogenesis and therapy. Brain, 120, 1485–1508. ArticlePubMed Google Scholar
Moser, H. W., Raymond, G. V., Koehler, W., Sokolowski, P., Hanefeld, F., & Korenke, G. C., et al. (2003). Evaluation of the preventive effect of glyceryl trioleate-trierucate (“Lorenzo’s oil”) therapy in X-linked adrenoleukodystrophy: Results of two concurrent trials. Advances in Experimental Medicine and Biology, 544, 369–387. PubMedCAS Google Scholar
Mostofsky, D. I., Yehuda, S., & Salem, N., Jr. (2001). Fatty acids: Physiological and behavioral functions. Totowa, NJ: Humana Press, Nutrition and Health. Google Scholar
Noronha, J. G., Bell, J. M., & Rapoport, S. I. (1990). Quantitative brain autoradiography of [9,10-3H]palmitic acid incorporation into brain lipids. Journal of Neuroscience Research, 26, 196–208. ArticlePubMedCAS Google Scholar
Pawlosky, R. J., Ward, G., & Salem, N., Jr. (1996). Essential fatty acid uptake and metabolism in the developing rodent brain. Lipids, 31(Suppl), S103–S107. ArticlePubMedCAS Google Scholar
Petroni, A., Bertagnolio, B., La Spada, P., Blasevich, M., Papini, N., & Govoni, S., et al. (1998). The beta-oxidation of arachidonic acid and the synthesis of docosahexaenoic acid are selectively and consistently altered in skin fibroblasts from three Zellweger patients versus X-adrenoleukodystrophy, Alzheimer and control subjects. Neuroscience Letters, 250, 145–148. ArticlePubMedCAS Google Scholar
Purdon, D., Arai, T., & Rapoport, S. (1997). No evidence for direct incorporation of esterified palmitic acid from plasma into brain lipids of awake adult rat. Journal of Lipid Research, 38, 526–530. PubMedCAS Google Scholar
Rapoport, S. I. (2001). In vivo fatty acid incorporation into brain phosholipids in relation to plasma availability, signal transduction and membrane remodeling. Journal of Molecular Neuroscience, 16, 243–261; discussion 279–284. ArticlePubMedCAS Google Scholar
Rapoport, S. I., Chang, M. C., & Spector, A. A. (2001). Delivery and turnover of plasma-derived essential PUFAs in mammalian brain. Journal of Lipid Research, 42, 678–685. PubMedCAS Google Scholar
Schaffer, J. E., & Lodish, H. F. (1994). Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein. Cell, 79, 427–436. ArticlePubMedCAS Google Scholar
Soderberg, M., Edlund, C., Kristensson, K., & Dallner, G. (1991). Fatty acid composition of brain phospholipids in aging and in Alzheimer’s disease. Lipids, 26, 421–425. ArticlePubMedCAS Google Scholar
Sprecher, H., Luthria, D. L., Mohammed, B. S., & Baykousheva, S. P. (1995). Reevaluation of the pathways for the biosynthesis of polyunsaturated fatty acids. Journal of Lipid Research, 36, 2471–2477. PubMedCAS Google Scholar
Sprecher, H., Chen, Q., & Yin, F. Q. (1999). Regulation of the biosynthesis of 22:5n-6 and 22:6n-3: A complex intracellular process. Lipids, 34, S153–156. ArticlePubMedCAS Google Scholar
Stahl, A. (2004). A current review of fatty acid transport proteins (SLC27). PfluÉgers Archiv, 447, 722–727. ArticlePubMedCAS Google Scholar
Steinberg, S. J., Wang, S. J., Kim, D. G., Mihalik, S. J., & Watkins, P. A. (1999a). Human very-long-chain acyl-CoA synthetase: cloning, topography, and relevance to branched-chain fatty acid metabolism. Biochemical and Biophysical Research Communications, 257, 615–621. ArticlePubMedCAS Google Scholar
Steinberg, S. J., Wang, S. J., McGuinness, M. C., & Watkins, P. A. (1999b). Human liver-specific very-long-chain acyl-coenzyme A synthetase: cDNA cloning and characterization of a second enzymatically active protein. Molecular Genetics and Metabolism, 68, 32–42. ArticlePubMedCAS Google Scholar
Stremmel, W., Strohmeyer, G., Borchard, F., Shaul, K., & Berk, P.D. (1985). Isolation and partial characterization of a fatty acid binding protein in rat liver plasma membrane. Proceedings of the National Academy of Sciences of the United States of America, 82, 4–8. ArticlePubMedCAS Google Scholar
Terracina, L., Brunetti, M., Avellini, L., De Medio, G.E., Trovarelli, G., & Gaiti, A. (1992). Arachidonic and palmitic acid utilization in aged rat brain areas. Molecular and Cellular Biochemistry, 115, 35–42. ArticlePubMedCAS Google Scholar
Theda, C., Moser, A. B., Powers, J. M., & Moser, H. W. (1992). Phospholipids in X-linked adrenoleukodystrophy white matter—Fatty acid abnormalities before the onset of demyelination. Journal of the Neurological Sciences, 110, 195–204. ArticlePubMedCAS Google Scholar
Urano, S., Sato, Y., Otonari, T., Makabe, S., Suzuki, S., Ogata, M., et al. (1998). Aging and oxidative stress in neurodegeneration. Biofactors, 7, 103–112. PubMedCAS Google Scholar
Vidensky, S., Zhang, Y., Hand, T., Goellner, J., Shaffer, A., Isakson, P., et al. (2003). Neuronal overexpression of COX-2 results in dominant production of PGE2 and altered fever response. Neuromolecular Med, 3, 15–28. ArticlePubMedCAS Google Scholar
Watkins, P. A., Hamilton, J. A., Leaf, A., Spector, A. A., Moore, S. A., Anderson, R. E., et al. (2001). Brain uptake and utilization of fatty acids: applications to peroxisomal biogenesis diseases. Journal of Molecular Neuroscience, 16, 87–92 (discussion 151–157). ArticlePubMedCAS Google Scholar
Yepes, M., Sandkvist, M., Moore, E. G., Bugge, T. H., Strickland, D. K., & Lawrence, D. A. (2003). Tissue-type plasminogen activator induces opening of the blood–brain barrier via the LDL receptor-related protein. Journal of Clinical Investigation, 112, 1533–15340. ArticlePubMedCAS Google Scholar
Zhang, C., & Harder, D. R. (2002). Cerebral capillary endothelial cell mitogenesis and morphogenesis induced by astrocytic epoxyeicosatrienoic Acid. Stroke, 33, 2957–2964. ArticlePubMedCAS Google Scholar