MicroRNA Expression Analysis of Human Pulmonary Fibroblasts Treated with Acrolein (original) (raw)

• Strieter, R.M. & Mehrad, B. New mechanisms of pulmonary fibrosis. Chest 136, 1364–1370 (2009).
  Article PubMed PubMed Central Google Scholar
• Sun, Q. et al. PRMT1 Upregulated by Epithelial Proinflammatory Cytokines Participates in COX2 Expression in Fibroblasts and Chronic Antigen-Induced Pulmonary Inflammation. J. Immunol. 195, 298–306 (2015).
  Article CAS PubMed Google Scholar
• Kim, G.D. et al. Melatonin suppresses acrolein-induced IL-8 production in human pulmonary fibroblasts. J. Pineal. Res. 52, 356–364 (2012).
  Article CAS PubMed Google Scholar
• Murugan, V. & Peck, M.J. Signal transduction pathways linking the activation of alveolar macrophages with the recruitment of neutrophils to lungs in chronic obstructive pulmonary disease. Exp. Lung Res. 35, 439–485 (2009).
  Article CAS PubMed Google Scholar
• Togo, S. et al. Lung fibroblast repair functions in patients with chronic obstructive pulmonary disease are altered by multiple mechanisms. Am. J. Respir. Crit. Care Med. 178, 248–260 (2008).
  Article CAS PubMed PubMed Central Google Scholar
• Cho, Y. et al. Analysis of Dose-Response to Hexanal-Induced Gene Expression in A549 Human Alveolar Cells. BioChip J. 8, 75–82 (2014).
  Article CAS Google Scholar
• Barnes, P.J. Inflammatory mechanisms in patients with chronic obstructive pulmonary disease. J. Allergy Clin. Immunol. 138, 16–27 (2016).
  Article CAS PubMed Google Scholar
• Moretto, N. et al. alpha,beta-Unsaturated aldehydes contained in cigarette smoke elicit IL-8 release in pulmonary cells through mitogen-activated protein kinases. Am. J. Physiol. Lung Cell. Mol. Physiol. 296, L839–L848 (2009).
  Article CAS PubMed Google Scholar
• Kim, W.J. et al. Altered miRNA expression in lung tissues of patients with chronic obstructive pulmonary disease. Mol. Cell. Toxicol. 13, 207–212 (2017).
  Article CAS Google Scholar
• D’Anna, C. et al. Cigarette smoke alters cell cycle and induces inflammation in lung fibroblasts. Life Sci. 126, 10–18 (2015).
  Article CAS PubMed Google Scholar
• Volpi, G. et al. Cigarette smoke and alpha,beta-unsaturated aldehydes elicit VEGF release through the p38 MAPK pathway in human airway smooth muscle cells and lung fibroblasts. Br. J. Pharmacol. 163, 649–661 (2011).
  Article CAS PubMed PubMed Central Google Scholar
• Jang, J.H. et al. Acrolein-exposed normal human lung fibroblasts in vitro: cellular senescence, enhanced telomere erosion, and degradation of werner’s syndrome protein. Environ. Health Perspect. 122, 955–962 (2014).
  Article CAS PubMed PubMed Central Google Scholar
• Lee, S. et al. Effect of crotonaldehyde on the induction of HO-1 expression in A549 cells. Mol. Cell. Toxicol. 13, 221–227 (2017).
  Article CAS Google Scholar
• Marnett, L.J., Riggins, J.N. & West, J.D. Endogenous generation of reactive oxidants and electrophiles and their reactions with DNA and protein. J. Clin. Invest. 111, 583–593 (2003).
  Article CAS PubMed PubMed Central Google Scholar
• Lee, S.E. & Park, Y.S. Role of lipid peroxidationderived alpha, beta-unsaturated aldehydes in vascular dysfunction. Oxid. Med. Cell. Longev. 2013, 629028 (2013).
  PubMed PubMed Central Google Scholar
• Randall, M.J. et al. Acrolein-induced activation of mitogen-activated protein kinase signaling is mediated by alkylation of thioredoxin reductase and thioredoxin 1. Redox Biol. 1, 265–275 (2013).
  Article CAS PubMed PubMed Central Google Scholar
• Kozekov, I.D. et al. DNA interchain cross-links formed by acrolein and crotonaldehyde. J. Am. Chem. Soc. 125, 50–61 (2003).
  Article CAS PubMed Google Scholar
• Cai, J., Bhatnagar, A. & Pierce, Jr., W.M. Protein modification by acrolein: formation and stability of cysteine adducts. Chem. Res. Toxicol. 22, 708–716 (2009).
  Article CAS PubMed PubMed Central Google Scholar
• Oruqaj, G. et al. Compromised peroxisomes in idiopathic pulmonary fibrosis, a vicious cycle inducing a higher fibrotic response via TGF-beta signaling. Proc. Natl. Acad. Sci. U S A 112, E2048–E2057 (2015).
  Article CAS PubMed PubMed Central Google Scholar
• Kehrer, J.P. & Biswal, S.S. The molecular effects of acrolein. Toxicol. Sci. 57, 6–15 (2000).
  Article CAS PubMed Google Scholar
• Carnevali, S. et al. Clusterin decreases oxidative stress in lung fibroblasts exposed to cigarette smoke. Am. J. Respir. Crit. Care Med. 174, 393–399 (2006).
  Article CAS PubMed Google Scholar
• Hoshino, Y. et al. Cytotoxic effects of cigarette smoke extract on an alveolar type II cell-derived cell line. Am. J. Physiol. Lung Cell Mol. Physiol. 281, L509–L516 (2001).
  Article CAS PubMed Google Scholar
• Bengestrate, L. et al. Genome-wide profiling of microRNAs in adipose mesenchymal stem cell differentiation and mouse models of obesity. PLoS One 6, e21305 (2011).
  Article CAS PubMed PubMed Central Google Scholar
• Lim, J.H. et al. Expression of exosomal and cellular microRNAs: as biomarkers for toluene, ethylbenzene, xylene (TEX) exposure. Mol. Cell. Toxicol. 12, 359–369 (2016).
  Article CAS Google Scholar
• Paul, S. et al. Impact of miRNA deregulation on mRNA expression profiles in response to environmental toxicant, nonylphenol. Mol. Cell. Toxicol. 7, 259–269 (2011).
  Article CAS Google Scholar
• Fish, J.E. A primer on the role of microRNAs in endothelial biology and vascular disease. Semin. Nephrol. 32, 167–175 (2012).
  Article CAS PubMed Google Scholar
• Yu, B. et al. Profile of microRNAs following rat sciatic nerve injury by deep sequencing: implication for mechanisms of nerve regeneration. PLoS One 6, e24612 (2011).
  Article CAS PubMed PubMed Central Google Scholar
• Zhang, Y.Q. et al. Expression profiling and pathway analysis of microRNA expression in the lungs of mice exposed to long-term, low-dose benzo(a)pyrene. Mol. Cell. Toxicol. 10, 67–74 (2014).
  Article CAS Google Scholar
• Lema, C. & Cunningham, M.J. MicroRNAs and their implications in toxicological research. Toxicol. Lett. 198, 100–105 (2010).
  Article CAS PubMed Google Scholar
• Lee, W. et al. Expression profiling of microRNAs in lipopolysaccharide-induced acute lung injury after hypothermia treatment. Mol. Cell. Toxicol. 12, 243–253 (2016).
  Article CAS Google Scholar
• Nana-Sinkam, S.P. et al. Integrating the MicroRNome into the Study of Lung Disease. Am. J. Respir. Crit. Care Med. 179, 4–10 (2009).
  Article CAS PubMed Google Scholar
• Ezzie, M.E. et al. Gene expression networks in COPD: microRNA and mRNA regulation. Thorax 67, 122–131 (2012).
  Article PubMed Google Scholar
• Molina-Pinelo, S. et al. MicroRNA clusters: dysregulation in lung adenocarcinoma and COPD. Eur. Respir. J. 43, 1740–1749 (2014).
  Article CAS PubMed Google Scholar
• Kim, S.H., Turnbull, J. & Guimond, S. Extracellular matrix and cell signalling: the dynamic cooperation of integrin, proteoglycan and growth factor receptor. J. Endocrinol. 209, 139–151 (2011).
  Article CAS PubMed Google Scholar
• Kerrisk, M.E., Cingolani, L.A. & Koleske, A.J. ECM receptors in neuronal structure, synaptic plasticity, and behavior. Prog. Brain Res. 214, 101–131 (2014).
  Article PubMed PubMed Central Google Scholar
• Baglole, C.J., Sime, P.J. & Phipps, R.P. Cigarette smoke-induced expression of heme oxygenase-1 in human lung fibroblasts is regulated by intracellular glutathione. Am. J. Physiol. Lung Cell. Mol. Physiol. 295, L624-L636 (2008).
  Google Scholar
• Rennard, S.I., Togo, S. & Holz, O. Cigarette smoke inhibits alveolar repair: a mechanism for the development of emphysema. Proc. Am. Thorac. Soc. 3, 703–708 (2006).
  Article CAS PubMed PubMed Central Google Scholar
• Park, H.R. et al. Profiling of gene expression using microarray in acrolein-treated human pulmonary fibroblasts. Mol. Cell. Toxicol. 13, 49–58 (2017).
  Article CAS Google Scholar
• Cao, Z. et al. Induction of cellular glutathione and glutathione S-transferase by 3H-1,2-dithiole-3-thione in rat aortic smooth muscle A10 cells: protection against acrolein-induced toxicity. Atherosclerosis 166, 291–301 (2003).
  Article CAS PubMed Google Scholar
• Aldini, G., Orioli, M. & Carini, M. Protein modification by acrolein: relevance to pathological conditions and inhibition by aldehyde sequestering agents. Mol. Nutr. Food Res. 55, 1301–1319 (2011).
  Article CAS PubMed Google Scholar
• Ness, S.A. Microarray analysis: basic strategies for successful experiments. Mol. Biotechnol. 36, 205–219 (2007).
  Article CAS PubMed Google Scholar
• Ness, S.A. Basic microarray analysis: strategies for successful experiments. Methods Mol. Biol. 316, 13–33 (2006).
  PubMed Google Scholar
• Mirnics, K. & Pevsner, J. Progress in the use of microarray technology to study the neurobiology of disease. Nature Neuroscience 7, 434–439 (2004).
  Article CAS PubMed Google Scholar
• Son, G.W. et al. Analysis of miRNA expression profiling in melatonin-exposured endothelial cells. Mol. Cell. Toxicol. 12, 73–81 (2016).
  Article CAS Google Scholar
• Oyadomari, S. & Mori, M. Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ. 11, 381–389 (2004).
  Article CAS PubMed Google Scholar
• Kim, J. et al. Cadmium-induced ER stress and inflammation are mediated through C/EBP-DDIT3 signaling in human bronchial epithelial cells. Exp. Mol. Med. 49, e372 (2017).
  Article CAS PubMed PubMed Central Google Scholar
• Zarcone, M.C. et al. Diesel exhaust alters the response of cultured primary bronchial epithelial cells from patients with chronic obstructive pulmonary disease (COPD) to non-typeable Haemophilus influenzae. Respir. Res. 18, 27 (2017).
  Article CAS PubMed PubMed Central Google Scholar
• Baines, K.J. et al. Novel immune genes associated with excessive inflammatory and antiviral responses to rhinovirus in COPD. Respir. Res. 14, 15–27 (2013).
  Article CAS PubMed PubMed Central Google Scholar
• Takacs, L. Parallel biology: A systematic approach to drug target and biomarker discovery for chronic obstructive pulmonary disease. Tissue Antigens 64, 487–496 (2004).
  Google Scholar
• Wu, Y.P. et al. Activating Transcription Factor 3 Is Essential for Cigarette Smoke-Induced Mucin Expression via Interaction with Activator Protein-1. Am. J. Pathol. 187, 280–291 (2017).
  Article CAS PubMed Google Scholar
• Wu, Y.P. et al. Activating transcription factor 3 represses cigarette smoke-induced IL6 and IL8 expression via suppressing NF-kappaB activation. Toxicol. Lett. 270, 17–24 (2017).
  Article CAS PubMed Google Scholar
• Belvisi, M.G. & Mitchell, J.A. Targeting PPAR receptors in the airway for the treatment of inflammatory lung disease. Br. J. Pharmacol. 158, 994–1003 (2009).
  Article CAS PubMed PubMed Central Google Scholar
• Remels, A.H. et al. Peroxisome proliferator-activated receptors: a therapeutic target in COPD? Eur. Respir. J. 31, 502–508 (2008).
  Article CAS Google Scholar
• van de Garde, M.D. et al. Chronic exposure to glucocorticoids shapes gene expression and modulates innate and adaptive activation pathways in macrophages with distinct changes in leukocyte attraction. J. Immunol. 192, 1196–1208 (2017).
  Article CAS Google Scholar
• Becker, J. et al. Regulation of inflammation by PPARs: a future approach to treat lung inflammatory diseases? Fundam. Clin. Pharmacol. 20, 429–447 (2006).
  Article CAS PubMed Google Scholar