Pulmonary toxocariasis: a case report and literature review (original) (raw)

Abstract

Toxocariasis is a parasitic disease caused by Toxocara canis or T. cati. We report a patient with toxocariasis who presented with dyspnea, high-grade eosinophilia, and bilateral pulmonary nodules. To further characterize the pulmonary manifestations of toxocariasis, we have reviewed 11 previously published pulmonary toxocariasis cases. The most common pulmonary symptoms in our review were cough and dyspnea, and the most common finding on chest imaging was bilateral pulmonary nodules. Risk factors for Toxocara infection primarily included exposure to dogs. Most patients received albendazole and responded well. A high index of suspicion is needed to diagnose this otherwise preventable parasitic disease.

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References

  1. Lassmann B, Tsigrelis C, Virk A. 33-year-old woman with marked eosinophilia. Mayo Clin Proc. 2007;82:103–6.
    Article PubMed Google Scholar
  2. Demirci M, Unlü M, Fidan F, Kaya S. Eosinophilic pneumonia due to toxocariasis: an adult case report. Turkiye Parazitol Derg. 2012;36:258–9.
    Article PubMed Google Scholar
  3. Morimatsu Y, Akao N, Akiyoshi H, Kawazu T, Okabe Y, Aizawa H. A familial case of visceral larva migrans after ingestion of raw chicken livers: appearance of specific antibody in bronchoalveolar lavage fluid of the patients. Am J Trop Med Hyg. 2006;75:303–6.
    PubMed Google Scholar
  4. Sakai S, Shida Y, Takahashi N, Yabuuchi H, Soeda H, Okafuji T, Hatakenaka M, Honda H. Pulmonary lesions associated with visceral larva migrans due to Ascaris suum or Toxocara canis: imaging of six cases. AJR Am J Roentgenol. 2006;186:1697–702.
    Article PubMed Google Scholar
  5. Povazan D, Djurić M, Uzurov-Dinić V, Lalosević D, Lalosević V, Secen S, Povazan A. Adult human case of toxocariasis with pulmonary migratory infiltrate and eosinophilia. Vojnosanit Pregl. 2011;68:881–5.
    Article PubMed Google Scholar
  6. Haralambidou S, Vlachaki E, Ioannidou E, Milioni V, Haralambidis S, Klonizakis I. Pulmonary and myocardial manifestations due to Toxocara canis infection. Eur J Intern Med. 2005;16:601–2.
    Article CAS PubMed Google Scholar
  7. Inoue K, Inoue Y, Arai T, Nawa Y, Kashiwa Y, Yamamoto S, Sakatani M. Chronic eosinophilic pneumonia due to visceral larva migrans. Intern Med. 2002;41:478–82.
    Article PubMed Google Scholar
  8. Aragane K, Akao N, Matsuyama T, Sugita M, Natsuaki M, Kitada O. Fever, cough, and nodules on ankles. Lancet. 1999;354:1872.
    Article CAS PubMed Google Scholar
  9. Sane AC, Barber BA. Pulmonary nodules due to Toxocara canis infection in an immunocompetent adult. South Med J. 1997;90:78–9.
    Article CAS PubMed Google Scholar
  10. Feldman GJ, Parker HW. Visceral larva migrans associated with the hypereosinophilic syndrome and the onset of severe asthma. Ann Intern Med. 1992;116:838–40.
    Article CAS PubMed Google Scholar
  11. Roig J, Romeu J, Riera C, Texido A, Domingo C, Morera J. Acute eosinophilic pneumonia due to toxocariasis with bronchoalveolar lavage findings. Chest. 1992;102:294–6.
    Article CAS PubMed Google Scholar
  12. Jeanfaivre T, Cimon B, Tolstuchow N, de Gentile L, Chabasse D, Tuchais E. Pleural effusion and toxocariasis. Thorax. 1996;51:106–7.
    Article CAS PubMed Central PubMed Google Scholar
  13. Yoon YS, Lee CH, Kang YA, Kwon SY, Yoon HI, Lee JH, Lee CT. Impact of toxocariasis in patients with unexplained patchy pulmonary infiltrate in Korea. J Korean Med Sci. 2009;24:40–5.
    Article PubMed Central PubMed Google Scholar
  14. Kang YR, Kim SA, Jeon K, Koh WJ, Suh GY, Chung MP, Kim H, Kwon OJ, Kang ES, Um SW. Toxocariasis as a cause of new pulmonary infiltrates. Int J Tuberc Lung Dis. 2013;17:412–7.
    Article CAS PubMed Google Scholar
  15. Ribeiro JD, Fischer GB. Eosinophilic lung diseases. Paediatr Respir Rev. 2002;3:278–84.
    Article PubMed Google Scholar
  16. Woodhall DM. Toxocariasis. In: Magill AJ, Ryan ET, Hill DR, Solomon T, editors. Hunter’s tropical medicine and emerging infectious diseases. 9th ed. Philadelphia: Saunders Elsevier; 2013. p. 850–2.
    Chapter Google Scholar

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Authors and Affiliations

  1. Division of Pulmonary Medicine, Department of Medicine, Cooper Medical School of Rowan University, Cooper University Hospital, 3 Cooper Plaza, Suite 312, Camden, NJ, 08103, USA
    G. Ranasuriya & Z. Boujaoude
  2. Division of Infectious Diseases, Department of Medicine, Cooper Medical School of Rowan University, Cooper University Hospital, Camden, NJ, USA
    A. Mian & C. Tsigrelis

Authors

  1. G. Ranasuriya
  2. A. Mian
  3. Z. Boujaoude
  4. C. Tsigrelis

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Correspondence toG. Ranasuriya.

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Ranasuriya, G., Mian, A., Boujaoude, Z. et al. Pulmonary toxocariasis: a case report and literature review.Infection 42, 575–578 (2014). https://doi.org/10.1007/s15010-014-0587-3

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